HUBUNGAN ANTARA USIA, PARITAS, PEKERJAAN DAN INDEK MASSA TUBUH DENGAN KEJADIAN PROLAP ORGAN PANGGUL BERDASARKAN SKOR PELVIC ORGAN PROLAPSE QUANTIFICATION

2019 ◽  
Vol 2 (1) ◽  
pp. 39-44
Author(s):  
Ermawati Ermawati ◽  
Hafni Bachtiar

Prolap organ panggul merupakan kondisi yang mempengaruhi kualitas hidup wanita. Prolaps organ panggul ini dapat disebabkan oleh perlukaan sewaktu proses persalinan, proses penuaan, komposisi jaringan pada seorang wanita, batuk- batuk kronis, atau sering melakukan pekerjaan berat. Pengenalan dini prolaps terkait dengan prognosis pemulihan anatomik dan fungsional organ panggul. Hingga kini, penerapannya dalam dunia klinis belum banyak sehingga pelatihan dan pembelajaran lebih lanjut tentang pelvic organ prolapse quantification (POPQ) jelas diperlukan. Penelitian ini dilakukan dengan metode case control study di polikilinik Obgin RSUP. Dr. M. Djamil Padang mulai bulan September 2013 sampai jumlah sampel terpenuhi sebanyak 98 orang. Dengan 49 orang kelompok kontrol dan 49 orang kelompok kasus .Analisis dilakukan untuk menilai hubungan usia, paritas, pekerjaan dan indek massa tubuh dengan kejadian prolap organ panggul berdasarkan skor POPQ. Data disajikan dalam bentuk tabel. Data diuji dengan t test dan chi square test. Jika p<0,05 menunjukan hasil yang bermakna. Terdapat hubungan yang bermakna antara usia dengan kejadian prolap organ panggul dengan (p<0,05) dan OR 27,871.terdapat hubungan yang bermakna antara paritas dengan kejadian prolap organ panggul dengan (p<0,05) dan OR 52,970.Dari analisa statistik pekerjaan tidak bisa di uji secara statistik.indek massa tubuh tidak terdapat hubungan yang bermakna terhadap kejadian prolap organ panggul.(p>0,05)

Author(s):  
Prakruthi G. M. ◽  
Bharathi D. R. ◽  
Yogananda R.

Objective: Asthma is a chronic airway inflammatory disease in which many cells and cellular elements play a role often arising from allergies, subsequently cause shortness of breath, wheezing and coughing it affects children in different ways. To study the sociodemographic characteristics of asthmatic children and compare the predisposing factors of asthma in children.Methods: A Community based Case control study in selected schools in chitradurga for a period of 6 mo. A total of 90 children, among which 30 asthma children and 60 non asthma children were participated. Odds ratio will be calculated to know the strength of association. chi square test will be calculated to the significance.Results: A total of 90 children aged<14 y data. Female children are more exposed to asthma than male. In childhood asthma age group between 10-14years the age group of 10 y(26.7%) and 12 y (26.7%) were more exposed to the asthma.Conclusion: In Chitradurga city, the study area, is of no exception with regard to case control. From the total of 90 children selected for the study majority were found risk factors affected. It was due to their family history, exposure to pet animals, allergy, age group, BMI and sex.


Author(s):  
Nineetha Muraleedharan ◽  
M Saboora Beegum

Introduction: Preeclampsia is a cause of high morbidity and mortality in pregnant women. Serum albumin is found to be low in preeclampsia. Few recent studies have shown a state of hypothyroidism in preeclampsia. Aim: To find the association between the serum albumin and thyroid hormone levels in preeclampsia and seek to find if hypoalbuminemia increases the risk of hypothyroidism. Materials and Methods: A case-control study was done at Department of Biochemistry and the Department of Obstetrics and Gynaecology of Government Medical College, Thiruvananthapuram, Kerala, with 40 preeclampsia cases and 40 normal pregnant controls, in 30-38 week gestation. Serum albumin and thyroid profile-Total T3, Total T4, Thyroid Stimulating Hormone (TSH), freeT3 (fT3), freeT4 (fT4) were tested. Statistical analysis was done with Student’s t-test, Chi-square, Fischer’s t-test and Pearson’s correlation coefficients. Results: The mean serum albumin was significantly lesser in preeclampsia (3.11±0.39) than in controls (3.7±0.14 g/dL). Thyroid hormones were significantly decreased in preeclampsia. TSH was significantly raised (3.76±1.55 mIU/L) in preeclampsia compared to normal pregnant ladies (2.3±0.94 mIU/L). In cases with hypoalbuminemia, risk for hypothyroidism was 2.85 times compared to those with normal albumin but was not statistically significant. In severe preeclampsia, there was a two times increased risk. There was a negative correlation of TSH and positive correlation for fT4 with serum albumin. However, this was statistically not significant. Conclusion: Hypothyroidism in preeclampsia was not significantly correlated with hypoalbuminemia in this study. Thus hypoalbuminemia did not significantly increase the risk for hypothyroidism in our study. Further studies are needed to determine the risk factors affecting thyroid function in preeclampsia.


Author(s):  
Endalkachew H. Maru ◽  
Tigist W. Leulseged ◽  
Ishmael S. Hassen ◽  
Wuletaw C. Zewde ◽  
Nigat W. Chamesew ◽  
...  

ABSTRACTBackgroundAs the number of new cases and death due to COVID-19 is increasing, understanding the characteristics of severe COVID-19 patients and identifying characteristics that lead to death is a key to make an informed decision. In Ethiopia, as of September 27, 2020, a total of 72,700 cases and 1165 deaths were reported.ObjectiveThe study aimed to assess the determinants of death in Severe COVID-19 patients admitted to Millennium COVID-19 Care Center in Ethiopia.MethodsA case-control study of 147 Severe COVID-19 patients (49 deaths and 98 discharged alive cases) was conducted from August to September 2020. A comparison of underlying characteristics between cases (death) and controls (alive) was assessed using a chi-square test and an independent t-test with a p-value of <0.05 considered as having a statistically significant difference. Multivariable binary logistic regression was used to assess a statistically significant association between the predictor variables and outcome of Severe COVID-19 (Alive Vs Death) where Adjusted Odds ratio (AOR), 95% CIs for AOR, and P-values were used for testing significance and interpretation of results.ResultsHaving diabetes mellitus (AOR= 3.257, 95% CI= 1.348, 7.867, p-value=0.00), fever (AOR=0.328, 95% CI: 0.123, 0.878, p-value= 0.027) and Shortness of breath (AOR= 4.034, 95% CI= 1.481, 10.988, p-value=0.006) were found to be significant predictors of death in Severe COVID-19 patients.ConclusionsThe outcome of death in Severe COVID-19 patients is found to be associated with exposures to being diabetic and having SOB at admission. On the other hand, having a fever at admission was associated with a favorable outcome of being discharged alive.


2005 ◽  
Vol 192 (5) ◽  
pp. 1687-1691 ◽  
Author(s):  
Lily A. Arya ◽  
Joseph M. Novi ◽  
Alka Shaunik ◽  
Mark A. Morgan ◽  
Catherine S. Bradley

Author(s):  
M. Ahmad

<p class="abstract"><strong>Background:</strong> Cleft lip with or without an associated cleft palate (CLP) is one of the most common congenital birth defects. Both the frequency with which it occurs and the high psychosocial and financial costs associated with CLP contribute to a significant public health interest in the condition. The aim of the present study is to assess the nasal passage changes in repaired cleft lip and/or plate deformity with persons without any such deformity.</p><p><strong>Methods:</strong> It was a case-control study comprising of 2 groups. Carried out in 25 patients with 15 years and above admitted in plastic surgery or ENT Department of Gandhi Memorial and associated hospital or in patients in whom surgery has been performed earlier. After taking written informed consents from family members or legal guardians detailed history with presenting complaints was taken. Data entry and statistical analysis were performed using the Microsoft Excel and SPSS windows version 16.0 software. Tests of significance like Chi-square test are applied to find out the results.</p><p class="abstract"><strong>Results:</strong> Mean age of cases in 25.8 years and control 28.7. Deviation of nasal septum was present in 68% cases and 28% in control. Nasal obstruction left side in higher in cases than control. Deviation of nasal septum (L) was more common in cleft because most of the patient had cleft in left side. Caudal dislocation was also common in cleft. It was opposite to the side of cleft. It was common on right side because most of the patients have cleft on left side.</p><p><strong>Conclusions:</strong> Nasal airflow analysis would be particularly helpful in such investigations. The commonest presenting symptom is nasal obstruction. It is due to deviation of nasal septum.</p>


Author(s):  
Sergei Egorovich Khalchitsky ◽  
Marina Vanikovna Sogoyan ◽  
Alexei Nicolaevich Kozhevnikov ◽  
Sergei Valentinovich Vissarionov ◽  
Alexei Georgievich Baindurashvili

Introduction: Rheumatoid Arthritis (RA) is a chronic autoimmune disease with unknown pathogenesis. The disease is multifactorial, however, the exact causes of the occurrence, as well as the targets of the autoimmune process, are unknown. Genes candidate for a predisposition to RA are cytokine genes. Of the cytokines, IL-6 is considered a key mediator of systemic and localized inflammation in RA. Aim: The comparative analysis of the frequency distribution of alleles and genotypes IL-6 -174G/C polymorphism in patients with RA and in the control group to determine the genotype most characteristic of this disease. Materials and Methods: This case-control study was conducted in a group of 136 children with RA aged 14 to 18 years. In the control group, there were 143 practically healthy children of similar age without RA and orthopedic pathology. Both groups were tested for polymorphism IL-6 -174G/C using real-time Polymerase Chain Reaction (real-time PCR). The results were statistically processed using the Pearson's Chi-square test. Results: The distribution of -174G/C genotypes in the IL-6 gene is significantly different in patients with RA when compared with the control group. In patients with RA, heterozygous carriers of -174G/C (52.94%) prevail, while in the control group the most numerous group are homozygous carriers of -174G/G (40.56%). Conclusion: As a result of this study, it was possible to identify significant differences in the distribution of the genotypes -174 G/C polymorphism in the IL-6 gene between patients with RA and subjects of the control group. In relation to the European population of the Russian Federation, this polymorphism can serve as a diagnostic marker in the study of the pathogenesis of RA.


2018 ◽  
Vol 2 (2) ◽  
pp. 227-238
Author(s):  
Farissa Ulfa ◽  
Oktia Woro Kasmini Handayani

ABSTRAK Kasus demam tifoid di Kabupaten Tegal pada tahun 2016 yaitu sebanyak 11.387 kasus dan Puskesmas Pagiyanten merupakan puskesmas dengan jumlah kasus demam tifoid tertinggi yaitu sebanyak 377 kasus. Tujuan penelitian ini adalah untuk mengetahui faktor-faktor yang berhubungan dengan kejadian demam tifoid di Puskesmas Pagiyanten Kabupaten Tegal.  Jenis penelitian yang digunakan adalah studi case control dengan sampel sebesar 43 kasus dan 43 kontrol. Instrumen yang digunakan adalah lembar kuesioner. Analisis data dilakukan secara univariat dan bivariat dengan menggunakan uji chi-square. Hasil yang didapatkan faktor yang berhubungan dengan kejadian demam tifoid meliputi kebiasaan makan di luar rumah (p-value=0,001), kebiasaan mencuci tangan sebelum makan (p-value=0,02), kebiasaan mencuci tangan setelah BAB (p-value=0,04), kebiasaan mencuci bahan makanan mentah (p-value=0,007), dan jamban sehat (p-value=0,04). Simpulan penelitian ini adalah terdapat hubungan antara kebiasaan makan di luar rumah, kebiasaan mencuci tangan sebelum makan, kebiasaan mencuci tangan setelah BAB. kebiasaan mencuci bahan makanan mentah, dan jamban sehat dengan kejadian demam tifoid di Puskesmas Pagiyanten Kabupaten Tegal.   Kata Kunci: Faktor Risiko, Demam Tifoid   ABSTRACT Typhoid fever in Tegal regency in 2016 were 11,387 cases, and Puskesmas Pagiyanten with the highest number of cases of typhoid fever of 377 cases. The purpose of this study was to determine the factors associated with the incidence of typhoid fever in Puskesmas Pagiyanten Tegal regency. The research used case control study with 43 cases and 43 controls. The instrument used is a questionnaire. The data were analyzed by univariate and bivariate using chi-square test. The results of factors related to the occurrence of typhoid fever include eating habits outside the home (p-value=0.001), hand washing before eating habits (p-value=0.02), hand washing habit after defecate (p-value=0.04), the habit of washing raw food (p-value=0,007), and healthy latrines (p-value=0,04). The conclusion of this research is there is a relationship between eating habits outside the home, the habit of washing hands before eating, habit of washing hands after defecate, the habit of washing raw food, and healthy latrines with the incidence of typhoid fever in Puskesmas Pagiyanten Kabupaten Tegal. Keywords: Risk Factors, Typhoid Fever


Author(s):  
Cledinaldo Lira Junior ◽  
Diego Henrique Pires Gonçalves ◽  
Kamilly de Lourdes Ramalho Frazão ◽  
Sandra Aparecida Marinho ◽  
Sérgio Henrique Gonçalves De Carvalho ◽  
...  

Aims: To evaluate the mandibular bone cortical of patients with mucopolysaccharidosis on panoramic radiograph, through radiomorfometric indices. Study Design: Case-control study. Place and Duration of Study: Sample: Department of Diagnostic Imaging of the Universidade Estadual da Paraíba, Campus VIII, in the city of Araruna, PB, between January and December of 2015. Methodology: Panoramic radiographs of sixteen patients with mucopolysaccharidosis and 32 controls, organized by gender and age, composed the sample. The mandibular panoramic index, gonial index, antegonial index and mental index were evaluated. Pearson's Chi-square test, Fisher's exact test and Mann-Whitney test were used to statistical analysis with a level of significance of 5.0%. Results: Mucopolysaccharidosis patients were mostly female (62.5%), with a mean age of 12.31 + 7.16 years, MPS VI (50.0%) being the most prevalent. Patients with mucopolysaccharidosis had higher values in the gonial (1.86+0.48), the antegonical (4.36+1.24) and the mental (5.24+1.21). However, only the antegoniac index presented a significant difference (P=0.047). Conclusion: The antegoniac index was higher in patients with mucopolysaccharidosis and the other radiomorphometric measures were similar to those observed in the control group. Apparently, mucopolysaccharidosis is not related to decreased bone to mandibular quality.


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