scholarly journals To determine the frequency of Hepatitis C Infection in patients with Ischemic Stroke at CMCH Larkana.

2020 ◽  
Vol 27 (01) ◽  
pp. 162-165
Author(s):  
Hakim Ali Abro ◽  
Azizullah Jalbani ◽  
Chandur Lal ◽  
Sheeraz Ali ◽  
Sultan Ahmed Chandio ◽  
...  

Objectives: To determine the frequency of Hepatitis C infection in patients with ischemic Stroke at CMCH Larkana. Study Design: Cross-sectional study. Setting: Medical wards of Shaheed Mohtarma Benazir Bhutto Medical University Larkana. Period: From January 2018 to December 2018. Material & Methods: This study was conducted on 125 diagnosed ischemic stroke patient with age >18 years or both genders. Patients with sudden history of partial or complete weakness of half the body persisting for more than 24 hours and clinical examination supporting reduced power and presence of focal sign and CT brain showing hypodense area in respected blood supply. Patients were considered suffering from Hepatitis C who were reactive to anti HCV on second generation ELISA. Results: We surveyed 125 patients admitted with clinical diagnosis of ischemic stroke after exclusion criteria with mean age of 54.53 ± 10.994. In this study male were 51.2% and female were 48.8%. About 40 (32% patients were anti HCV reactive. Conclusion: It is revealed that HCV infection significantly increased the risk of stroke.

2015 ◽  
Vol 22 (10) ◽  
pp. 1278-1283
Author(s):  
Shabnam Naveed ◽  
Syed Masroor Ahmed ◽  
Zeeshan Ali ◽  
Romana Awan ◽  
Humaira Zakir ◽  
...  

Objectives: To determine the prevalence of Hepatitis C virus infection in Type IIDiabetes Mellitus patients and its associated risk factors in our population. Duration and Placeof Study: Study was conducted in Jinnah Post graduate Medical Centre, Karachi betweenDecember 2013 to December 2014.Study Design: It is a Cross-sectional study. Data collectionand Results: Data was collected from registered diabetic patients, 355 diagnosed Type IIdiabetes mellitus patients including 128(36.1%) males and 227(63.9%) females were selectedand their Hepatitis C screening was done by ICT method. The bio-data of the patients, history andduration of diabetes mellitus, history of blood transfusion, previous surgery, accidents, shavingfrom barber, tattooing, nose piercing, acupuncture,insulin use were recorded on a proforma.Out of the 355 diabetes mellituspatients tested, 33 were positive for anti-HCV antibodies givinga prevalence of 9.3%. Conclusion:There is increased prevalence of HCV infectionin diabeticpatients when compared with general prevalence of HCV in Pakistan.


2021 ◽  
Author(s):  
Shima Salehi ◽  
Rozita Hosseini Shamsabadi ◽  
Hassan Otukesh ◽  
Reza Shiari ◽  
Monir Sharafi

Abstract Background: Lupus is an inflammatory and autoimmune disease that involves various tissues and organs of the body. Identification of diagnostic elements to rapid identification of seronegative lupus cases is very important in order to prevent morbidity and progression of disease. This study aimed to compare clinical and laboratory findings of seropositive cases with seronegative lupus patients. Methods: This cross-sectional analytic study was performed on 43 children (17 seronegative and 26 seropositive) with lupus who were admitted to Ali Asghar Hospital during 2007-2017. Seropositive patients had anti-nuclear antibody (ANA) titration >1/80, while seronegative patients had ANA titration <1/80 (at the time of disease diagnosis). Clinical and laboratory findings were compared between two groups.Results: Serositis in patients with ANA- was significantly higher than ANA+ (41.17% vs. 23.07%; p = 0.042). ANA- group had higher autoimmune disease history than ANA+ group (42.85% vs. 15.0%; p = 0.041). The family history of the disease in the ANA- group was greater than ANA+ group (50% vs. 23.52%). The percentage of hypertensive patients in ANA- group was higher than ANA+ group (52.94% vs. 26.92%; p = 0.037). Neurologic symptoms in ANA+ and ANA- groups were 38.46% and 17.64%, respectively (p = 0.043). The frequency of patients with thrombocytopenia in ANA+ group was significantly greater than ANA- group (32% vs. 12.5%; p=0.041). There was no significant difference in other clinical and laboratory findings between two groups. Conclusion: Seronegative lupus patients had higher percentage of musculoskeletal symptoms, autoimmune disease history, familial history of disease, and hypertension, while neurological and thrombocytopenia symptoms were higher in seropositive patients compared to seronegative cases. Therefore, evaluation of these factors can be helpful to diagnosis of seronegative patients.


Author(s):  
Md Ali Kawsar ◽  
Marina Akhtar ◽  
Md Ahsan Habib ◽  
Zafrina Islam ◽  
Md Nurul Islam

Background: Oral hygiene maintenance is difficult for patients who are receiving fixed orthodontic treatment. Objective: The aim of the study was to find out deterioration of oral hygiene status during treatment of fixed orthodontic appliances in the Department of Orthodontics in BSMMU. Methodology: This cross sectional study was carried out in the Department of Orthodontics at Bang-  abandhu Sheikh Mujib Medical University, Dhaka from July 2013 to July 2014. All the patients taking treatment with fixed orthodontic appliances for more than 6 months were included as study population. During treatment in the OPD all the information of the patients’ oral hygiene maintenance like brush-  ing, dental floss use, use of mouthwash, and history of sugar consumption, taking sticky food were recorded.  The  Orthodontic  Plaque  Index  (OPI)  was  calculated  and  recorded.  In  addition  to  that frequency of brushing, type of tooth brush, technique of brushing and inter dental brush were also considered. Result: A total number of 100 patients were studied. Mean OPI was 81.78 (22.97). Mean value of OPI was 86.35 (13.27) among patients who brushed their teeth once a day but it was decreased gradually as the  patients  increased  frequency  of  toothbrush  use  per  day  and  became  85.74  (±26.12)  among  the patients who brushed their teeth thrice a day. Mean value of OPI was 81.98 (±23.27) who did not use dental floss and 75.00 (±7.00) who used dental floss once a day. Mean value of OPI was 84.65 (±23.10) who used inter dental brush irregularly but 35.00 (±0.00) who used it thrice a day. Mean value of OPI was 85.70 (±22.43) who did not use mouth wash whereas it reduced to 46.00 (±0.00) among them who used mouth wash thrice a day.  Conclusion: All the indexes of oral hygiene are increased in patients treated with fixed orthodontic appliances in the Department of Orthodontics in BSMMU. Ban J Orthod & Dentofac Orthop, April 2017; Vol-7 (1-2), P.16-19


2021 ◽  
Vol 9 (2) ◽  
pp. 93
Author(s):  
Astrid Kristina Kardani ◽  
Ninik Asmaningsih Soemyarso ◽  
Jusli Aras Aras ◽  
Risky Vitria Prasetyo ◽  
Mohammad Sjaifullah Noer

Chronic kidney disease (CKD) is a serious health problem in children, with increasing morbidity and mortality rates throughout the world. Children with CKD tend to experience magnesium (Mg) defi ciency that can stimulate an infl ammatory response in the body. One of the infl ammatory responses is an increase of Interleukin-6 (IL-6).  Study to analyze the correlation between Mg and IL-6 in pre-dialysis CKD children. The methods a cross sectional study was conducted in Dr Soetomo General Academic Hospital from November 2018 to April 2019. Children with pre-dialyis CKD were included in this study. Variables of serum Mg level (mg/dL) and infl ammatory marker (IL-6) were measured from the blood and analyzed by ELISA method. The correlation between Mg and IL-6 was analyzed with Spearman’s correlation test with p <0.05.  Result a total of 47 children (27 boys vs 20 girls) between 3 months to 18 years old, with pre-dialysis CKD and no history of magnesium supplementation were included. The primary disease that causes of CKD were lupus nephritis (38.3%), nephrotic syndrome (23.4%), urologic disorder (23.4%),  tubulopathy (10.6%) and others (4.3%). The average IL-6 level was 55.42±43.04 pg/dL and Mg level was 2.06±1.54 mg/dL. There were no signifi cant correlation between IL-6 level and Mg level with staging of CKD and duration of illness (p>0.05), but there was a signifi cant correlation between serum Mg level and IL-6 level (r=-0.748; p<0.001). Magnesium levels have a signifi cant inverse correlation with IL-6 levels in pre-dialysis CKD children. The lower the Mg levels in the blood, the higher IL-6 levels and vice versa. 


Author(s):  
Bushra . ◽  
Ambreen Ghori ◽  
Azra Ahmed ◽  
Najma Dalwani ◽  
Mushtaque Ali Shah ◽  
...  

Background: Pregnancy is a very crucial time in a woman’s life. In this period of time, not only multiple physiological alterations effect the usual health status but also makes women more vulnerable to contract infection and face negative sequalae. Hepatitis C, a blood borne viral infection serve the similar fate when encountered by pregnant ladies. This study is based on exploring the prevalence of the Hepatitis C virus seropositivity among pregnant population. Moreover, we also evaluated the major risk factors leading to the infection in these mothers. Besides this, infected mothers were studied for their pregnancy outcomes.Methods: In this study 114 pregnant females were observed for this cross-sectional study. It was conducted in Gynecology Unit- 1, Liaquat University Hospital Hyderabad, for the period of January 2017 to July 2017. Chi square test was applied for statistical analysis on SPSS version 16. The criteria for enrollment in the study was set to be a pregnant lady belonging to age group 20-35 years; having singleton pregnancy; was a booked case at the hospital with compliant to antenatal follow ups; admitted to the labor room for delivery. All the non-pregnant ladies, whom had co morbid conditions such as hypertension or diabetes or had infected with hepatitis B or D were excluded from the study. Furthermore, pregnant ladies with multiple gestion or those who were either diagnosed of hepatitis C prior to conceive or had a previous history of hepatitis C were also excluded.Results: Present study revealed that out of 114, 10(8.8%) pregnant ladies were found seropositive for Hepatitis C virus. Prior history for transfusion of blood was the Foremost risk factor discovered, with 60.5% women reported this. History of surgery was the 2nd commonest factor and 43.9% had this in their medical records. On the other hand, only 8.8% women gave the history for previous evacuation. While observing pregnancy outcomes, we found 48.2% neonates had low birth weight, 41.2% were born preterm and 21.1% had low APGAR score.Conclusions: In a nutshell hepatitis c is prevalent in the pregnant population of this region and showing its effects in the form of compromised pregnancies. History of blood transfusion and previous surgery were found to be chief risk factors in the study.


2014 ◽  
Vol 43 (1) ◽  
pp. 17-20
Author(s):  
Makhan Lal Paul ◽  
Monoj Sinha ◽  
Ahsan Habib ◽  
Lubna Khondker ◽  
Md Mahabubur Rahman ◽  
...  

The causes of polyneuropathy are many and it is important to identify them, as some of them, especially the inflammatory types are treatable. To explore the different etiological factors of polyneuropathy, this cross sectional study was carried out in the department of Neurology, Bangabandhu Sheikh Mujib Medical University (BSMMU), Shahbag, Dhaka. Data were collected by taking medical history and clinical examination and subsequent laboratory investigations. A total of 60 subjects were included in this study and mean age of the entire patient was 42.25 year. Out of all respondents, 83.3% had muscle weakness, similar number had problems with object handling, 66.3% had muscle cramp, 63.3% had impaired standing or gait, 55.0% had distal paraesthesia, 41.7% had burning feet, 8.3% had restless legs and 5.0% had stiffness. Out of all patients of polyneuropathy, 33.3% had diabetic neuropathy, 11.7% had Guillain-Barré syndrome, 10.0% had chronic inflammatory demyelinating polyneuropathy, similar number had unknown etiology, 6.7% had charcot-marry-tooth disease disease, 6.7% had renal failure, 5.0% had leprosy, Vitamin B 12 deficiency and chronic liver disease of each, 3.3% had history of isoniazide drug intake and similar had systemic lupus erythromatosus. We conclude that, polyneuropathy has wide variety of etiological factors. Among them, diabetes is the most common factor. Further large controlled study is needed to establish the etiological pattern in the context of Bangladesh. DOI: http://dx.doi.org/10.3329/bmj.v43i1.21371 Bangladesh Med J. 2014 January; 43 (1): 17-20


2019 ◽  
Vol 26 (02) ◽  
Author(s):  
Abdul Aziz Sahto ◽  
Amir Shahzad ◽  
Ruqayya

Objectives: The aim behind this study was assess the frequency of ischemic and hemorrhagic stroke and associated risk factors in patients with hypertension. Study Design: Cross sectional study. Period: One year. Setting: Department of Medicine People’s Medical University, Shaheed Benazeerabad. Material and Methods: This study was a hospital based study in which sampling was done through a purposive sampling technique. A total of 160 patients admitted with stroke were included in our study. After taking informed consent patient’s relevant history and examination were carried out. CT-Scan was done to confirm and different between ischemic and hemorrhagic stroke.SPSS version 17.0 was used to analyze the collected data. Results: Ischemic stroke was observed in 105(66%) patients and 55(34%) were suffered hemorrhagic stroke. Hypertension was 100% in both types of storks in ischemic stroke and hemorrhagic stroke.Rate of diabetes mellitus, dyslipidemia and smoking were significantly high in hemorrhagic stroke than ischemic stroke (p<0.01). Conclusion: We found a high prevalence of ischemic stroke than hemorrhagic stroke in our population. Among associated factors gender, hypertension, dyslipidemia, diabetes and smoking were prevalent in both ischemic and hemorrhagic stroke patients.


2021 ◽  
Vol 11 (3) ◽  
pp. 9-13
Author(s):  
Nourollah Ramroodi ◽  
Seyed Mehdi Hashemi ◽  
Mehrdad Ramroudi

Objective: The aim of the present study was to investigate the epidemiological pattern of factors associated with ischemic stroke among patients under 50 years old. Methods: The present cross-sectional study was performed on 197 Stroke patients. Individuals with confirmed ischemic stroke based on of CT scan were included in the study. Demographic information included age, sex, history of smoking, place of residence, season of disease incidence, history of contraceptive use in women, history of hypertension, having high blood pressure at the onset of diabetes, hyperlipidemia, heart disease and patient weight. Finally, the collected data was analyzed using SPSS ver. 22. Results: The mean age of participants was 40.18 years. The mean weight, height, body mass index (BMI) were 79.83, 168.63, and 28.12, respectively. A total of 60.4% of the participants were male and 39.6% were female. Moreover, 66.9% were urban residents, 38.6% had complications in winter, 67% were smokers, and 50% used contraceptives. The history of hypertension, diabetes, hyperlipidemia, and heart disease was seen in 69%, 49.7, 66%, and 73.6% of cases, respectively. Also, 53.8% of patients had high blood pressure upon admission. Conclusion: The present study showed that a history of heart disease and a history of hypertension in the past and nicotine use are very common in people with stroke. Considering the above mentioned epidemiological factors, it is recommended to prioritize the mentioned factors when identifying new cases


Background: Today, the use of dental radiography equipment in dental centers has increased due to its high application in the diagnosis of dental diseases. As a result, concerns are increasing regarding repeated exposure to this low dose level of radiation. Therefore, the knowledge and practice of dentists about radiation protection are essential for themselves and the patients. This study aimed to assess the knowledge and practice of dentists about radiation protection. Materials and Methods: This cross-sectional study was performed based on a questionnaire in several cities of Iran. The first part of the questionnaire included such information as gender, years of work experience, and participation in radiation protection workshops. The second, third, and fourth sections consisted of questions on radiobiology, radiation protection, and performance, respectively. Results: In this study, 94 dentists participated, and the mean scores of dentists (out of 5 points) for radiobiology knowledge, radiation protection knowledge, and performance were obtained at 2.66±1.1, 2.80±1.01, and 2.87±1.37, respectively. The results of Pearson analysis showed that general knowledge had a significant relationship with performance (P=0.014). There was also a significant relationship between the history of participation in radiation protection workshops and performance (P=0.01). Conclusion: It was found that more knowledge about the effects of ionizing radiation on the body and more awareness of the principles of radiation protection would help dentists to better observe the practical principles of radiation protection. Also, participating in radiation protection workshops could increase dentists' knowledge, and therefore, improve their performance.


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