2019 Novel Coronavirus: A mysterious threat from Wuhan, China–A current review

2020 ◽  
Vol 11 (SPL1) ◽  
pp. 7-15 ◽  
Author(s):  
Ramalingam Kothai ◽  
Balasubramanian Arul
Keyword(s):  
Risk Groups ◽  
Diagnostic Methods ◽  
World Health ◽  
The Public ◽  
Current Review ◽  
The Common ◽  
Novel Coronavirus ◽  
Health Organization ◽  
A Current ◽  
Indian Scenario

Coronaviruses (CoV) are a huge family of viruses and they cause various diseases from the common cold to very serious illnesses. They also just like the Middle East Respiratory Syndrome (MERS-CoV) and Severe Acute Respiratory Syndrome (SARS-CoV). But novel coronavirus (nCoV) is a different strain and newly discovered in humans. Several known coronaviruses circulate in animals not yet infected by humans. It is also a zoonotic virus, which means that they are spread between animals and then to humans. Comprehensive studies showed that SARS-CoV was transmitted to humans by civet cats and MERS-CoV by dromedary camels. Respiratory symptoms, fever, cough, shortness of breath and difficulty in breathing are common signs of infection. It was started from Huanan wholesale seafood market with the admission of 2-3 patients and now crossed 37251 cases with 812 deaths as on 9th February. In some of the days, the number of new admissions was more than 3000 cases continuously. This review summarises the types, morphology, origin, transmission, symptoms, diagnostic methods, Chinese, global and Indian scenario of this novel deadly virus. The world health organization advises for the public about the avoiding of the spread of the virus, general recommendations for individuals and for the risk groups also reviewed.

Current updates on COVID-19 - A review

2020 ◽  
Vol 10 (1) ◽  
pp. 1-8
Author(s):  
Ghotekar D S ◽  
Vishal N Kushare ◽  
Sagar V Ghotekar
Keyword(s):  
World Health Organization ◽  
Common Cold ◽  
Respiratory Diseases ◽  
Gastrointestinal Diseases ◽  
Hubei Province ◽  
World Health ◽  
The World ◽  
The Common ◽  
Novel Coronavirus ◽  
Health Organization

Coronaviruses are a family of viruses that cause illness such as respiratory diseases or gastrointestinal diseases. Respiratory diseases can range from the common cold to more severe diseases. A novel coronavirus outbreak was first documented in Wuhan, Hubei Province, China in December 2019. The World Health Organization (WHO) has declared the coronavirus disease 2019 (COVID-19) a pandemic. A global coordinated effort is needed to stop the further spread of the virus. A novel coronavirus (nCoV) is a new strain that has not been identified in humans previously. Once scientists determine exactly what coronavirus it is, they give it a name (as in the case of COVID-19, the virus causing it is SARS-CoV-2).

Novel Coronavirus 2019 Outbreak: A Global Epidemic

2020 ◽  
Vol 17 (12) ◽  
pp. 1458-1464
Author(s):  
Sweta Kamboj ◽  
Rohit Kamboj ◽  
Shikha Kamboj ◽  
Kumar Guarve ◽  
Rohit Dutt
Keyword(s):  
World Health ◽  
Upper Respiratory Tract ◽  
Global Epidemic ◽  
The Public ◽  
The Government ◽  
Tract Disease ◽  
The 1960S ◽  
Novel Coronavirus ◽  
Health Organization ◽  
The Impact

Background: In the 1960s, the human coronavirus was designated, which is responsible for the upper respiratory tract disease in children. Back in 2003, mainly 5 new coronaviruses were recognized. This study directly pursues to govern knowledge, attitude and practice of viral and droplet infection isolation safeguard among the researchers during the outbreak of the COVID-19. Introduction: Coronavirus is a proteinaceous and infectious pathogen. It is an etiological agent of severe acute respiratory syndrome (SARS) and the Middle East respiratory syndrome (MERS). Coronavirus, appeared in China from the seafood and poultry market last year, which has spread in various countries, and has caused several deaths. Methods: The literature data has been taken from different search platforms like PubMed, Science Direct, Embase, Web of Science, who.int portal and complied. Results: Corona virology study will be more advanced and outstanding in recent years. COVID-19 epidemic is a threatening reminder not solely for one country but all over the universe. Conclusion: In this review article, we encapsulated the pathogenesis, geographical spread of coronavirus worldwide, also discussed the perspective of diagnosis, effective treatment, and primary recommendations by the World Health Organization, and guidelines of the government to slow down the impact of the virus are also optimistic, efficacious and obliging for the public health. However, it will take a prolonged time in the future to overcome this epidemic.

scholarly journals An Overview of the Sociodemographic Considerations of COVID-19 Pandemic

2020 ◽  
pp. 34-39
Author(s):  
Ugbomah Lucy Ohoreorovwori ◽  
Stanley Catherine Nonyelum ◽  
Stanley Princewill Chukwuemeka
Keyword(s):  
World Health ◽  
Natural Immunity ◽  
Infected People ◽  
The Public ◽  
Irregular Migrants ◽  
The Social ◽  
Social Difficulties ◽  
Novel Coronavirus ◽  
Health Organization ◽  
Difficult Situations

Background: Coronavirus disease (COVID-19) is a highly infectious disease caused by a novel coronavirus strain. The virus is believed to spread mainly by respiratory droplets where the infected people breathe, cough or sneeze and expel little droplets of moisture that contain the virus.Older people and people with pre-existing medical conditions are mostly affected. Method: Relevant literatures were reviewed from the internet, electronic and print media, World Health Organization and Center for Disease Control documentation. Results: The coronavirus has brought difficult situations for citizens across the world. Refugees and irregular migrants who find themselves in difficult situations are more vulnerable to the effect of the virus and the social difficulties associated with it. Conclusion: The spread of the virus can be slowed or suppressed through social distancing, natural immunity, and observance of optimal hygiene practice and near compulsory use of face masks, particularly while dealing with the public.

scholarly journals SARS – COV-2 (COVID-19) Pandemic: A Critical Review on Novel Coronavirus Pathogenesis, Clinical Diagnosis and Treatment

2020 ◽  
Vol 10 (3) ◽  
pp. 241-252
Author(s):  
Ruchi Jain ◽  
Nilesh Jain ◽  
Surendra Kumar Jain ◽  
Ram C Dhakar
Keyword(s):  
World Health ◽  
The Novel ◽  
Global Public Health ◽  
Future Studies ◽  
The Public ◽  
The Third ◽  
Treatment And Prevention ◽  
Published Evidence ◽  
Novel Coronavirus ◽  
Health Organization

The 2019-nCoV is officially called SARS-CoV-2 and the disease is named COVID-19. The Novel coronavirus (SARS-CoV-2) caused pneumonia in Wuhan, China in December 2019 is a highly contagious disease. The World Health Organization (WHO) has declared it as a global public health emergency. This is the third serious Coronavirus outbreak in less than 20 years, following SARS in 2002–2003 and MERS in 2012. Currently, the research on novel coronavirus is still in the primary stage. It is currently believed that this deadly Coronavirus strain originated from wild animals at the Huanan market in Wuhan by Bats, snakes and pangolins have been cited as potential carriers. On the basis of current published evidence, we systematically summarize the epidemiology, clinical characteristics, diagnosis, treatment and prevention of COVID-19. This review in the hope of helping the public effectively recognize and deal with the novel coronavirus (SARS-CoV-2) and providing a reference for future studies. Keywords: SARS-CoV-2, COVID-19, Coronavirus, pneumonia, Respiratory infection

scholarly journals Role of nutrients regulation in the immune system in preventing COVID-19 infection: A brief review

2021 ◽  
Vol 13 (2) ◽  
pp. 760-765
Author(s):  
Anamika Chauhan
Keyword(s):  
Immune System ◽  
Age Groups ◽  
World Health ◽  
The Novel ◽  
Beneficial Effects ◽  
Coronavirus Infection ◽  
The Common ◽  
Novel Coronavirus ◽  
Health Organization

This review aimed to focus on using foods to boost immunity against COVID-19 in all age groups. In human, coronavirus causes the common cold, severe acute respiratory syndrome (SARS), and a major threat to public health. The novel coronavirus was declared a pandemic by the World Health Organization due to its rapid infectivity. COVID-19 infection is most probably reported in people with low immunity response. The nutrients, which show beneficial effects on the immune system, are called immune nutrients and diet is called immune diet. A healthy diet can reduce the risk of infection of COVID-19 and can prevent disease. Nutritional food intake is also necessary for people with chronic illness, obese persons, diabetes, cardiovascular disease, cognitive dysfunction like anxiety and depression. All nutrients are essential for maintaining immunity and providing appropriate amounts of protein, fat, carbohydrate, vitamins, and minerals for the surveillance mode of keeping us from getting sick. The use of plenty of water, minerals such as micronutrients, zinc, copper, selenium, iron, magnesium, food rich in vitamins, and a good lifestyle can promote health and overwhelm this coronavirus infection.

scholarly journals Overview of coronavirus - Understanding origin, pathogenesis, clinical features & diagnostic approach to COVID-19 in Indian scenario

2020 ◽  
Vol 8 (S1) ◽  
pp. 41-52
Author(s):  
Bilolikar AK ◽  
Reddy SG ◽  
Banerjee J ◽  
Fatima R ◽  
Poonam AR
Keyword(s):  
Clinical Features ◽  
Close Contact ◽  
Risk Groups ◽  
Laboratory Diagnosis ◽  
World Health ◽  
Enzyme Linked Immunosorbent Assay ◽  
Alveolar Type ◽  
Protein Receptor ◽  
Novel Coronavirus ◽  
Health Organization

In early December 2019, an outbreak of novel coronavirus (2019-nCoV) or the severe acute respiratory syndrome corona virus 2 (SARS-CoV-2) as it is now called, occurred in Wuhan City, Hubei Province, China. On January 30, 2020 the World Health Organization declared the outbreak as a Public Health Emergency of International Concern. Vaccines to prevent human coronavirus infections are not yet available. Coronavirus disease 2019 (COVID-19) spreads primarily when people are in close contact with small droplets produced by an infected person, identified as “super spreaders”. COVID-19 can be fatal among high-risk groups patients >60 yr. The envelope spike “S” protein receptor binding domain of SARS-CoV-2 use host receptor angiotensin-converting enzyme 2 (ACE2) to enter the cells of airway epithelium and alveolar type 2 (AT2) pneumocytes, and pulmonary cells. The most common clinical features are fever (80-90%), cough (60-80%) and breathlessness (18-46%). The other symptoms include myalgia, sore throat, loss of taste and smell, headache, nausea, vomiting and diarrhoea. Infection control practices to be followed stringently by Health Care Workers (HCW). Standard precautions to be maintained. Specimen to be packed in triple container packing. Cold temperature to be maintained during transport and storage. Laboratory tests of COVID-19 are broadly categorized into two methods: (1) Nucleic acid based assay: RT-PCR, TrueNAT, CBNAAT & (2) Immunoassay: Can be broadly divided into 2 types: Antigen based assay: Rapid antigen test, Antibody based assay: enzyme-linked immunosorbent assay (ELISA). Keywords: coronavirus; COVID-19; laboratory diagnosis; SARS-CoV-2

Novel Coronavirus in India Outbreaks around World: A Statistical Analysis of Odisha, India & World

Coronaviruses ◽  
2020 ◽  
Vol 01 ◽  
Author(s):  
Debabrata Singh ◽  
Suman Sekhar Sarangi ◽  
Milu Acharya ◽  
Surjeet Sahoo ◽  
Shakti Ketan Prusty ◽  
...  
Keyword(s):  
Research Work ◽  
World Health ◽  
Swine Flu ◽  
Protective Measures ◽  
The Public ◽  
The World ◽  
Rate Of Recovery ◽  
The Government ◽  
Novel Coronavirus ◽  
Health Organization

Background: The Public Health Emergency of International Concern by the World Health Organization (WHO) declared novel Coronavirus (nCoV-2019) outbreaks in 2019 and is pandemic. Methods: This research work made an analysis of the nCoV-2019 outbreak in India solely based on a mathematical model. Results: The historical epidemics in the world are plague, AIDS, Swine flu, ebola, zika virus, Black Death and SARS. Considering the model used for SARS 2003, the present research on Covid-2019 estimates characteristics of rate of infectious (I) and rate of recovery(R) which leads to estimation the I and R leads to predict the number of infectious and recovery. Through ruling out the unpredictable, unreasonable data, the model predicts that the number of the cumulative 2019-nCoV cases may reach from 3398458(mid of May) to 15165863, with a peak of the unrecovered infective (2461434-15165863) occurring in late April to late July. In this paper we predicate how the confirmed infected cases would rapidly decrease until late March to July in India. We also focus how the Government of Odisha (a state of India) creates a history in the protective measures of Covid-19. Conclusion: The growing infected cases may get reduced by 70-79% by strong anti-epidemic measures. The enforcement of shutdown, lockdown, awareness, and improvement of medical and health care could also lead to about one-half transmission decrease and constructively abridge the duration of the 2019 n-CoV.

scholarly journals Impact of lockdown measures in abating the COVID-19 pandemic: Lessons from India’s phased approach

2020 ◽  
Vol 30 (Supplement_5) ◽  
Author(s):  
R Singh ◽  
K Sharma
Keyword(s):  
Public Health ◽  
World Health ◽  
The Public ◽  
Daily Data ◽  
Travel Restrictions ◽  
Community Transmission ◽  
The Government ◽  
Novel Coronavirus ◽  
Health Organization ◽  
The Impact

Abstract Background World Health Organization (WHO) declared that the outbreak of novel coronavirus (2019-nCoV) constituted a Public Health Emergency of International Concern (PHEIC) on 30 January 2020 and characterized the novel coronavirus disease (COVID-19) as a pandemic on 11 March 2020. India enacted such measures early on for effective mitigation and suppression to reduce community transmission, including an onerous national lockdown. The impact of the health system governance is quite apparent among all stakeholders including the public in such emergency contexts. Methods We compiled the daily data on the number of COVID-19 cases, recoveries and deaths from January 30th until June 16th, 2020. Different stages were categorized from post PHEIC declaration (pre-lockdown) phase to lockdown phases and unlocking phase as implemented. The several measures adopted by the national government were structured in four broad categories as Governance and socioeconomic, travel restrictions, lockdown and public health measures. These measures were compared during each phase. Results It was revealed that while the cases are rising the phased restrictions has helped in delaying the peak and remarkably interrupted the rate of transmission. The national average doubling rate was 3 days at the beginning which improved to 22 days. The basic reproduction number remained close to 1 during the last week of lockdown. However, the initial interruption of needed aid and technical support had negative social and economic impacts on the affected population. Conclusions As the situation abates following the measures adopted by the government, an articulate strategy of unlocking through increased testing and prompt isolation needs to be developed for more effective reduction and protecting the livelihoods allowing to further relax the lockdown measures. Key messages There is need for the local government to consider a strategic easing of the lockdown for protecting the rights of the most affected population. As the transmission rates are low, the easing of lockdown can be benefited from improved testing and prompt isolation.

scholarly journals Tackling the COVID-19 Pandemic- A Review

2021 ◽  
Vol 29 (2) ◽  
pp. 175-186
Author(s):  
CC Nganwuchu ◽  
K Habas ◽  
N Mohammed ◽  
M Osei Wusuansa ◽  
D Makanjuola ◽  
...  
Keyword(s):  
Drug Repurposing ◽  
Health Impact ◽  
Diagnostic Methods ◽  
World Health ◽  
Personal Hygiene ◽  
Diagnostic Tools ◽  
Wide Range ◽  
The World ◽  
Novel Coronavirus ◽  
Health Organization

Since December 2019, a new type of coronavirus called novel coronavirus (2019-nCoV, or COVID-19) was identified in Wuhan, China and on March 11, 2020, the World Health Organization (WHO) has declared the novel coronavirus (COVID-19) outbreak a global pandemic. With more than 101,797,158 confirmed cases, resulting in 3,451,354 deaths as of May 21, 2021, the world faces an unprecedented economic, social, and health impact. The clinical spectrum of COVID-19 has a wide range of manifestations, ranging from an asymptomatic state or mild respiratory symptoms to severe viral pneumonia and acute respiratory distress syndrome. Several diagnostic methods are currently available for detecting the coronavirus in clinical, research, and public health laboratories. Some tests detect the infection directly by detecting the viral RNA using real time reverse transcriptase polymerase chain reaction (RT-PCR) and other tests detect the infection indirectly by detecting the host antibodies. Additional techniques are using medical imaging diagnostic tools such as X-ray and computed tomography (CT). Various approaches have been employed in the development of COVID-19 therapies. Some of these approaches use drug repurposing (e.g. Remdesivir and Dexamethasone) and combinational therapy (e.g. Lopinavir/Ritonavir), whilst others aim to develop anti-viral vaccines (e.g. mRNA and antibody). Additionally, health experts integrate data sharing, provide with guidelines and advice to minimize the effects of the pandemic. These guidelines include wearing masks, avoiding direct contact with infectious people, respiratory and personal hygiene. Taken together, an extensive knowledge on transmission mechanisms, clinical spectrums, specific diagnostics methods, host-virus interactions are required to tackle this pandemic. J. Bio-Sci. 29(2): 175-186, 2021 (December)

scholarly journals COVID-19 Mimicking Acute Colitis

2021 ◽  
Vol 96 (2) ◽  
pp. 143-146
Author(s):  
Jaeseok Park ◽  
Jaekwon Jung ◽  
Hyunsoo Kim ◽  
Changkeun Park ◽  
Daejin Kim ◽  
...  
Keyword(s):  
Severe Acute Respiratory Syndrome ◽  
World Health Organization ◽  
Clinical Picture ◽  
Hubei Province ◽  
World Health ◽  
Acute Colitis ◽  
The World ◽  
The Common ◽  
Novel Coronavirus ◽  
Health Organization

On 11 February, 2020, the World Health Organization announced that COVID-19 was a novel coronavirus disease first detected in Wuhan, Hubei Province, China. COVID-19 is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The complete clinical picture is not fully known. Illness ranges from mild to fatal. The common symptoms include fever, cough, and dyspnea usually developing 2-14 days after exposure. However, diarrhea was present in a few patients with COVID-19. We report a case of COVID-19 mimicking acute colitis.

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