scholarly journals Synthesis of a hydrophilic derivative of ecdysterone and development of its water-soluble form

2021 ◽  
Vol 104 (4) ◽  
pp. 138-148
Author(s):  
A.M. Kozhanova ◽  
◽  
B.S. Temirgaziyev ◽  
A. Zhanarbek ◽  
B.I. Tuleuov ◽  
...  
Keyword(s):  
Raw Materials ◽  
Chemical Shifts ◽  
Stoichiometric Composition ◽  
Water Soluble ◽  
Soluble Form ◽  
Nmr Studies ◽  
Polar Solvents ◽  
Plant Raw Materials ◽  
Pharmaceutical Plant ◽  
First Time

The article presents materials on the isolation of ecdysterone substance from medicinal plant raw materials Silene wolgensis (Hornem.) Bess. ex. Spreng (Volga smolyovka). For the first time, the optimization of the method for ecdysterone substance obtaining from the aboveground part of the superconcentrator of phytoecdysteroids of the Silene wolgensis was carried out and based on it a pilot industrial regulation for the isolation of ecdysterone and an encapsulated water-soluble form were developed. It was found, that the interaction of the substrate molecule and the clathrate forms a substance that can dissolve in water and other more polar solvents, thereby solving the problem of bioavailability of the main hydrophobic drug. The method developed for producing the substance ecdysterone and its water-soluble encapsulated with β-cyclodextrin form was implemented into production at the Karaganda pharmaceutical plant. NMR studies of changes in the chemical shifts of protons of substrates and receptors illustrated that ecdysterone interacts with β-cyclodextrin to form supramolecular inclusion complexes with stoichiometric composition of 1:1

scholarly journals Assessing protopectin transformation potential of plant tissue using a zoned criterion space

2020 ◽  
Vol 8 (2) ◽  
pp. 349-361
Author(s):  
Vladimir Kondratenko ◽  
Tatyana Kondratenko ◽  
Andrey Petrov ◽  
Georgy Belozerov
Keyword(s):  
Boundary Conditions ◽  
Plant Tissue ◽  
Raw Materials ◽  
Water Soluble ◽  
Biologically Active ◽  
Plant Raw Materials ◽  
Criterion Space ◽  
Transformation Potential ◽  
Fragmentation Potential ◽  
Pectin Substances

Introduction. The existing diversity of plant raw materials and products predetermine the prospects of studying their potential as sources of pectin substances. However all current classifications are either fragmented or inconsistent. Study objects and methods. Our theoretical ivestigation aimed to develop an adequate classification for all taxa of plant origin, as well as their tissues and derivatives as pectin-containing materials. We developed criteria for assessing transformation potential of the protopectin complex based on the mass fractions of biologically active non-uronide components, native water-soluble pectin, the protopectin complex, and pectin substances. Individual boundary conditions were based on individual pectin potential, protopectin fragmentation potential, and pectin isolation potential. Results and discussion. Based on the boundary conditions, we defined an universal criterion space that included a set of points M in the coordinates expressed by three main criteria. According to individual boundary conditions, the criterion space was divided, or zoned, into four domains corresponding to protopectin fragmentation potential. They were characterized by: 1) lack of pectin potential, 2) ineffective protopectin fragmentation, 3) ineffective isolation of fragmentation products, and 4) effective isolation. Finally, we developed a generalized algorithm to determine the location of points M[μ1, μ2 , μ3 ] in the zoned criterion space, characterizing the plant tissue. Conclusion. Our approach can be used to assess any plant tissue for its protopectin transformation potential, which determines the technological influence on its pectin potential. This approach is universal, i.e., applicable to both plant tissue and its derivatives.

scholarly journals THE SWEET ICES FOR PREGNANT WOMEN

2019 ◽  
Vol 13 (1) ◽  
Author(s):  
J. Kozonova ◽  
L. Telegenko ◽  
A. Salavelis
Keyword(s):  
Pregnant Women ◽  
Raw Materials ◽  
Chromatographic Study ◽  
Plant Raw Materials ◽  
Daily Food ◽  
Sodium Magnesium ◽  
Magnesium Salts ◽  
First Time ◽  
Average Woman ◽  
Acid Index

Daily food consumption norms of an average woman and a pregnant woman have been analysed. It has been established that in a pregnant woman’s diet, it is necessary to increase the content of proteins, fibre, vitamins C, E, D, PP, and B, and reduce fats, carbohydrates (easily digestible), vitamins B5 and H, sodium, magnesium, salts, and water. Taking into account the above-mentioned requirements, eight recipe compositions of sweet ices based on plant raw materials have been suggested. The recipes were selected by linear programming using MS Excel. The products have a low calorific content (26–137 kcal per 80 g), and an increased nutritional value (due to vitamin C, carotene, etc.). For the first time, cereals, various types of seeds, nuts, have been put into the recipe of sweet ices, as well as raw materials, which eliminate physiological complications during pregnancy. The products developed differ in their composition and are made without sugar. However, some recipes include small quantities of honey as it is highly palatable. The chemical composition of the new sweet products has been studied and analysed in details and sugar/acid indices have been calculated. The developed ices have a slightly acidic taste or no acidity at all, which corresponds to the values of sugar/acid indices 13.4–26.6, while the sample from the store, selected for comparison, contains a large amount of sugars, as evidenced by the cloying taste and high sugar/acid index (more than 30). The source of fatty acids in sweet ice for pregnant women Joy is almond nuts. The results of the chromatographic study have shown that this product as for the quantitative fatty acid composition, meets the current requirements. We recommend introducing the sweet ice manufacture technology on the equipment already in use in canneries. The products are formed (poured into moulds where wooden sticks are then inserted) in a Hassia machine. One of the main operations, freezing, is done in a quick freezer GyroFreze. We also recommend manufacturing sweet ices using existing restaurant equipment.

27Al-MAS-NMR-Untersuchungen des thermischen Abbaus von NH4Al(SO4)2·12H2O / 27Al-MAS-NMR Studies on the Thermolysis of NH4Al(SO4)2· 12H2O

1991 ◽  
Vol 46 (11) ◽  
pp. 1515-1518 ◽  
Author(s):  
Gerhard Wegner ◽  
Gert Blumenthal ◽  
Dirk Müller ◽  
Dirk-Henning Menz ◽  
Antje Schmalstieg
Keyword(s):  
Nmr Spectroscopy ◽  
Structural Changes ◽  
Chemical Shifts ◽  
Mas Nmr ◽  
Nmr Studies ◽  
High Stage ◽  
27Al Mas Nmr ◽  
High Resolution Nmr ◽  
First Time

Products of the thermolysis of NH4Al-alum were prepared under dried air and characterized by X-ray powder diffraction, thermogravimetry, and for the first time by solid-state 27Al-MAS-NMR spectroscopy. It was found, that high resolution NMR spectroscopy is applicable to follow up the thermal decomposition and to indicate even minor structural changes. 27Al-MAS-NMR spectra show peaks with characteristic chemical shifts for octahedral Al-units up to a high stage of thermolysis. During the decomposition of Al2(SO4)3 to γ-Al2O3 we again observed three-peak spectra with the specific signal at ≈ 35 ppm for penta-coordinated Al ions as recently proved for the thermolysis of AlCl3 · 6 H2O.

scholarly journals METHODS OF QUANTITATIVE AND QUALITATIVE DETERMINATION OF ARABINOXYLANS IN CEREALS (REVIEW)

2021 ◽  
pp. 27-43
Author(s):  
Lilia Firdavisovna Gilmullina ◽  
Mira Leonidovna Ponomareva ◽  
Sergey Nikolayevich Ponomarev ◽  
Gul'naz Suleymanovna Mannapova
Keyword(s):  
Raw Materials ◽  
Water Soluble ◽  
Simple Method ◽  
Deep Impact ◽  
Plant Raw Materials ◽  
Cereal Plant ◽  
Main Components ◽  
Cereal Plants ◽  
Qualitative Determination

Arabinoxylans (AXs) – non-starch polysaccharides (NSPs)  is one of the most discussed main components contained in all parts of cereal plants. AXs combine bioactive and technological functions. As dietary fibres, they have physiologically beneficial properties for human health. AXs are water-soluble and insoluble in water. The structure, structure, quantity and properties of AXs depend on which part of the grain or cereal plant is extracted and which method of isolation is used. There are many different methods of preliminary and deep impact aimed at extraction of AXs from plant raw materials. The use of a simple method or complex treatment for quantitative and qualitative determination of AXs depends on objectives and possibilities. The overview provides data on AXs content of different crops, depending on the extraction method. The main classical methods of AXs extraction, their advantages, disadvantages, and possible limitations of use are described. The variants of calculation of the quantitative AXs content used by different authors are separately considered.

Composite Material Based on Plant Raw Materials

2019 ◽  
Vol 974 ◽  
pp. 406-412
Author(s):  
E.A. Khadykina ◽  
Z.A. Meretukov
Keyword(s):  
Lightweight Concrete ◽  
Raw Materials ◽  
Soluble Sugars ◽  
High Strength ◽  
Water Soluble ◽  
Walnut Shell ◽  
Global Trends ◽  
Large Cities ◽  
Plant Raw Materials ◽  
Traditional Natural

Modern global trends show the preferred low-rise construction, even in large cities. Lightweight concrete is the most common material for low-rise construction. Existing lightweight concrete with the wood residues addition have several disadvantages due to the properties of the aggregate. In the southern regions of Russia, walnut grows in large quantities. Only a small part of the shell is processed, the rest is buried in the ground or burned. The proposed aggregate from crushed walnut shell has several advantages compared to the traditional natural organic fillers: low water demand and decay, high strength. The nutshell in the composition has sugars, which are the cement poisons, there are no data in the literature on the crushed shell technical characteristics. Thus, it is required to determine the crushed shell technical characteristics, to choose a processing method reducing the water-soluble sugars amount in the shell, to select the lightweight concrete composition, ensuring its optimal characteristics. The new kind of lightweight concrete will have characteristics different from existing analogues.

scholarly journals Interrelationships among selected essential elements in medicinal plant raw materials and their water-extractable forms

2013 ◽  
Vol 59 (2) ◽  
pp. 46-58
Author(s):  
Paweł Konieczyński ◽  
Marek Wesołowski
Keyword(s):  
Medicinal Plant ◽  
Raw Materials ◽  
Principal Component ◽  
Essential Elements ◽  
Water Soluble ◽  
Plant Materials ◽  
Plant Raw Materials ◽  
Plant Parts ◽  
Plant Samples ◽  
Water Extractable

Summary In the study, the relationships were investigated among N, P, Fe, Zn, Mn and Cu, in medicinal plant raw materials (herbal bags) and their water-soluble chemical forms in infuses. 42 independent samples of plant materials were chosen, represented by different morphological plant parts as herbs, leaves, flowers and fruits. The elements were determined by UV/Vis spectrometry (non-metals), and FAAS (metallic elements) after previous mineralization of plant samples (total concentrations), and directly in herbal teas (water-extractable forms). Most frequently the correlations between non-metals and Zn and Mn occurred, both between their total contents the water-extractable forms. Statistically significant correlations were also found in pairs: Zn-Mn, Fe-Zn, Mn-Fe, and Cu-Zn. Application of multivariate analysis revealed that cluster analysis grouped the studied samples into clusters with similar levels of the analyzed elements, and principal component analysis allowed the identification of water-extractable Zn, P-PO4 and water-extractable Cu as the most crucial factors determining the differentiation of the studied plant samples.

scholarly journals Chemical Composition of Medicinal Plants Growing Under Conditions of Anthropogenic Load (On the Example of the Kursk Region)

2020 ◽  
Vol 6 (4) ◽  
pp. 89-97
Author(s):  
S.A. Kurbatov ◽  
◽  
V.M. Zubkova ◽  
◽  
Keyword(s):  
Heavy Metals ◽  
Betula Pendula ◽  
Raw Materials ◽  
Biologically Active ◽  
Tilia Cordata ◽  
Plant Raw Materials ◽  
High Level ◽  
First Time ◽  
Kursk Region ◽  
Active Substances

in the conditions of the Kursk region, the analysis of soil samples and plant samples for the content of heavy metals was carried out. It is established that the soils of the studied areas are classified as having a high level of pollution in terms of their content. The priority pollutants of the soil are Pb, Zn, Cd, Cr, Ni, and Cu, the supply of which is mainly associated with the enterprises operating in this territory. The content of heavy metals in medicinal plant raw materials is estimated. For the first time, depending on the biological characteristics of Tilia cordata, Betula pendula, Plantago major, Urtica dioica, Achillea millefollium, data on the content of biologically active substances in conditions of technogenic pollution are presented, and the antioxidant activity of plants in areas characterized by various anthropogenic loads is studied.

scholarly journals FLAVONOIDS FROM THE BUDS OF THE HORSE CHESTNUT (AESCULUS HIPPOCASTANUM L.)

2020 ◽  
pp. 123-129
Author(s):  
Vladimir Aleksandrovich Kurkin ◽  
Pavel Viktorovich Belov
Keyword(s):  
Medicinal Plant ◽  
Raw Materials ◽  
Uv Spectroscopy ◽  
Raw Material ◽  
Aesculus Hippocastanum ◽  
Horse Chestnut ◽  
Plant Raw Materials ◽  
Wide Range ◽  
New Type ◽  
First Time

The buds of horse chestnut (Aesculus hippocastanum L., Hippocastanaceae family) is a new promising species of medicinal plant raw material. The prospect of studying the buds of this plant is due to the content of flavonoids in them, which have a wide range of pharmacological effects. Flavonoids are interesting for their capillary-strengthening action, which allows them to be used in the treatment of chronic venous insufficiency. This fact is consistent with the practice of using drugs from other organs of horse chestnut (seeds, leaves) as venotonic and angioprotective drugs. In addition, flavonoids are also characterized by antioxidant, anti-inflammatory, antimicrobial and antifungal activity. The actuality of the study of horse chestnut buds as a new type of medicinal plant material is also supported by the need to develop of the new effective and safe drugs based on the raw materials of this plant. The aim of this study was to determine the flavonoid composition of the buds of Aesulus hippocastanum. In the course of the work from the buds of horse chestnut by the method of column chromatography on silica gel L 100/160 was for the first time there were isolated and characterized using 1H-NMR, 13C-NMR, UV spectroscopy and mass spectrometry the flavonoid compounds rhamnocitrin (7-O-methylkaempferol), and accompanying 7,4′-dimethylkaempferol. The dominant and diagnostic significant flavonoid for the horse chestnut buds is rhamnocitrin. The results indicate the prospects for further study of the buds of the horse chestnut as a new type of medicinal plant raw materials.

scholarly journals Intensification of Polysaccharides Extraction from Plant Raw Materials under the Influence of Electric Current

2021 ◽  
Vol 57 (5) ◽  
pp. 66-77
Author(s):  
А.P. Malyushevskaya ◽  
◽  
V.N. Tsurkin ◽  
А.V. Ivanov ◽  
А.N. Yushchishina ◽  
...  
Keyword(s):  
Energy Consumption ◽  
Electric Current ◽  
Raw Materials ◽  
Extraction Process ◽  
Water Soluble ◽  
Biologically Active ◽  
Processing Temperature ◽  
Plant Raw Materials ◽  
Convection Heating ◽  
Pulsed Electric Current

The article presents the results of the studies of the intensification of the processes of extraction of water-soluble polysaccharides from plant raw materials – medicinal hyssop (Hyssopus officialis L.) under the action of an electric current. The effect of direct, alternating, and pulsed electric currents on the degree of polysaccharides extraction was studied in comparison with the traditional pharmacopoeiсal method. It is shown that the energy consumption for the extraction process, intensified by a pulsed electric current, is significantly lower compared to extraction by convection heating. At the same time, the use of electric current makes it possible to reduce the limiting processing temperature from 70 °С to 40 °C, this will allow in the future to obtain not only aqueous, but also aqueous-alcoholic and alcoholic extracts, and, consequently, to extract biologically active non-soluble in water substances.

scholarly journals Identification of anise (Anisum vulgare Gaertn.) herbs by morphological and anatomical characteristics

2021 ◽  
Vol 14 (1) ◽  
pp. 39-44
Author(s):  
S. V. Kolisnyk ◽  
T. M. Gontova ◽  
U. A. Umarov ◽  
K. R. Hordiei
Keyword(s):  
Antibacterial Effect ◽  
Raw Materials ◽  
Microscopic Analysis ◽  
Anatomical Structure ◽  
Biologically Active ◽  
Professional Literature ◽  
Plant Raw Materials ◽  
Naked Eye ◽  
Normative Documentation ◽  
First Time

The fruits of anise contain different classes of biologically active compounds, due to which they have antidepressant, antiperoxidant, antidiabetic effect; extracts of this plant have an antibacterial effect. Professional literature lacks information on the chemical composition of anise herbs and prospects for their use in medicine. The aim of the work is to study of the morphological and anatomical structure of the aboveground organs of anise and to establish of macro- and microscopic diagnostic characters necessary for the identification of the plant raw materials. Materials and methods. Anise herbs consisting of stems, leaves flowers, and unripe fruits were used for the study. Fresh and dried raw materials were macroscopically analyzed with the naked eye and using a magnifying glass (×10). Studies of transverse and longitudinal sections, epidermis and surface preparations were performed using conventional techniques: with microscopes MBS 9, MS 10 (glasses ×5, ×10, ×15, lenses ×10, ×40), Micromed XS-4130 (eyepiece WF15X, lenses ×40/0.65, ×10/0.25) with a photomicrographic attachment. The micrographs were taken with Samsung PL50 camera. Results. As a result of the macro- and microscopic analysis, diagnostic properties of anise herbs were established. Conclusions. It is for the first time that macro- and microscopic characteristics of anise herbs were studied, which confirms the identity of raw materials. The obtained results will be used for the development of domestic normative documentation on anise herbs raw materials.

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