scholarly journals Capitalizing the Tourist Potential in Caraş-Severin County as a Premise for Regional Entrepreneurial Development

2021 ◽  
Vol 66 (2) ◽  
pp. 61-78
Author(s):  
Venera Cristina Manciu ◽  
◽  
Suzana Demyen ◽  
Keyword(s):  
The Sustainable Development ◽  
Tourist Attractions ◽  
Media Impact ◽  
Intangible Heritage ◽  
Starting Point ◽  
Steep Decline ◽  
Widespread Phenomenon ◽  
Tourism Potential ◽  
High Level ◽  
Future Business

In the context when tourism has become a widespread phenomenon, there are many global concerns in this regard, with reference to the plans to protect the world’s cultural and natural assets, and to stimulate the sustainable development of this sector. Touristic, cultural and scientific bodies develop comprehensive strategies, initiating Conventions, drawing up plans and periodically preparing reports. Romania has a large number of tourist attractions, ranking 46th in the top based on this criterion, distinguishing itself also grace to the attractiveness of natural objectives, the total number of protected areas, the number of cultural objectives and the number of objectives in terms of oral and intangible heritage. Taking into account all these indicators, Romania may be proud of a vast touristic potential, which offers wonderful premises for starting a business in tourism, for the expansion of entrepreneurship and for the development of natural, cultural and anthropic resources. Each region and area of Romania has diverse and special particularities and characteristics, and we have to underscore their ability to become true business poles grace to the high level of their attractiveness, being capably of developing actual hospitality industries. The recognition of their existence and value obviously contributes to a very large extent to the promotion and inclusion of cultural objectives into various global rankings, actions that lead to an increased interest among tourists, and implicitly contribute to attracting a large number of visitors and generally have a significant media impact. In this respect, this paper highlights international and domestic coordinates related to the sizing and capitalization of tourism potential, analysing theoretical coordinates and statistical data. In addition, we also forward the results of a survey carried out in order to identify the prospects for capitalizing on the Romanian tourist heritage and the manner in which the highlighting of the Romanian touristic and cultural objectives can be a starting point for generating prosperous future business and can develop the business milieu in all areas, including in the regions experiencing a steep decline, like Caraş-Severin county. Key words: touristic sight, tourist attractions, business, hospitality industry, entrepreneurship JEL: Z32, L26

Her Majesty Queen Rania Al Abdullah

2019 ◽  
Author(s):  
Adib Rifqi Setiawan
Keyword(s):  
Education System ◽  
Ministry Of Education ◽  
Childhood Experiences ◽  
The Sustainable Development ◽  
American University ◽  
The North ◽  
The World ◽  
Development Goals ◽  
High Level ◽  
Education And Development

“The real treasure is in the minds of our children, and all we have to do is extract it.” Her Majesty Queen Rania Al Abdullah writes in website Queen Rania Foundation For Education And Development www.qrf.org/en. Rania Al Yassin was born on August 31, 1970. She obtained her Bachelor’s degree in Business Administration from the American University of Cairo in 1991. She applied this, first, to a banking career in Jordan and, later, to the information technology sector. After marrying Prince Abdullah bin Al Hussein on June 10, 1993, they went on to have four children: Prince Hussein, Princess Iman, Princess Salma, and Prince Hashem. In addition to being a wife and mother, Queen Rania works hard to lift the lives of Jordanians by supporting their endeavours and helping to create new opportunities for them. Locally, she is committed to breathe new life into the public education system; empower communities and women especially through microfinance initiatives; protect children and families; and drive innovation, technology and entrepreneurship, especially amongst young people. Internationally, Queen Rania is an advocate for tolerance, compassion and bridge building between people of all cultures and backgrounds. Her efforts to simultaneously challenge stereotypes of Arabs and Muslims, and promote greater understanding and acceptance between people of all faiths and cultures, have won her global recognition. Her Majesty’s passion is education. She believes that every Jordanian girl and boy, and all children, should have access not only to stimulating classrooms and modern curricula, but inspiring teachers and technology that can connect Jordan’s children to the world and the world to Jordan’s children. Her efforts in the education sector complement the work of the Ministry of Education through initiatives such as the Jordan Education Initiative, the Queen Rania Teachers Academy, Madrasati, Edraak and others. To realize these and so much more, Queen Rania has encouraged private sector partners to drive improvements and strengthen the foundations of Jordan’s education system. Queen Rania is also a global voice for access to quality education for children around the world. In 2009, Her Majesty championed the 1 Goal campaign for education; she is Honorary Chair of the UN Girl’s Education Initiatives and has advocated access to education in forums and gatherings around the world. Her work and her efforts to improve the learning opportunities for children have been recognized at the highest levels, nationally, regionally and internationally. Additionally, through her position on their boards, Her Majesty contributes to the work of the United Nations Fund and the World Economic Forum. She is the Eminent Advocate for UNICEF; and she was part of the UN appointed High Level Panel who advised on the shape and content of the Sustainable Development Goals which aim to improve the lives of millions of people before 2030. In recognition of her work, Her Majesty has humbly accepted many awards, locally, regionally and globally. These include the Walther Rathenau Award from the Walther RathenauInstitut in Germany for her efforts to greater peace and understanding; the James C. Morgan Global Humanitarian Award from Tech Awards, USA; the Arab Knight of Giving Award from Arab Giving Forum, UAE; the North South Prize by the North South Prize, Portugal; as well as the YouTube Visionary Award. Her Majesty authored several books primarily for children including the Sandwich Swap, which was inspired by her own childhood experiences.

scholarly journals Establishing a consensus for the hallmarks of cancer based on gene ontology and pathway annotations

2021 ◽  
Vol 22 (1) ◽  
Author(s):  
Yi Chen ◽  
Fons. J. Verbeek ◽  
Katherine Wolstencroft
Keyword(s):  
Gene Ontology ◽  
Enrichment Analysis ◽  
Biological Data ◽  
Hallmarks Of Cancer ◽  
High Throughput Analysis ◽  
Knowledge Resources ◽  
Gene Set ◽  
Cancer Hallmarks ◽  
Starting Point ◽  
High Level

Abstract Background The hallmarks of cancer provide a highly cited and well-used conceptual framework for describing the processes involved in cancer cell development and tumourigenesis. However, methods for translating these high-level concepts into data-level associations between hallmarks and genes (for high throughput analysis), vary widely between studies. The examination of different strategies to associate and map cancer hallmarks reveals significant differences, but also consensus. Results Here we present the results of a comparative analysis of cancer hallmark mapping strategies, based on Gene Ontology and biological pathway annotation, from different studies. By analysing the semantic similarity between annotations, and the resulting gene set overlap, we identify emerging consensus knowledge. In addition, we analyse the differences between hallmark and gene set associations using Weighted Gene Co-expression Network Analysis and enrichment analysis. Conclusions Reaching a community-wide consensus on how to identify cancer hallmark activity from research data would enable more systematic data integration and comparison between studies. These results highlight the current state of the consensus and offer a starting point for further convergence. In addition, we show how a lack of consensus can lead to large differences in the biological interpretation of downstream analyses and discuss the challenges of annotating changing and accumulating biological data, using intermediate knowledge resources that are also changing over time.

scholarly journals The Impact of the Implementation of Cohesion Policy on the Sustainable Development of EU Countries

2019 ◽  
Vol 11 (15) ◽  
pp. 4173 ◽  
Author(s):  
Ramona Pîrvu ◽  
Cristian Drăgan ◽  
Gheorghe Axinte ◽  
Sorin Dinulescu ◽  
Mihaela Lupăncescu ◽  
...  
Keyword(s):  
Sustainable Development ◽  
Cohesion Policy ◽  
Member States ◽  
Policy Makers ◽  
The Sustainable Development ◽  
Eu Countries ◽  
Starting Point ◽  
The Impact ◽  
Official Data ◽  
The Eu

The impact of implementation of cohesion policy on the sustainable development of EU countries is of great interest and presents a number of actual challenges. This research aims to evaluate the impact and the effects of the cohesion policy among the Member States using hierarchical clustering analysis in order to identify how the selected variables affect the sustainable development adopted models. The variables used in the analysis were selected on the basis of official data provided by the European Commission, SDG Index and Dashboards Reports and the EU Cohesion Monitor. The results of the research have led to the grouping of the 28 Member States in a number of six clusters, identifying performers but also those countries that have a high potential for sustainable development or which require increased attention to be sustained in recovering existing gaps. The results of the study can be a starting point for policy makers and other stakeholders involved in their efforts to support sustainable development through effective and effective policies.

scholarly journals Progress Assessment and Spatial Heterogeneity Analysis of Water Conservancy Modernization Construction in China

2021 ◽  
Vol 13 (7) ◽  
pp. 3736
Author(s):  
Nan Lu ◽  
Jiwei Zhu ◽  
Hui Chi ◽  
Bing Wang ◽  
Lu Chen
Keyword(s):  
Sustainable Development ◽  
Spatial Heterogeneity ◽  
Sustainable Development Goals ◽  
Water Governance ◽  
Average Score ◽  
The Sustainable Development ◽  
Development Goals ◽  
Water Conservancy ◽  
Index Level ◽  
High Level

To achieve the sustainable development goals established by the United Nations in 2015, China has adopted a series of measures to promote the modernization of water conservancy. However, its construction in China is imbalanced across regions as the endowment of water resources and economic development are distinct. Consequently, it is important to assess the progress of and analyze the spatial heterogeneity of water conservancy modernization construction in China from the perspective of sustainable development goals (SDGs). In this study, 31 regions in China were selected, and data on water conservancy construction in these sampled regions (excluding Hong Kong, Macao, and Taiwan) were collected in 2018. The results show that there exists an imbalanced development in terms of the overall level and the index level. About 60% of the regions scored below the overall average score for China’s current modernization of water conservancy. The eastern areas presented a high level of modernization, while the central, northeast, and western areas showed comparable modernization of water conservancy, all of which lag behind eastern areas of China. Furthermore, China’s water conservancy modernization also presented a strong spatial autocorrelation, and there was at least one deficiency in 55% of the regions, with the rate of deficiencies emerging in the West being much higher than in other regions. In a nutshell, this study provides a novel framework that can be extended to evaluate the SDGs and the effectiveness of water governance in other countries.

A Visit to Rusty Ships. Tourism as a Strategy of Rejuvenating Shrinking Towns in Coastal Areas

2021 ◽  
Vol 14 (3) ◽  
pp. 588-612
Author(s):  
Katarzyna Jarosz ◽  
Hanna Daria Tricoire
Keyword(s):  
Land Use ◽  
Negative Impact ◽  
Coastal Areas ◽  
Shrinking Cities ◽  
Access To Information ◽  
Tourist Attractions ◽  
Environmental Value ◽  
Culture History ◽  
Tourist Infrastructure ◽  
Tourism Potential

The aim of the paper is to analyse, whether and to what degree that tourism is a way of rejuvenating shrinking cities located on the coast. The research is based on three cities, and the adjacent regions, located in Uzbekistan (Mo'noq), Romania (Sulina) and Georgia-Abkhazia (Sukhumi). Tourist attractions connected with nature, culture, history and cuisine are examined, along with the land use and tourist infrastructure. The research indicates that the three sites have great tourism potential, with a focus on nature-oriented tourism. It also suggests that infrastructure, transport, access to information and land use can have a strong, positive or negative impact on tourism attractiveness. Additionally, the threats that uncontrolled tourism can bring are considered - it has been shown that unsustainable tourism and an excessive influx of tourists are threats to the environment and to local societies. A balance between economic and environmental value should therefore be maintained in the process of developing tourism.

scholarly journals Evidence for Inhibition of Topoisomerase 1A by Gold(III) Macrocycles and Chelates TargetingMycobacterium tuberculosisandMycobacterium abscessus

2018 ◽  
Vol 62 (5) ◽  
Author(s):  
Rashmi Gupta ◽  
Carolina Rodrigues Felix ◽  
Matthew P. Akerman ◽  
Kate J. Akerman ◽  
Cathryn A. Slabber ◽  
...  
Keyword(s):  
Mycobacterium Abscessus ◽  
Cross Resistance ◽  
Human Pathogens ◽  
Intrinsic Resistance ◽  
Content Type ◽  
Starting Point ◽  
Scalable Synthesis ◽  
High Level ◽  
Novel Drug

ABSTRACTMycobacterium tuberculosisand the fast-growing speciesMycobacterium abscessusare two important human pathogens causing persistent pulmonary infections that are difficult to cure and require long treatment times. The emergence of drug-resistantM. tuberculosisstrains and the high level of intrinsic resistance ofM. abscessuscall for novel drug scaffolds that effectively target both pathogens. In this study, we evaluated the activity of bis(pyrrolide-imine) gold(III) macrocycles and chelates, originally designed as DNA intercalators capable of targeting human topoisomerase types I and II (Topo1 and Topo2), againstM. abscessusandM. tuberculosis. We identified a total of 5 noncytotoxic compounds active against both mycobacterial pathogens under replicatingin vitroconditions. We chose one of these hits, compound 14, for detailed analysis due to its potent bactericidal mode of inhibition and scalable synthesis. The clinical relevance of this compound was demonstrated by its ability to inhibit a panel of diverseM. tuberculosisandM. abscessusclinical isolates. Prompted by previous data suggesting that compound 14 may target topoisomerase/gyrase enzymes, we demonstrated that it lacked cross-resistance with fluoroquinolones, which target theM. tuberculosisgyrase.In vitroenzyme assays confirmed the potent activity of compound 14 against bacterial topoisomerase 1A (Topo1) enzymes but not gyrase. Novel scaffolds like compound 14 with potent, selective bactericidal activity againstM. tuberculosisandM. abscessusthat act on validated but underexploited targets like Topo1 represent a promising starting point for the development of novel therapeutics for infections by pathogenic mycobacteria.

Achieving the SDGs through interdisciplinary research in global health

2018 ◽  
Vol 47 (8) ◽  
pp. 793-795 ◽  
Author(s):  
Sibylle L Herzig Van Wees ◽  
Mats Målqvist ◽  
Rachel Irwin
Keyword(s):  
Sustainable Development ◽  
Global Health ◽  
Interdisciplinary Research ◽  
Sustainable Development Goals ◽  
Global Health Research ◽  
The Sustainable Development ◽  
Research And Teaching ◽  
Starting Point ◽  
Development Goals ◽  
New Research

The Swedish Global Health Research Conference held in Stockholm, 18–19 April 2018, convened researchers from across Sweden’s universities to foster collaboration and new research. In response to the theme of the conference, How can Sweden contribute to the Sustainable Development Goals? From research to action, many of the plenary and keynote speakers highlighted the importance of interdisciplinary research and teaching. This commentary draws upon a workshop discussing interdisciplinarity, which took place at the conference. Participants included senior professors, lecturers, students and collaborators from the private sector and civil society and we discussed the conceptual and structural challenges that prevent engagement in interdisciplinary research. Although the workshop focused on the Swedish context, issues will be familiar to researchers working outside of Sweden. The 17 Sustainable Development Goals highlight the grand challenges for global society and are intertwined, with progress in one affecting progress in all others. With this starting point, we argue that interdisciplinary research is the way to achieve them. Accordingly, we need to overcome the conceptual and structural challenges that can hinder it. We therefore argue for a paradigm shift of how we value knowledge. We also call for fundamental changes in external and internal (university-level) funding structures, and for the strengthening of interdisciplinary global health teaching.

scholarly journals Experience of Documentation for the Accessibility of Widespread Cultural Heritage

Heritage ◽  
2019 ◽  
Vol 2 (1) ◽  
pp. 1032-1044 ◽  
Author(s):  
Sandro Parrinello ◽  
Anna Dell’Amico
Keyword(s):  
Cultural Heritage ◽  
3D Models ◽  
Complex Objects ◽  
Wide Audience ◽  
Intangible Heritage ◽  
Representation Systems ◽  
Cultural Systems ◽  
Physical Limit ◽  
Starting Point ◽  
The Will

The will to preserve and enhance cultural heritage imposes reflections on databases as containers of information for the accessibility of dispersed heritage. The aim of the research is to validate methodological approaches in order to create 3D models and information systems. These tools improve accessibility to the artifact, according to different interconnection channels, in order to overcome the physical limit imposed by location. Tangible and intangible heritage take the form of a metadata network throughout a critical analysis and elaboration of data. These files create a complex database containing 3D models rich in information that describe cultural systems. The digital survey is the starting point for the development of languages, signs and symbols. It transfers complex objects into virtual systems, developing a multidimensional dialogue capable of integrating actions and meanings. The interactivity of complex databases facilitates the accessibility and disclosure of data to a wide audience. It requires the establishment of representation systems based on the development of virtual environments.

scholarly journals Sustainability and Depletion Accounting: A Case Study of Oil in Libya

2017 ◽  
Vol 7 (1) ◽  
pp. 34 ◽  
Author(s):  
Abdulrazag Mohamed Etelawi ◽  
Keith A. Blatner ◽  
Jill McCluskey
Keyword(s):  
Sustainable Development ◽  
Planning Process ◽  
National Income ◽  
Policy Makers ◽  
The Sustainable Development ◽  
Time Period ◽  
Oil Resources ◽  
Income Development ◽  
Per Capita ◽  
High Level

There is a strong need to study sustainability and depletion accounting of oil in the Libyan economy because oil production and export is the single largest source of national income in the country. This study covers the time period from 1990 to 2009. Throughout this period, the Libyan national economy used its oil and petroleum industries to increase national income. Development sustainability can be defined as investment divided by GDP. This measure provides an indication of the low level of sustainable development in Libya over the period of analysis, which is 0.38 on average. It is important that the Libyan government develop and implement plans and strategies for achieving sustainability and the maintenance of oil resources.Carbon dioxide emissions provide another indication of the presence or absence of sustainability. The ratio of carbon dioxide ranged from a minimum of 8.50 metric tons per capita in 1990 to 10.00 metric tons per capita in 2009 and average 9.07 metric tons per capita over the course of the study period. CO2 emissions were also much higher than other countries in the Middle East and North Africa. This suggests there was relatively little interest in the sustainable development of the Libyan economy during this period. The Environment Domestic Product (EDP) increased sharply from the beginning of the study at $24.23 billion in 1991 to $45.87 billion in 2009 in constant dollars. Again, one can infer that policy makers did not consider the depletion of oil resources and the environment in their planning process, or at least did not place a high level of concern on this issue.

scholarly journals The Role of State in Achieving Sustainable Development Goals in Slovenia

2020 ◽  
Vol 29 (4) ◽  
pp. 233
Author(s):  
Senko Plicanic
Keyword(s):  
Sustainable Development ◽  
Sustainable Development Goals ◽  
Active Role ◽  
The State ◽  
The Sustainable Development ◽  
Role Of The State ◽  
Starting Point ◽  
Development Goals ◽  
State And Local

<p>The article analyses the importance of an active role of the state in achieving the Sustainable Development Goals. Its starting point is that despite the fact that today there is a growing recognition in the world that for the implementation of sustainable development an active role of the state and local self-governing communities is indispensable and despite the fact that in Slovenia such a role of the state in implementing sustainable development stems from its Constitution, so far, too little has been done in Slovenia to achieve the Sustainable Development Goals. The purpose of this article is to analyse theoretical arguments and the Constitution in order to show the need for an active role of the state in implementing sustainable development goals, and also to discuss basic steps to be implemented in order to achieve an active role of the state in Slovenia. In this article comparative and analytical methods were used in studying the literature and regulation. The article, based on theoretical arguments and the constitutional analysis, identifies the need for an active role of the state in implementing sustainable development goals, and proposes arguments for it and also basic steps toward an active role of the state. The discussed topic is new and this article contributes to the field some fundamental arguments for the active role of state and for the more comprehensive policy-making. The article offers theoretical and constitutional arguments to be implemented in order to transform the present role of the state from a passive one into an active role and its findings are meant to be used by policy-makers and law-makers as a significant argument to pursue more active role of the state in implementing sustainable development goals.</p>

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