scholarly journals Chlamydia trachomatis and Neisseria gonorrhoea Co-Infection Among Patients Attending a Teaching Hospital in Nairobi County: A Retrospective Study

2021 ◽  
Vol 3 (1) ◽  
pp. 51-57
Author(s):  
Festus Mulakoli

Background: Chlamydia trachomatis and Neisseria gonorrhoea are microbes that have been associated with urethritis in both male and female genders, which often may lead to complicated conditions such as pelvic inflammatory disease (PID) and infertility globally among others health complications. In Kenya and other developing countries, sexually transmitted infections associated with Chlamydia trachomatis and Neisseria gonorrhoea still pose a challenge in public health. Methods: A retrospective study was conducted by reviewing laboratory data from Jan 2018 to Dec 2018 to estimate the prevalence of C trachomatis and N gonorrhoea coinfections in patients attending a tertiary institution and its satellite clinics spread across the country. A total of 1228 patient’s data aged 3-69 years was reviewed; with age, gender and Chlamydia trachomatis and Neisseria gonorrhoea status being analyzed. Results: A total of 1228 patients who visited the hospital in 2018 had their urine samples being tested for Chlamydia trachomatis and Neisseria gonorrhoea by use of a PCR technique. Majority of the patients were males (63.7%). The patients who tested for Chlamydia trachomatis and Neisseria gonorrhoea had an average age of 34 years (range: 3–69 years). Of those 1.4% tested positive for both Chlamydia trachomatis and Neisseria gonorrhoea infections, and males were more infected than females (1.1% vs 0.3). From the information gathered during the study period, the proportion of patients with Chlamydia trachomatis infection was (16.1 %) (95 % CI 9.5, 17.9), and with N. gonorrhoea infection was 5.4%. Coinfection was highest among sexually active group that is those aged between 21 years to 40 years. Conclusion: The prevalence of C. trachomatis is significantly high among male patients. We recommend the implement a molecular screening for Chlamydia trachomatis and Neisseria gonorrhoea to identifying asymptomatic female cases. This study further provides evidence on the importance of contact tracing in the management of Chlamydia trachomatis and other STIs. There is an urgent need for studies designed to investigate the prevalence and risk factors of Chlamydia trachomatis and Neisseria gonorrhoea among female patients who are majorly asymptomatic in Kenya.

2013 ◽  
Vol 88 (4) ◽  
pp. 523-529 ◽  
Author(s):  
Luiz Jorge Fagundes ◽  
Elso Elias Vieira Junior ◽  
Ana Carolina Marteline Cavalcante Moysés ◽  
Fernão Dias de Lima ◽  
Fátima Regina Borges de Morais ◽  
...  

BACKGROUND: Sexually Transmitted Diseases are still considered a serious public health problem in Brazil and worldwide.OBJECTIVE: To examine Sexually Transmitted Diseases prevalence and the sickness impact profile of STDs in a reference health center specializing in the treatment of Sexually Transmitted Diseases.METHOD: We collected epidemiological, demographic, clinical and laboratory data from the medical records and interviews of 4,128 patients who had attended the center from January 1999 to December 2009.RESULTS: Male patients outnumbered (76%) females (24%), Caucasians outnumbered (74.3%) those of mixed race (14.8%), blacks (10.8%) and Asians (0.1%). STD occurrence was higher in the 20-29 age group (46.2%) This population included 34.7% high school graduates, 8.7% college graduates and 0.8% illiterates. As for affective-sexual orientation, 86.5% were heterosexual, 7.8% homosexual and 5.5% bisexual. Regarding patients' sexual practices over the previous 30 days, 67.7% reported sexual intercourse with one person, 8.6% had had sex with two persons and 3.9%, with three or more people. The highest incidence of STD was condyloma acuminata, affecting 29.4% of all the patients, genital candidiasis 14.2%, and genital herpes 10.6%. Of the 44.3% who submitted to serologic testing for HIV detection 5% were positive, with a ratio of 6.8 males to 1 female.CONCLUSIONS:STD prevalence remains high in Brazil and it is necessary to invest in early detection, prevention and treatment.


2018 ◽  
Vol 30 (4) ◽  
pp. 336-343
Author(s):  
Danielle AP Rocha ◽  
Cássia de Oliveira Moraes ◽  
Adriene F Araújo ◽  
Êmille dos Santos Beltrão ◽  
Lainara Castelo dos Santos ◽  
...  

Chlamydia trachomatis infection is the most common sexually transmitted bacterial infection among women. In Brazil, there is no organized screening program for C. trachomatis, and the actual prevalence of infection is unknown. This study aimed to determine the prevalence of C. trachomatis infection in women living in riverside communities in the Amazon, using self-collection employing the Evalyn® Brush and polymerase chain reaction. A total of 299 riverine women aged 18–81 years, mean age 35.7 (±12.8) years, predominantly agricultural workers, with low schooling and living with a partner, participated in this study. The prevalence of C. trachomatis infection was found to be 3.7% (95% CI 1.8–6.5), most of them being symptomatic. The mean age of the first sexual intercourse reported by women was 15.2 (±2.3) years, and the majority reported having had none or only one partner in the last 12 months, with very low adherence to consistent condom use (15.4%). Most women (98.3%) reported having approved using the vaginal self-collecting brush, and only 4.7% reported having difficulty in handling the brush. We consider that a vaginal self-collecting device is adequate for diagnosing C. trachomatis infection in women living in remote, hard-to-reach areas.


2011 ◽  
Vol 2 (1) ◽  
pp. 14 ◽  
Author(s):  
Tommaso Cai ◽  
Sandra Mazzoli ◽  
Nicola Mondaini ◽  
Gianni Malossini ◽  
Riccardo Bartoletti

<p>The role of <em>Chlamydia trachomatis</em> (Ct) in everyday clinical practice is now on the increase because Ct infections are the most prevalent sexually transmitted bacterial infections worldwide. Ct can cause urethritis, cervicitis, pharyngitis, or epididymitis, although asymptomatic infections are quite common. Ct infection remains asymptomatic in approximately 50% of infected men and 70% of infected women, with risk for reproductive tract sequelae both in women and men. A proper early diagnosis and treatment is essential in order to prevent persistent consequences. An accurate comprehension of the pathology, diagnosis and treatment of this entity is essential for the urologist. We review the literature about the new findings in diagnosis and treatment of Ct infection in sexually active young men.</p>


2022 ◽  
Vol 15 (1) ◽  
pp. e246494
Author(s):  
Robin Shepherd ◽  
Alexandra Crossland ◽  
Rafal Turo ◽  
Michelle Christodoulidou

We describe an unusual case of a male patient presenting with penile and testicular swelling following an unprotected and traumatic sexual encounter. It was suspected that an isolated penile injury occurred during intercourse; however, ultrasound imaging identified an intact tunical layer and right-sided epididymo-orchitis. Following screening for sexually transmitted infections (STIs), he was discharged with antibiotics and advice to attend the Sexual Health Centre for contact tracing. He represented with a periurethral abscess and an antimicrobial-resistant (AMR) strain of Neisseria gonorrhoea was identified. Appropriate antibiotic treatment was initiated. Examination-under-anaesthesia, following abscess drainage, revealed a contained collection with no urethral fistula; however, a flat urethral lesion was seen during urethroscopy. Repeat urethroscopy and biopsy of the lesion indicated polypoid urethritis. Periurethral abscess secondary to gonococcal urethritis is a rare complication, but one that we should be suspicious of, especially with the growing incidence of AMR-STIs.


2018 ◽  
Vol 36 (06) ◽  
pp. 340-350 ◽  
Author(s):  
Christine Nadeau ◽  
Dennis Fujii ◽  
Jessica Lentscher ◽  
Amanda Haney ◽  
Richard Burney

Abstract Chlamydia trachomatis is the most common sexually transmitted bacterial infection in the United States. Within the U.S. military, the age- and race-adjusted chlamydia infection rates among female service members are consistently higher than civilian rates, with a 20% annual acquisition rate among young active-duty women. The sequelae of chlamydia disproportionately impact women in terms of severity and cost. Untreated chlamydia progresses to pelvic inflammatory disease in 40% of cases, and is a leading cause of fallopian tube damage and pelvic adhesive disease resulting in ectopic pregnancy, tubal infertility, and acute and chronic pelvic pain. Tubal infertility is among the leading indications for in vitro fertilization (IVF) nationally and rates among couples undergoing IVF at military treatment centers are double the national average. Collectively, chlamydia infection represents a significant resource burden to the military health care system and, in view of the serious gynecologic health sequelae, a significant threat to the readiness of servicewomen. In this review, we discuss the gynecologic impact of chlamydia infection within the military, the critical gaps for research funding, and opportunities for intervention.


Sexual Health ◽  
2005 ◽  
Vol 2 (1) ◽  
pp. 23 ◽  
Author(s):  
A. R. Markos

Introduction: The rate of transmission of Chlamydia trachomatis, by infected males and females to their sexual partners, has been a matter of continued scientific interest and exploration. Methods: We examined the correlation of C. trachomatis infection in sexual partnerships, using Strand Displacement Amplification. Results: During July–November 2003, 97 male patients were reported positive for C. trachomatis. Fifty of the female sexual consorts were amenable for contact tracing, 38 of whom were identified as C. trachomatis positive. Within the same period, 93 female patients were C. trachomatis positive, and 56 male consorts were traceable, of whom 43 were positive for C. trachomatis. Conclusions: The concordance of C. trachomatis between sexual partners is in the region of 75%. This strengthens the case for epidemiological treatment for all consorts.


2019 ◽  
Author(s):  
Albert Njeru ◽  
Joseph Mwafaida

AbstractBackgroundChlamydia and candidiasis have only mild or no symptoms at all. When symptoms develop, they are often mistaken for something else like urinary tract infections or yeast infections. These infections affect both men and woman of all backgrounds and economic levels.ObjectiveThe prevalence of Chlamydia trachomatis (C.trachomatis) and Candida albicans (C.albicans) infections among attendees of Kilifi Medical Centre in Kilifi county, Kenya was studied.MethodologyUrethral and vaginal swabs samples were aseptically collected from 305 subjects, examined for Candida albicans and Chlamydia trachomatis using standard microbiological methods. The swabs were analyzed using direct wet smears, Gram-stained smear and culture techniques.ResultsOf the 305 participants, 181 (59.34%) females and 124 (40.66%) males were tested with the overall prevalence of 53.44 % for both Chlamydia trachomatis and Candida albicans with females having a higher infection rate (35.14 %) for chlamydia and candidasis than men (17.71). Amongst the different age groups investigated, candida and chlamydia distribution was highest in participants aged 28-32 years (21.97 %).The infection rate of C.trachomatis (14.43 %) among the male participants was higher than the infection rate revealed among the female participants of 1.97 % while the infection rate of C.albicans was higher among the female participants (33.77 %) compared to the 3.28 % recorded in male participants with no co-infections revealed.ConclusionThe results of this study demonstrated a significant difference between male and female chlamydia and candida infections with women being severely affected than men. The study recommended routine screening for sexually transmitted infections (STIs) which is essential in preventing infections transmissions, assessment of the role of socio-demographic and behavioral risks on Chlamydia trachomatis and Candida albicans, proper treatment of all candida and chlamydia by use of correct/effective medicines, contact tracing and treatment of sexual partners and health education.


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