scholarly journals Evaluation of the Effects of Age Group, Gender and Seasonal Factors on Vitamin D Levels in 9496 Children

2021 ◽  
Vol 4 (37) ◽  
pp. 365-370
Author(s):  
Zafer Bagci
Keyword(s):  
Vitamin D ◽  
Age Group ◽  
Seasonal Factors ◽  
Vitamin D Levels

scholarly journals Study of prevalence of osteoporosis in males of above 40 years age group attending SMS Hospital, Jaipur

2017 ◽  
Vol 3 (4) ◽  
pp. 837
Author(s):  
Parwez Qureshi ◽  
R. C. Meena ◽  
Jakir Husain ◽  
Gaurav Deshwar ◽  
Vineet Maheshwari ◽  
...  
Keyword(s):  
Vitamin D ◽  
Dietary Habits ◽  
Good Control ◽  
Age Group ◽  
Mineral Density ◽  
Cross Sectional ◽  
T Score ◽  
Vitamin D Levels ◽  
Study Population ◽  
Prevalence Of Osteoporosis

<p class="abstract"><strong>Background:</strong> Whenever osteoporosis is discussed, the focus is on women; men are far less likely to receive a diagnosis of osteoporosis or osteoporotic fracture because of considerable gaps in knowledge on male osteoporosis. The aim and objectives were to study the prevalence of osteoporosis in males of above 40 year age group attending SMS Hospital Jaipur &amp; to explore the influence of various modifiable and non-modifiable risk factors on BMD.</p><p class="abstract"><strong>Methods:</strong> Study Location: SMS Medical College and Hospital, Jaipur. Study design: Hospital based cross sectional study. Study period: April 2015 to December 2016. Sample Size: 200. Work up: After taking ethical clearance and informed verbal consent, demographic and clinical details were noted along with S- calcium, Vitamin D and bone mineral density assessment. Osteoporosis was defined as T score ≤−2.5 bone mass −1 to −2.5 and normal as &gt;−1. Data thus collected was analysed with help of SPSS 22.0 through frequency, percentages, Mean, SD and ANOVA.<strong></strong></p><p class="abstract"><strong>Results:</strong> Prevalence of osteopenia and osteoporosis in the study population was 28.5% and 11.5%. Age wise maximum prevalence was in the age group 71-80 years (31.81%). Prevalence of osteoporosis was more among Muslim community 20.83%, more in low socio economic group (BPL). T score of study population was -0.3705±1.41. The mean BMI, S-Calcium, Vitamin D levels and T score values among osteopenic and osteoporotic patients were statistically highly significant when compared to patients without osteo-penic/porotic changes (p&lt;0.05).</p><p><strong>Conclusions:</strong> Osteoporosis is a silent killer and prevention is better than cure as prevention requires simple steps such as good dietary habits, active life style, good control of systemic disorders, reduced intake of tobacco and alcohol.</p>

scholarly journals Association of vitamin D levels with simple febrile seizures in under five children: a case control study

2019 ◽  
Vol 6 (2) ◽  
pp. 365
Author(s):  
Virender Singh ◽  
Preeti Sharma ◽  
Deepika Dewan
Keyword(s):  
Vitamin D ◽  
Vitamin D Deficiency ◽  
Febrile Seizure ◽  
Case Control Study ◽  
Febrile Seizures ◽  
Case Control ◽  
First Episode ◽  
Age Group ◽  
Vitamin D Levels ◽  
Control Study

Background: There is increasing concern that vitamin D deficiency may play etiological role in Febrile seizures. Few studies have reported vitamin D deficiency in children with recurrent febrile seizures and hypocalcemia seizures.  The objective of this study is to explore vitamin D status in children aged 6 months to 5 years with first episode of febrile seizure and to find the association between vitamin D levels and febrile seizure.Methods: A hospital-based case control study was conducted in sub district hospital, Katra over a period of three years. Cases were children of age group 6 months to 5 years presenting with first episode of simple febrile seizure to the casualty or OPD. For each case, a control was selected with similar age group and same sex who came for short duration fever (<2 days) but without seizures. A 5ml of blood sample for measurement of 25 hydroxy vitamin D was taken from the peripheral vein of each participant by trained laboratory technician. In order to categorise various degrees of vitamin D deficiency, Indian Academy of paediatrics criteria was used. Results were presented in the form of percentages and Odds ratio was calculated as measure of association.Results: A total of 75 cases and 75 controls were included in the study. Cases and controls were comparable as per baseline characteristics. Strong and significant (p<0.01) association of febrile seizures with vit D levels was observed.Conclusions: There was a high prevalence of vitamin D insufficiency among cases of simple febrile seizure.

scholarly journals Indicators of vitamin D in case of Coronavirus infection COVID-19 in children

2021 ◽  
pp. 34-39
Author(s):  
A.G. Hasanov ◽  
◽  
I.E. Huseinova ◽  
Keyword(s):  
Vitamin D ◽  
Blood Serum ◽  
Age Groups ◽  
Serum Vitamin ◽  
Main Group ◽  
Control Group ◽  
Healthy Children ◽  
Age Group ◽  
Subgroup Ii ◽  
Vitamin D Levels

Purpose — to determine and compare vitamin D levels in children diagnosed with COVID-19-associated pneumonia and healthy children. Materials and methods. The study involved 90 children. The main group consisted of 75 inpatient children with a diagnosis of COVID-19-associated pneumonia (positive PCR — polymerase chain reaction with reverse transcription). Patients in the main group were divided into 2 subgroups: subgroup I consisted of 49 patients with a pneumonia of moderate course, and subgroup II — 26 patients with a pneumonia of severe course. The control group consisted of 15 practically healthy children. The scheme of examination of sick children included anamnestic data, the use of clinical, instrumental and laboratory, immunological examination methods. The concentration of vitamin D in the blood serum of sick and healthy children was determined by the method of enzyme3linked immunosorbent assay (ELISA). The indicators were measured on a Stat Fax 4700 device using a Pishqaman reactive kit (made in Germany). Results. The concentration of vitamin D in blood serum was 1.8 times lower in subgroup I and 2.0 times in subgroup II, compared with the control group. The average values of vitamin D in blood serum compared with the control group were <1.1 times lower in the age group <1 year, 1.1 times lower in the age group 1–3 years, and 2.3 times lower in the age group >3 years. Conclusions. Based on our research, it can be concluded that there is a relationship between vitamin D deficiency and COVID-19. Thus, the average level of vitamin D was lower in children with COVID-19-associated pneumonia, and varied depending on the severity of the disease (more pronounced changes were observed in severe pneumonia). There are also differences in vitamin D levels in the age groups of children with COVID-19-associated pneumonia: in children from age groups under 1 year and 1–3 years old the decrease in serum vitamin D level is less pronounced than in the age group over 3 years old. The main mechanisms of vitamin D involvement in the immune modulation process in COVID-19 require further study. The research was carried out in accordance with the principles of the Helsinki declaration. The study protocol was approved by the Local ethics committee of the participating institution. The informed consent of the patient was obtained for conducting the studies. No conflict of interest was declared by the authors. Key words: children, COVID-19, vitamin D.

scholarly journals Determination of Vitamin D Levels in Patients With Neurofibromatosis Type 1 in the Pediatric Age Group

2020 ◽  
Vol 13 ◽  
pp. 2632010X2092893
Author(s):  
Alessandra Santos ◽  
Mauro Geller ◽  
Spyros Mezitis ◽  
Allan E Rubenstein ◽  
Lisa Oliveira ◽  
...  
Keyword(s):  
Vitamin D ◽  
Children And Adolescents ◽  
Neurofibromatosis Type 1 ◽  
Sun Exposure ◽  
Neurofibromatosis Type ◽  
Age Group ◽  
Plexiform Neurofibromas ◽  
Vitamin D Levels ◽  
Cutaneous Neurofibromas

Introduction: Neurofibromatosis type 1 (NF1) is one of the most common autosomal dominant genetic disorders. Some clinical manifestations are present at birth, while some develop during childhood, and others can occur at any age. Given the early age at which patients develop clinical features, diagnosis is often made during childhood. The most prevalent features of NF1 are café au lait spots, dermal and plexiform neurofibromas, and learning disability. A variety of skeletal problems may be seen in NF1, including scoliosis, short stature, and pseudoarthrosis. Reduced skeletal bone mass has been documented to be a common phenomenon in children and adults with NF1. Decreased serum 25-hydroxyvitamin D (vitamin D) levels have been noted in adults and children with NF1 and have been reported to be inversely correlated with the number of dermal neurofibromas in adults. However, the actual correlation of vitamin D level to bone density and dermal neurofibroma number in children with NF1 remains unclear. Objectives: The primary objective of this study was to evaluate vitamin D levels among children and adolescents with NF1. The secondary objective was to describe the levels of vitamin D among children and adolescents with NF1, to verify in which age group there is a higher frequency of vitamin D alterations, and to explore vitamin D level correlations between age, gender, sun exposure, number of neurofibromas, and number of plexiform neurofibromas. Methods: This was an observational, cross-sectional, hospital-based study. We obtained a convenience sample of individuals with confirmed diagnosis of NF1 from patients attending the Medical Genetics Service of the IPPMG-UFRJ and Santa Casa de Misericórdia of Rio de Janeiro over a 24-month period. We evaluated vitamin D levels in blood samples of patients with NF1 by a chemiluminescent immunoassay method, and we correlated the results with gender, age, number of neurofibromas, number of plexiform neurofibromas, and satisfactory sun exposure. Results: Of the 55 patients, 28 (50.9%) were female and 27 (49.1%) were male. Patient ages ranged from a minimum of 1.2 to a maximum of 19.6 years (mean age 10.95 years) and the median was 11.11 years. Median and mean body mass index (BMI; z score) were -0.09 (minimum value -1.63 and maximum of 4.62) and 0.16, respectively. The mean value of vitamin D was 30.82 ng/mL (±12.31) and the median was 29 ng/mL (minimum value of 10.40 ng/mL and maximum of 79.19 ng/mL). Conclusions: The levels of vitamin D did not differ according to gender, age group, or the presence or number of cutaneous neurofibromas. Among patients with adequate sun exposure, there was a higher incidence of sufficient serum vitamin D levels. Patients with cutaneous neurofibromas in the 0 to 11 age group had a greater tendency to vitamin D sufficiency in relation to patients aged 11 to 19 years.

scholarly journals A study on vitamin D level among the patients attending in a private chamber in Dhaka city

2020 ◽  
Vol 10 (2) ◽  
pp. 393-396
Author(s):  
Moushumi Afrin Eva ◽  
Nasreen Begum ◽  
ASM Anawrul Kabir ◽  
Khondoker Wasee Ahmed ◽  
Mahbuba Sharmin ◽  
...  
Keyword(s):  
Vitamin D ◽  
Vitamin D Deficiency ◽  
Normal Level ◽  
Serum Vitamin ◽  
Age Group ◽  
Dhaka City ◽  
Observation Study ◽  
Vitamin D Levels ◽  
Diagnostic Center ◽  
The World

Background: Vitamin D deficiency is one of the most neglected public health issues all over the world. Near about 1 billion people round the world suffer from vitamin D deficiency. Most of the countries in Asia having high prevalence of vitamin D deficiency. Objective: To find the vitamin D level among the patients attending in a private chamber in Dhaka city Methodology: A cross sectional observation study was carried out in a renowned diagnostic center of Dhaka city from July 2017 to June 2018. A sample of 1523 adult patients aged 18 years and above, presented with generalized body aches and pains selected conveniently for the study. Blood samples were taken and serum vitamin D levels were measured. In this study, vitamin D concentration below10 ng/ml was considered as vitamin D deficiency, 20–30 ng/ml as insufficiency, and 30–100 ng/ml as vitamin D sufficient. Data were analyzed by using SPSS version 22. Result: Out of 1523 patients 69.5% were women and 30.5% men. Urban and rural distribution was 63.16% and 36.84% respectively. Among the participants vitamin D deficiency was 54%, 35.8% vitamin D insufficient, and only 9.8% had normal level of vitamin D, regarding age specific deficiency highest 71.8% was in 71-80 years age group. Out of 1058 female 39.5% were vitamin D deficient, 45.6% had insufficient vitamin D level. Only 14.9% female were found normal level. Age specific deficiency found highest 63.8% in 61-70 year age group. On the other hand out of 465 male participants, 24% were vitamin D deficient, 34% were insufficient and 42% had normal level vitamin D. Highest deficiency 42.5% found in age group 61-70years. Conclusion: Considering the study result deficiency was higher among female than male. In female vitamin D deficiency increased after age of 31year. Vitamin D deficiency found highest in old age and middle age group. Over all age specific deficiency found significantly highest in 71 – 80 years. In both male and female Vitamin D deficiency was found highest above 61years of age. Northern International Medical College Journal Vol.10 (2) Jan 2019: 393-396

scholarly journals A Clinical Study of Serum Vitamin D Levels in Chronic Tonsillitis among Paediatric Age Group

2020 ◽  
Vol 28 (1) ◽  
pp. 23-29
Author(s):  
Sudhakar Rao M.S. ◽  
Deepak Karade
Keyword(s):  
Vitamin D ◽  
Clinical Study ◽  
Active Form ◽  
Serum Vitamin ◽  
The Body ◽  
Chronic Tonsillitis ◽  
Age Group ◽  
Serum Vitamin D ◽  
Vitamin D Levels ◽  
Paediatric Age

Introduction Infectious diseases of the faucial tonsils are most frequently encountered by Oto-rhino-laryngologists. Vitamin D has got an important role in the production of surface Anti-microbial peptides (AMPs). Overall, the active form of vitamin D plays a vital role in maintaining the immune system of the body. This study aims to evaluate the association of vitamin D deficiency in chronic tonsillitis among paediatric age group. Materials and Methods It is a clinical study carried out in the Department of Oto-rhino-laryngology and Head and Neck surgery at a medical college in Ballari, Karnataka, India from January 2018 to January 2019 for the time period of 12 months. Patients were evaluated with the relevant investigations and digital X-ray nasopharynx along with serum Vitamin D level assessment. Results A total of 60 children with chronic tonsillitis were enrolled in this study. There were 26(43.3%) male children and 34(56.7%) females, ranging in age group from 5 to15 years, mean age is 9.82. The common clinical presentation was recurrent episodes of throat pain seen in all the patients (100%). On serum 25-hydroxyvitamin D assessment, 40(66.7%) patients were found to have deficiency and 20(33.3%) patients were having insufficiency. Mean is 17.99ng/ml and ranging from 9.13-28.58ng/ml.   Conclusion The study concludes that, the serum vitamin D levels in chronic tonsillitis among the paediatric age groups is found to be below normal levels and is unrelated to the socio demographic factors.

scholarly journals Exploring the link between Vitamin D and clinical outcomes in COVID-19.

2021 ◽  
Author(s):  
Prateek Lohia ◽  
Paul Nguyen ◽  
Neel Patel ◽  
Shweta Kapur
Keyword(s):  
Vitamin D ◽  
Mechanical Ventilation ◽  
Pulmonary Embolism ◽  
Cohort Study ◽  
Clinical Outcomes ◽  
Retrospective Cohort ◽  
Age Group ◽  
Icu Admission ◽  
Vitamin D Levels

Background The immunomodulating role of vitamin D might play a role in COVID-19 disease. Objective To study the association between vitamin D and clinical outcomes in COVID-19 patients. Methods Retrospective cohort study on COVID-19 patients with documented vitamin D levels within the last year. Vitamin D levels were grouped as ≥ 20 ng/mL or <20 ng/mL. Main outcomes were mortality, need for mechanical ventilation, new DVT or pulmonary embolism, and ICU admission. Results A total of 270 patients (mean (SD) age, 63.81 (14.69) years); 117 (43.3%) males; 216 (80%) African Americans; 139 (51.5%) in 65 and older age group were included. Vitamin D levels were less than 20 ng/ml in 95 (35.2%) patients. During admission, 72 patients (26.7%) died, 59 (21.9%) needed mechanical ventilation, and 87 (32.2%) required ICU. Vitamin D levels showed no significant association with mortality (OR=0.69; 95% CI, 0.39 - 1.24; p=0.21), need for mechanical ventilation (OR=1.23; 95% CI, 0.68 - 2.24; p=0.49), new DVT or PE(OR= 0.92; 95% CI, 0.16- 5.11; p=1.00) or ICU admission (OR=1.38; 95% CI, 0.81 - 2.34; p=0.23). Conclusion We did not find any significant association of vitamin D levels with mortality, the need for mechanical ventilation, ICU admission and the development of thromboembolism in COVID-19 patients.

Abstract #421 Association of Vitamin D Levels with the Severity of Fibrosis in NAFLD Patients with Type 2 Diabetes

2019 ◽  
Vol 25 ◽  
pp. 199-200
Author(s):  
Prathyusha Chitrapu ◽  
Shilpa Jain ◽  
Aaron Thrift ◽  
Maya Balakrishnan ◽  
Ruchi Gaba
Keyword(s):  
Type 2 Diabetes ◽  
Vitamin D ◽  
Vitamin D Levels
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