scholarly journals Xenotransplantation: history, problems and development prospects

Author(s):  
V. A. Gulyaev ◽  
M. Sh. Khubutiya ◽  
M. S. Novruzbekov ◽  
A. S. Mironov ◽  
O. D. Olisov ◽  
...  

The paper reviews the milestones and prerequisites in the history of the emergence and development of xenotransplantation. The currently existing barriers (immunological, infectious, genetic, ethical, and regulatory) to the development of this organ and tissue transplantation type have been studied. Available data on theoretical research and experimental studies have been reviewed. The prospects for performing xenotransplantation in various combination of species have been assessed. The forms and variants of the xenograft rejection reaction have been described. Genetic engineering approaches to overcoming xenoimmunological incompatibility are described. An assessment is made of ways to overcome existing barriers and prospects for the further development of xenotransplantation as a scientific section of transplantology.

2018 ◽  
Vol 8 (7) ◽  
pp. 2241
Author(s):  
Svetlana Stepanovna SHEVCHUK ◽  
Nazima Shafievna IBRAGIMOVA ◽  
Galina Olegovna BELANOVA ◽  
Mariya Alekseevna MALYKHINA ◽  
Svetlana Nikolaevna IVAKHNENKO

This paper is devoted to research and analysis of the issues on legal regulation of the relations arising in connection with the removal of human organs or tissues with the purpose of their subsequent transplantation to a donor. The current national legal framework and lawenforcement practice in transplantation relations are investigated. The theoretical and practical problems affecting the provision and protection of the rights and interests of parties to these relations are analyzed. The necessity of further development and improvement of legal regulation of transplantation relations is substantiated. The scientific novelty of the work is that the authors, on the basis of studying the history of the formation and development of the institution of human organ and tissue transplantation, have made attempts to identify the main trends and directions of legislative support of this sphere of social relations and to substantiate the most constructive proposals in order to improve the corresponding mechanism of legal regulation.


Author(s):  
Olga Chertovskikh ◽  
Matvey Chertovskikh

The article focuses on the issue of introduction of AI technology into the modern journalism. The topic proves to be of relevant importance as both mass media and press services reveal their direct dependence on the technological development level of the human society. It means that any new relevant technology can change the whole system. The objective of the article is to research the issue of Artificial Intelligence introduction into the modern journalism. The authors consider the history of the “smart machines” creation. Furthermore, they describe the current situation in the sphere of journalism, bring some specific examples of the existing and the projected systems and highlight the areas of possible practical application and the development prospects. They also obtain information on the main principles of the operation, the algorithms, the goals and the capabilities of the machines. In addition, the authors consider the advantages and the risks of this state-of-the-art technology, analyze the cultural and the psychological aspects of its mass introduction, make predictions concerning the prospects for the further development of this sphere, consider different scenarios of its development and identify the challenges and the advantages for the profession of a journalist. In conclusion, the authors state that despite the fact that AI in journalism is a mass phenomenon, all the projects of the introduction of Artificial Intelligence are not currently posing a direct threat to the profession. However, the fact that the mass media of different countries are starting to actively apply AI in journalism, emphasizes the relevance and the importance of further research in this sphere.


Author(s):  
E.P. Bogdanova

The article is devoted to the study of the history of formation and development of the institution of self-defense. The analysis of the sources of law of foreign countries and Russia from ancient times to the present, which reflect the legal regulation of the institution under study, has been carried out. It is noted that the purpose of self-defense is expressed in the ability of a right holder to independently influence the offender by the means prescribed by law, with the help of which the suppression, prevention, elimination and restoration of the violated right can be achieved. In different periods of the Russian legal system formation, a gradual development and improvement of the institution of self-defense was observed, which was also enshrined in modern legislation of the country. The article discusses the various points of view of Russian scientists on the studied issues. Given the debatability of domestic scientific research in this area, the need for further theoretical research of the institution of self-defense is noted, taking into account the results obtained by scientists at different time periods. The need for further development of modern legislation governing the institution under study is also noted.


Author(s):  
Sergey Vasil'ev ◽  
Vyacheslav Schedrin ◽  
Aleksandra Slabunova ◽  
Vladimir Slabunov

The aim of the research is a retrospective analysis of the history and stages of development of digital land reclamation in Russia, the definition of «Digital land reclamation» and trends in its further development. In the framework of the retrospective analysis the main stages of melioration formation are determined. To achieve the maximum effect of the «digital reclamation» requires full cooperation of practical experience and scientific potential accumulated throughout the history of the reclamation complex, and the latest achievements of science and technology, which is currently possible only through the full digitalization of reclamation activities. The introduction of «digital reclamation» will achieve greater potential and effect in the modernization of the reclamation industry in the «hightech industry», through the use of innovative developments and optimal management decisions.


2020 ◽  
Vol 26 (6) ◽  
pp. 1283-1296
Author(s):  
K.A. Omarieva ◽  
P.G. Isaeva

Subject. The article addresses problems and prospects for the banking supervision development in the Russian Federation under modern conditions. Objectives. We review the essence and methods of organization of the banking supervision, and identify the main problems and prospects for its development. Methods. To provide valid, reliable and reasoned recommendations, we apply normative and integrated approaches to the study of the banking supervision effectiveness in the current circumstances. Results. The paper investigates main problems and development prospects for the Russian banking supervision. The essential importance of supervision comes from the main role of the banking system in maintaining accounts of economic entities and making settlements. Even minor failures or delays in operations can lead to negative outcomes and disastrous consequences for the entire monetary system and the national economy. Therefore, we highlight issues that require attention, and make proposals for further development of the banking supervision. Conclusions. In the context of dynamically developing economy, the banking practice is becoming more complex. As a result, there is a need for new financial instruments that can reduce risks, increase the speed and efficiency of operations and document flow, and help achieve the world levels of introduced standards.


Author(s):  
Bashkim Selmani ◽  
Bekim Maksuti

The profound changes within the Albanian society, including Albania, Kosovo and Macedonia, before and after they proclaimed independence (in exception of Albania), with the establishment of the parliamentary system resulted in mass spread social negative consequences such as crime, drugs, prostitution, child beggars on the street etc. As a result of these occurred circumstances emerged a substantial need for changes within the legal system in order to meet and achieve the European standards or behaviors and the need for adoption of many laws imported from abroad, but without actually reading the factual situation of the psycho-economic position of the citizens and the consequences of the peoples’ occupations without proper compensation, as a remedy for the victims of war or peace in these countries. The sad truth is that the perpetrators not only weren’t sanctioned, but these regions remained an untouched haven for further development of criminal activities, be it from the public state officials through property privatization or in the private field. The organized crime groups, almost in all cases, are perceived by the human mind as “Mafia” and it is a fact that this cannot be denied easily. The widely spread term “Mafia” is mostly known around the world to define criminal organizations.The Balkan Peninsula is highly involved in these illegal groups of organized crime whose practice of criminal activities is largely extended through the Balkan countries such as Kosovo, Albania, Macedonia, Serbia, Bosnia, Croatia, Montenegro, etc. Many factors contributed to these strategic countries to be part of these types of activities. In general, some of the countries have been affected more specifically, but in all of the abovementioned countries organized crime has affected all areas of life, leaving a black mark in the history of these states.


2020 ◽  
Vol 963 (9) ◽  
pp. 30-43
Author(s):  
M.Yu. Orlov

Studying the current state of cartography and ways of further developing the industry, the role of the map in the future of the society, new methods of promoting cartographic products is impossible without a deep scientific analyzing all the paths, events and factors influencing its formation and development throughout all the historic steps of cartographic production in Russia. In the article, the history of cartographic production in Russia is considered together with the development of private, state and military cartography, since, despite some differences, they have a common technical, technological and production basis. The author describes the stages of originating, formation and growth of industrial cartographic production from the beginning of the XVIII century until now. The connection between the change of political formations and technological structures with the mentioned stages of maps and atlases production is considered. Each stage is studied in detail, a step-by-step analysis was carried out, and the characteristics of each stage are described. All the events and facts are given in chronological order, highlighting especially significant moments influencing the evolution of cartographic production. The data on the volumes of printing and sales of atlases and maps by commercial and state enterprises are presented. The main trends and lines of further development of cartographic production in Russia are studied.


Sensors ◽  
2021 ◽  
Vol 21 (11) ◽  
pp. 3609
Author(s):  
Mykola Sysyn ◽  
Michal Przybylowicz ◽  
Olga Nabochenko ◽  
Lei Kou

The ballasted track superstructure is characterized by a relative quick deterioration of track geometry due to ballast settlements and the accumulation of sleeper voids. The track zones with the sleeper voids differ from the geometrical irregularities with increased dynamic loading, high vibration, and unfavorable ballast-bed and sleeper contact conditions. This causes the accelerated growth of the inhomogeneous settlements, resulting in maintenance-expensive local instabilities that influence transportation reliability and availability. The recent identification and evaluation of the sleeper support conditions using track-side and on-board monitoring methods can help planning prevention activities to avoid or delay the development of local instabilities such as ballast breakdown, white spots, subgrade defects, etc. The paper presents theoretical and experimental studies that are directed at the development of the methods for sleeper support identification. The distinctive features of the dynamic behavior in the void zone compared to the equivalent geometrical irregularity are identified by numeric simulation using a three-beam dynamic model, taking into account superstructure and rolling stock dynamic interaction. The spectral features in time domain in scalograms and scattergrams are analyzed. Additionally, the theoretical research enabled to determine the similarities and differences of the dynamic interaction from the viewpoint of track-side and on-board measurements. The method of experimental investigation is presented by multipoint track-side measurements of rail-dynamic displacements using high-speed video records and digital imaging correlation (DIC) methods. The method is used to collect the statistical information from different-extent voided zones and the corresponding reference zones without voids. The applied machine learning methods enable the exact recent void identification using the wavelet scattering feature extraction from track-side measurements. A case study of the method application for an on-board measurement shows the moderate results of the recent void identification as well as the potential ways of its improvement.


Entropy ◽  
2021 ◽  
Vol 23 (2) ◽  
pp. 141
Author(s):  
Reinhard Folk

The Conferences of the Middle European Cooperation in Statistical Physics (MECO) were created as an attempt to establish and maintain an exchange between scientists in the fields of statistical and condensed matter physics from Western and Eastern countries, overcoming the hurdles of the Iron Curtain. Based on personal remembrance and historical resources, the genesis and further development of MECO meetings is described. The annual meetings were interrupted in 1991 by the Yugoslav War but were re-established in 1993 and continue today. Although the fall of the Iron Curtain and the European Research programs changed the situation for the meetings considerably, the ties created by MECO still are useful to help scientific exchange. The history of European (and not only) statistical physics and the history of the MECO are tightly intertwined. It started in a time where an essential breakthrough has been achieved in statistical physics describing the features near phase transitions. In addition to the merging of solid-state physics and field theory concepts, the application of numerical methods (Monte Carlo methods) added a new pillar besides exact solutions and experiments to check theoretical models. In the following, the scientific emphasis (in general) has changed from the traditional fields of the first MECO to complexity and interdisciplinary themes as well.


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