scholarly journals Synsepalum Dulcificum: A Review

2020 ◽  
Vol 11 (3) ◽  
pp. 4208-4213
Author(s):  
Sadhana H M ◽  
Suresh Joghee ◽  
Hamsalakshmi
Keyword(s):  
Chemical Constituents ◽  
Sweet Taste ◽  
Literature Survey ◽  
The Internet ◽  
Research Papers ◽  
Pharmacological Activities ◽  
Current Review ◽  
Anti Cancer ◽  
Reported Health ◽  
Transgenic Tomatoes

Synsepalum dulcificum also regarded as a miracle berry, belonging to the Sapotaceae family. It is cultivated for its mild fruits, which makes sour foods to give a sweet taste, the effect lasts for about 30 minutes. The plant is a shrub, containing red coloured fruits and localised to West Africa. They used this plant as their palm wine and also used this for certain other beverages to make it sweetened regionally. Because of its remarkable sweet potential used to make the sour foods taste sweet. Miraculin is the glycoprotein present in the plant responsible for the sweet taste. Some of the reported health benefits are anti-diabetic, effective food enhancer, taste disorder in cancer, alter the taste. The plant is known for its production of transgenic tomatoes. Ethnobotany uses of the plants includes in the treatment of male infertility, Asthma, Haemorrhoids, Anti-cancer etc. The aim of the present review was to brief the literature survey of the plant through the internet like PubMed and Google scholar for forming the platform to illustrate the ethnopharmacology of the plant, information about the traditional usage, important chemical constituents and selected pharmacological activities of the plant were gathered from available research papers to frame the review. The current review also highlights the phytochemical and pharmacological aspects of Synsepalum dulcificum which will have been helped in the researchers for the further qualitative research.

Ethnomedicinal uses, Phytochemistry and Pharmacological Aspects of the Genus Berberis Linn: A Comprehensive Review

2020 ◽  
Vol 23 ◽  
Author(s):  
Roohi Mohi-ud-din ◽  
Reyaz Hassan Mir ◽  
Prince Ahad Mir ◽  
Saeema Farooq ◽  
Syed Naiem Raza ◽  
...  
Keyword(s):  
Chemical Constituents ◽  
Pharmacological Activities ◽  
Traditional Use ◽  
Comprehensive Review ◽  
Wide Range ◽  
Anti Cancer ◽  
Comprehensive Survey ◽  
Ethnomedicinal Uses

Background: Genus Berberis (family Berberidaceae), which contains about 650 species and 17 genera worldwide, has been used in folklore and various traditional medicine systems. Berberis Linn. is the most established group among genera with around 450-500 species across the world. This comprehensive review will not only help researchers for further evaluation but also provide substantial information for future exploitation of species to develop novel herbal formulations. Objective: The present review is focussed to summarize and collect the updated review of information of Genus Berberis species reported to date regarding their ethnomedicinal information, chemical constituents, traditional/folklore use, and reported pharmacological activities on more than 40 species of Berberis. Conclusion: A comprehensive survey of the literature reveals that various species of the genus possess various phytoconstituents mainly alkaloids, flavonoid based compounds isolated from different parts of a plant with a wide range of pharmacological activities. So far, many pharmacological activities like anti-cancer, anti-hyperlipidemic, hepatoprotective, immunomodulatory, anti-inflammatory both in vitro & in vivo and clinical study of different extracts/isolated compounds of different species of Berberis have been reported, proving their importance as a medicinal plant and claiming their traditional use.

Phytochemical, Pharmacological Activities and Ayurvedic Significances of Magical Plant Mimosa pudica Linn

2020 ◽  
Vol 17 ◽  
Author(s):  
Vijay Kumar
Keyword(s):  
Therapeutic Potential ◽  
Wide Spectrum ◽  
Chemical Constituents ◽  
Future Research ◽  
Mimosa Pudica ◽  
Pharmacological Activities ◽  
Medicinal Uses ◽  
Traditional Medicines ◽  
Crude Extracts ◽  
Anti Cancer

: Mimosa pudica Linn is an integrated part of Traditional Medicines Systems of India, China, Africa, Korea and America. It has been used from centuries in traditional medicines to cure different diseases like fever, diabetes, constipation, jaundice, ulcers, biliousness, and dyspepsia. It is an important ingredient of wide class of herbal formulations. To assess the scientific evidence for therapeutic potential of Mimosa pudica Linn and to identify the gaps for future research. The available information on the ethno-medicinal uses, phytochemistry, pharmacology and toxicology of Mimosa pudica Linn was collected via a library and electronic searches in Sci-Finder, Pub-Med, Science Direct, Google Scholar for the period, 1990 to 2020. In traditional medicinal systems, variety of ethno-medicinal applications of Mimosa pudica Linn has been noticed. Phytochemical investigation has resulted in identification of 40 well known chemical constituents, among which alkaloids, phenols and flavionoids are the predominant groups. The crude extracts and isolates have exhibited a wide spectrum of in vitro and in vivo pharmacological activities including anti-cancer, anti-inflammation, osteoporosis, neurological disorders, hypertension etc.. To quantify the Mimosa pudica Linn and its formulations, analytical techniques like HPLC and HPTLC has shown dominancy with good range of recovery and detection limit. Mimosa pudica Linn is the well-known herb since an ancient time. The pharmacological results supported some of the applications of Mimosa pudica Linn in traditional medicine systems. Perhaps, the predominance of alkaloids, phenols and flavionoids are responsible for the pharmacological activities the crude extracts and isolates of Mimosa pudica Linn. Further, there is need to isolate and evaluate the active chemical constituents of Mimosa pudica Linn having significant medicinal values. In future, it is important to study the exact mechanism associated with the phytochemicals of Mimosa pudica Linn especially on anti-cancer activities. Notably, toxicity studies on Mimosa pudica Linn are limited which are to be explored in future for the safe application of Mimosa pudica Linn and its formulations.

Phytochemical and Pharmacological Review on Two Herbs of Baijiangcao: Patrinia scabiosaefolia Fisch. ex Trev. and Patrinia villosa (Thunb.) Juss

2020 ◽  
Vol 17 (5) ◽  
pp. 496-517
Author(s):  
Yangcheng Liu ◽  
Wei Liu ◽  
Jiaqi Wang ◽  
Yang Liu ◽  
Changlan Chen ◽  
...  
Keyword(s):  
Chemical Constituents ◽  
Volatile Components ◽  
Research Papers ◽  
Pharmacological Activities ◽  
Comprehensive Review ◽  
Scientific Databases ◽  
The Past ◽  
Current State ◽  
Patrinia Scabiosaefolia ◽  
Antiviral Activities

Patrinia scabiosaefolia Fisch. Trev. and Patrinia villosa (Thunb.) Juss, are two species of Patrinia recorded in the Chinese Pharmacopoeia with the same Chinese name “Baijiangcao” and similar therapeutic effect in traditional Chinese medicine. The present article is the first comprehensive review on the chemical composition and pharmacological activities of these herbs. In this review, data on chemical constituents and pharmacological profile of the two herbs are provided. This review discusses all the classes of the 223 compounds (phenylpropanoids, flavonoids, terpenes, saponins and volatile components, etc.) detected in the two herbs providing information on the current state of knowledge of the phytochemicals present in them. In the past three years, our research group has isolated and identified about more than 100 ingredients from the two herbs. Therefore, we published a systematic review of our research papers and studies on the two herbs were carried out using resources such as classic books about Chinese herbal medicine and scientific databases including Pubmed, Web of Science, SciFinder, CNKI. etc. The present review discusses the most thoroughly studied pharmacological activities (antioxidant, anti-inflammatory, immunomodulatory, antimicrobial, antitumor and antiviral activities) of the two herbs. This comprehensive review will be informative for scientists searching for new properties of these herbs and will be important and significant for the discovery of bioactive compounds from the two herbs and in complete utilization of Patrinia scabiosaefolia Fisch. ex Trev. and Patrinia villosa (Thunb.) Juss.

scholarly journals Emerging cellular and molecular mechanisms underlying anticancer indications of chrysin

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Marjan Talebi ◽  
Mohsen Talebi ◽  
Tahereh Farkhondeh ◽  
Jesus Simal-Gandara ◽  
Dalia M. Kopustinskiene ◽  
...  
Keyword(s):  
Blood Cells ◽  
Molecular Mechanisms ◽  
Web Of Science ◽  
Experimental Studies ◽  
Protective Effects ◽  
Pharmacological Activities ◽  
Current Review ◽  
Mesh Terms ◽  
Online Databases ◽  
Anti Cancer

AbstractChrysin has been shown to exert several beneficial pharmacological activities. Chrysin has anti-cancer, anti-viral, anti-diabetic, neuroprotective, cardioprotective, hepatoprotective, and renoprotective as well as gastrointestinal, respiratory, reproductive, ocular, and skin protective effects through modulating signaling pathway involved in apoptosis, oxidative stress, and inflammation. In the current review, we discussed the emerging cellular and molecular mechanisms underlying therapeutic indications of chrysin in various cancers. Online databases comprising Scopus, PubMed, Embase, ProQuest, Science Direct, Web of Science, and the search engine Google Scholar were searched for available and eligible research articles. The search was conducted by using MeSH terms and keywords in title, abstract, and keywords. In conclusion, experimental studies indicated that chrysin could ameliorate cancers of the breast, gastrointestinal tract, liver and hepatocytes, bladder, male and female reproductive systems, choroid, respiratory tract, thyroid, skin, eye, brain, blood cells, leukemia, osteoblast, and lymph. However, more studies are needed to enhance the bioavailability of chrysin and evaluate this agent in clinical trial studies. Graphic abstract

scholarly journals TERMINALIA CHEBULA: SUCCESS FROM BOTANY TO ALLOPATHIC AND AYURVEDIC PHARMACY

2016 ◽  
Vol 9 (5) ◽  
pp. 21
Author(s):  
Varun Garg ◽  
Barinder Kaur ◽  
Sachin Kumar Singh ◽  
Bimlesh Kumar
Keyword(s):  
Chemical Constituents ◽  
Present Review ◽  
Terminalia Chebula ◽  
Pharmacological Activities ◽  
Therapeutic Uses ◽  
Anti Cancer ◽  
Anti Oxidant ◽  
Anti Inflammatory

ABSTRACTTerminalia chebula (TC) is a unique herb having various therapeutic potentials as anti-inflammatory, antioxidant, anticancer, and digestant. It belongsto family Combretaceae. In the present review, an attempt has been made to decipher classification, chemical constituents, therapeutic uses, andpatents that have been reported for TC. Various pharmacological activities of TC that make it as potential medicine and its Ayurvedic formulationsare highlighted.Keywords: Terminalia chebula, Anti-oxidant, Anti-cancer, Ayurvedic formulations, Anti-oxidant.

scholarly journals Andrographis Paniculata – A Review

2020 ◽  
Vol 11 (4) ◽  
pp. 5395-5400
Author(s):  
Sadhana H M ◽  
Suresh Joghee ◽  
Hamsalakshmi
Keyword(s):  
Chemical Constituents ◽  
Andrographis Paniculata ◽  
Major Constituent ◽  
Traditional System ◽  
Regular Treatment ◽  
Whole Plant ◽  
Anti Cancer ◽  
The Family ◽  
Reported Health ◽  
Essential Chemical

Andrographis paniculata (AP) is commonly known as creat or green chiretta belongs to the family Acanthaceae. It is also known as Kalmegh and popularly called as King of bitters. It was widely used in the traditional system of medicines such as Siddha system, Ayurvedic system and Chinese medicine for the regular treatment of a common cold. Some of the reported health benefits are Antidiabetic, Antipyretic, Hepatoprotective, Antioxidant, Antimalarial, Anti-cancer, Antityphoid, Anti-diarrhoea, antioedema, etc. Whole plant possesses medicinal property and leaves are explicitly used for therapeutic care. The plant contains four major diterpenoids such as andrographolide, neoandrographolide,14-deoxyandrographolide, 14-deoxy-11,12-didehydroandrographolide and also includes other phytoconstituents such as flavonoidssesquiterpene lactones, etc. Andrographolide is found as major constituent in the leaves and reported for a wide variety of pharmacological activities. The purpose of this review is to brief the plant's literature survey via internet sources such as google scholar and PubMed providing a medium to explain the plant's ethnobotany information on conventional usage, essential chemical constituents and selected plant pharmacology activities are obtained from existing research articles to frame the review. The present analysis also illustrates the pharmacological and phytochemical characteristics of Andrographis paniculata from which researchers may get benefited for further qualitative research.

scholarly journals ANTI-CANCER ACTIVITY OF CUMINUM CYMINUM: A REVIEW.

2018 ◽  
Vol 6 (04) ◽  
Author(s):  
NIKHIL ARUN CHAUDHARI ◽  
NINAD SATHE
Keyword(s):  
Biologically Active ◽  
Research Papers ◽  
Cuminum Cyminum ◽  
Current Review ◽  
Therapeutic Value ◽  
Wide Range ◽  
Anti Cancer ◽  
Phytochemical Constituents ◽  
Herbal Plant ◽  
Cancer Activity

Jeeraka, commonly known as cumin (Cuminum cyminum Linn.) (Family: Umbelliferae), is a popular herbal plant in traditional ayurvedic medicine, which has since long used as antioxidant, gastric stimulant, anti-flatulence, anti-diarrheal, sprue, anthelmintic, galactagogue, diuretic, astringent, carminative. This plant is pharmacologically and clinically evaluated for various activities like antioxidant, aphrodisiac, antimicrobial, hepato-protective, and anti-inflammatory. It is promulgated to possess a wide range of many phytochemical constituents. The current review is presented to give a comprehensive account of all anti-cancer activities of cumin. It will be helpful to create interest towards cumin and may be useful in developing new and economical anti-cancer formulations with more therapeutic value. The part used of the selected plant is seed. As per retrospective review cumin seed, its essential oil, ethanoic extract and 1­(2­Ethyl, 6­Heptyl) Phenol (EHP), a biologically active compound formerly extracted by benzene are found having anti-cancer activity against 13 different cell lines of various origins and 6 animal models. Also, it can be used as chemopreventive ingredient in the herbal anti-cancer formulation. Total 8 research articles, peer viewed research papers, abstracts and classical texts were reviewed.

scholarly journals CHEMICAL CONSTITUENTS AND PHARMACOLOGICAL ACTIVITIES OF LANTANA CAMARA – A REVIEW

2019 ◽  
pp. 10-20
Author(s):  
ALI ESMAIL AL-SNAFI
Keyword(s):  
Chemical Constituents ◽  
Lantana Camara ◽  
Pharmacological Effects ◽  
Pharmacological Activities ◽  
Thrombin Inhibition ◽  
Current Review ◽  
Anthraquinone Glycosides ◽  
Wide Range ◽  
Web Science ◽  
Pharmacological Studies

Objective: The review was designed to investigate the traditional uses, chemical constituents and pharmacological effects of Lantana camara. Methods: In the current review, databases including Web Science, Pub Med, Scopus and Science Direct, were searched to investigate the chemical constituents and pharmacological effects of Lantana camara. Results: The plant contained alkaloids, glycosides, steroids, saponins, flavanoids, coumarins, tannins, carbohydrates, hydroxy anthraquinones, anthraquinone glycosides, proteins, phytosteroids, fixed oils, fats, and triterpinoids. Previous pharmacological studies revealed that Lantana camara possessed antimicrobial, antiparasitic, anxiolytic, gastrointestinal, hypoglycemic, cardiovascular, antioxidant, anticancer, antiinflammatory, analgesic, wound healing, antiurolithiatic, hepatoprotective, reproductive, anti–hemorrhoidal, thrombin inhibition and many other effects. Conclusion: Lantana camara represents a promising medicinal plant with a wide range of pharmacological activities that could be utilized in several medical applications because of its effectiveness and safety.

A Review of Various Pharmacological Effects of Quercetin with its Barriers and Approaches for Solubility and Permeability Enhancement

2021 ◽  
Vol 11 ◽  
Author(s):  
Rakesh Mishra ◽  
Shweta Kulkarni
Keyword(s):  
Solid Dispersions ◽  
Aqueous Solubility ◽  
Pharmacological Effects ◽  
Pharmacological Activities ◽  
Human Diet ◽  
Permeability Enhancement ◽  
Current Review ◽  
Anti Cancer ◽  
Anti Oxidant ◽  
Novel Approaches

Background: Quercetin, one of the most beneficial flavonoids, has been included in the human diet due to its therapeutic effect on health. Recently, Quercetin is gaining scientific attraction for its multifarious activities, including anti-oxidant, anti-inflammatory, antiviral, anti-diabetic, anti-cancer, anti-arthritic, as well as function to ease some cardiovascular diseases. However, these applications of quercetin in the pharmaceutical field are limited due to its poor aqueous solubility and poor permeability. Objective: The present review summarizes various pharmacological activities of quercetin, analyses the barriers like solubility and permeability, which restrict the therapeutic efficiency of quercetin, and also discusses novel approaches to enhance aqueous solubility and permeability of quercetin for its effective clinical use. Methods: The current review information sources were peer-reviewed relevant scientific articles of recognized journals from scientific engines and databases (Scopus, Web of Science, PubMed, Science Direct, Google Scholar) using different key words related to quercetin pharmacological effects, mechanism, solubility, permeability, absorption barriers, and formulation approaches. Results: Various novel approaches, including solid dispersions, inclusion complex, pro-drugs, nanoemulsion, micelles, liposomes, SNEEDS, and microspheres, have been developed to overcome the solubility and permeability barriers for efficient quercetin delivery. Conclusion: This review revealed that the multifaceted pharmacological activities of quercetin for management of various disease are enormously dependent on the development of novel and safe drug delivery systems of quercetin.

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