scholarly journals Person of the Month: Karen Horney (1885-1952)

2017 ◽  
Vol 5 (1) ◽  
Author(s):  
Ankit Patel

Karen Horney (nee Danielson) was born near Hamburg, Germany on September 16, 1885. Her father was a religious, authoritarian ship’s captain, while her mother was a well-educated, more liberal intellectual who encouraged Danielson in her studies. Her father was a widower with four teenage children. Danielson was the second child from his new marriage, the first being a favoured older brother. Unflattering comments by her father relating to both her looks and her intelligence led Danielson to decide, at the age of nine, that if she couldn’t be pretty, then she would be smart. At age nine she also battled depression for the first time and would continue the battle throughout her life. At 13, Danielson decided she wanted to become a doctor – a lofty and perhaps not very realistic goal for a young woman in the late 19th century. Without her parents’ support, Danielson nonetheless entered medical school in 1906 as one of the first women to enter a German university. While there, she met economics major and aspiring law student, Oskar Horney, and the two married in 1909. It was not a particularly happy marriage although it did result in three daughters born between 1910 and 1916. Within the space of one year, Horney gave birth to her first daughter and lost both of her parents. She sought psychoanalysis to help her cope. Her analyst was Freud disciple Karl Abraham, who became her mentor at the Berlin Psychoanalytic Society where she became an analyst in private practice in addition to her hospital work. She helped design and eventually directed the Society’s training program, taught students, and conducted psychoanalytic research. Her roles as woman doctor, wife, and mother inspired her research on female sexual development, writing about the castration complex in women in 1924 and asserting – contrary to Freud – which the true source of penis envy was in the way female children were treated by their parents.

2020 ◽  
Vol 62 ◽  
pp. 32-38
Author(s):  
E. A. Dolmatov ◽  
R. B. Borzayev ◽  
A. N. Shaipov

The results of the study of the duration of the juvenile period of indigenous Chechen willow leaf pear genotypes (Pyrus salicifolia Pall.) are given in connection with the acceleration of the breeding process and the use of selected forms in pear breeding for high precocity. The studies were carried out in 2016-2019 at OOO “Orchards of Chechnya” in accordance with the Agreement on creative cooperation with the Russian Research Institute of Fruit Crop Breeding. The work was carried out in accordance with generally accepted programs and methods. The objects of the study were one-year and two-year-old pear seedlings obtained from sowing seeds of selected dwarf and low-growing local Chechen forms of willow pear (P. salicifolia Pall.), laying fruit buds on annual growths and seedlings of Caucasian pear (P. caucasica Fed.), 20 500 pcs. of each specie. The aim of the research was to study the potential of precocity of willow pear seedlings and to reveal of selected forms with the greatest degree of this trait. Stratified seeds were sown in the sowing department of the OOO “Orchards of Chechnya” production nursery in April, 2017. The seedlings were grown according to the common technology in dryland conditions on the plot with chestnut soil. The first fl owering of plants was noted in the spring, 2019. As a result of the research, for the first time on a large number of the experimental material it was found that in the off spring of the indigenous Chechen willow leaf pear genotypes, the selection of a little more than 2% of seedlings with a very short juvenile period (2 years) was possible. They are of great interest in accelerating the breeding process and in the selection of new pear varieties with high precocity. 20 willow leaf pear genotypes were selected for the further use in breeding for high precocity and as sources of the trait of short juvenile period.


2021 ◽  
Vol 12 (1) ◽  
pp. 17-26
Author(s):  
Genevieve C. Tuite ◽  
James A. Quintessenza ◽  
Alfred Asante-Korang ◽  
Sharon R. Ghazarian ◽  
Bethany L. Wisotzkey ◽  
...  

Background: To assess changes in patterns of practice and outcomes over time, we reviewed all patients who underwent heart transplantation (HTx) at our institution and compared two consecutive eras with significantly different immunosuppressive protocols (cohort 1 [80 HTx, June 1995-June 2006]; cohort 2 [108 HTx, July 2006-September 2018]). Methods: Retrospective study of 180 patients undergoing 188 HTx (June 1995-September 2018; 176 first time HTx, 10 second HTx, and 2 third HTx). In 2006, we commenced pre-HTx desensitization for highly sensitized patients and started using tacrolimus as our primary postoperative immunosuppressive agent. The primary outcome was mortality. Survival was modeled by the Kaplan-Meier method. Univariable and multivariable Cox proportional hazard models were created to identify prognostic factors for survival. Results: Our 188 HTx included 18 neonates, 85 infants, 83 children, and 2 adults (>18 years). Median age was 260.0 days (range: 5 days-23.8 years). Median weight was 7.5 kg (range: 2.2-113 kg). Patients in cohort 1 were less likely to have been immunosensitized preoperatively (12.5% vs 28.7%, P = .017). Nevertheless, Kaplan-Meier analysis suggested superior survival in cohort 2 ( P = .0045). Patients in cohort 2 were more likely to be alive one year, five years, and ten years after HTx. Multivariable analysis identified the earlier era (hazard ratio [HR] [95% confidence interval] for recent era = 0.32 [0.14-0.73]), transplantation after prior Norwood operation (HR = 4.44 [1.46-13.46]), and number of prior cardiac operations (HR = 1.33 [1.03-1.71]) as risk factors for mortality. Conclusions: Our analysis of 23 years of pediatric and congenital HTx reveals superior survival in the most recent 12-year era, despite the higher proportion of patients with elevated panel reactive antibody in the most recent era. This improvement was temporally associated with changes in our immunosuppressive strategy.


Author(s):  
László Holló

"In less than one year, the Catholic Church, just like the other denominations, lost its school network built along the centuries. This was the moment when the bishop wrote: “No one can resent if we shed tears over the loss of our schools and educational institutions”. Moreover, he stated that he would do everything to re-store the injustice since they could not resent if we used all the legal possibilities and instruments to retrieve our schools that we were illegally dispossessed of. Furthermore, he evaluated the situation realistically and warned the families to be more responsible. He emphasized the parents’ responsibility. First and foremost, the mother was the child’s first teacher of religion. She taught him the first prayers; he heard about God, Jesus, the Virgin Mary, and the angels from his mother for the first time. He asked for the mothers’ and the parents’ support also in mastering the teachings of the faith. Earlier, he already instructed the priests to organize extramu-ral biblical classes for the children and youth. At this point, he asked the families to cooperate effectively, especially to lead an ardent, exemplary religious life, so that the children would grow up in a religious and moral life according to God’s will, learn-ing from the parents’ examples. And just as on many other occasions throughout history, the Catholic Church started building again. It did not build spectacular-looking churches and schools but rather modest catechism halls to bring communities together. These were the places where the priests of the dioceses led by the bishop’s example and assuming all the persecutions, incessantly educated the school children to the love of God and of their brethren, and the children even more zealously attended the catechism classes, ignoring their teachers’ prohibitions. Keywords: Márton Áron, Diocese of Transylvania, confessional religious education, communism, nationalization of catholic schools, Catholic Church in Romania in 1948."


Stroke ◽  
2021 ◽  
Vol 52 (Suppl_1) ◽  
Author(s):  
Durgesh Chaudhary ◽  
Ayesha Khan ◽  
Mudit Gupta ◽  
Yirui Hu ◽  
Jiang Li ◽  
...  

Introduction: Obesity is an established risk factor for ischemic stroke but the association of increased body mass index (BMI) with survival after ischemic stroke remains controversial. Many studies have shown that increased BMI has a “protective” effect on survival after stroke while other studies have debunked the obesity paradox. This study aimed at examining the relationship between BMI and all-cause mortality at one year in first-time ischemic stroke patients using data extracted from different resources including electronic health records. Methods: We analyzed consecutive ischemic stroke patients captured in the Geisinger NeuroScience Ischemic Stroke (GNSIS) database. Survival in first-time ischemic stroke patients was analyzed using Kaplan-Meier estimator, stratified by different BMI categories. The predictors of mortality at one-year were assessed using a multivariate Cox proportional hazards model. Results: Among 6,703 first-time adult ischemic stroke patients, mean age was 70.2 ±13.5 years and 52% were men. Of these patients, 24% patients were non-overweight (BMI < 25), 34% were overweight (BMI 25-29.9) and 41% were obese (BMI ≥ 30). One-year survival probability was significantly higher in overweight patients (87%, 95% CI: [85.6 - 88.4], p<0.001) and obese patients (89.5%, 95% CI: [88.4 - 90.7], p<0.001) compared to non-overweight patients (78.1%, 95% CI: [76.0 - 80.1]). In multivariate analysis, one-year mortality was significantly lower in overweight and obese patients (overweight patients- HR = 0.61 [95% CI, 0.52 - 0.72]; obese patients- HR = 0.56 [95% CI, 0.48 - 0.67]). Other significant predictors of one-year mortality were age at the ischemic stroke event (HR = 1.04 [95% CI, 1.03 - 1.04]), history of neoplasm (HR = 1.59 [95% CI, 1.38 - 1.85]), atrial fibrillation or flutter (HR = 1.26 [95% CI, 1.09 - 1.46]), heart failure (HR = 1.68 [95% CI, 1.42 - 1.98]), diabetes mellitus (HR = 1.27 [95% CI, 1.1 - 1.47]), rheumatic disease (HR = 1.37 [95% CI, 1.05 - 1.78]) and myocardial infarction ((HR = 1.23 [95% CI, 1.02 - 1.48]). Conclusion: Our results support the obesity paradox in ischemic stroke patients as shown by a significantly decreased hazard ratio for one-year mortality among overweight and obese patients in comparison to non-overweight patients.


2019 ◽  
Vol 8 ◽  
pp. e1148
Author(s):  
Elnaz Razavian ◽  
Setareh Tehrani

Background: The 33-mg/mL hyaluronic acid (HA) formulation is a highly concentrated, cross-linked, cohesive, smooth, and completely reversible volumizing filler approved by Conformité Européene. For the first time, we aimed to evaluate the long-term efficacy and safety of the 33-mg/mL HA filler for soft tissue augmentation in the treatment of facial wrinkles. Materials and Methods: After optimal wrinkle correction was achieved in the patients undergoing treatment by injecting the 33-mg/mL HA filler at the injection site plus one touch-up at a 2-week interval, the safety and efficacy of the filler were assessed on the 5-point Facial Volume Loss Scale through the 1-year study period. Patients were evaluated daily for 14 days and after 6 and 12 months post-treatment. Results: A total of 86 subjects were treated. The mean wrinkle scores of the patients were 3.95+0.79 (range of 3-5) before treatment, 2.3+0.94 (range 1-5) six months after treatment, and 2.93+1.29 (range of 1-5) one year after treatment. Clinically significant mean wrinkle correction (P=0.001) was still evident at>12 months of treatment through 33-mg/mL HA formulation. A clinically significant correction at>12 months after treatment was maintained by 79% of patients. Nodule formation and swelling were more frequent when the 33-mg/mL HA filler was used compared with the use of less concentrated HA fillers. One patient developed angioedema-like swelling and induration last few months. Conclusion: The 33-mg/mL HA filler can provide long-term correction lasting for one year or more. Adverse effects, especially swelling and nodule formation were more common in this filler compared with less concentrated HA fillers. The side effects were correlated with the volume of the injected filler. We recommend using this concentration with low volume or combining high volume with lower concentration. [GMJ.2019;8:e1148]


Author(s):  
Papia Khatun ◽  
Ziaul Haque ◽  
Shonkor Kumar Das

The microscopic features of the testis were studied in gonadally inactive Khaki Campbell duck (Anas platyrhynchos domesticus) in Bangladesh. The study was conducted in the Department of Anatomy & Histology, Bangladesh Agricultural University, Mymensingh. Five adult healthy birds of one-year-old were used for this study. The testes were collected immediately after ethical killing of the birds for histological observations. The collected tissue samples were then processed and stained with Hematoxylene & Eosin (H & E) stain for histological observations. The seminiferous tubules showed considerable involution with cessation of spermatogenesis. The basal lamina of the seminiferous tubules was irregular in outline and was invaginated into the germinal epithelium in the form of finger-like plicae or folds. Most of the lumen of the seminiferous tubules was empty and all generation of germ cells were not present in most of the seminifeous tubules. The interstitium showed a relative increase in volume and interstitial tissue consisted of loose connective tissue, interstitial cells (Leydig cells), few connective cells and blood vessels. This study first time described the microscopic features of testis of Khaki Campbell ducks in Bangladesh during inactive phases of the reproductive cycle.


2011 ◽  
Vol 63 (3) ◽  
pp. 785-798 ◽  
Author(s):  
Naser Jafari ◽  
Mohamad Nabavi ◽  
Moslem Akhavan

The influence of physicochemical properties of Haraz river on its zooplankton composition and abundance were investigated at three sites for one year between August 2009 and July 2010. The present study records for the first time the aspects of zooplankton diversity and composition in relation to the physicochemical environment of the Haraz river. Only three groups of zooplankton were found: Rotifera with eighteen genera; Cladocera with nine and Copepoda with six genera. Rotifera was the predominant group (64.89%), followed by Cladocera (19.62%) and Copepoda (15.32%). Upstream, the abundance was 805 individuals/m3, while it varied from 922 to 1126 ind/m3 downstream. Alkaline pH and nutrients were the main environmental factors which affected zooplankton abundance in the river. Site variation in dominance, diversity, evenness and richness were calculated. The study revealed that the presence of certain species, such as Lepadella sp., Mesocyclops sp., Polyarthra sp. and Brachionus sp. is considered to be a biological indicator for eutrophication. The calculated Jack1 values of sites 1 to 3 were 7.624, 16.426 and 19.221, respectively. The Shannon-Wiever species diversity index (H?) values were also different for all the three sites viz., site 1 (1.992), site 2 (1.21) and site 3 (2.48). Simpson?s dominance index (H) value was highest at site 1 (0.692), indicating maximum dominance, whereas at site 3 dominance was the lowest (0.227) and diversity was the highest. Overall, our results showed that changes in the water quality of the river Haraz have considerable effects on the composition of zooplankton assemblages that can potentially affect the functioning of these ecosystems.


2014 ◽  
Vol 112 (07) ◽  
pp. 73-78 ◽  
Author(s):  
Thomas Bergholt ◽  
Anne Nielsen ◽  
Michael J. Paidas ◽  
Ellen Christine L. Løkkegaard ◽  
Jesper Petersen

SummaryEstimating the risk of venous thromboembolism (VTE) associated with combined hormonal contraceptives following early terminated pregnancies or birth, a Danish nationwide retrospective cohort observing a one-year follow-up was defined using three unique registries. All Danish women with confirmed pregnancies aged 15–49 during the period of 1995–2009 were included. The main outcomes were relative and absolute risks of first time venous thromboembolism in users as well as non-users of combined hormonal contraceptives. In 985,569 person-years, 598 venous thromboembolisms were recorded. After early terminated pregnancies and births, respectively, 113 and 485 events occurred in 212,552 and 773,017 person-years. After early terminated pregnancies, the crude VTE incidence ratios were similar, and the numbers needed to harm were equal between groups that did or did not use combined hormonal contraceptives throughout the follow-up year. After childbirth, individuals that used combined hormonal contraceptives were more likely than non-users to experience VTE depicted by crude incidence ratios; however, the difference was only significant after 14 weeks. This implied that the numbers needed to harm were lower for those that used compared to those that did not use combined oral contraceptives in the initial 14 weeks postpartum. In conclusion, the use of combined hormonal contraceptives after early terminated pregnancies was not detrimental, but during the puerperal period, they should be used with caution.


The Lancet ◽  
2016 ◽  
Vol 388 ◽  
pp. S96 ◽  
Author(s):  
Xianglong Xu ◽  
Hanxiao Zuo ◽  
Yunshuang Rao ◽  
Lei Zhang ◽  
Lian Lian Wang ◽  
...  

Thorax ◽  
2019 ◽  
Vol 75 (2) ◽  
pp. 172-175 ◽  
Author(s):  
Steve Cunningham ◽  
Catriona Graham ◽  
Morag MacLean ◽  
Paul Aurora ◽  
Michael Ashworth ◽  
...  

We performed a prospective, observational, cohort study of children newly diagnosed with children’s interstitial lung disease (ChILD), with structured follow-up at 4, 8, 12 weeks and 6 and 12 months. 127 children, median age 0.9 (IQR 0.3–7.9) years had dyspnoea (68%, 69/102), tachypnoea (75%, 77/103) and low oxygen saturation (SpO2) median 92% (IQR 88–96). Death (n=20, 16%) was the most common in those <6 months of age with SpO2<94% and developmental/surfactant disorders. We report for the first time that ChILD survivors improved multiple clinical parameters within 8–12 weeks of diagnosis. These data can inform family discussions and support clinical trial measurements.


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