scholarly journals Effects of Mandibular Advancement plus Prohibition of Lower Incisor Movement on Mandibular Growth in Rats

2009 ◽  
Vol 79 (6) ◽  
pp. 1095-1101 ◽  
Author(s):  
Koji Taira ◽  
Shoichiro Iino ◽  
Takeshi Kubota ◽  
Tomohiro Fukunaga ◽  
Shouichi Miyawaki
Keyword(s):  
Experimental Period ◽  
Mandibular Advancement ◽  
Functional Appliance ◽  
Lower Incisor ◽  
Mandibular Growth ◽  
Fixed Group ◽  
Fixed Functional Appliance ◽  
And Control ◽  
Ramus Height ◽  
Lower Incisors

Abstract Introduction: To test the hypothesis that mandibular advancement with the use of a fixed functional appliance combined with prohibition of labial movement of the lower incisors will have no effect on mandibular growth in growing rats. Materials and Methods: Fifteen 4-week-old male rats were divided into fixed, unfixed, and control groups (n = 5, each). Bite-jumping appliances were used in the fixed and unfixed groups. Sites of bone perforation and the lower incisors were connected with ligature wires in the fixed group. The ramus height, mandibular length, and inclination of lower incisors were examined for 4 weeks, and those values were compared among five intervals and three groups by through one-way analysis of variance models and the Bonferroni multiple comparison test for post hoc comparison. Results: Increases in ramus height and mandibular length during the experimental period were 1.5 mm and 2.5 mm in the fixed group, 1 mm and 1.5 mm in the unfixed group, and 1.2 mm and 1.9 mm in the control group, respectively. Growth of ramus height and growth of mandibular length in the fixed group were greater than in the unfixed and control groups during the experimental period. The inclination of lower incisors in the unfixed group was increased 8.0 degrees throughout the experimental period, which differed from results obtained in the other groups. Conclusions: Mandibular growth was accelerated effectively before and during the pubertal period in rats by mandibular advancement with a fixed functional appliance combined with prohibition of labial movement of the lower incisor.

scholarly journals Therapeutic effectiveness of AdvanSync2 at different stages of skeletal maturity in skeletal Class II malocclusion: A single-blind clinical trial

2020 ◽  
Vol 10 ◽  
pp. 111-119
Author(s):  
Pradeep Raghav ◽  
Shivani Mathur ◽  
Kumar Amit ◽  
Stuti Mohan
Keyword(s):  
Skeletal Maturity ◽  
Class Ii ◽  
Functional Appliance ◽  
Functional Therapy ◽  
Lower Incisor ◽  
Skeletal Class ◽  
Fixed Functional Appliance ◽  
Skeletal Class Ii ◽  
Group A ◽  
Group B

Objectives: AdvanSync2 (Ormco, Glendora, California, USA) is a molar-to-molar fixed Class II corrector, based on the philosophy of Herbst which allows the bonding of the both upper and lower arches simultaneously along with fixed functional therapy. The purpose of this study was to cephalometrically compare the skeletal and dentoalveolar effects of AdvanSync2 in the correction of Class II malocclusions in circumpubertal and post-pubertal patients. Materials and Methods: Forty-eight samples were selected and divided into two groups based on their CVMI staging, Group A, i.e., at CVMI Stages 2 and 3 (18 girls and six boys) and Group B, i.e., CVMI Stages 4, 5, and 6 (19 girls and five boys). Cephalograms taken at pre- and post-AdvanSync2 stages were compared and analyzed. Results: The results showed that there was a significant increase in mandibular length in both groups. Both the groups also showed sagittal maxillary restriction, maxillary molar distalization, and retroclination of maxillary incisors. On comparison between Group A and Group B, there was no statistically significant differences in terms of maxillary position, size of maxilla, as well as upper and lower incisor inclinations in Group A except for improvement of mandibular position (SNB; P ≤ 0.01) and greater amount of chin growth (B -Pg; P ≤ 0.01) with respect to Group B. Conclusion: AdvanSync2 can be used as an effective fixed functional appliance in post-pubertal group for sagittal mandibular correction in skeletal Class II patients.

scholarly journals Effects of miniplate anchored and conventional Forsus Fatigue Resistant Devices in the treatment of Class II malocclusion

2016 ◽  
Vol 86 (6) ◽  
pp. 1026-1032 ◽  
Author(s):  
Hakan Turkkahraman ◽  
Sule Kocabas Eliacik ◽  
Yavuz Findik
Keyword(s):  
Side Effects ◽  
Class Ii ◽  
Class Ii Malocclusion ◽  
Lower Incisor ◽  
Mandibular Growth ◽  
Treatment Groups ◽  
Group 15 ◽  
Group A ◽  
Lower Incisors ◽  
Stimulation Of

ABSTRACT Objective: To compare the skeletal, dentoalveolar, and soft tissue effects of the miniplate anchored Forsus Fatigue Resistant Device (FRD) and the conventional Forsus FRD in the treatment of Class II malocclusion. Materials and Methods: The study was carried out with 30 patients (10 girls, 20 boys). In the MA-Forsus group, 15 patients (2 girls, 13 boys) were treated with a miniplate anchored Forsus FRD for 9.40 ± 2.25 months. In the C-Forsus group, 15 patients (8 girls, 7 boys) were treated with a conventional Forsus FRD for 9.46 ± 0.81 months. A total of 16 measurements were calculated and statistically analyzed to find intragroup and intergroup differences. Results: Statistically significant differences were found between the groups in IMPA, SN/Occ, SN/GoGn, overjet, overbite, and Li-S measurements (P < .05). In the C-Forsus group, a substantial amount of lower incisor protrusion was observed, whereas retrusion was found in the MA-Forsus group (P < .001). The mandible rotated backward in the MA-Forsus group, whereas it remained unchanged in the C-Forsus group (P < .05). Reductions in overjet (P < .001) and overbite were greater in the C-Forsus group (P < .05). Conclusion: Stimulation of mandibular growth and inhibition of maxillary growth were achieved in both treatment groups. In the C-Forsus group, a substantial amount of lower incisor protrusion was observed, whereas retrusion of lower incisors was found in the MA-Forsus group. The MA-Forsus group was found to be more advantageous as it had no dentoalveolar side effects on mandibular dentition.

scholarly journals Fixed Functional Appliances

2021 ◽  
Vol 10 (31) ◽  
pp. 2499-2504
Author(s):  
Nandalal Girijalal Toshniwal ◽  
Pooja Changdev Katkade ◽  
Shubhangi Amit Mani ◽  
Nilesh Mote
Keyword(s):  
Class Ii ◽  
Masticatory Muscles ◽  
Mandibular Advancement ◽  
Emg Activity ◽  
Functional Appliance ◽  
Fixed Functional Appliance ◽  
Functional Appliances ◽  
Mandibular Protrusion ◽  
Emg Electrodes ◽  
Class Ii Elastics

Considering the large number of fixed functional appliances, choosing the best device for your patient is not an easy task. To describe the development of fixed functional appliances as well as our 20-year experience working with them. Fixed functional appliances are grouped into flexible, rigid and hybrid. They are different appliances, whose action is described here. Four clinical cases will be reported with a view in illustrating the different appliances. Rigid fixed functional appliances provide better skeletal results than flexible and hybrid ones. Flexible and hybrid appliances have similar effects to those produced by class II elastics. They ultimately correct class II with dentoalveolar changes. From a biomechanical standpoint, fixed functional appliances are more recommended to treat class II in dolichofacial patients, in comparison to class II elastics. The electromyographic (EMG) activity of masticatory muscles was monitored longitudinally with chronically implanted EMG electrodes to determine whether functional appliances produce a change in postural EMG activity of the muscles. Pre-appliance and post-appliance EMG levels in four experiments that had been fitted with functional appliances were compared against the background of EMG levels in controls without appliances. The insertion of two types of functional appliance to induce mandibular protrusion was associated with a decrease in postural EMG activity of the superior and inferior heads of the lateral pterygoid, superficial masseter, and anterior digastric muscles; the decrease in the first three muscles was statistically significant. This decreased postural EMG activity persisted for approximately 6 weeks, with a gradual return towards pre-appliance levels during a subsequent 6-week period of observation. Progressive mandibular advancement of 1.5 to 2 mm every 10 to 15 days did not prevent the decrease in postural EMG activity. KEY WORDS Orthodontics, Class II Malocclusion, Fixed Functional Appliance.

scholarly journals Effects of fixed functional therapy on tongue and hyoid positions and posterior airway

2013 ◽  
Vol 84 (2) ◽  
pp. 260-264 ◽  
Author(s):  
Fulya Ozdemir ◽  
Feyza Ulkur ◽  
Didem Nalbantgil
Keyword(s):  
Retrospective Study ◽  
Class I ◽  
Occlusal Plane ◽  
Functional Appliance ◽  
Functional Therapy ◽  
Lower Incisor ◽  
Time Points ◽  
Fixed Functional Appliance ◽  
Incisor Inclination ◽  
Airway Dimensions

ABSTRACT Objective: To evaluate how therapy with a fixed functional appliance affects airway dimensions, dentoalveolar changes, and tongue and hyoid positions. Materials and Methods: A retrospective study was carried out on 46 pre- and posttreatment lateral cephalometric radiographs of 23 post-peak Class II patients (12 girls, 11 boys) treated with a Forsus Fatigue Resistant Device (FRD) appliance. The radiographies were taken at the start and at the end of Forsus FRD appliance therapy when a Class I or overcorrected Class I canine and molar relationship was achieved. The process took an average of 5 months 13 days ± 1 month 4 days. Skeletal and dental parameters were measured using Dolphin software, and the sagittal airway area was measured by AutoCAD software. Results: Analyses of the pre- and posttreatment means revealed that there was no statistically significant skeletal correction of the sagittal malocclusion; increase of lower incisor inclination, decrease of upper incisor inclination, decrease of interincisal angle, and rotation of occlusal plane all contributed to the reduction of overjet. The tongue area and intermaxillary space area increased in response to these dentoalveolar changes; however, there was no statistically significant change in the hyoid position or the oropharyngeal area between the two time points. Conclusions: The dentoalveolar changes produced by Forsus FRD appliance did not cause any significant posterior airway changes in young adult patients.

scholarly journals Management of Class II Division 1 Subdivision malocclusion using unilateral bicuspid extractions and fixed functional appliance: A Two Year Follow-Up

2021 ◽  
Vol 8 (1) ◽  
pp. 12-19
Author(s):  
Sarvraj Kohli ◽  
Virinder Kohli ◽  
Gagan Deep Kochhar
Keyword(s):  
Class Ii ◽  
Mandibular Advancement ◽  
Treatment Modalities ◽  
Functional Appliance ◽  
Skeletal Class ◽  
Fixed Functional Appliance ◽  
Skeletal Class Ii ◽  
Division 1 ◽  
Unique Approach ◽  
Class Ii Division 1

Introduction:  Management of Class II Subdivision cases pose a clinical dilemma and require a careful diagnosis to ascertain the source of asymmetry. Various treatment modalities involving: different protocols of tooth extractions; molar distalization; fixed functional appliances or orthognathic surgery have been proposed for the same. Objective:       This article reports a unique approach for management of a severe skeletal Class II with Angle’s Class II Division 1 subdivision malocclusion using unilateral bicuspid extractions in mandibular and maxillary arches  and a fixed functional appliance. Results:         A 13 year 1 month old male in CVMI transition stage was successfully treated. Extraction of #44 was done to alleviate crowding in the mandibular anterior region and #15 was extracted to protract #16 to achieve a Class II molar relationship. A pre-functional Class II molar and canine relationship with co-incident midlines was achieved. The functional phase consisted of a fixed functional appliance (Forsus FRD) for mandibular advancement to correct the severe skeletal Class II. Class I molar and canine relationships were achieved with reduction of facial convexity and overjet. Result remained stable 24 months after treatment. The improvement can be quantified by the reduction in scores of orthodontic indices measured pre and post treatment. Conclusions:                        Management of Class II subdivision malocclusion requires careful planning. This paper presents a unique approach utilizing unilateral extractions and fixed functional appliance to address severe skeletal Class II discrepancy and the subdivision dilemma.

scholarly journals Effects of growth hormone and functional appliance on mandibular growth in an adolescent rat model

2018 ◽  
Vol 88 (5) ◽  
pp. 624-631 ◽  
Author(s):  
Shuai Wang ◽  
Lu Ye ◽  
Mei Li ◽  
Han Zhan ◽  
Rui Ye ◽  
...  
Keyword(s):  
Growth Hormone ◽  
Rat Model ◽  
Synergistic Effects ◽  
Recombinant Human Growth Hormone ◽  
Human Growth ◽  
Mandibular Advancement ◽  
Control Group ◽  
Functional Appliance ◽  
Condylar Cartilage ◽  
Mandibular Growth

ABSTRACT Objectives: To investigate the individual and synergistic effects of growth hormone (GH) and functional appliance (FA) on mandibular growth in an adolescent rat model. Materials and Methods: Forty adolescent (6-week-old) female Wistar rats were randomly divided into four groups (10 rats in each group). The control group received a sham treatment (intra-abdominal injection of phosphate-buffered saline), the GH group received an intra-abdominal injection of recombinant human growth hormone, the FA group was treated with a mandibular advancement device, and the GH+FA group received both the GH and FA treatments. The amount of mandibular growth in each group was measured quantitatively using cone-bean computed tomography. The growth of condylar cartilage and expression of matrix metalloproteinases–1 and –13 (MMP-1 and MMP-13) and type II and X collagen (Col II and Col X) were assessed using histological staining and immunostaining techniques. Results: After 4 weeks, there was significant mandibular growth in the FA group compared with the control group (P < .05). The GH+FA group had significantly greater mandibular length, thickness of condylar cartilage, and expression of MMP-1, MMP-13, Col II, and Col X in the cartilage than the other groups (P < .05). The GH+FA group and GH group had significantly greater weight than the FA and control groups (P < .05). Conclusions: The FA as well as GH+FA stimulated mandibular growth in adolescent rats.

scholarly journals Administration of GnRH at Onset of Estrus, Determined by Automatic Activity Monitoring, to Improve Dairy Cow Fertility during the Summer and Autumn

Animals ◽  
2021 ◽  
Vol 11 (8) ◽  
pp. 2194
Author(s):  
Zvi Roth ◽  
Yaron Z. Kressel ◽  
Yaniv Lavon ◽  
Dorit Kalo ◽  
David Wolfenson
Keyword(s):  
Metabolic Diseases ◽  
Experimental Period ◽  
Visual Observation ◽  
Activity Monitoring ◽  
Least Square ◽  
Gnrh Analogue ◽  
Automatic Activity ◽  
Effect Of Treatment ◽  
Uterine Diseases ◽  
And Control

We examined gonadotropin-releasing hormone (GnRH) administration at onset of estrus (OE), determined by automatic activity monitoring (AAM), to improve fertility of dairy cows during the summer and autumn. The study was performed on two dairy farms in Israel. The OE was determined by AAM recorded every 2 h, and a single im dose of GnRH analogue was administered shortly after OE. Pregnancy was determined by transrectal palpation, 40 to 45 d after artificial insemination (AI). Conception risk was analyzed by the GLIMMIX procedure of SAS. Brief visual observation of behavioral estrus indicated that about three-quarters of the events (n = 40) of visually detected OE occurred within 6 h of AAM-detected OE. Accordingly, the GnRH analogue was administered within 5 h of AAM-detected OE, to overlap with the expected endogenous preovulatory LH surge. Overall, pregnancy per AI (P/AI) was monitored over the entire experimental period (summer and autumn) in 233 first, second or third AI (116 and 117 AI for treated and control groups, respectively). Least square means of P/AI for treated (45.8%) and control (39.4%) groups did not differ, but group-by-season interaction tended to differ (p = 0.07), indicating no effect of treatment in the summer and a marked effect of GnRH treatment (n = 58 AI) compared to controls (n = 59 AI) on P/AI in the autumn (56.6% vs. 28.5%, p < 0.03). During the autumn, GnRH-treated mature cows (second or more lactations), and postpartum cows exhibiting metabolic and uterine diseases, tended to have much larger P/AI than their control counterparts (p = 0.07–0.08). No effect of treatment was recorded in the autumn in first parity cows or in uninfected, healthy cows. In conclusion, administration of GnRH within 5 h of AAM-determined OE improved conception risk in cows during the autumn, particularly in those exhibiting uterine or metabolic diseases postpartum and in mature cows. Incorporation of the proposed GnRH treatment shortly after AAM-detected OE into a synchronization program is suggested, to improve fertility of positively responding subpopulations of cows.

scholarly journals Assessment Of Stress On Serum Estradiol Levels In Female Subordinate Naked Mole Rats Following Isolation From Natal Colony

2019 ◽  
Author(s):  
AMOS ONYANSI MAKORI ◽  
A. W. NYONGESA ◽  
H. ODONGO ◽  
R. J. MASAI
Keyword(s):  
Social Stress ◽  
Experimental Period ◽  
Reproductive Suppression ◽  
Significance Level ◽  
Elisa Technique ◽  
Female Subordinate ◽  
Set Up ◽  
And Control ◽  
Assessment Of Stress ◽  
Hormonal Analysis

Abstract Objective: This study investigated the effects of isolation of subordinate naked mole rats from natal colonies on their reproductive success. The study aimed at establishing whether the reproductive suppression in subordinate naked mole rats is the outcome of social stress exerted by breeding female in the colony or other unknown environmental factors within the colony set-up. Blood samples from experimental and control groups were collected on 2nd, 4th, 6th , 8th, 12th and 20th weeks of experimental period for hormonal analysis using ELISA technique. The Statistical analysis done using student t-test at 5% significance level. Results: Hormone analysis showed significant change in both cortisol (t = 8.74, P=0.01) and estradiol (t=7.15, P=0.02) of subordinate isolated females. Results showed no correlation between stress and cyclicity. Conclusively, the observed reproductive suppression among subordinate naked mole rats in natal colonies is probably due to presence of queen or other reproductive aspects that may not be directly related to stress.

An innovative jig to prevent canine bracket breakage during fixed functional appliance therapy

2016 ◽  
Vol 50 (2) ◽  
pp. 128-129
Author(s):  
Abhishek Choudhary ◽  
Amitabh Kallury ◽  
Chandresh Shukla ◽  
Ankur Chaukse
Keyword(s):  
Functional Appliance ◽  
Fixed Functional Appliance

scholarly journals Biocompatibility and Mineralization Activity of Three Calcium Silicate-Based Root Canal Sealers Compared to Conventional Resin-Based Sealer in Human Dental Pulp Stem Cells

Materials ◽  
2019 ◽  
Vol 12 (15) ◽  
pp. 2482 ◽  
Author(s):  
Deog-Gyu Seo ◽  
Donghee Lee ◽  
Yong-Min Kim ◽  
Dani Song ◽  
Sin-Young Kim
Keyword(s):  
Cell Migration ◽  
Root Canal ◽  
Calcium Silicate ◽  
Dental Pulp ◽  
Experimental Period ◽  
Control Groups ◽  
Human Dental Pulp ◽  
Ah Plus ◽  
And Control ◽  
Root Canal Sealers

The purpose of this study was to compare the cytotoxic effects and mineralization activity of three calcium silicate-based root canal sealers to those of a conventional resin-based sealer. Experiments were performed using human dental pulp stem cells grown in a monolayer culture. The root canal sealers tested in this study were EndoSequence BC Sealer (Brasseler), BioRoot RCS (Septodont), Endoseal MTA (Maruchi), and AH Plus (Dentsply DeTrey). Experimental disks 6 mm in diameter and 3 mm in height were made and stored in a 100% humidity chamber at 37 °C for 72 h to achieve setting. The cytotoxicity of various root canal sealers was evaluated using a methyl-thiazoldiphenyl-tetrazolium (MTT) assay. To evaluate cell migration ability, a scratch wound healing method was used, and images of the scratch area were taken using a phase-contrast microscope. Cell morphology was evaluated by a scanning electron microscope after direct exposure for 72 h to each sealer disk. In the cell viability assay, there were no significant differences between the EndoSequence BC, BioRoot RCS, Endoseal MTA, and control groups in any experimental period (p > 0.05). In the cell migration assay, there were no significant differences between the EndoSequence BC, Endoseal MTA, and control groups in any experimental period (p > 0.05). BioRoot RCS exhibited slower cell migration relative to EndoSequence BC and Endoseal MTA for up to 72 h (p < 0.05). Conversely, it showed a similar wound healing percentage at 96 h (p > 0.05). In an evaluation of cell morphology, cells in direct contact with EndoSequence BC, BioRoot RCS, and Endoseal MTA disks showed superior spreading compared to those in contact with the AH Plus disk. In an Alizarin red staining assay, EndoSequence BC, BioRoot RCS, and Endoseal MTA showed a significant increase in mineralized nodule formation compared to the AH Plus group (p < 0.05). In conclusion, all calcium silicate-based root canal sealers tested in this study showed good biological properties and mineralization activity compared to conventional resin-based sealer.

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