scholarly journals Evaluation of agreement between clinical and histopathological diagnosis of subtype of leprosy by skin punch biopsy

2020 ◽  
Vol 13 (1) ◽  
pp. 4-8
Author(s):  
Suman Poudel ◽  
Sunita Ranabhat ◽  
Gita Pun
Keyword(s):  
Mycobacterium Leprae ◽  
Punch Biopsy ◽  
Lepromatous Leprosy ◽  
P Value ◽  
Histopathological Diagnosis ◽  
Cross Sectional ◽  
Moderate Agreement ◽  
Skin Punch Biopsy ◽  
Tuberculoid Leprosy ◽  
Granulomatous Diseases

Introduction: Leprosy is chronic granulomatous disease caused by Mycobacterium leprae. Clinically diagnosed cases of leprosy can be evaluated by punch biopsy. It can be classified according to Ridley and Jopling Classification. Objective: To study the different spectrum of leprosy and its Bacillary Index (BI), evaluate the agreement between clinical and histopathological diagnosis. Materials and Methods: This is a hospital based cross sectional retrospective study done for the period of 6 months from January to June 2019. The data were subjected to kappa analysis by using SPSS version 24 to see the agreement between clinical and histopathological diagnosis. Results: Out of 62 cases of clinically diagnosed cases of leprosy three (4.83%) cases turned out to be other granulomatous diseases. According to Ridley and Jopling classification, clinical and histopathological agreement was seen in 38 (61.29%) cases. Agreement of 100% was seen in Indeterminate leprosy (IL) and Borderline tuberculoid leprosy (BT). The BI was more in Lepromatous leprosy (LL), Borderline lepromatous (BL) whereas IL, BT and Tuberculoid leprosy (TT) showed less BI. Overall there was moderate agreement between clinical and histopathological diagnosis (kappa- 0.505) which was statistically significant (p value <0.05). Conclusion: There was moderate agreement between the clinical and histopathological diagnosis of subtype of leprosy. The Bacillary load was high in LL whereas least in TT and is determined by immune system.

scholarly journals Clinicohistopathological correlation of leprosy

2017 ◽  
Vol 7 (1) ◽  
pp. 1095-1102
Author(s):  
A Shrestha ◽  
S Chauhan ◽  
M Mathur
Keyword(s):  
Clinical Diagnosis ◽  
Clinical Information ◽  
Lepromatous Leprosy ◽  
P Value ◽  
Histopathological Diagnosis ◽  
Histopathological Correlation ◽  
The Social ◽  
Tuberculoid Leprosy

BACKGROUND: Leprosy is a chronic infectious granulomatous disease caused by Mycobacterium leprae. It is a spectral disease which is classified into five groups according to Ridley and Jopling based on clinical, histological, microbiological and immunological criteria. Adequate clinical information combined with bacilloscopy and histopathology is helpful not only in classification of different types of leprosy but also useful for management of the cases.METHOD: 50 cases of leprosy were examined and clinical data was recorded. Slit skin smears were stained with Ziehl Neelsen stain. Skin biopsy was stained with Hematoxylin-Eosin stain and Fite Farraco stain was performed to demonstrate acid fast bacilli. All patients were classified according to Ridley & Jopling classification. Clinico-histopathological correlation was done. Statistical analysis was done using SPSS (Statistical Package for the Social Sciences) 16.0.RESULTS: Most common histological type of leprosy was tuberculoid leprosy seen in 19(38%) cases followed by indeterminate leprosy. Overall clinico-histopathological correlation was seen in 39.58%. The correlation was highest in indeterminate and histoid leprosy (100%) followed by lepromatous leprosy (66.66 %%) and tuberculoid leprosy (50%). Slit skin smear showed bacilli in 12 out of 48 cases (25%) while biopsy showed bacilli in 16 out of 48 cases (33.3%).CONCLUSION: In the present study, clinical diagnosis did not correlate with histopathological diagnosis significantly (p value=0.04159). The study emphasizes the role of histopathological and bacilloscopic examination to aid the clinical diagnosis for accurate typing of leprosy cases then better management of the patient.

scholarly journals Clinico-histopathological correlation of skin biopsies in leprosy

2013 ◽  
Vol 3 (6) ◽  
pp. 452-458 ◽  
Author(s):  
U Manandhar ◽  
RC Adhikari ◽  
G Sayami
Keyword(s):  
Clinical Information ◽  
Lepromatous Leprosy ◽  
Cross Sectional ◽  
Histopathological Correlation ◽  
Granulomatous Lesions ◽  
Tuberculoid Leprosy ◽  
Special Stain ◽  
Different Types ◽  
Skin Biopsies

Background: In leprosy, there is a range of varied clinicopathologic manifestations and the diagnosis is made from adequate clinical information combined with bacilloscopy and histopathology which helps in diagnosing different types of leprosy and separating it from other granulomatous lesions. Aim of the study was to classify leprosy according to Ridley Jopling classification and perform the clinicopathological correlation. Materials and Methods: A cross sectional comparative study of skin biopsies of newly diagnosed leprosy recieved over a period of 18 months from January 2009 to June 2010 and clinicopathologic correlation was done along with special stain. Results: This study included 75 patients diagnosed clinically as leprosy. Skin biopsy revealed evidence of leprosy in 72 cases. Maximum number of patient clinically belonged to tuberculoid leprosy which constituted 25 (33%) cases followed by borderline tuberculoid 19 (25.33%). On the contrary, histologically borderline tuberculoid was the most common type (40%, n=30) cases and tuberculoid leprosy constituted (13.33%, n=10) cases. Three cases of clinically diagnosed tuberculoid leprosy showed no features of leprosy histologically. Clinical and histopathological correlation was seen in 34 cases (45.33%). The correlation was highest in borderline tuberculoid (63.15%) followed by borderline lepromatous and lepromatous leprosy. Slit skin smear was positive in 31 cases (43.05%). Fite Farraco stain was positive in 18 cases (25%). Conclusion: The classification of leprosy requires attention to the histopathological criteria and correlation with clinicalinformationand bacteriological examination so as to facilitate accurate therapy to prevent undesirable complication. DOI: http://dx.doi.org/10.3126/jpn.v3i6.8992   Journal of Pathology of Nepal (2013) Vol. 3, 452-458

scholarly journals Detection of Mycobacterium leprae DNA for 36kDa protein in urine from leprosy patients: a preliminary report

2004 ◽  
Vol 46 (5) ◽  
pp. 275-277 ◽  
Author(s):  
Om Parkash ◽  
Hari Bhan Singh ◽  
Subha Rai ◽  
Archna Pandey ◽  
Vishwa Mohan Katoch ◽  
...  
Keyword(s):  
Treatment Response ◽  
Preliminary Report ◽  
Mycobacterium Leprae ◽  
Lepromatous Leprosy ◽  
Healthy Individuals ◽  
Specific Pcr ◽  
Number Of Patients ◽  
Tuberculoid Leprosy ◽  
Leprosy Patients ◽  
First Time

We have searched for Mycobacterium leprae DNA for 36kDa protein in urine using a M. leprae specific PCR technique. A limited number of 16 patients (of which 11 belonged to lepromatous leprosy and five to tuberculoid leprosy) and eight healthy individuals were included for the present study. The number of urine samples positive by PCR were 36.4% (4/11) in lepromatous patients and 40% (2/5) in tuberculoid patients. None of the samples from healthy individuals was positive. To our knowledge, the results indicate, for the first time, the presence of M. leprae DNA in urine from leprosy patients. Another important finding obtained out of the study is that amongst treated patients 66.6% (4/6) were positive whereas amongst untreated only 20% (2/10) were positive. From the present indicative data it appears that treatment improves the PCR results with urine as a sample. Thus, the approach could prove to be useful for monitoring the treatment response of individual patients and needs to be further evaluated with a large number of patients.

scholarly journals Hubungan Pengetahuan dan Dukungan Keluarga terhadap Perawatan Diri Penderita Kusta di RSUP Dr. Sitanala Kota Tangerang

2021 ◽  
Vol 13 (3) ◽  
pp. 113-120
Author(s):  
Ainun Wulandari ◽  
Maisya Rivita
Keyword(s):  
Drug Therapy ◽  
Family Support ◽  
Self Care ◽  
Mycobacterium Leprae ◽  
Cross Sectional Study ◽  
P Value ◽  
Cross Sectional ◽  
Permanent Disability ◽  
Exact Test ◽  
Leprosy Patients

Abstrak Latar belakang: Kusta atau lepra disebabkan oleh Mycobacterium leprae dan dikategorikan sebagai penyakit menular. Kusta termasuk salah satu masalah kesehatan di beberapa negara. Disabilitas permanen dan gangguan kualitas hidup merupakan ancaman kesehatan bagi penderitanya jika tidak ditangani. Selain pengobatan dengan Multi Drug Therapy (MDT), penderita kusta perlu memperhatikan perawatan diri secara kontinyu seumur hidupnya. Perawatan diri ini dapat mencegah disabilitas dan juga memburuknya disabiltas pada penderita kusta. Studi ini ditujukan untuk mengetahui hubungan pengetahuan dan dukungan keluarga terhadap perawatan diri penderita kusta di RSUP Dr. Sitanala Kota Tangerang. Metode: Penelitian cross sectional ini dilakukan pada Juli 2020 melalui wawancara menggunakan kuesioner. Penelitian ini dilakukan di Poli Kusta RSUP Dr. Sitanala Kota Tangerang dengan responden sebanyak 83 orang dan dianalisis menggunakan uji Fisher’s Exact. Hasil: Berdasarkan hasil penelitian diketahui bahwa pengetahuan tidak memiliki hubungan terhadap perawatan diri penderita kusta di RSUP Dr. Sitanala Kota Tangerang (p-value=0,069) dan terdapat hubungan antara dukungan keluarga terhadap perawatan diri penderita kusta rawat di RSUP Dr. Sitanala Kota Tangerang (p-value = 0,003). Kesimpulan: Hasil penelitian menunjukkan bahwa penderita kusta yang memiliki pengetahuan baik ataupun kurang baik melakukan perawatan diri yang sama. Dukungan keluarga memiliki peranan penting dalam memotivasi penderita kusta untuk melakukan perawatan diri yang baik. Kata kunci: Kusta, Pengetahuan, Dukungan Keluarga, Perawatan Diri.   Abstract Background: Leprosy or leprosy is caused by Mycobacterium leprae and is categorized as an infectious disease. Leprosy is one of the health problems in several countries. Permanent disability and disruption quality of life are a health threat to sufferers if not treated. In addition to treatment with Multi Drug Therapy (MDT), selfocare must be carried out by leprosy patients continuously throughout their lives. This self-care can prevent disability and also a worsening of disability in patients with leprosy. This study was conducted to determine the relationship between knowledge and family support for self-care of leprosy patients at RSUP Dr. Sitanala, Tangerang City. Methods: A cross sectional study was performed during July 2020 by interview using questionnaires. This research was conducted at the Leprosy Poly Dr. Sitanala Central Hospital Tangerang City with 83 respondents and were analyzed using the Fisher’s Exact test. Result: The result showed that knowledge had no relationship with self-care of leprosy patients at Dr. Sitanala Hospital, Tangerang City (p-value = 0.069), while there was a relationship between family support for self-care of leprosy patients at Dr. Sitanala Hospital, Tangerang City (p-value = 0.006). Conclusion: The results showed that leprosy patients who had good or poor knowledge did the same self-care. Family support has an important role in motivating good self-care of leprosy patients. Key Words: Leprosy, Knowledge, Family Support, Self-Care.

scholarly journals Importance of Routine Histopathology of Gallbladder after Elective Cholecystectomy for Gallstones

2016 ◽  
Vol 22 (2) ◽  
Author(s):  
Umair Ahmed Khan ◽  
Munazza Iqbal ◽  
Imran Aslam ◽  
Khalid Masood Gondal ◽  
Shahid Alam
Keyword(s):  
Gallbladder Carcinoma ◽  
P Value ◽  
Histopathological Diagnosis ◽  
Continuous Variables ◽  
Stone Size ◽  
Cross Sectional ◽  
Significant Difference ◽  
Duration Of Disease ◽  
The Mean ◽  
Elective Cholecystectomy

Introduction:  Gallstones are the hard deposits in the gallbladder, which is a sac – like organ lying on the inferior surface of liver in the right upper quadrant of abdomen. Cholecystectomy is the first line surgical procedure to manage symptomatic gallstone. Carcinoma gallbladder carries worst prognosis of all cancer mortality and seen in patients with chronic cholecystitis due to cholelithiasis. The purpose of conductingthis study was to highlight the fact, that the histopathology of the gallbladder in Pakistan is only restricted to those specimens, which are associated with macroscopic abnormalities.Objective:  The frequency of gallbladder carcinoma in routine histopathology after elective Cholecystectomy for gallstones who did not show any macroscopic findings preoperatively.Material and Methods:  This cross sectional study of 250 patients of both gender aged between 18 – 60 years was conducted in surgical OPD/North Surgical Unit of Mayo Hospital, Lahore in one year duration from 01-01-2014 to 31-12-2014. The non-probability purposive sampling technique was used in this study. Informed consent was taken from all the patients. Their demographics like name, age, gender and address were noted. Open / laparoscopic cholecystectomy was performed depending upon patient’s choice. All gallbladder specimens, those with no obvious gross abnormalities were sent for histopathology (Gross findings, histopathological diagnosis). All data was recorded on a pre-designed proforma and analyzed using SPSS version 20. Mean and standard deviation were used to express the continuous variables like age, stone size and duration of disease. All qualitative variables like gender, number of stones and gallbladder carcinoma were presented in the form of frequency and percentages. Stratification was done for duration of disease, number of stone, size of stone and gender to address effect modifiers. Post stratification chi-square test was applied keeping P-value ≤ 0.05 as significant.Results:  In this study the mean age of the patients was 39.52 ± 12.38 years. Among 250 patients, 75 (30%) were males and 175 (70%) females. The mean duration of disease was 5.61 ± 2.75 months. Gallbladder carcinoma on routine histopathology after elective Cholecystectomy was observed in 18 (7.2%) patients whereas 232 (92.8%) patients did not have gallbladder carcinoma. All of the 18 patients who had carcinoma were females which showed a highly significant difference (p < 0.05). Among 153 cases with < 7 mm stone size, carcinoma was observed in 11 patients and in 97 cases with ≥ 7 mm stone size, carcinoma was observed in 7 cases. Among 124 cases with < 5 months of duration of disease, carcinoma was observed in 9 patients and in 126 cases with ≥ 5 months of duration of dis-ease, carcinoma was observed in 9 cases. Among 93 cases with < 2 stones, carcinoma was observed in 7 patients and in 157 cases with ≥ 2 stones, carcinoma was observed in 11 cases. Statistically insignificant difference was found between the duration of disease, number and size of stones and carcinoma of the patients (P > 0.05).Conclusion:  Although the frequency of gallbladder carcinoma on histopathology is low, but not negligible, therefore histopathology of gallbladder specimen is necessary to rule out carcinoma.

scholarly journals Clinicohistopathological Correlation in Leprosy

2012 ◽  
Vol 9 (4) ◽  
pp. 248-251 ◽  
Author(s):  
M C Mathur ◽  
R B K Ghimire ◽  
P Shrestha ◽  
S K Kedia
Keyword(s):  
Infectious Disease ◽  
Clinical Diagnosis ◽  
Histopathological Examination ◽  
Mycobacterium Leprae ◽  
P Value ◽  
Histopathological Diagnosis ◽  
Common Infectious Disease ◽  
Clinical Diagnoses ◽  
Leprosy Patients ◽  
Skin Biopsies

Background Leprosy is a chronic, infectious disease caused by Mycobacterium leprae. It is classified into five groups based on clinical, histological, microbiological and immunological criteria (Ridley & Jopling Classification). However, a great variation has been observed in the interpretation of histopathological examination ok skin biopsies and clinical presentation of the disease. Objective To correlate clinical diagnosis with histopathological diagnosis of leprosy patients in Nepal. Methods A retrospective hospital-based study was conducted among patients with all clinical types of leprosy, classified as per the Ridley-Jopling classification. Skin biopsies were taken from active lesions in all patients and were stained with Hematoxylin & Eosin stain and modified Fite-Ferraco stain for identification of Mycobacterium leprae. The histopathological findings were compared with clinical diagnoses. Results A total 156 patients were studied, out of which 84 (53.8%) males and 72 (46.1%) females between 8 and 86 years of age. The majority of patients 33 (23.57%) were in the age group of 21-30 years and least affected was children below 10 years 1(0.007%).Overall coincidence of clinical and histopathological diagnoses of classification was seen in 115 cases (80.4%). The maximum correlation (95.2%) was noted in LL patients (p value 0.000049) followed by BT(89.74%), TT (73.2%), BL(72.4%), BB(64.7%). Conclusion Leprosy still continues to be one of the common infectious disease in Nepal and skin biopsy is a useful tool in confirming the clinical diagnosis of leprosy as well as for the therapeutic guide. DOI: http://dx.doi.org/10.3126/kumj.v9i4.6338 Kathmandu Univ Med J 2011;9(4):248-51

scholarly journals Human Papillomavirus 16 lineage D is associated with high risk of cervical cancer in the Brazilian Northeast region

2021 ◽  
Author(s):  
Luís Felipe Leite Martins ◽  
Miguel Ângelo Martins Moreira ◽  
Rodrigo Alves Pinho ◽  
Neilane Bertoni ◽  
Shayany Pinto Felix ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Cervical Intraepithelial Neoplasia ◽  
Intraepithelial Neoplasia ◽  
P Value ◽  
Histopathological Diagnosis ◽  
Cross Sectional ◽  
Hpv 16 ◽  
Northeast Region ◽  
Human Papillomavirus 16 ◽  
Cancer Group

Abstract BackgroundLike HPV types, different lineages also appear to have different carcinogenic capabilities. Studies have shown that oncogenic HPV specific to the genotype lineage is associated with different risks for the development of cervical intraepithelial neoplasia (CIN2 / CIN3) and cervical cancer. This study aims to analyze the genetic diversity of HPV 16 genotype in cases of cervical intraepithelial neoplasia (CIN2/CIN3) and cervical cancer in women from the Northeast region of Brazil.Methods and ResultsA cross-sectional hospital-based study conducted in the Northeast region of Brazil from 2014 through 2016. In the sample, there were 196 cases of HPV-16 variant (59 cervical intraepithelial neoplasia - CIN2/CIN3 and 137 cases of cervical cancer). Difference of proportion test was used to compare groups of CIN2/CIN3 and cervical cancer by viral lineage (p-value <0.05) in respect to HPV-16 lineage prevalence.The percentage of lineage frequencies by histopathological diagnosis showed a borderline difference of lineage A in the CIN2/CIN3 group compared to the cervical cancer group (p = 0.053). In relation to lineage D, the proportion was higher in cancer cases (32.8%) compared to the CIN2/CIN3 group (16.9%), p-value of 0.023.ConclusionsHPV16 lineage A was the most frequent in both CIN2/CIN3 and cervical cancer samples, while lineage D predominated in cervical cancer, suggesting a possible association of HPV-16 lineage D with cervical cancer.

scholarly journals Comparison of the Accuracy of Papanicolaou Test Cytology, Visual Inspection With Acetic Acid, and Visual Inspection With Lugol Iodine in Screening for Cervical Neoplasia in Southeast Nigeria

2018 ◽  
pp. 1-9 ◽  
Author(s):  
John Egede ◽  
Leonard Ajah ◽  
Perpetus Ibekwe ◽  
Uzoma Agwu ◽  
Emmanuel Nwizu ◽  
...  
Keyword(s):  
Acetic Acid ◽  
Visual Inspection ◽  
Punch Biopsy ◽  
Cervical Neoplasia ◽  
P Value ◽  
Papanicolaou Test ◽  
Cross Sectional ◽  
Resource Limited ◽  
Significant Difference ◽  
Group 2

Purpose This study aimed to compare the accuracy of Papanicolaou test cytology, visual inspection with 5% acetic acid (VIA), and visual inspection with Lugol iodine (VILI) in the detection of premalignant and malignant lesions of the cervix. Materials and Methods This was a cross-sectional comparative study of 200 consenting participants at the Federal Teaching Hospital, Abakaliki over a 6-month period. All the participants had Papanicolaou test cytology. Subsequently, they were classified into two groups of 100 each through systematic random sampling: group 1 had VIA and group 2 had VILI. Thereafter, all the participants had cervical punch biopsy at the 6 and 12 o’clock cervical positions. Cervical punch biopsy was also done on the suspicious lesions of the cervix irrespective of their positions. The tests of validity of the three methods were calculated using the histology of the biopsy specimen as the gold standard. P value ≤ .05 was considered to be statistically significant. Results Among the VIA group, 19 (19%) had cervical epithelial abnormalities on Papanicolaou test cytology, and VIA was positive in 14 (14%). Histology results showed cervical neoplasia in 15 (15%) of the participants. Among the VILI group, 15 (15%) had cervical epithelial abnormalities on Papanicolaou test cytology, and VILI was positive in 19 (19%). Histology results showed cervical neoplasia in 15 (15%) of the participants. There was no significant difference in overall accuracy of Papanicolaou test cytology, VIA, and VILI. The overall accuracy of the Papanicolaou test cytology plus VIA was significantly more than Papanicolaou test cytology alone. Conclusion VIA or VILI can be used as a stand-alone cervical cancer screening test when compared with Papanicolaou test cytology, particularly in resource-limited settings. VIA can also complement Papanicolaou test cytology.

scholarly journals Penemuan Kasus Infeksi Kusta Subklinis pada Anak melalui Deteksi Kadar Antibodi (IgM) anti PGL-1

2015 ◽  
Vol 10 (2) ◽  
pp. 74
Author(s):  
Arif Sujagat ◽  
Fardhiasih Dwi Astuti ◽  
Eva Muslimawati Saputri ◽  
Annisa Sani ◽  
Agil Dwi Prasetya
Keyword(s):  
Random Sampling ◽  
Capillary Tube ◽  
Serological Test ◽  
Sampling Technique ◽  
Mycobacterium Leprae ◽  
Simple Random Sampling ◽  
P Value ◽  
Chi Square ◽  
Cross Sectional ◽  
Antibody Levels

AbstrakKusta merupakan penyakit menular kronis yang disebabkan Mycobacterium leprae. Indonesia menempati peringkat ketiga penyumbang kasus kusta terbanyak di dunia pada tahun 2012 – 2014. Kota Surabaya merupakan daerah endemis kusta. Penelitian ini bertujuan untuk deteksi dini kusta subklinis berdasarkan pengukuran kadar antibodi (IgM) anti PGL-1 dan mengetahui faktor-faktor yang berhubungan dengan kusta subklinis pada anak di Kota Surabaya. Penelitian analitik menggunakan desain potong lintang pada bulan April - Mei 2015. Populasi dilakukan penelitian adalah keluarga yang memiliki anggota penderita kusta. Sampel dipilih dengan teknik simple random sampling dan sebanyak 30 kepala keluarga terpilih melalui rapid school and village survey pada bulan April - Mei 2015. Pengumpulan data dengan wawancara menggunakan kuesioner. Spesimen diambil dari darah perifer di ujung jari menggunakan tabung kapiler dan kertas saring. Uji serologi di Laboratorium Leprosy Lembaga Penyakit Tropis Universitas Airlangga untuk mengetahui kadar antibodi spesifik kusta menggunakan metode ELISA. Hasil seropositif ditetapkan nilai ambang ≥ 245 u/ml menunjukkan kusta subklinis. Berdasarkan hasil uji serologi didapatkan delapan responden (26,7%) positif kusta subklinis. Hasil analisis dengan uji kai kuadrat menunjukkan riwayat kontak (nilai p = 0,034; RP = 4,500) dan lama kontak (nilai p = 0,028; RP = 5,182) merupakan faktor yang berhubungan dengan infeksi kusta subklinis pada anak. Pemeriksaan serologi kadar antibodi (IgM) anti PGL-1 digunakan dalam kegiatan skrining kusta subklinis.AbstractLeprosy is a chronic infectious disease caused by Mycobacterium leprae. Indonesia places the world’s third major leprosy case contributor. SurabayaCity is a leprosy-endemic area. This study aimed to early detect subclinicalleprosy based on measurement of anti-PGL-1 antibody levels (IgM) and to determine factors related to subclinical leprosy among children in SurabayaCity. This study was analitic using cross-sectional design. The study population was families having leprosy sufferers. Samples were selected by simple random sampling technique and 30 family heads were selected by rapid school and village survey on April – May 2015. Data was collected byinterview using questionnaire. Specimen was taken from peripheral bloodof fingertip using capillary tube and filter paper method. Serological test was conducted in Airlangga University Leprosy Laboratory of Institute of Tropical Diseases to determine leprosy-specific antibody levels using ELISAmethod. Seropositive result as cut off point determined ≥ 245 u/ml showed subclinical leprosy. Results of serological test showed eight respondents (26.7%) were positive suffering subclinical leprosy. Results of analysis using chi-square test showed contact record (p value = 0.034; RP = 4.500) and duration of contact (p value = 0.028; RP = 5.182) were factors related to subclinical leprosy infection among children. Serological test of anti-PGL-1 antibody levels (IgM) was used in subclinical leprosy-screening activity.

HUBUNGAN LAMA WAKTU MENDERITA STROKE DENGAN TINGKAT KEMANDIRIAN KLIEN DALAM MELAKUKAN AKTIVITAS PEMENUHAN KEBUTUHAN SEHARI-HARI

2018 ◽  
Vol 1 (2) ◽  
pp. 58
Author(s):  
Setia Budi ◽  
Ria Dila Syahfitri
Keyword(s):  
Data Analysis ◽  
Univariate Analysis ◽  
Sampling Technique ◽  
P Value ◽  
Cross Sectional ◽  
Stroke Incidence ◽  
Bivariate Data ◽  
Cross Sectional Design ◽  
Interviewing Techniques ◽  
Need For Rehabilitation

The rate of stroke incidence is about 200 per 100,000 people throughout the world. This study aims to determine the Relation Suffer Stroke With Independence Level In Neurology Polyclinic TK II DR Ak Gani Palembang Year Hospital 2017. The research method used is descriptive quantitative with cross sectional design that is done by interviewing techniques with questionnaires on 42 respondents with Accidental sampling technique. This research was conducted in August 2017. Data analysis used is univariate data analysis and bivariate data analysis with one way anova test result. The results of univariate analysis showed that the duration of the respondents suffering from stroke was between 2.10 years to 3.38 years. Also found that most respondents were at the level of independence f; independent, except bathing, dressing, moving, and one other function with a total of 12 respondents. The results showed that there was a significant relationship between the long suffering stroke with the level of independence with the value of p value 0.025. For that the need for rehabilitation to patients and families of patients in order to help improve the independence of stroke patients in doing their daily activities. Keywords : Long Suffer Stroke, Level of Independence

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