The risk of developing cardiovascular complications in employees who operate and maintain communication facilities based on wired and wireless technologies

2021 ◽  
Vol 61 (4) ◽  
pp. 212-217
Author(s):  
Lyudmila P. Kuzmina ◽  
Maria M. Kolyaskina ◽  
Lyudmila M. Bezrukavnikova ◽  
Nana A. Anvarul ◽  
Anastasia V. Karpushina
Keyword(s):  
Cardiovascular Risk ◽  
Lipid Metabolism ◽  
Rating Scale ◽  
Cardiovascular Complications ◽  
Middle Aged ◽  
Wireless Technologies ◽  
Biological Stress ◽  
Increased Risk ◽  
Atherogenicity Index ◽  
Vascular Age

Introduction. Heart disease has remained the leading cause of death in the world for the past 20 years. The development and progression of cardiovascular diseases, along with genetic, somatic, behavioral, socioeconomic, environmental, and other risk factors, are significantly affected by unfavorable industrial and professional aspects: physical-vibration, noise, temperature disturbance; ergonomic - inactivity, and monotonous work, physical overstrain, chemical, biological, stress, etc. The primary pathogenetic mechanism leading to the development of CHD and fatal complications - myocardial infarction, strokes, thrombosis, and other diseases of the cardiovascular system is atherosclerosis. The study aimed to assess the risk of developing cardiovascular complications in employees who operate and maintain communication facilities based on wired and wireless technologies Materials and methods. An in-depth examination of the health status of 50 employees of the service for the operation of radio equipment and communications was conducted. Blood serum levels of glucose, cholesterol, triglycerides, HDL, and LDL were determined, and the atherogenicity index was calculated. The probability of total risk of cardiovascular complications and five-year cardiovascular risk was calculated for all the examined patients according to the European SCORE scale and the ASCORE rating scale. The "Vascular age" was also calculated. Results. Based on the analysis of lipid metabolism indicators, a high cardiovascular risk was identified in 40% of the examined patients. Increased values of the atherogenicity index were already observed in middle-aged people (45-60 years). Analysis of the data obtained using the SCORE and ASCORE assessment scales revealed a high risk of developing cardiovascular complications in middle-aged (45-60 years) and elderly (61-74 years) individuals. The excess of the vascular age in comparison with the real (passport) age was established in middle-aged (45-60 years) and elderly (61-74 years) individuals, on average, 7 (p<0.001) and 5 (p=0.026) years, respectively. Conclusion. The most pronounced changes in lipid metabolism and the risk of cardiovascular risk were in people of the most working age (45-60). In this regard, it is necessary to develop preventive measures aimed at cardioscreening to detect early signs of health disorders, prevent the development of cardiovascular complications, and the formation of groups at increased risk of diseases.

scholarly journals Cardiovascular complications according to severity of renal artery stenosis based on Doppler ultrasound

2021 ◽  
Author(s):  
Łukasz Artyszuk ◽  
Bartosz Symonides ◽  
Zbigniew Gaciong ◽  
Cezary Szmigielski
Keyword(s):  
Cardiovascular Risk ◽  
Renal Artery ◽  
Renal Artery Stenosis ◽  
Doppler Ultrasound ◽  
Cardiovascular Events ◽  
Cardiovascular Complications ◽  
Artery Stenosis ◽  
Control Group ◽  
Percutaneous Coronary Angioplasty ◽  
Increased Risk

IntroductionThe interactions between atherosclerotic renal artery stenosis, independently of severity, and cardiovascular risk, and mortality, are complex and have not been fully researched. The aim of this study was the assessment of the risk of cardiovascular events and mortality in patients with haemodynamically non-significant (NS-RAS) and significant renal artery stenosis (S-RAS) diagnosed with ultrasonography.Material and methodsThe study group consisted of all consecutive patients (n = 2059) who underwent Doppler ultrasound of the renal arteries during a 4-year period. The patients were divided, according to the renal aortic ratio (RAR), into the following groups: S-RAS (RAR ≥ 3.5), NS-RAS (1 < RAR < 3.5), and normal RAR (control group; RAR ≤ 1). The risk of cardiovascular events and death was estimated using Cox’s proportional hazard model, including severity of RAS, age, and gender, based on the data from the National Health Fund on causes of hospitalization, deaths, and statistics on percutaneous coronary angioplasty procedures.ResultsSignificant renal artery stenosis was found in 112 patients (5.4%), NS-RAS in 313 patients (15.2%), and 1634 patients (79.4%) were qualified to the control group. The NS-RAS group had an increased risk of stroke (7.0% vs. 3.0%, HR = 1.77, p = 0.032); S-RAS patients were at increased risk of heart failure (16.1% vs. 5.2%, HR = 2.19, p = 0.002) and death (19.6% vs. 4.3%, HR = 3.08, p < 0.001).ConclusionsThe presence of haemodynamically non-significant renal artery stenosis is an indicator of systemic atherosclerotic changes in vital organs and an important cardiovascular risk factor for stroke.

scholarly journals Risk factors of cerebral microbleeds in young and middle-aged patients with hypertension

2021 ◽  
Vol 26 (4) ◽  
pp. 685-691
Author(s):  
Pingping He ◽  
Rui Jiang ◽  
Jianhao Li ◽  
Peng Wang ◽  
Feizhou Du
Keyword(s):  
Risk Factors ◽  
Lipid Metabolism ◽  
Brain Tissue ◽  
Rating Scale ◽  
Cerebral Microbleeds ◽  
Smoking History ◽  
Middle Aged ◽  
Aged Patients ◽  
Abnormal Lipid Metabolism ◽  
Deep Brain

Background & Objectives: This study aimed to explore the incidence and potential risk factors of cerebral microbleeds (CMBs) in young and middle-aged patients with hypertension. Methods: We retrospectively analyzed the clinical data of young and middle-aged patients with hypertension in the Department of Neurology, General Hospital of Western Theater Command, Chengdu, China between August 2018 and December 2020. The demographic baseline, laboratory parameters and clinical imaging data were collected. Microbleed anatomical rating scale (MARS) was applied to evaluate the presence, amount, and topographical distributions of CMBs. Results: Among 196 young and middle-aged patients with hypertension, 84 (42.9%) patients had CMBs. CMBs were more likely to occur in the deep brain tissue regions (41.8%), followed by lobar or infratentorial region. White matter hyperintensity (OR, 5.262; 95%CI, 1.314-21.075; P=0.019), abnormal lipid metabolism (OR, 3.832; 95%CI, 1.578-9.306; P=0.003), usage of anti-platelet aggregation drugs (OR, 2.947; 95%CI, 1.138-7.632; P=0.026), smoking history (OR, 3.218; 95%CI, 1.073-9.651; P=0.037), and hyperhomocysteinemia (OR, 1.415; 95%CI, 1.018-1.967; P=0.039) were independently associated with deep or infratentorial CMBs in young and middle-aged patients with hypertension. However, the occurrence of strictly lobar CMBs was only independently associated with abnormal lipid metabolism (OR, 4.162; 95%CI, 1.685-10.282; P=0.002). Conclusions: The rate of CMBs was high in young and middle-aged patients with hypertension, most commonly occurring in the deep brain tissue region. While multiple risk factors were identified to be associated with deep or infratentorial CMBs, the occurrence of strictly lobar CMBs was only associated with abnormal lipid metabolism.

scholarly journals Underlying cardiovascular risk and major adverse cardiovascular events after acute respiratory infection: a population-based cohort study of over 4.2 million individuals in England, 2008-2018

2021 ◽  
Author(s):  
Jennifer Davidson ◽  
Amitava Banerjee ◽  
Liam Smeeth ◽  
Helen I McDonald ◽  
Daniel J Grint ◽  
...  
Keyword(s):  
Cohort Study ◽  
Cardiovascular Risk ◽  
Cardiovascular Events ◽  
Respiratory Infections ◽  
Cardiovascular Complications ◽  
Major Adverse Cardiovascular Events ◽  
Mortality Data ◽  
Clinical Practice Research Datalink ◽  
Increased Risk ◽  
One Year

Background While acute respiratory infections (ARIs) can lead to cardiovascular complications, the effect of underlying cardiovascular risk profile on ARI incidence and cardiovascular complications in those without established cardiovascular disease (CVD) is unknown. Whether to consider individuals at raised cardiovascular risk a priority group for vaccination against respiratory infections therefore remains unclear. Methods We conducted a cohort study in individuals aged 40-64 years without established CVD or a chronic health condition eligible for influenza vaccination, using Clinical Practice Research Datalink GOLD and Aurum data from 01/09/2008-31/08/2018 linked to Hospital Episode Statistics Admitted Patient Care and Office for National Statistics mortality data from England. We classified cardiovascular risk based on diagnosed hypertension and overall predicted cardiovascular risk estimated using QRISK2 score (≥10% compared with <10%). Using multivariable Poisson regression models, we obtained incidence rate ratios (IRR) for ARI. Among individuals who had an ARI, we then used multivariable Cox regression to obtain hazard ratios (HR) for the risk of major adverse cardiovascular events (MACE) within one year of infection. Findings 4,212,930 individuals were included; 12.5% had hypertension and 14.4% had a QRISK2 score ≥10%. After adjusting for confounders, patients with hypertension (IRR 1.04, 95% CI 1.03-1.05) or QRISK2 score ≥10% (IRR 1.39, 1.37-1.40) had a higher incidence of ARI. Of the 442,408 individuals with an ARI, 4,196 had a MACE within one year of infection. After adjustment, hypertension (HR 1.98, 1.83-2.15) and QRISK2 score ≥10% (HR 3.65, 3.42-3.89) were associated with substantial increased risk of a MACE after infection. Interpretation People without diagnosed CVD but who have raised cardiovascular risk, measured by diagnosed hypertension or, in particular, overall predicted cardiovascular risk, have increased incidence of both ARI and cardiovascular complications following an ARI.

scholarly journals Lipid Metabolism and Cardiovascular Risk in HIV-1 Infection and HAART: Present and Future Problems

Cholesterol ◽  
2010 ◽  
Vol 2010 ◽  
pp. 1-13 ◽  
Author(s):  
Sara Melzi ◽  
Laura Carenzi ◽  
Maria Vittoria Cossu ◽  
Simone Passerini ◽  
Amedeo Capetti ◽  
...  
Keyword(s):  
Cardiovascular Risk ◽  
Lipid Metabolism ◽  
Antiretroviral Therapy ◽  
Hiv Therapy ◽  
Increased Risk ◽  
Negative Effect ◽  
Hiv Drugs ◽  
Lipid Abnormalities ◽  
The Impact ◽  
Hiv 1

Many infections favor or are directly implicated with lipid metabolism perturbations and/or increased risk of coronary heart disease (CHD). HIV itself has been shown to increase lipogenesis in the liver and to alter the lipid profile, while the presence of unsafe habits, addiction, comorbidities, and AIDS-related diseases increases substantially the risk of cardiovascular disease (CVD) in the HIV-infected population. Antiretroviral therapy reduces such stimuli but many drugs have intrinsic toxicity profiles impacting on metabolism or potential direct cardiotoxicity. In a moment when the main guidelines of HIV therapy are predating the point when to start treating, we mean to highlight the contribution of HIV-1 to lipid alteration and inflammation, the impact of antiretroviral therapy, the decisions on what drugs to use to reduce the probability of having a cardiovascular event, the increasing use of statins and fibrates in HIV-1 infected subjects, and finally the switch strategies, that balance effectiveness and toxicity to move the decision to change HIV drugs. Early treatment might reduce the negative effect of HIV on overall cardiovascular risk but may also evidence the impact of drugs, and the final balance (reduction or increase in CHD and lipid abnormalities) is not known up to date.

scholarly journals Role of Adipokines in Atherosclerosis: Interferences with Cardiovascular Complications in Rheumatic Diseases

2012 ◽  
Vol 2012 ◽  
pp. 1-14 ◽  
Author(s):  
Morena Scotece ◽  
Javier Conde ◽  
Rodolfo Gómez ◽  
Verónica López ◽  
Jesús Pino ◽  
...  
Keyword(s):  
Cardiovascular Risk ◽  
Cardiovascular Diseases ◽  
Rheumatic Diseases ◽  
Lupus Erythematosus ◽  
Cardiovascular Complications ◽  
Risk Of Mortality ◽  
Increased Risk ◽  
Pathologic Alteration ◽  
Holistic Vision

Patients with rheumatic diseases have an increased risk of mortality by cardiovascular events. In fact, several rheumatic diseases such as rheumatoid arthritis, osteoarthritis, systemic lupus erythematosus, and ankylosing spondylitis are associated with a higher prevalence of cardiovascular diseases (CVDs). Although traditional cardiovascular risk factors have been involved in the pathogenesis of cardiovascular diseases in rheumatic patients, these alterations do not completely explain the enhanced cardiovascular risk in this population. Obesity and its pathologic alteration of fat mass and dysfunction, due to an altered pattern of secretion of proinflammatory adipokines, could be one of the links between cardiovascular and rheumatic diseases. Indeed, the incidence of CVDs is augmented in obese individuals with rheumatic disorders. Thus, in this paper we explore in detail the relationships among adipokines, rheumatic diseases, and cardiovascular complications by giving to the reader a holistic vision and several suggestions for future perspectives and potential clinical implications.

scholarly journals Risk factors of disturbances in carbohydrate and lipid metabolism and some pleiotropic effects of antihypertensive therapy in pregnant women

2013 ◽  
Vol 10 (1) ◽  
pp. 9-13
Author(s):  
A V Padyganova
Keyword(s):  
Risk Factors ◽  
Cardiovascular Risk ◽  
Lipid Metabolism ◽  
Arterial Hypertension ◽  
Cardiovascular Complications ◽  
Mechanisms Of Action ◽  
High Cardiovascular Risk ◽  
Carbohydrate And Lipid Metabolism ◽  
Exchange Processes ◽  
Modern Population

The any kind of hypertension developing during the pregnancy, associated with high cardiovascular risk in the future. At the pregnancy complicated by development by arterial hypertension, there are more expressed changes of a carbohydrate and lipide metabolism, than it is peculiar to normally proceeding pregnancy, were by important pathogenetic links of obesity, diabetes, cardiovascular complications. Identification of new mechanisms of action of antihypertensive means associated with positive influences on exchange processes, is represented very demanded, considering pandemic nature of prevalence of metabolic violations in modern population.

scholarly journals Complement Activation on Endothelial Cell-Derived Microparticles—A Key Determinant for Cardiovascular Risk in Patients with Systemic Lupus Erythematosus?

Medicina ◽  
2020 ◽  
Vol 56 (10) ◽  
pp. 533
Author(s):  
Naomi Martin ◽  
Xiaodie Tu ◽  
Alicia J. Egan ◽  
Cordula Stover
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Cardiovascular Risk ◽  
Lupus Erythematosus ◽  
Cardiovascular Complications ◽  
Chronic Inflammatory Disease ◽  
Systemic Autoimmune Disease ◽  
Systemic Lupus ◽  
Additional Risk ◽  
Increased Risk ◽  
Circulating Microparticles

Systemic lupus erythematosus is a classical systemic autoimmune disease that overactivates complement and can affect all organs. Early diagnosis and effective management are important in this immune-complex-mediated chronic inflammatory disease, which has a strong component of vasculitis and carries an increased risk of thrombosis, even in the absence of antiphospholipid antibodies. Development of lupus nephritis can be life limiting but is managed with dialysis and renal transplantation. Therefore, data have become available that cardiovascular risk poses a serious feature of systemic lupus erythematosus that requires monitoring and prospective treatment. Cell-derived microparticles circulate in plasma and thereby intersect the humoral and cellular component of inflammation. They are involved in disease pathophysiology, particularly thrombosis, and represent a known cardiovascular risk. This viewpoint argues that a focus on characteristics of circulating microparticles measured in patients with systemic lupus erythematosus may help to classify certain ethnic groups who are especially at additional risk of experiencing cardiovascular complications.

scholarly journals Women with cardiovascular risk after preeclampsia: is there follow-up within the Unified Health System in Brazil?

2014 ◽  
Vol 22 (1) ◽  
pp. 93-99 ◽  
Author(s):  
Maria de Lourdes Costa da Silva ◽  
Ana Cristina Araújo de Andrade Galvão ◽  
Nilba Lima de Souza ◽  
George Dantas de Azevedo ◽  
Selma Maria Bezerra Jerônimo ◽  
...  
Keyword(s):  
Cardiovascular Risk ◽  
Health System ◽  
Statistical Significance ◽  
Cardiovascular Complications ◽  
Unified Health System ◽  
Increased Risk ◽  
History Of ◽  
Index Weight ◽  
The City

OBJECTIVES: to identify women with cardiovascular risk, five years after a preeclampsic episode (PE), and identify the follow-up of these women within the Unified Health System (Sistema Único de Saúde - SUS), in the city of Natal/RN. METHODS: a quantitative and exploratory study conducted at the Januário Cicco University Maternity Ward/RN. The sample consisted of 130 women, 65 with a PE episode and 65 who were normotensive. RESULTS: we found statistical significance with regard to body mass index, weight, family history of cardiovascular disease (CVD) and cardiovascular complications when comparing women with previous PE to normotensive women. The groups were unaware of their cardiovascular risk factors and, in addition, they reported difficulties in accessing primary health care (PHC) services. CONCLUSIONS: women with a PE history are at increased risk of developing CVD, unaware of late PE complications, and lacked customized care when compared to normotensive patients.

scholarly journals Long-term cardiovascular complications following sepsis: is senescence the missing link?

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Hamid Merdji ◽  
Valérie Schini-Kerth ◽  
Ferhat Meziani ◽  
Florence Toti
Keyword(s):  
Cardiovascular Risk ◽  
Cardiovascular Events ◽  
Cardiovascular Complications ◽  
Sepsis Syndrome ◽  
Major Adverse Cardiovascular Events ◽  
Accelerated Ageing ◽  
Premature Senescence ◽  
Increased Risk ◽  
Vascular Senescence

AbstractAmong the long-term consequences of sepsis (also termed “post-sepsis syndrome”) the increased risk of unexplained cardiovascular complications, such as myocardial infarction, acute heart failure or stroke, is one of the emerging specific health concerns. The vascular accelerated ageing also named premature senescence is a potential mechanism contributing to atherothrombosis, consequently leading to cardiovascular events. Indeed, vascular senescence-associated major adverse cardiovascular events (MACE) are a potential feature in sepsis survivors and of the elderly at cardiovascular risk. In these patients, accelerated vascular senescence could be one of the potential facilitating mechanisms. This review will focus on premature senescence in sepsis regardless of age. It will highlight and refine the potential relationships between sepsis and accelerated vascular senescence. In particular, key cellular mechanisms contributing to cardiovascular events in post-sepsis syndrome will be highlighted, and potential therapeutic strategies to reduce the cardiovascular risk will be further discussed.

scholarly journals Evaluation of cardiovascular risk factors in women with left breast cancer of middle-aged and elderly age at the stage of chemotherapy and radiotherapy

2018 ◽  
Vol 10 (2) ◽  
pp. 33-38
Author(s):  
I V Vologdina ◽  
R M Zhabina ◽  
E G Poroshina ◽  
A A Stanzhevsky ◽  
A V Savelieva ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Risk Factors ◽  
Cardiovascular Risk ◽  
Elderly Patients ◽  
Cardiovascular Risk Factors ◽  
Cardiovascular Complications ◽  
Left Breast ◽  
Cardiac Insufficiency ◽  
Middle Aged ◽  
Elderly Age

The study was conducted to identify risk factors for cardiovascular complications in 38 women with HER2neu negative left breast cancer without severe cardiovascular pathology, related both to the clinical features of the patients and the treatmenbeing performed. Patients after radical mastectomy were hospitalized for chemotherapy (doxorubicin in a cumulative dose not exceeding 360 mg/m2) and 3D conformal radiation therapy on the left breast breast of chest radiation doses 39 Gy (equivalent to 48 Gy of normal functioning). Separation into groups was carried out depending on the age: from 20 to 59 years - 20 patients, from 60 to 74 years - 18 patients. It was revealed that the risk of cardiovascular complications in the Score Scale was significantly higher in elderly patients due to age, increased systolic blood pressure and hypercholesterolemia. These patients showed higher rates of BMI and abdominal obesity. The study of psychosocial factors has shown great importance of the transferred stress in the past. The patients of the second group showed high personal anxiety (55.4 ± 3.4, 95% CI 49,6-56,4). In 70% of middle-aged patients and 89% of elderly patients after chemotherapy and radiotherapy cardiotoxicity in the form of cardiac insufficiency of systolic and diastolic dysfunction and asymptomatic cardiac arrhythmias was revealed. (For citation: Vologdina IV, Zhabina RM, Poroshina EG, et al. Evaluation of cardiovascular risk factors in women with left breast cancer of middle-aged and elderly age at the stage of chemotherapy and radiotherapy. Herald of North-Western State Medical University named after I.I. Mechnikov. 2018;10(2):33-38. doi: 10.17816/mechnikov201810233-38).

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