Indonesian indigenous plants as a source of antioxidants to treat gastrointestinal
disorders

Gastrointestinal disorders are the most common illnesses that affect people nowadays. Its prevalence and incidence have increased over the last decades. The majority of the people in Indonesia are still using indigenous plants as medicine to treat these infections or diseases. This study was aimed to determine the potential of Indonesian indigenous plants in treating gastrointestinal disorders. The plants were inventoried through searching articles such as Google Scholar, PubMed, ScienceDirect and Indonesian medicinal plants books. The keyword search term used was “gastrointestinal,” “Indonesian,” “medicinal plants,” “antioxidant activity,” and “phenolic compound,”. A total of fifty-one species of indigenous Indonesian plants of 32 families were recorded as being used by the Indonesian population to treat gastrointestinal disorders. Gastrointestinal disorders that heavily utilize indigenous plants are diarrhoea, constipation, gastric ulcer and gastritis. Indonesian indigenous plants containing bioactive compounds such as alkaloids, flavonoids, saponins, tannins, steroids, terpenoids and phenolics that can serve as a source of antioxidants to treat gastrointestinal disorders. There were five Indonesian indigenous plants with the most potential as a source of antioxidants to cope with gastrointestinal disorders: Zingiber officinale L, Annona muricata, Phyllanthus niruri, Curcuma longa and Curcuma xanthorrizha.

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Ethnopharmacological Assessment of Medicinal Plants Used against Livestock Infections by the People Living around Indus River

BioMed Research International ◽

10.1155/2014/616858 ◽

2014 ◽

Vol 2014 ◽

pp. 1-14 ◽

Cited By ~ 8

Author(s):

Sakina Mussarat ◽

Rahila Amber ◽

Akash Tariq ◽

Muhammad Adnan ◽

Naser M. AbdElsalam ◽

...

Keyword(s):

Medicinal Plants ◽

Curcuma Longa ◽

Zingiber Officinale ◽

Punica Granatum ◽

Preference Ranking ◽

Conservation Strategies ◽

Melia Azedarach ◽

Withania Coagulans ◽

The People ◽

Preferred Species

The present study was aimed to document detailed ethnopharmacological knowledge of medicinal plants against livestock infections of an unexplored remote region of Pakistan. Semistructured questionnaires were used for data collection. Total 43 plants belonging to 26 families were found to be used in ethnoveterinary practices. Seeds (29%) were found to be the most frequent plant part used followed by leaves (22%). Ethnoveterinary recipes were mostly prepared in the form of decoction and powdering. Informant consensus factor (Fic) results revealed high consensus for gastrointestinal (0.81), mastitis (0.82), and dermatological infections (0.80).Curcuma longaranked first with highest fidelity level (FL) value (66%) followed byTrachyspermum ammithat ranked second (58%). Preference ranking (PR) results showed thatZingiber officinale,Punica granatum,Triticum aestivum,Gossypium hirsutum, andWithania coagulanswere the most preferred species for the treatment of diarrhea. Direct matrix ranking (DMR) results showed thatMorus alba,Melia azedarach,Withania coagulans,Cassia fistula,Azadirachta indica, andTamarix aphyllawere the multipurpose species of the region. We invite the attention of pharmacologists and chemists for further exploration of plants having high Fic, FL, and PR values in the present study. Conservation strategies should be adopted for the protection of multipurpose plant species.

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Medicinal Plant by Batak Toba Medicinal plants used by the Batak Toba Tribe in Peadundung Village, North Sumatra, Indonesia

Biodiversitas Journal of Biological Diversity ◽

10.13057/biodiv/d200230 ◽

2019 ◽

Vol 20 (2) ◽

pp. 510-525 ◽

Cited By ~ 1

Author(s):

MARINA SILALAHI ◽

NISYAWATI NISYAWATI ◽

DINGSE PANDIANGAN

Keyword(s):

Medicinal Plants ◽

Curcuma Longa ◽

Zingiber Officinale ◽

Single Species ◽

Psidium Guajava ◽

Piper Betle ◽

Structured Interviews ◽

Medicinal Species ◽

Eurycoma Longifolia ◽

North Sumatra

Abstract. Silalahi M, Nisyawati, Pandiangan D. 2019. Medicinal plants used by the Batak Toba Tribe in Peadundung Village, North Sumatra, Indonesia. Biodiversitas 20: 510-525. Research of the medicinal plants by the Toba Batak ethnic has limited, even though the globalization and modernization resulted to degradation of the local knowledge. The objectives of this study were (i) documentation of medicinal plants used in the traditional therapies by the Batak Toba tribe of Peadundung Village, North Sumatra, Indonesia, and (ii) analysing the data by quantitative ethnobotanical tools such as use value (UV), cultural significance index (CSI), relative frequency of citation (RCF) and informant consensus factor (ICF) to determine the cultural importance of medicinal plants in order to develop a tool for their conservation. Semi-structured interviews with 41 identified respondents was the methodology employed for qualitative data collection. A total of 149 medicinal species of plants, belonging to 131 genera and 55 families, were recorded in the study which are used in the treatment of 21 categories of ailments. Plants with the highest UV were Eurycoma longifolia (UV=3.44), Curcuma longa (UV=2.67) and Zingiber officinale (UV=2.60). Eight species, namely Curcuma longa, Eurycoma longifolia, Allium cepa, Psidium guajava, Aleurites moluccanus, Piper betle, Citrus hystrix and Uncaria gambir were found to be having the highest RCF value of 1.00. Eurycoma longifolia (CSI=126), Curcuma longa (CSI=112) and Zingiber officinale (CSI = 105) emerged as the culturally most significant medicinal plants. Thrush and aphrodisiac use categories received the highest ICF of 1.00 each because the informants agreed of using only a single species for each of these categories. Eurycoma longifolia was used as an aphrodisiac whereas Averrhoa carambola was used against thrush. All these important and significant plants suffer the greatest harvesting pressure, hence their conservation should be given priority.

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Preclinical Antihyperlipidemic Effect of Herbalism against Lipid Elevating Agents: A Review

Biomedical & Pharmacology Journal ◽

10.13005/bpj/2044 ◽

2020 ◽

Vol 13 (4) ◽

pp. 1695-1707

Author(s):

Bushra Ansari ◽

Monika Singh ◽

Shalini Sharma ◽

Bushra Choudhary ◽

Mohseen Mohseen

Keyword(s):

Medicinal Plants ◽

Curcuma Longa ◽

Low Density Lipoprotein ◽

Density Lipoprotein ◽

Zingiber Officinale ◽

Poloxamer 407 ◽

Low Density ◽

Garcinia Cambogia

Abnormal increase in the level of more than any one of the lipoproteins such as triglycerides, cholesterol, LDL or VLDL in the bloodstream can be defined as hyperlipidemia. It is the greatest world is often overused so, use “the most significant” instead of the greatestrisk factor of coronary heart attack and stroke.This review emphasizes on some herbal medicinal plants with their extracts, including Glycyrrhiza glabra,Legenaria siceraria,Medicago sativa,Curcuma longa,Curatella americana, Glycine max, Hibisus rosa-sinesis, Hibisus sabdariffa, Cinnamomum tamala, Withania somnifera, Cassia auriculata, Cynaras scolymus, Eugenia jambolana, Adenanthera pavonia, Garcinia cambogia, Terminalia chebula, Ixora coccinea, Carica papaya, Lycimum barbarum, Bauhinia purpurea, Syzygium alternifolium, Vitex negundo, Piper longa, Moringa oleifera, Zingiber officinale, Trigonella foenum graecum, Carum carvi, Gloriosasuperba, Ficus infectoria, Ficus glomerata for anti-hyperlipidemic potential. Decrease in the levels of these lipoproteins like, triglycerides (TG), Total cholesterol (TC), Very low density lipoprotein (VLDL) and low-density lipoprotein (LDL)includes some mechanisms actions of these medicinal plants observed in triton-x, cholesterol, high fat diet, Poloxamer-407, Dexamethasone and alloxan-induced in-vivo and in-vitro models. Accordingly, this review provides numerous evidenceswhichindicatethat these medicinal plants can be usedfor treating and preventinghyperlipidemia and related complications.

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Review of Antiviral Medicinal Plants used in Taraba State Nigeria: A Possible Source for COVID-19 Drug Discovery

Journal of Scientific Research in Medical and Biological Sciences ◽

10.47631/jsrmbs.v1i2.50 ◽

2020 ◽

Vol 1 (2) ◽

pp. 1-23

Author(s):

Cletus Anes Ukwubile ◽

Troy Silvia Malgwi ◽

Alexander Ezekiel Angyu ◽

Otalu Otalu ◽

Mathias Simon Bingari

Keyword(s):

Medicinal Plants ◽

Allium Sativum ◽

Viral Infections ◽

Curcuma Longa ◽

Antiviral Agents ◽

Zingiber Officinale ◽

Human Influenza Virus ◽

Infectious Bronchitis ◽

The Usa ◽

Ocimum Tenuiflorum

Purpose: Coronavirus also known as COVID-19 is a viral infection that has been tagged as the greatest pandemic since the existence of humans by the WHO, resulting in the deaths of thousands of people globally; with the USA one of the highest. The full biology of the virus is yet to be known. This study reviews sixteen natural antiviral plants used in Taraba State to manage viral infections locally. Subjects and Methods: Sixteen medicinal plants popularly used as antiviral agents in Taraba State, Nigeria were surveyed based on a field-trip experience with herbal medicine practitioners in the three zones of the state. Plants that were in both zones were counted as the same. The plants that are majorly used for various viral infections are Allium sativum, Zingiber officinale, Camellia sinensis, Hibiscus sabdariffa, Cirus lemon, Azardirachta indica, Ocimum tenuiflorum, Curcuma longa, Haematostaphis barteri, Olea europaea, Melastomastrum capitatum, Astragalus canadensis, Carissa edulis, Spondias venulosa, Vitellaria paradoxa, and Euphorbia hirta. Results: Of the sixteen plants, ten have been reported to have antiviral properties against at least one of these viruses avian or bird flu, human influenza virus, infectious bronchitis virus (a type of coronavirus), herpes virus, hepatitis C virus and HIV. Conclusion: The study revealed that further research on these antiviral plants used traditionally might pave the way for the discovery of potent antiviral drugs against COVID-19.

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Ethnomedicinal Study of Medicinal Plants Used by Mizo Tribes in Champhai District of Mizoram, India.

10.21203/rs.3.rs-1021345/v1 ◽

2021 ◽

Author(s):

TBC Laldingliani ◽

Nurpen Meitei Thangjam ◽

R Zomuanawma ◽

Laldingngheti Bawitlung ◽

Anirban Pal ◽

...

Keyword(s):

Medicinal Plants ◽

Plant Species ◽

Curcuma Longa ◽

Secondary Data ◽

Modern Medicine ◽

Ethnomedicinal Plants ◽

North East ◽

The North ◽

Informant Consensus ◽

The People

Abstract Background Medicinal plants have been used countless times for curing diseases mainly in developing countries. They are easily available with little to no side effects when compared to modern medicine. This manuscript encompasses information on ethnomedicinal plants in Champhai district, located in the North East Region (NER) of India. The region lies within Indo-Burma biodiversity hotspot. This study will be the first quantitative report on the ethnomedicinal plants used by the local tribes of this region. Knowledge of medicinal plants is mostly acquired by word of mouth and the knowledge is dying among the local youths with the prevalence of modern medicine. Hence, there is urgency in deciphering and recording such information. Methods Information was gathered through interviews with 200 informants across 15 villages of the Champhai District. From the data obtained, we calculated the Used Report (UR), Frequency of Citation (FC) and Informant Consensus Factor (Fic) for all the plant species. Secondary data was obtained from scientific databases such as Pubmed, Sci Finder and Science Direct. The scientific name of the plants were matched and arranged in consultation with the working list of all plant species (http://www.theplantlist.org ). Results 93 plant species from 53 families were recorded. The most common families are Euphorbiaceae and Asteraceae with six and five species representatives respectively. Leaves were the most frequently used part of a plant and were usually used in the form of decoction. The plant species with the highest used report (UR) were Curcuma longa L. (136 FC) and Flueggea virosa (126 FC). The main illness categories as per Frequency of citation were Muscle/Bone Problem (0.962 Fic), Gastro-intestinal Disease (0.956 Fic) and Skin Care (0.953 Fic). Conclusion The people of Mizoram living in the Champhai district have an immense knowledge of ethnomedicinal plants. There are no new adverse effects recorded. We observed that there is a scope of scientific validation of 10 plant species for their pharmacological activity and 13 species for the phytochemical characterization or isolation of the phytochemicals. This might pave the path for developing a scientifically validated botanical or lead to semisyntheic derivatives intended for modern medicine.

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ETHNO-BOTANICAL SURVEY OF PLANTS USED IN A RHEUMATOID ARTHRITIS TREATMENT: A CASE STUDY OF JOS IN NIGERIA

Medical Science of Ukraine (MSU) ◽

10.32345/2664-4738.4.2020.6 ◽

2020 ◽

Vol 16 (4) ◽

Author(s):

G.T. Tongshuwar ◽

A.O. Ojetunde ◽

A.F. Oyegoke ◽

T. Oyegoke

Keyword(s):

Rheumatoid Arthritis ◽

Curcuma Longa ◽

Autoimmune Disorder ◽

Zingiber Officinale ◽

Orthodox Medicine ◽

Verbal Form ◽

The People ◽

Long Run ◽

Genetic And Environmental Factors ◽

Synovial Tissues

Relevance. Rheumatoid arthritis (RA) is an autoimmune disorder leading to the inflammation of the joints. This inflammation finds expression in the lining of the synovial tissues causing swellings and severe pains and deterioration of the bone in the long run. This disease's exact etiology is not yet to be ascertained; however, there are claims of the interplay of genetic and environmental factors. RA is one of the diseases ravaging the people of Jos in Nigeria, owing to the high cost of orthodox medicine. Objective. The study was carried out to collect information and find out plants used to treat rheumatoid arthritis in Jos, Nigeria, in addition to the availability of the plant(s). Materials and methods. An electronic-based questionnaire was used to get information from the respondents. Result. Eight species of plants were reported to be used. Garlic (Allium sativum), Ginger (Zingiber officinale), Turmeric (Curcuma longa), and Onion (Allium cepa) were the dominant plants reportedly used. The parts of plants used are the plant bulb and stem. They are reported to be prepared by grinding and herbal mixture; chewing and decoction were not popular. Respondents with this information reported their willingness to share with both family and friends. Conclusion. This study shows the availability of traditional RA treatment and the preservation of verbal form knowledge.

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Keanekaragaman dan Pemanfaatan Tanaman Obat pada Pekarangan di Dumoga Utara, Kabupaten Bolaang Mongondow, Sulawesi Utara

JURNAL BIOS LOGOS ◽

10.35799/jbl.11.2.2021.32017 ◽

2021 ◽

Vol 11 (2) ◽

pp. 82

Author(s):

Dewi Lestari ◽

Roni Koneri ◽

Pience Veralyn Maabuat

Keyword(s):

Medicinal Plants ◽

Sampling Method ◽

Curcuma Longa ◽

Zingiber Officinale ◽

Snowball Sampling ◽

Active Components ◽

Purposive Sampling ◽

Number Of Species ◽

North Sulawesi ◽

The Family

(Article History: Received January 12, 2021; Revised March 8, 2021; Accepted April 7, 2021) ABSTRAKTanaman obat merupakan tanaman yang memiliki komponen aktif dan diyakini oleh masyarakat dapat menyembuhkan penyakit. Penelitian ini bertujuan untuk menganalisis keanekaragaman dan pemanfaatan tanaman obat pada pekarangan di Dumoga Utara, Kabupaten Bolaang Mongondow, Sulawesi Utara. Metode pengambilan sampel menggunakan purposive sampling. Pemilihan responden dilakukan dengan metoda snowball sampling. Hasil penelitian didapatkkan sebanyak 25 famili, yang terdiri dari 46 spesies dan 2691 individu tanaman obat. Famili yang banyak ditemukan jumlah spesies dan individunya adalah Zingeberaceae, merupakan famili yang banyak ditemukan jumlah spesies dan individunya. Spesies yang memiliki kelimpahan tertinggi adalah Sauropus androgynus, kemudian Zingiber officinale dan Curcuma longa. Indek kekayaan, keanekaragaman dan kemerataan spesies tertinggi pada pekarangan Suku Jawa. Bentuk hidup tanaman obat yang paling banyak ditemukan adalah herba dan perdu. Daun merupakan bagian tanaman yang banyak dimanfaatkan untuk tanaman obat dan proses pengolahan umumnya dengan cara direbus. Pemanfaatan tanaman obat pekarangan oleh masyarakat dapat digunakan untuk mengobati 18 jenis penyakit.Kata kunci: Tanaman obat; Zingiberaceae, Sauropus androgynus, herba. ABSTRACTMedicinal plants are plants that have active components and are believed by the community to cure diseases. This study aims to analyze the diversity and utilization of medicinal plants in the yard in North Dumoga, Bolaang Mongondow Regency, North Sulawesi. The sampling method used was purposive sampling. The selection of respondents was carried out using the snowball sampling method. The results of the study were 25 families, consisting of 46 species and 2691 individual medicinal plants. The family with the highest number of species and individuals was Zingeberaceae, which was the family with the highest number of species and individuals. The species with the highest abundance were Sauropus androgynus, then Zingiber officinale and Curcuma longa. The highest index of species richness, diversity and evenness was in the Javanese tribe. The most common forms of medicinal plant life are herbs and shrubs. Leaves are part of a plant that is widely used for medicinal plants and in general processing by boiling. The use of yard medicinal plants by the community can be used to treat 18 types of diseases.Key words: Medicinal plants; Zingiberaceae, Sauropus androgynus, herb.

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The Utilization of Medicinal Plants to Overcome Gastric Disorders by The Dayak Muara Tribe in Kuala Dua Village, Sanggau Regency

JURNAL BIOLOGI TROPIS ◽

10.29303/jbt.v21i2.2638 ◽

2021 ◽

Vol 21 (2) ◽

pp. 416

Author(s):

Fathul Yusro ◽

Yeni Mariani ◽

Evy Wardenaar

Keyword(s):

Medicinal Plants ◽

Curcuma Longa ◽

Centella Asiatica ◽

Zingiber Officinale ◽

Nausea And Vomiting ◽

Use Value ◽

Fidelity Level ◽

Informant Consensus Factor ◽

Informant Consensus ◽

Intestinal Worms

People use medicinal plants to treat various diseases, one of which is gastric disorders. The study aims to analyze the use of medicinal plants to overcome gastric disorders by the Dayak Muara tribe in Kuala Dua Village, Sanggau Regency. The sampling method was purposive sampling, with the number of respondents was 10% of the total number of households in Kuala Dua Village (91 respondents). The information regarding the medicinal plants used by the Dayak Muara tribe to overcome gastric disorders such as diarrhea, intestinal worms, nausea and vomiting, constipation, gastric, flatulence, and stomachache was collected. Furthermore, data obtained analyzed for the use-value (UV), informant consensus factor (ICF), and fidelity level (FL). The Dayak Muara tribe in Kuala Dua village, Kembayan District, has used 17 species of medicinal plants to overcome gastric disorders. Curcuma longa is the plant with a high use value or UV (0.96), followed by Psidium guajava (0.89) and Zingiber officinale (0.45). The highest value of informant consensus factor or ICF includes the diseases category of diarrhea (0.98), gastric, stomachache, nausea, and vomiting, each of which has an ICF value (0.96), constipation (0.94), intestinal worms and flatulence (0.88). The plants with the highest fidelity level (FL) are Allium sativum, Cymbopogon citratus and Centella asiatica for gastric (100), Areca catechu for constipation (100), Moringa oleifera, and Theobroma cacao (100) for stomachache.

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Diversity of medicinal plants utilized by To Manui ethnic of Central Sulawesi, Indonesia

Biodiversitas Journal of Biological Diversity ◽

10.13057/biodiv/d210145 ◽

2020 ◽

Vol 21 (1) ◽

Cited By ~ 1

Author(s):

Nuning Rahmawati ◽

FANIE INDRIAN MUSTOFA ◽

SARI HARYANTI

Keyword(s):

Medicinal Plants ◽

Curcuma Longa ◽

Conservation Status ◽

Traditional Healers ◽

Iucn Red List ◽

Pharmacological Effects ◽

Inclusion Criteria ◽

International Union ◽

The People ◽

Central Sulawesi

Abstract. Rahmawati N, Mustofa FI, Haryanti S. 2020. Diversity of medicinal plants utilized by To Manui ethnic of Central Sulawesi, Indonesia. Biodiversitas 21: 375-392. The present study reports the utilization of medicinal plants as medicines for the treatment of various diseases among the people of To Manui tribe in Central Sulawesi Province of Indonesia. Data collecting was conducted based on purposive random sampling to five selected traditional healers who fulfilled some inclusion criteria. The results showed as of 89 species of medicinal plants distributed in 50 families and 80 genera have been documented to have any pharmacological effects against 37 diseases and illnesses. Curcuma longa L. was determined as the most frequent medicinal plant used by traditional healers in To Manui for treating diabetes mellitus as well as after-birth treatment. However, conservation of some medicinal plants needs to be initiated in the study area especially Alstonia scholaris (L.) R. Br. as it is recognized in International Union for Conservation of Nature (IUCN) Red List as Least Concern (LC) of conservation status.

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Evaluation of anti-dermatophytic activity of medicinal plants derived products

International Journal of Research in Dermatology ◽

10.18203/issn.2455-4529.intjresdermatol20205590 ◽

2020 ◽

Vol 7 (1) ◽

pp. 28

Author(s):

Anu Gupta ◽

Alisha . ◽

Sandeep Kaur ◽

Prabhjot Kaur Gill

Keyword(s):

Medicinal Plants ◽

Azadirachta Indica ◽

Allium Sativum ◽

Curcuma Longa ◽

Cocos Nucifera ◽

Zingiber Officinale ◽

Melaleuca Alternifolia ◽

Keratinized Tissue ◽

Dermatophyte Species ◽

Citrus Limonum

Background: Dermatophytes are a group of closely related fungi which are able to invade the keratinized tissue skin, hair and nail. In this study different medicinal plants like Melaleuca alternifolia, Zingiber officinale, Allium sativum, Azadirachta indica, Citrus limonum, Curcuma longa, Cocos nucifera were used as antifungal agent against different dermatophyte species.Methods: A hospital-based study consisting of 320 patients clinically diagnosed having dermatophytic infection who reported to the Dermatology outpatient department (OPD), Adesh medical college, Bathinda was conducted for the period of 2 years. Socio-demographic and clinical information was collected and sample was taken from the edge of infected area which was then collected in 2 ml of Eppendorf. Extracts of medicinal plants were then explored against dermatophyte. The data was evaluated using appropriate statistical method.Results: All dermatophyte species were found sensitive for Melaleuca alternifolia, Zingiber officinale and Allium sativum. These medicinal plants showed very good results as antifungal against dermatophytes while Azadirachta indica and Citrus limonum were moderate sensitive and Curcuma longa and Cocos nucifera did not show any zone of inhibition around the well.Conclusions: This research provides a scientific validation for the use of these medicinal plants in the treatment of dermatophytic infection and could be used in future for dermatophytic infection and other skin infection.

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