scholarly journals Investigation of risk factors associated with infections caused by small ruminant lentiviruses

2013 ◽  
Vol 57 (4) ◽  
pp. 473-478 ◽  
Author(s):  
Nuria Barquero ◽  
Esperanza Gomez-Lucia ◽  
Alvaro Arjona ◽  
Cristina Toural ◽  
Alfonso Las Heras ◽  
...  
Keyword(s):  
Risk Factors ◽  
Central Region ◽  
Small Ruminant ◽  
Multivariable Analysis ◽  
Geographical Location ◽  
Infected Sheep ◽  
Statistical Relationship ◽  
Factors Associated ◽  
The Relationship ◽  
Lambing Rate

Abstract An epidemiological study was conducted to identify risk factors related to small ruminant lentivirus (SRLV) infection in the central region of Spain. Between October 1998 and October 2000, a total of 194 sheep from 10 flocks and 163 goats from three flocks were tested for SRLV antibodies, resulting in 65.5% and 8.0% of seroprevalence, respectively. The relationship between differences in prevalence of SRLV, geographical location of the flock, and possible factors related to the flock that could enhance transmission were studied. Results of multivariable analysis showed an association between SRLV infection and geographical location of the flock and the rearing system. In addition, the differences in the productivity between infected and non-infected animals were explored. The productivity parameters were measured in 62 sheep and 28 goats. All productivity parameters studied (milk production, number of milking days, and lambing rate) appeared to be reduced in the SRLV-seropositive group in both goats and sheep. Even though, these differences were not statistically significant, it seems that animals infected are less productive than these non-infected. Statistical analyses comparing infected and non-infected sheep showed no statistical relationship between SRLV infection and milk quality.

scholarly journals Multivariable analysis to determine risk factors associated with early pregnancy loss in thoroughbred broodmares

2019 ◽  
Vol 124 ◽  
pp. 18-23 ◽  
Author(s):  
A.M. de Mestre ◽  
B.V. Rose ◽  
Y.M. Chang ◽  
D.C. Wathes ◽  
K.L.P. Verheyen
Keyword(s):  
Risk Factors ◽  
Early Pregnancy ◽  
Pregnancy Loss ◽  
Multivariable Analysis ◽  
Early Pregnancy Loss ◽  
Factors Associated

P0034IDENTIFICATION OF FACTORS ASSOCIATED WITH PROGRESSION, PROGNOSIS AND TOLVAPTAN INDICATION IN POLYCYSTIC KIDNEY DISEASE PATIENTS

2020 ◽  
Vol 35 (Supplement_3) ◽  
Author(s):  
Myrto Kostopoulou ◽  
Michaela Louka ◽  
Stavros Fokas ◽  
Eirini Tigka ◽  
Angelos Drakopoulos ◽  
...  
Keyword(s):  
Risk Factors ◽  
Kidney Disease ◽  
Polycystic Kidney Disease ◽  
Multivariable Analysis ◽  
Laboratory Data ◽  
Kidney Volume ◽  
Polycystic Kidney ◽  
Factors Associated ◽  
Affected Parent ◽  
Male Sex

Abstract Background and Aims The identification of possible risk factors for the progression of Autosomal Dominant Polycystic Kidney Disease (ADPKD) is an emerging field especially after the introduction of the first disease-specific treatment. The present study aims to explore the associations between epidemiological, clinical and imagining data in a large cohort of ADPKD patients. Method This study was from a single outpatient clinic following patients with ADPKD. Patients were included in the study if they had a recent Magnetic Resonance Imaging (MRI) for measurement of Total Kidney Volume (TKV), a validated biomarker for disease progression. For all patients, the Mayo Clinic Imagining Category (MCIC) and the respective prediction for End Stage Renal Disease (ESRD) were calculated. Patients eligible for tolvaptan treatment (MCIC 1C, 1D, 1E, age < 55 years old and estimated-glomerular filtration rate (e-GFR) ≥ 25 ml/min) were identified. Characteristics including individual medical history, clinical and laboratory data were examined for possible associations with renal and imagining parameters using linear regression models. Results A total of 158 patients were included. Based on measurements of height-adjusted TKV (ht-TKV) and age, 5% of the patients were classified as 1A, 20% as 1B, 34% as 1C, 25% as 1D and 16% as 1E, MCIC. In multivariable analysis, patient’s age (p = 0.01), male sex (p < 0.001), parent’s age at which ESRD was reached (adjusted for patient age) (p < 0.001) and proteinuria (p = 0.04) were associated with ht-TKV. Parent’s age at ESRD differed significantly between the MCICs of the offspring (mean±(SD)), 70.83 (12.90) in 1A, 63.79 (11.39) in 1B, 57.32 (10.42) in 1C, 51.42 (9.18) in 1D and 47.94 (5.73) years old in 1E, (p < 0.001). Similarly, there were significant differences in the presence and the age of hypertension onset (p =0.004 and p = 0.003, respectively). In 104 patients (50 females, 54 males) who were eligible for tolvaptan treatment age at ADPKD diagnosis, age at hypertension onset and parent’s age reaching at ESRD were all significantly lower (p < 0.001 for all) when compared to non-eligible patients. Finally, factors associated with the prediction score of ESRD (e-GFR 10/ml/min) were hypertension, uric acid and the age at ESRD of the affected parent (p = 0.001, 0.02 and 0.01, respectively). Conclusion The age at which an affected parent had reached ESRD, as heritability estimator, was significantly associated with a worst phenotype, prognosis and tolvaptan indication. Early diagnosis of the disease, hypertension and its early onset, proteinuria and male sex are also possible risk factors for the progression of ADPKD.

Young Offenders in Custody: Risk and Adjustment

2005 ◽  
Vol 32 (3) ◽  
pp. 251-277 ◽  
Author(s):  
Carla Cesaroni ◽  
Michele Peterson-Badali
Keyword(s):  
Risk Factors ◽  
Psychosocial Functioning ◽  
Young Person ◽  
Young Offenders ◽  
Factors Associated ◽  
Institutional Risk ◽  
The Relationship

This article explored results from a study of 113 incarcerated male youths, who were age 12 to 15 at the time of their indexed offense. Using a widely used, normed measure of psychosocial functioning, the study examined the relationship between preexisting risk factors and/or institutional risk factors and adjustment in custody. Preexisting risk or vulnerability significantly predicted adjustment to custody, as did several risk factors within facilities (worry about victimization, perceiving victimization as likely, and experiencing conflicts with inmates as difficult). Risk factors associated with institutional life appeared to contribute to a young person’s adjustment beyond the risk factors a young person may walk into an institution with. One commonly used measure of institutional functioning, number of custodial rule infractions, did not appear to be a valid indicator of how a youth felt or adjusted to a facility. Limitations and implications of the findings are discussed.

scholarly journals Child Maltreatment Among Singletons and Multiple Births in Japan: A Population-Based Study

2015 ◽  
Vol 18 (6) ◽  
pp. 806-811 ◽  
Author(s):  
Yoshie Yokoyama ◽  
Terumi Oda ◽  
Noriyo Nagai ◽  
Masako Sugimoto ◽  
Kenji Mizukami
Keyword(s):  
Risk Factors ◽  
Risk Factor ◽  
Child Maltreatment ◽  
Personal Information ◽  
Population Based ◽  
Multiple Births ◽  
Population Based Study ◽  
Factors Associated ◽  
Increased Risk ◽  
The Relationship

Background: The occurrence of multiple births has been recognized as a risk factor for child maltreatment. However, few population-based studies have examined the relationship between multiple births and child maltreatment. This study aimed to evaluate the degree of risk of child maltreatment among singletons and multiple births in Japan and to identify factors associated with increased risk. Methods: Using population-based data, we analyzed the database of records on child maltreatment and medical checkups for infants aged 1.5 years filed at Nishinomiya City Public Health Center between April 2007 and March 2011. To protect personal information, the data were transferred to anonymized electronic files for analysis. Results: After adjusting by logistic regression for each associated factor and gestation number, multiples themselves were not associated with the risk of child maltreatment. However, compared with singletons, multiples had a significantly higher rate of risk factors for child maltreatment, including low birth weight and neural abnormality. Moreover, compared with mothers of singleton, mothers of twins had a significantly higher rate of poor health, which is a risk factor of child maltreatment. Conclusion: Multiples were not associated with the risk of child maltreatment. However, compared with singletons, multiples and their mothers had a significantly higher rate of risk factors of child maltreatment.

scholarly journals Parental risk factors associated with congenital heart disease in a Thai population: multivariable analysis

2021 ◽  
Vol 15 (6) ◽  
pp. 267-276 ◽  
Author(s):  
Chayamon Suwansumrit ◽  
Worawan Jittham
Keyword(s):  
Risk Factors ◽  
Family History ◽  
Cigarette Smoke ◽  
Congenital Heart ◽  
Heart Diseases ◽  
Multivariable Analysis ◽  
Significant Risk ◽  
Maternal Exposure ◽  
Factors Associated ◽  
History Of

Abstract Background Congenital heart diseases (CHDs) are the most common types of birth defects and contribute to a large proportion of infant morbidities and mortalities worldwide. These defects may require multiple surgical interventions impacting the infant's quality of life. Objectives To identify risk factors associated with CHD in a population of Thai children. Methods We conducted a case–control study of patients attending the Pediatric Clinic, Naresuan University Hospital, Thailand. We included data from pediatric patients diagnosed with CHDs as cases, and patients without cardiovascular abnormalities as controls. Risk data were collected from July 2019 to April 2020 using face-to-face interviews. Multiple logistic regression was used to analyze parental factors associated with CHDs. Results We included 249 cases classified into 2 groups according to severity and 304 patients as controls. For those less-severely affected (155 patients, 62.2%), ventricular septal defect (27.7%) was the most prevalent, whereas for those with severe CHDs, tetralogy of Fallot was the most prevalent (14.0%). There was no difference in sex distribution or maternal obstetric history between the groups. In multivariable analysis, a family history of CHDs (adjusted odds ratio [AOR] 4.67, 95% confidence interval (CI) 1.61–13.57, P = 0.005) and maternal exposure to second-hand cigarette smoke (AOR 1.58, 95% CI 1.03–2.42, P = 0.002) were identified as significant risk factors for CHDs. Conclusion A family history of CHDs and maternal exposure to second-hand cigarette smoke are associated with having offspring with CHDs in the population studied. These findings help us to encourage affected parents to obtain a fetal echocardiogram.

scholarly journals Risk Factors of Going Missing in People Living With Dementia: A Scoping Review

2021 ◽  
Vol 5 (Supplement_1) ◽  
pp. 643-644
Author(s):  
Noelannah Neubauer ◽  
Hector Perez ◽  
Antonio Miguel-Cruz ◽  
Christine Daum ◽  
Samantha Dawn Marshall ◽  
...  
Keyword(s):  
Risk Factors ◽  
Physical Environment ◽  
Geographical Location ◽  
Adverse Outcomes ◽  
Factors Associated ◽  
Care Partners ◽  
Scoping Reviews ◽  
Support Resources ◽  
Different Types

Abstract Critical wandering is common in persons living with dementia, it is defined as wandering that results in an individual going missing. This exposes the missing vulnerable older adult to risks and dangers. Persons with dementia who become lost and go missing and get lost can face adverse outcomes, such as injury and death, yet the amount of information available on the risk factors associated with these incidents is scarce. The aim of this study was to identify the risk factors associated with critical wandering in persons living with dementia. We used Tricco et al.’s (2018) approach for scoping reviews and searched the following databases: Medline, EMBASE, CINAHL, and Scopus. We included studies that referred to critical wandering in persons with dementia, cognitive impairment, or Alzheimer, and published since 1980. We identified 3,376 publications, which was reduced to 1641 publications after we removed duplications. A total of 78 studies met the inclusion and exclusion criteria for analysis and extraction. A rigorous process to synthesize and categorize the research evidence was followed. We identified four different types of risk factors associated with going missing: (1) personal, (2) physical environment and geographical location, (3) cultural environment, and (4) social environment and support resources. Recognition of these risk factors can help persons living with dementia and their care partners identify interventions and proactive strategies to mitigate or prevent critical wandering. This will support persons with dementia, their care partners, and community organizations to balance safety, autonomy, and independence to maximize quality of life.

scholarly journals The clinical importance of microscopic hematuria and hydronephrosis in urolithiasis

2021 ◽  
Author(s):  
Kamil Kokulu ◽  
ekrem taha sert
Keyword(s):  
Risk Factors ◽  
Odds Ratio ◽  
Clinical Importance ◽  
Microscopic Hematuria ◽  
Ureteral Stones ◽  
Stone Size ◽  
Factors Associated ◽  
Radiology Reports ◽  
Contrast Ct ◽  
The Relationship

Aim: The aim of this study was to investigate the relationship between the degree of hydronephrosis and the presence of microscopic hematuria in patients that presented to the emergency department (ED) with ureteral stones. Methods: The records of patients who presented to our ED due to urolithiasis between January 2017 and December 2020 were retrospectively analyzed. Patients aged 18 years or older who underwent non-contrast computed tomography (CT abdomen/pelvis) and urinalysis (UA) and were diagnosed with ureteral stones were included in the study. Radiology reports were reviewed for stone size, localization, and degree of hydronephrosis. Patients with and without microscopic hematuria and the degree of hydronephrosis were compared. Results: A total of 476 patients were included, which consisted of 391 with microscopic hematuria and 85 without microscopic hematuria. The median stone size was 4.1 mm in the presence of microscopic hematuria and 5.5 mm in the absence of microscopic hematuria. Logistic regression analysis was performed to determine the factors associated with the development of hydronephrosis. Stone size [odds ratio (OR):2.15, 95% confidence interval (CI):1.12-4.16, p<0.001), presence of pyuria (OR: 2.58, 95%CI: 1.78-3.48, p<0.001), and absence of microscopic hematuria (OR: 1.31, 95%CI 1.04-2.89, p=0.017) were identified as risk factors for moderate and severe hydronephrosis. Conclusion: We consider that non-contrast CT imaging is necessary for the diagnosis and treatment of emergency cases in which microscopic hematuria is not detected in urinalysis since their stone size may be larger and degree of hydronephrosis may be more severe.

Investigation of Risk Factors Associated with Atmospheric Pollution on the Spread of COVID-19 Using Open Data from the Internet: Italy as an Example (Preprint)

2020 ◽  
Author(s):  
Li-Wei Chen ◽  
Po-Hsun Cheng ◽  
Hsien-Da Lee ◽  
Tin-Kai Chen
Keyword(s):  
Risk Factors ◽  
Statistical Methods ◽  
Atmospheric Pollution ◽  
Fine Particulate Matter ◽  
Open Data ◽  
Blood Stream ◽  
Time Shift ◽  
Factors Associated ◽  
The Relationship ◽  
Pm2.5 Concentration

BACKGROUND As coronavirus disease 2019 (COVID-19) rapidly spreads worldwide, some attention has focused on studying the relationship between atmospheric pollution and the disease. Fine particulate matter with a diameter of 2.5 μm or less (PM2.5) is the most harmful form of atmospheric pollution because it can penetrate deep into the lungs and enter the blood stream unfiltered. OBJECTIVE To investigate the effects of risk factors associated with atmospheric pollution on the spread of COVID-19, taking Italy as an example. METHODS For descriptive statistical methods, the statistics of minimum, maximum, mean, median, standard deviation, rank, mean rank, and rank summation as well as time-series charts were used to depict the profiles of the relations among these input and output variables. For inferential statistical methods, Mann-Whitney U tests and Pearson, Kendall, and Spearman correlation tests were introduced to obtain more reliable conclusions regarding the study topic. RESULTS Statistical analysis showed that higher PM2.5 concentration and an industrial orientation may increase the spread of COVID-19. Moreover, 3-week time-shift and nonlinear relations may be optimal for use with PM2.5 concentration for predicting the spread of COVID-19. CONCLUSIONS Our results empirically proved that certain risk factors associated with atmospheric pollution (such as PM2.5 concentration and industrial orientation) affect the spread of COVID-19. In future analyses, additional factors that may affect the outcomes of COVID-19 as well as data from other countries will be included to obtain more complete conclusions. CLINICALTRIAL None.

Risk factors associated with early postoperative complications following laparoscopic total gastrectomy: Experience from the Chinese Laparoscopic Gastrointestinal Surgery Study (CLASS) group.

2017 ◽  
Vol 35 (15_suppl) ◽  
pp. e15544-e15544
Author(s):  
Jingdong Liu ◽  
Haojie Li ◽  
Gang Zhao ◽  
Zekuan Xu ◽  
Guoxin Li ◽  
...  
Keyword(s):  
Risk Factors ◽  
Gastric Cancer ◽  
Postoperative Complications ◽  
Total Gastrectomy ◽  
Multivariable Analysis ◽  
Laparoscopic Total Gastrectomy ◽  
Morbidity And Mortality ◽  
Reconstruction Method ◽  
Factors Associated ◽  
Early Postoperative Complications

e15544 Background: The incidence rate of proximal gastric cancer has been rising steadily, and laparoscopic total gastrectomy (LTG) has been widely adopted. However, the safety of LTG still lacks solid evidence to prove. The aim of this study was to evaluate morbidity and mortality of LTG, and determine the risk factors associated with early postoperative complications. Methods: A retrospective multicenter study was carried out in China, and medical records of 109 gastric cancer patients receiving LTG during September 2014 and June 2016 were retrieved from the database. Patient characteristics, surgical outcomes, and postoperative morbidities and mortalities were analyzed. Results: Morbidity and mortality rates were 22.0% and 0% respectively. Pulmonary infection (13.8%, n = 15) was the most common complication. Most complications were grade II (15.5%, n = 17) according to the Clavien-Dindo classification. Multivariable analysis identified comorbidity, type of reconstruction method (TLTG) were independent risk factors of early postoperative complications. Comorbidity was the only independent risk factor of complications graded more than II. Diabetes mellitus was found correlated with surgical complication in subgroup analysis. Conclusions: LTG is safe and technically feasible in treating gastric cancer. Careful selection of patients without comorbidity and applying laparoscopy-assisted total gastrectomy instead of totally laparoscopic total gastrectomy may decrease postoperative complications.

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