scholarly journals Pattern of lipid fractions in plasma and cardiovascular tissues under Cryptorchidism in albino rat

2010 ◽  
Vol 2 (1) ◽  
pp. 1-4
Author(s):  
K. Narasimha Varma ◽  
E. Madhuri ◽  
M. Bhaskar
Keyword(s):  
Fatty Acids ◽  
Dorsal Aorta ◽  
Albino Rats ◽  
Significant Elevation ◽  
Albino Rat ◽  
Cardiovascular Tissues ◽  
Wistar Strain ◽  
Bilateral Cryptorchidism ◽  
Lipid Fractions ◽  
Cardio Vascular

Bilateral cryptorchidism was induced surgically in adult wistar strain male albino rats and lipid fractions such as total lipids, total cholesterol, Free cholesterol, Esterified cholesterol, phospholipids, Triglycerides and free fatty acids were analysed in the plasma, heart and dorsal aorta. The lipid fractions such as triglycerides (56.63%), free (20.82%) and esterified (61.25%) cholesterol as well as fatty acids in glycerol (64.42%) had significant elevation in the plasma of cryptorchid animals. Similarly LDL lipid fractions (64.99%) were also elevated markedly undercryptorchid conditions which are the markers of the obesity and atherosclerosis. The lipid fractions such as triglycerides (50.47%, 48.17%), cholesterol (74.64%, 67.7%) and phospholipids (42.04%, 68.88%) showed significant elevations in the heart and dorsal aorta of the cryptorchid animals over the control. The heart, dorsal aorta and plasma had significant accumulation of triglycerides and cholesterol fractions, suggesting the possible deposition of lipid fractions in the tissues, which can be attributed to the possible suppression in the mobilization of lipid fractions into energy metabolism. Such an accumulation of lipid fractions under cryptorchid condition can be considered as the development of risk factor for the cardio-vascular disorders.

THE LIPID COMPOSITION AND WATER CONTENT OF BRAIN, HEART, LUNG, LIVER, GUT, AND SKIN IN THE HOST COMPONENT OF THE ALBINO RAT–WALKER CARCINOMA 256 DUAL ORGANISM

1953 ◽  
Vol 31 (6) ◽  
pp. 493-504
Author(s):  
Eldon M. Boyd ◽  
H. D. McEwen ◽  
M. N. Shanas
Keyword(s):  
Fatty Acids ◽  
Total Lipid ◽  
Free Cholesterol ◽  
Water Levels ◽  
Albino Rats ◽  
P Value ◽  
Albino Rat ◽  
Water Shift ◽  
Total Fatty Acids ◽  
Walker Carcinoma

The carcass of albino rats bearing Walker carcinoma 256 contains, at or near death of the dual organism, concentrations of lipids and water altered in the direction of the concentrations of these constituents in the tumor component. The objective of the investigation herein reported was to find the extent to which brain, heart, lung, liver, gut, and skin participated in this shift of lipid and water levels of the host carcass. Total lipid, neutral fat, total fatty acids, total cholesterol, ester cholesterol, free cholesterol, and phospholipid of these tissues were measured by oxidative micromethods in 23 albino rats bearing Walker carcinoma 256 at or near death of the dual organism. The results were expressed as gm. per 100 gm. dry weight of tissue and compared with corresponding values in 23 littermate albino rats without tumors, and differences with a P value of 0.01 or less were noted. Brain could be proved to take no part in the lipid and water shift in the carcass. Heart, lung, liver, and gut participated in the increased water shift. Liver participated in the increased free cholesterol shift. Skin and gut participated markedly in the decreased total lipid, neutral fat, and total fatty acids shift. Gut participated in the increased phospholipid shift. There were no other significant changes in lipid or water levels. These data are further evidence of the metabolism-directing influence of Walker carcinoma 256 on the host.

scholarly journals Biochemical Changes in Fatty Acids, Hydrocarbons and Sterols as well as Total Lipids of Albino Rats Ingested some Synthetic Colourants and Flavourants as Food Additives

2017 ◽  
Vol 9 (1) ◽  
pp. 40-47
Author(s):  
Hossam S. EL-BELTAGI ◽  
Emam A. ABDEL-RAHIM
Keyword(s):  
Fatty Acids ◽  
Unsaturated Fatty Acids ◽  
Saturated Fatty Acids ◽  
Food Additives ◽  
Biochemical Changes ◽  
The Other ◽  
Albino Rats ◽  
Total Lipids ◽  
Form Complex ◽  
Lipid Fractions

The present study was carried out to investigate the effect of ingested synthetic food colourants or flavourants on total lipids content feces. The feces of rats ingested synthetic food colourants or flavourants has more lipids than that of control feces. In treated rat feces some fatty acids were disappeared (C19) or appeared (C14) while the other were increased (C15, C20, C18:2) or decreased (C6) when compared with the control feces. Most of unsaturated fatty acids (un SFA) might bind with the synthetic food colourants or flavourants and secreted in feces, but less consumed than saturated fatty acids (SFA) which, observed on hydrocarbon components, but sterols including cholesterol were more secreted by synthetic food additives treatments. Generally, the increase of total lipids and lipid fractions in feces such as unsaturated fatty acids (un SFA), total sterols (TS) especially cholesterol maybe due to their abilities to bind with food additives and form complex which secreted in feces.

scholarly journals Alterations in carbohydrate metabolism under cryptorchid condition in albino rats

2009 ◽  
Vol 1 (1) ◽  
pp. 62-65
Author(s):  
K. Narasimha Varma ◽  
E. Madhuri ◽  
S. Sadak Basha ◽  
YR. Radha Madhavi ◽  
M Guru Sekhar ◽  
...  
Keyword(s):  
Lactic Acid ◽  
Prostate Gland ◽  
The Body ◽  
Albino Rats ◽  
Phosphorylase Activity ◽  
Glucose Content ◽  
Reproductive Tissues ◽  
Wistar Strain ◽  
Bilateral Cryptorchidism ◽  
Free Glucose

Bilateral cryptorchidism was induced surgically in adult wistar strain albino rats and the carbohydrate metabolic pathway has been studied in testis, and sex accessory organs of both control and cryptorchid animals by estimating the marker enzymes and the substrates of the metabolism. In cryptorchid animal tissues, accumulation of lactic acid and glycogen was observed with inhibited phosphorylase activity in comparison to the controls. The reproductive tissues like testis, epididymis, prostate gland and seminal vesicles had shown remarkable elevation in the glycogen content, which can be attributed to decreased phosphorylase activity. In view of androgen dependent nature of phosphorylase its inhibition can be correlated to decreased testosterone circulation in the body. Consequently the free glucose content of the tissues was markedly decreased suggesting a decrease in the mobilization of the carbohydrates into energy metabolism. All the reproductive tissues had shown significant accumulation of lactic acid with inhibited oxidative enzyme activities. Thus the reproductive tissue oxidative metabolism had been suppressed during cryptorchidism leading to a shift towards glycolysis and creating a situation of functional suppression.

Effects of Dihydroquercetin on Behavior of Albino Rat Offspring with Transgenerational Chemical Body Burden

2020 ◽  
pp. 38-41
Author(s):  
E.A. Kapustina ◽  
L.G. Lisetskaya
Keyword(s):  
Physical Activity ◽  
Open Field ◽  
Antioxidant Properties ◽  
Body Burden ◽  
Statistical Processing ◽  
Lead Toxicity ◽  
Absorption Spectrometry ◽  
Albino Rats ◽  
Albino Rat ◽  
Rat Offspring

Introduction. Lead pollution is a common environmental problem. Having no physiological functions, this toxicant has a negative polytropic impact on a body, including neurotoxic, reproductive, and transgenerational effects. The mechanism of lead toxicity is oxidative stress. Flavonoids have active antioxidant properties. They are widely represented in plant foods, are able to restore protective capabilities of cells and have chelating properties with respect to lead. One of the representatives of this group of substances is dihydroquercetin. The objective was to study the effect of dihydroquercetin on behavior of rats with hereditary chemical body burden exposed to lead at 60 mg/kg during 25 days. Materials and methods. We studied the behavior of rat offspring in an open field and established their blood lead levels by electrothermal atomization atomic absorption spectrometry. For statistical processing the U-Mann – Whitney test was used. Results. In the present experiment, the effect of lead on the offspring of male albino rats exposed to 60 mg/kg of lead for 25 days caused changes in the activity of animals in the open field. The severity of changes was more pronounced in animals with a hereditary chemical body burden. These animals showed a decrease in orientation and physical activity and increased anxiety. In rats with a hereditary burden, changes in behavior were detected when administering dihydroquercetin. The activity of animals demonstrated a positive dynamics: we observed a statistically significant increase in physical activity and orientation. The number and duration of behavioral acts approached control values. Conclusions. The revealed effects of lead on the offspring of albino rats with a transgenerational chemical body burden require further study to understand the mechanism of the phenomenon.

Effect of Propolis-Supplemented Diet on Body Composition and Endocrine Function of Adipose Tissue

2020 ◽  
Vol 19 (2) ◽  
pp. 217-221
Author(s):  
Maria Jesús Lisbona-González ◽  
Candela Reyes-Botella ◽  
Esther Muñoz-Soto ◽  
Maria Victoria Olmedo-Gaya, ◽  
Jorge Moreno-Fernandez ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Body Composition ◽  
Adipose Tissue ◽  
Endocrine Function ◽  
Control Group ◽  
Albino Rats ◽  
Standard Diet ◽  
Reduced Body ◽  
Esterified Fatty Acids ◽  
Wistar Albino Rats

Adipose tissue is an endocrine organ and has central role in interaction with other organs or tissues while propolis can induce lipolysis. Therefore, the aim of this study is to provide detailed information about adipose tissue homeostasis modifications and body composition during propolis supplement consumption. Twenty male Wistar albino rats (8 weeks) were divided into two groups of 10 animals each and fed for 90 days with two different types of diets: standard for the control group (diet C) and standard diet + 2% propolis (diet P). Thyroid hormones did not show differences, while ghrelin and adiponectin decreased in the group that was fed propolis. Insulin, leptin, and non-esterified fatty acids also increased along with reduced body weight and fat, in addition to increased lean mass when propolis was in the diet. We conclude that propolis could decrease ghrelin and adiponectin but increase non-esterified fatty acids and insulin secretion, which improves body composition.

scholarly journals Effects of peroral alanine administration in lactating ewes with decreased availability of glucose

1997 ◽  
Vol 78 (5) ◽  
pp. 805-813 ◽  
Author(s):  
Kjell Holtenius ◽  
Paul Holtenius
Keyword(s):  
Fatty Acids ◽  
Plasma Level ◽  
Free Fatty Acids ◽  
Skeletal Muscles ◽  
Plasma Insulin ◽  
Glucose Oxidation ◽  
Negative Energy ◽  
Crossover Design ◽  
Metabolic Effects ◽  
Significant Elevation

The metabolic effects of a phlorizin-induced drainage of glucose were studied in six lactating ewes with or without peroral alanine drenches in a study of crossover design. Phlorizin gave rise to a small, but significant, elevation of plasma β-hydroxybutyrate. The plasma level of alanine decreased by about 30 % due to the phlorizin injections and alanine was negatively correlated to β-hydroxybutyrate. The plasma level of free fatty acids increased due to phlorizin. Plasma insulin and glucose concentrations were not significantly affected by phlorizin while glucagon level showed a small but significant increase. Peroral alanine drenches to phlorizin-treated ewes gave rise to a transitory elevation of alanine in plasma. The plasma level of free fatty acids was about 40 % lower in phlorizin-treated ewes receiving alanine and β-hydroxybutyrate tended to be lower (P < 0.08). We suggest that β-hydroxybutyrate, apart from its function as an oxidative fuel, might play an important role by limiting glucose oxidation and protein degradation in skeletal muscles during periods of negative energy balance in ruminants. Furthermore, it is suggested that alanine supplementation decreases lipolysis and ketogenesis in lactating ewes.

Effect of induced bilateral cryptorchidism on the carbohydrate metabolism of reproductive tissues in albino rats

1983 ◽  
Vol 91 (5) ◽  
pp. 405-410 ◽  
Author(s):  
K. Venkatarami Reddy ◽  
N. Geethanjali ◽  
Y. Dhananjaya Reddy ◽  
P. Reddanna ◽  
S. Govindappa
Keyword(s):  
Carbohydrate Metabolism ◽  
Albino Rats ◽  
Reproductive Tissues ◽  
Bilateral Cryptorchidism

Effect of Morphine Sulfate on Spontaneous Activity Level of the Albino Rat

1965 ◽  
Vol 16 (3) ◽  
pp. 693-696 ◽  
Author(s):  
L. Glenn Collins
Keyword(s):  
Drug Effect ◽  
Activity Wheel ◽  
Activity Level ◽  
Morphine Sulfate ◽  
Albino Rats ◽  
Systematic Effect ◽  
General Activity ◽  
Albino Rat ◽  
General Activity Level ◽  
Hunger Drive

In two experiments involving 40 albino rats and two dosage levels of morphine sulfate it was found that relatively high analgesic dosages of morphine significantly depressed general activity level in the revolving drum. Also, there was a significant interaction between drug effect and hunger drive. In the case of moderate analgesic doses (7 mg/kg) no systematic effect of morphine on activity-wheel performance was noted.

scholarly journals CHRONIC SODIUM CHLORIDE TOXICITY IN THE ALBINO RAT

1953 ◽  
Vol 98 (1) ◽  
pp. 71-80 ◽  
Author(s):  
George R. Meneely ◽  
Robert G. Tucker ◽  
William J. Darby ◽  
Stewart H. Auerbach
Keyword(s):  
Blood Pressure ◽  
Sodium Chloride ◽  
Relative Volume ◽  
Dietary Sodium ◽  
Albino Rats ◽  
Albino Rat ◽  
Positive Linear Correlation ◽  
Ad Libitum ◽  
Histologic Changes ◽  
Dietary Sodium Chloride

Sustained arterial hypertension developed in male, albino rats chronically fed diets rich in sodium chloride with demineralized drinking water available ad libitum. After 12 months of the experimental regimen a positive, linear correlation (r = 0.91) was found between the systolic blood pressure and the concentration of sodium chloride in the diet. A syndrome of edema and renal failure was observed in 18 per cent of the group fed at the level of 7.0 to 9.8 per cent of sodium chloride. Significant histologic changes occurred in the kidneys and certain other organs in rats consuming rations containing these levels of NaCl. The relative volume of the radiosodium space was increased in the rat by high dietary sodium chloride.

Visual thresholds in albino and pigmented rats

1992 ◽  
Vol 9 (3-4) ◽  
pp. 409-414 ◽  
Author(s):  
Pilar Herreros De Tejada ◽  
Daniel G. Green ◽  
Carmen Muñoz Tedó
Keyword(s):  
Evoked Potentials ◽  
Superior Colliculus ◽  
Absolute Threshold ◽  
Albino Rats ◽  
Response Curves ◽  
Albino Rat ◽  
A Value ◽  
Visual Evoked Cortical Potential ◽  
Single Unit Recordings ◽  
Visual Evoked

AbstractAlbino rats have recently been reported to have increment thresholds against dim backgrounds that are two log units higher than those of pigmented rats. We, on the other hand, have failed to confirm these differences using electroretinogram b waves and pupillary light reflexes. This paper reports on experiments using evoked potentials from cortex and colliculus and single-unit recordings from colliculus.We recorded visual-evoked potentials from cortex and superior colliculus in the strains of albino (CD) and pigmented (Long-Evans) rats used in the earlier studies. Thresholds were determined on eight fully dark-adapted animals by extrapolating intensity-response curves to the point at which there was zero evoked potential. The average dark-adapted threshold for the visual-evoked cortical potential was —5.26 log cd/m2in pigmented and —5.80 log cd/m2 in albino animals. The average dark-adapted threshold for the superior colliculus evoked response was —5.54 log cd/m2 in pigmented and —5.84 log cd/m2 in albinos. The differences were not statistically significant. On the same apparatus, the average absolute threshold for three human observers was —5.3 log cd/m2, a value close to the rat dark-adapted thresholds. Thus, visual-evoked cortical potentials and superior collicular evoked potentials failed to confirm the report of higher dark-adapted thresholds for albinos. In addition, we find that single units in superior colliculus in the albino rat respond to very dim flashes.

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