scholarly journals Age-Related Changes in the Gross Morphology and Morphometry of the Testis and Epididymis of the African Greater Cane Rat (Thryonomys swinderianus)

Author(s):  
Jamiu Oyewole Omirinde ◽  
Samuel Gbadebo Olukole ◽  
Bankole Olusiji Oke

This study evaluated age-related changes in the gross morphology and morphometry of the testis and epididymis of the African Greater Cane Rat (AGCR). Twenty pathogen-free cane rats used for this study were randomly divided into 4 groups; Group I - prepubertal (≤4 months), Group II - pubertal (>4≤12 months), Group III - adult (>12≤30 months), and Group IV - aged (>30 months) of 5 animals each. On day 8th of acclimatization, testis and epididymis were harvested from sedated cane rat, described grossly and standard morphometric parameters (length, width, circumference, weight, and relative weight) determined. Gross morphological observations in the testes of all the different age categories showed similar characteristically cream to milky-white coloration and ellipsoidal shape. The epididymis in the different AGCR group uniquely presents the same inverted S-shaped outline, loose attachment to the testis, and less distinct division into caput, corpus, and cauda segments. Testicular and epididymal morphometric parameters were significantly reduced in the prepubertal cane rat relative to other groups. The parameters consistently displayed an age-dependent increment with the advancing age of the animal. In conclusion, this study has shown that both testicular and epididymal gross morphometrics increase with age advancement and perhaps might be linked to the varying functional reproductive status of the different age groups of the African greater cane rat.

Author(s):  
Shailendra Chaurasia ◽  
R. Menaka ◽  
Thakur Krishna Shankar Rao ◽  
K.K. Tyagi

A study was conducted to elucidate the topographic location and morphometry of the spleen in 30 Surti goat foetuses at different stages of their development ranging from 44 to 144 days (4.0 to 41.0 cm CRL). On the basis of CR length, the foetuses were divided into three age groups viz., group-I (4.0 to 11.6 cm CRL), group-II (12.2 to 26.8 cm CRL) and group-III (27.2 to 41.0 cm CRL). Special attempt has been made to fit prediction equation (stepwise regression) for estimation of approximate age of Surti goat foetuses by using splenic biometrics. The developing spleen was observed at the age of 44 days (4.0 cm CRL) in abdominal cavity close to the stomach. The shape of spleen was roughly quadrilateral in all age groups. The various spleen measurements viz., length, width, thickness, volume and weight increases in dimensions during different stages of development and all the changes were highly significant (P less than 0.01). The mean relative weight of spleen was maximum (0.15%) in group-III. Among splenic parameters, the length of spleen was found most important variable; which could be used for estimation of age using stepwise regression (R2 = 0.97) model in Surti goat foetuses.


2021 ◽  
Vol 5 (1) ◽  
pp. 026-031
Author(s):  
A Bello ◽  
HH Wamakko

This research was conducted over period of 3 months with the aim of studying Age related changes of selected bones of forelimb (Scapula, Humerus, Radius and Ulna) in Local Mongrelian Dog (Canis lupus familiaris). The study entails biometrical and gross observations on the bones. The sample bones were acquired from the experimental animals of comparative anatomy in the department. The bones were categorized into various age groups for the research. The length, width, diameter and circumference of the samples (scapula, humerus, radius and ulna bones) were determined for all the groups. The shape, size, color, location, position and relation of each segment of the samples at various stages of development were determined. The differences across the age groups of different samples were observed and recorded. Based on the research result, it was concluded that, the biometric and morphometry data was found to be increasing with advancement of age. A baseline data was established with the view to enhance learning.


Author(s):  
Vishnudeo Kumar ◽  
Anil Sharma

A study was conducted on the adrenal gland of 20 Gohilwadi goats (Capra hircus), age ranging from day old to adult. Animals were divided in three age groups, viz., group-I (day old to 1 month), group-II (1 to 6 months) and group-III (above 6 months). The different gross and biometric parameters, viz., weight, length, width and thickness of both left and right adrenal gland were recorded. The left adrenal gland was roughly oval elongated and right was roughly triangular in shape in all the age groups. Different biometric parameters of adrenal gland increased significantly (P less than 0.05) from group I to group III. There was no significant difference (P>0.05) in various gross and biometric observations between left and right adrenal gland within the same group.


Author(s):  
Ahmed Mousa ◽  
Ossama M. Zakaria ◽  
Mai A. Elkalla ◽  
Lotfy A. Abdelsattar ◽  
Hamad Al-Game'a

AbstractThis study was aimed to evaluate different management modalities for peripheral vascular trauma in children, with the aid of the Mangled Extremity Severity Score (MESS). A single-center retrospective analysis took place between 2010 and 2017 at University Hospitals, having emergencies and critical care centers. Different types of vascular repair were adopted by skillful vascular experts and highly trained pediatric surgeons. Patients were divided into three different age groups. Group I included those children between 5 and 10 years; group II involved pediatrics between 11 and 15 years; while children between 16 and 21 years participated in group III. We recruited 183 children with peripheral vascular injuries. They were 87% males and 13% females, with the mean age of 14.72 ± 04. Arteriorrhaphy was performed in 32%; end-to-end anastomosis and natural vein graft were adopted in 40.5 and 49%, respectively. On the other hand, 10.5% underwent bypass surgery. The age groups I and II are highly susceptible to penetrating trauma (p = 0.001), while patients with an extreme age (i.e., group III) are more susceptible to blunt injury (p = 0.001). The MESS has a significant correlation to both age groups I and II (p = 0.001). Vein patch angioplasty and end-to-end primary repair should be adopted as the main treatment options for the repair of extremity vascular injuries in children. Moreover, other treatment modalities, such as repair with autologous vein graft/bypass surgery, may be adopted whenever possible. They are cost-effective, reliable, and simple techniques with fewer postoperative complication, especially in poor/limited resources.


Author(s):  
A. Prasanth Babu ◽  
P. Jagapathi Ramayya ◽  
Y. Nagamalleswari ◽  
Makkena Sreenu ◽  
K. Lakshmi Kavitha

Background: Affections of eye commonly encountered in all the species of animals. If these not treated in time, the vision may be hampered, this may impair the physical ability, utility and productivity of animals leading to economic loss to the animal owners. Corneal dystrophies like basement membrane dystrophy, stromal dystrophy, endothelial dystrophy, corneal erosions and corneal ulcerations etc., seen in the aged buffaloes. The current study was carried out to establish basic data and to provide authentic information to the clinicians on ageing changes in eyes of buffaloes.Methods: The study on age related changes in the cornea was conducted on 63 eye balls of locally available buffaloes of different breeds in and around Proddatur. These buffaloes were categorized into 3 groups based on their age i.e., group I (1-5 yrs), group II (6-10 yrs) and group III (11 yrs and above) buffaloes. The eyeballs were isolated and fixed with Davidson’s fluid. The paraffin sections of cornea were subjected for routine histological study.Result: The mean total thickness (µm) of cornea was increased from group I to III animals and it was 747.22±13.57, 853.33±11.05 and 897.22±8.06. Hence, The mean thickness (µm) of all five layers of cornea increased with advancement of age. Superficial corneal epithelial layer was made up of non keratinized stratified squamous epithelium with 6 to 7 layers at early age and 12-14 layers of cells in adult animals. The mean thickness (µm) of corneal epithelium in group I to III animals was 117.04±3.37, 122.59±2.23 and 133.71±3.55 respectively. Bowman’s membrane of cornea was measured 12.97±0.86, 17.22±0.55 and 18.71±0.68 in group I, II and III animals respectively. The mean thickness (µm) of corneal stroma in group I to III animals was 600.75±10.33, 672.22±10.46 and 690.00±5.32 respectively. This was mainly due to progressive increase in number of collagenous lamellae. The keratocytes became thin in old animals. Thickness of posterior band zone (PBZ) of Descemet’s membrane was increased with advancement of age. The mean thickness (µm) of Descemet’s membrane and endothelium together was in group I, II and III animals was 16.48±0.91, 41.29±2.25 and 54.82±1.44 respectively. The corneal endothelial cells were enlarged and increased in size in old buffaloes. The age related pigmentation was also noticed in epithelium and stroma of cornea in animals of group III. Density of sub basal nerve plexuses between the stroma and the corneal epithelium was not altered with advancement of age.


2016 ◽  
Vol 46 (8) ◽  
pp. 1466-1471 ◽  
Author(s):  
Flor Diana Yokoay Claros Chacaltana ◽  
João Antonio Tadeu Pigatto ◽  
Ione Terezinha Denardin

ABSTRACT: The aim of this research was to measure the intraocular pressure (IOP) of normal chinchilla eyes using the rebound tonometer. A further aim was to assess whether there were differences in the values of intraocular pressure in relation to animals age, gender and time of day. Thirty-six chinchillas were divided into three groups of 12 chinchillas each, by age: Group I (2-6-month-old), Group II (20 and 34 months) and Group III (37 and 135 months). Ophthalmic examination was performed previously by Schirmer tear test, slit lamp biomicroscopy, indirect ophthalmoscopy and fluorescein test in all chinchillas. Three measurements of intraocular pressure were assessed on the same day (7, 12 and 19h). Tonometry was performed on both eyes using the rebound tonometer after calibration in "p" mode. Statistical analysis was performed with SigmaPlot for Windows. The mean IOP for groups I, II and III were 2.47±0.581mmHg, 2.47±0.581mmHg and 2.51±0.531mmHg, respectively. No significant differences were reported between age and IOP and no significant differences were reported between the time of day and IOP. The IOP in chinchillas did not differ significantly between genders or ages of the animals, and did not change with time of day.


Author(s):  
Sergey K. Zyryanov ◽  
M.S. Chenkurov ◽  
Marina A. Ivzhits ◽  
Yu.A. Batechko ◽  
E.B. Ivanova ◽  
...  

Objective. To investigate the mortality rate, comorbidity prevalence, and etiology of community-acquired pneumonia (CAP) in elderly patient population. Materials and Methods. Hospitalized elderly patients with CAP were distributed into the following age groups: 65–74 years (group I), 75–84 years (group II) and 85–94 years (group III). The patients’ medical records were used for determining comorbidities and mortality rate. In order to determine etiology of CAP, sputum or BAL samples were collected. A total of 171 isolates were identified using MALDI-TOF MS. Results. The mortality rates were 27.1%, 31.5% and 45.7% in age groups I, II, III, respectively. The most common concomitant diseases in all age groups were arterial hypertension (47.4%, 54.6%, and 62.8% for groups I, II, and III, respectively), chronic heart failure (45.7%, 50.9%, and 60.0%, respectively), and coronary heart disease (15.2%, 25.9%, and 24.3%, respectively). The most frequently isolated bacteria by age group were the following: group I – non-fermenting Gram-negative bacteria (NFGNB) (7.4%), Enterobacterales (6.6%), S. aureus (6.6%); group II – Enterobacterales (13.9%), S. aureus (5.6%), Enterococcus spp. (5.6%), NFGNB (2.8%); group III – NFGNB (15.4%), S. aureus (7.7%), Enterococcus spp. (7.7%), Enerobacterales (7.7%). Conclusions. The mortality rates in elderly patients with CAP were high and varied from 27.1% in 65–74 years old patients to 45.7% in 85–94 years old patients. The most common comorbidities in all age groups were arterial hypertension (up to 62.8%), chronic heart failure (up to 60%), and coronary heart disease (up to 25.9%). The main pathogens causing CAP in elderly patient population were Enterobacterales and non-fermenting Gram-negative bacteria.


2020 ◽  
pp. 174462951990105 ◽  
Author(s):  
Heidi Elisabeth Nag ◽  
Terje Nærland

Smith–Magenis syndrome (SMS) is a genetic syndrome most often caused by a deletion on chromosome 17 or more rarely by a mutation in the retinoic acid-induced 1 gene. The aim of this study was to investigate the Developmental Behavior Checklist (DBC) profile of persons with SMS and the associations between behavioural and emotional problems, age, gender, adaptive behaviour and autism symptomatology. Twenty-eight persons with SMS were represented by their parents in this study. DBC Total scores are reduced with age, but they still show a mean that is clearly above the cut-off of 46. The differences between the age groups <9 years and 9–17 years ( p = 0.024) and between the age groups <9 years and >18 years ( p = 0.007) are significant. We found a significant decrease in behavioural and emotional problems with age in SMS. We did not find a relationship between adapted behaviour and communication and behavioural and emotional problems.


2020 ◽  
Vol 8 (10) ◽  
pp. 1581
Author(s):  
Minseok Kim ◽  
Tansol Park ◽  
Jung Im Yun ◽  
Hye Won Lim ◽  
Na Rae Han ◽  
...  

The microbiota of human skin is influenced by host and environmental factors. To determine if chronological age influences the composition of the skin microbiota on the forehead and hands, 73 Korean women were sorted into one of three age groups: (1) 10–29 years (n = 24), (2) 30–49 years (n = 21), and (3) 50–79 years (n = 28). From the 73 women, 146 skin samples (two skin sites per person) were collected. 16S rRNA gene amplicon sequencing was then conducted to analyze the skin microbiota. The overall microbial distribution varied on the forehead but was similar on the hands across the three age groups. In addition, the composition of the skin microbiota differed between the forehead and hands. Commensal microbiota, such as Streptococcus, Staphylococcus, Cutibacterium, and Corynebacterium, which contribute to maintaining skin health via dominant occupation, were affected by increasing age on forehead and hand skin. Alpha diversity indices increased significantly with age on forehead skin. This study indicates that older people may be more susceptible to pathogenic invasions due to an imbalanced skin microbiota resulting from age-related changes. The results of our study may help develop new strategies to rebalance skin microbiota shifted during aging.


2016 ◽  
Vol 31 (1) ◽  
pp. 12
Author(s):  
Marcela Lima Cardoso Selow ◽  
Flávia Lunelli ◽  
Iran Vieira ◽  
Mariana Doff Sotta ◽  
Wilson Denis Martins ◽  
...  

Objectives: Zinc plays an important role in the homeostasis of the human body. In the oral cavity, its absence causes hypogeusia. Zinc supplementation acts improving taste acuity and oral lesions healing. However, some aspects regarding to salivary zinc contents and syalometric variables, as well as, its variations among age-related groups, are lacking. The objective of this study was to measure the zinc concentration in the saliva in different age range.Methods: One hundred and twenty healthy individuals have donated saliva and they were divided in to four groups according to age: Group I = 18-29 years old; Group II = 30-39 years old; Group III: 40-49 years old and Group IV: 50-59 years old.Results: The research revealed that there are differences between salivary parameters, salivary flow rate, buffering capacity and pH, when they are correlated with the zinc present in saliva, but the salivary zinc concentration is not age dependent.Conclusion: pH and BA had no influence in the salivary zinc concentration, but the salivary flow can interfere in the zinc concentration.


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