scholarly journals Reinforcing Risk Perception to Induce Exercise Intention: Role of Systematic Interaction from Social Marketing Perspectives

2019 ◽  
Vol IV (II) ◽  
pp. 24-38
Author(s):  
Farooq Ahmad ◽  
Muhammad Nawaz Qaisar ◽  
Syed Ali Raza Hamid
Keyword(s):  
Risk Perception ◽  
Fear Appeals ◽  
Control Group ◽  
Fear Appeal ◽  
Treatment Conditions ◽  
And Control ◽  
Exercise Intention ◽  
The Impact ◽  
The Relationship

The study examined the relationship between systematic interaction, fear appeals, and exercise intention using group-centered and participatory approaches. The longitudinal experimental design was used to understand the phenomenon of fear appeals (risk perception) for adopting sustained physical activities. The sample comprised two treatment conditions i.e. experimental group and control group to measure the impact of interventions for verification of the proposed conceptual model. The findings indicate that risk perception mediated the relationship between systematic interaction and exercise intention. Moreover, systematic interaction has a positive effect on risk perception and exercise intention. The findings conceptually advance the fear appeal theory with a new lens using a participatory paradigm to augment sustained behavior change. We advocate that use of systematic interaction adds value in expanding the scope of a theoretical base for marketing.

scholarly journals The Morphology of Cross-Beaks and BMP4 Gene Expression in Huiyang Bearded Chickens

Animals ◽  
2019 ◽  
Vol 9 (12) ◽  
pp. 1143
Author(s):  
Yuyu Hong ◽  
Yuchang Pang ◽  
Haiquan Zhao ◽  
Siyu Chen ◽  
Shuwen Tan ◽  
...  
Keyword(s):  
Genetic Basis ◽  
Control Group ◽  
Jaw Bones ◽  
Lower Jaw ◽  
Morphogenetic Protein ◽  
Parietal Bones ◽  
And Control ◽  
The Impact ◽  
The Relationship

Bird beaks are important for biological purposes such as food intake, removing parasites, and defining phenotypic attributes. Cross-beaks are a threat to poultry health and are harmful to productivity, wasting some units in the poultry industry. However, there is still limited research on subtypes of cross-beaks and the genetic basis of cross-beaks as well. Here, we described the subtypes of cross-beaks in terms of left or right and upper or lower jaw bones. We evaluated the impact of cross-beaks on craniofacial bones and figured out the relationship between bone morphogenetic protein 4 (BMP4) and the development of craniofacial bones in Huiyang bearded chickens. We identified five typical subtypes of cross-beaks by morphological assessment and X-ray scanning. We found that cross-beaks caused certain changes in the facial bone morphology, including changes to the length and width of the bone around the ocular area (p < 0.05). The relative expressions of BMP4 in lacrimal, mandible, premaxilla, frontal, and parietal bones were significantly higher in the severe cross-beak group, followed by that of the medium cross-beak group, weak cross-beak group, and control group (p < 0.05). Overall, we constructed a generally applicable method to classify cross-beaks in term of the angle. The skeleton around the ocular area was affected by the cross-beak. The expression levels of BMP4 in craniofacial bones may provide insight to potential role of BMP4 in the development of cross-beaks.

scholarly journals THE ROLE OF INFLAMMATION AND COAGULATION CASCADE IN THE PATHOGENESIS OF ATRIAL FIBRILLATION

ASJ. ◽  
2020 ◽  
Vol 3 (41) ◽  
pp. 8-10
Author(s):  
L. Hazarapetyan ◽  
S. Grigoryan ◽  
A. Sarksyan
Keyword(s):  
Atrial Fibrillation ◽  
Coagulation Cascade ◽  
Control Group ◽  
Atrial Remodeling ◽  
Inflammation Markers ◽  
Reactive Protein ◽  
Gender And Age ◽  
The Impact ◽  
The Relationship

Introduction: Atrial fibrillation (AF) is associated with prothrombotic or hypercoagulable states, various inflammation markers such as interleukin-6 (IL-6) and hsC-reactive protein (hsCRP) have also been associated with AF. The aim of this study is to investigate the relationship between inflammation markers and the prothrombotic state in the setting of AF and the impact on outcome in patients with AF. Methods: We observed 141 patients with non-valvular AF. As a control group patients similar in gender and age without AF were examined. Clinical, instrumental and laboratory tests were performed on the observed patients. The markers of the coagulation cascade (TF and F) and of inflammatory markers (hsCRP and IL-6) were studied additionally by ELISA on the analyzer "Stat Fax 303 Plus". Studies were conducted using SPSS 13.0 and EXCEL-2013. Results: The obtained results showed that compared to the control group, AF patients had significantly higher levels of IL-6 (p = 0.043), hsCRP (p = 0.002), TF (p = 0.026), and F (p = 0.025). Moreover, levels of hsCRP were higher among AF patients at "high" risk of stroke by CHA2DS2-VASc Score (p = 0.003). Besides, the levels of hsCRP and IL-6 were markedly elevated in patients with dilated left atrium (p = 0.001), poorly functioning left atrial appendage (p = 0.023) and longer duration of AF (p = 0.002). Conclusion: We have demonstrated that the increased plasma levels of IL-6 and hsCRP are related to indices of the coagulation cascade and contribute to structural atrial remodeling in patients with AF.

scholarly journals Shareholding Patterns and its Impact on Firm Performance: A Contemporary Study of Indian NIFTY 50 Companies

2018 ◽  
Vol 7 (1) ◽  
pp. 31-41
Author(s):  
Raghu Katragadda ◽  
A. Sreeram
Keyword(s):  
Firm Performance ◽  
Empirical Study ◽  
Vital Role ◽  
Monitoring And Control ◽  
Book Value ◽  
Contemporary Study ◽  
And Control ◽  
The Impact ◽  
The Relationship

Ownership structure or the stakeholder structure of an organization often play significant role in operations decision, monitoring and control. This as a result possesses influences over process and hence performance. On the other hand, the role of stakeholders and respective conflict of interests can also be not ruled out. Under such circumstances, assessing the impact of organizational structure or stakeholder pattern and firm performance becomes inevitable to assess. In addition, the relationship between the investment pattern and respective conflicts of interests is inevitable to be examined. To ensure investment security corporate governance has played vital role that suggests assessing the inter-relationship between the stakeholder pattern and firm performance. With this motivation, in this paper an empirical study has been done to examine the impact of internal shareholding patterns on the associated firm’s performance. In this paper we have performed an empirical study where the aforementioned relationship has been examined for Indian listed NIFTY 50 companies for the duration of the financial year 2011 to 2016. Our empirical results provide evidence that insider shareholding is positively and significantly related to the firm performance as measured by market capitalization; market value by book value and Tobin’s Q.

scholarly journals Study The Overprescription Of Proton Pump Inhibitors And Their Relation With Recurrent Community Aquired Infections In Outpatient Refilled Prescriptions Of Chronic Diseases Patients

2016 ◽  
Vol 12 (6) ◽  
pp. 116
Author(s):  
Aysha Abedalhameed Alkhalaylah ◽  
Maisan Mahmoud Hayajneh ◽  
Shireen Imad Hijazeen ◽  
Tahanie Ali Alqhewii ◽  
Eva Raji Haddad ◽  
...  
Keyword(s):  
Proton Pump Inhibitors ◽  
Proton Pump ◽  
Neutrophil Count ◽  
Inflammatory Biomarkers ◽  
Control Group ◽  
Study Group ◽  
Study Participants ◽  
And Control ◽  
The Relationship

Background: proton pump inhibitors are widely used worldwide and studies have demonstrated that the use of PPIs to be associated with various diseases such as several types of infection. Study objectives: to explore the effect of using PPIs on patients through studying some inflammatory biomarkers including WBC, neutrophil count, ESR, CRP, and IL-6. Methods and subjects: a retrospective study design was followed to collect data from study participants. The study included 62 patients receiving PPIs and 60 persons without being prescribed for PPIs. A working sheet was created for each patient and included the following information: age, WBC, neutrophil count, ESR, CRP, and IL-6. Data analysis was carried out using SPSS version 20. The relationship between variables was tested using independent T test. Significance was considered at alpha level < 0.05. Study findings: age was not varied significantly between study group and control group. All inflammatory biomarkers under study were significantly elevated in study group compared with control group. Conclusions: the findings of the present study showed that the use of PPIs was associated significantly with increased inflammatory biomarkers. We think that health settings should pay much attention to the role of pharmacists and pharmacy doctors to increase the awareness about the use of PPIs.

scholarly journals Association of gestational diabetes mellitus with changes in gut microbiota composition at the species level

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Fang Chen ◽  
Yu Gan ◽  
Yingtao Li ◽  
Wenzhi He ◽  
Weizhen Wu ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Gestational Diabetes ◽  
Gut Microbiota ◽  
Gestational Diabetes Mellitus ◽  
Fasting Glucose ◽  
Species Level ◽  
Control Group ◽  
And Control ◽  
The Relationship

Abstract Background Gestational diabetes mellitus (GDM), a common endocrine disorder with rising prevalence in pregnancy, has been reported to be associated with alteration of gut microbiota in recent years. However, the role of gut microbiome in GDM physiopathology remains unclear. This pilot study aims to characterize the alteration of gut microbiota in GDM on species-level resolution and evaluate the relationship with occurrence of GDM. Methods An analysis based on 16S rRNA microarray was performed on fecal samples obtained from 30 women with GDM and 28 healthy pregnant women. Results We found 54 and 141 differentially abundant taxa between GDM and control group at the genus and the species level respectively. Among GDM patients, Peptostreptococcus anaerobius was inversely correlated with fasting glucose while certain species (e.g., Aureimonas altamirensis, Kosakonia cowanii) were positively correlated with fasting glucose. Conclusions This study suggests that there are large amounts of differentially abundant taxa between GDM and control group at the genus and the species level. Some of these taxa were correlated with blood glucose level and might be used as biomarkers for diagnoses and therapeutic targets for probiotics or synbiotics.

scholarly journals The Role of Perceived Competence and Risk Perception in Cycling Near Misses

2019 ◽  
Author(s):  
Gabriele Prati ◽  
Víctor Marín Puchades ◽  
Filippo Fassina ◽  
Federico Fraboni ◽  
Marco De Angelis ◽  
...  
Keyword(s):  
Risk Perception ◽  
Perceived Control ◽  
Perceived Competence ◽  
Near Miss ◽  
Mixed Traffic ◽  
Near Misses ◽  
Common Causes ◽  
And Control ◽  
The Relationship

Cyclists’ accidents account for a relatively large proportion of road fatalities and this proportion is increasing. Moreover, research suggests that crashes can be predicted by near misses, based on the assumption that they share common causes. Also in the cycling domain it has been suggested that near miss incidents may provide ‘early warnings’ of situations or behaviours that could lead to crashes. The aim of this study was to investigate the role played by perception of risk and control on the exposure to risky situations, such as the involvement in mixed traffic. We administered a questionnaire to 298 Italian cyclists measuring perceived competence (i.e. perceived control and overconfidence), risk perception of interactions with cars, bicycle use, avoidance of mixed traffic and recent experiences of near misses. Path analysis using Bayesian estimation showed that perceived control, mediated by overconfidence, had a positive indirect effect on bicycle use and a negative one on avoidance of mixed traffic, while it acted as a moderator in the relationship between risk perception of interaction with cars and avoidance of mixed traffic. Furthermore, the mediation paths revealed the indirect effects of perceived control on near misses through exposure. Results highlighted the importance of considering the role of individuals’ perception of their ability to cycle with regard to near misses and provided new insight on how cyclists regulate their behaviour, as well as how such behaviour leads to different safety outcomes. Results have implications regarding theory, infrastructure and the application of new safety technologies.

scholarly journals Adamalysines as Biomarkers and a Potential Target of Therapy in Colorectal Cancer Patients: Preliminary Results

2019 ◽  
Vol 2019 ◽  
pp. 1-7 ◽  
Author(s):  
Katarzyna Walkiewicz ◽  
Joanna Strzelczyk ◽  
Dariusz Waniczek ◽  
Krzysztof Biernacki ◽  
Małgorzata Muc-Wierzgoń ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Cancer Patients ◽  
Distant Metastases ◽  
Serum Levels ◽  
Control Group ◽  
Colorectal Cancer Patients ◽  
And Control ◽  
The Relationship ◽  
Increased Activity

Colorectal cancer is one of the most common cancers in the world. Due to its still undetermined pathogenesis, we are searching for signaling pathways that are important in the development of colorectal cancer. In this article, we present results of study on the role of ADAM proteins in colorectal cancer. The study included 85 adult colorectal cancer patients (48 men, 37 women) and 25 patients in the control group (after diagnostic colonoscopy—without cancer). During hospitalization, a serum sample (3 cm3) was collected from the study and control group, anthropometric measurements were conducted and others clinical data were analyzed. In the serum ADAM10, 12, 17, and 28, protein concentrations were determined and, in the next step, examined the relationship between ADAMs concentrations and selected clinical parameters in both groups. The analysis showed that serum levels of ADAM10 and ADAM28 are significantly higher in patients with colorectal cancer and correlate with histopathological grading and with presence of distant metastases. Moreover, noticed the trend to correlate concentrations of adamalysines with higher BMI score. One of the functions of adamalysines is the activation of growth factors involved in cancer, including IGF and TNFα. The increased activity of adamalysines in patients may play a role in the pathogenesis of colorectal cancer. Our study highlights the prevalence of metabolic disorders in the group of patients with diagnosed CRC, and this cancer seems to be a further complication of obesity.

scholarly journals Combination therapy of Tocilizumab and steroid for COVID-19 patients: A meta-analysis

2021 ◽  
Author(s):  
Mahmood moosazadeh ◽  
Tahoora Mousavi
Keyword(s):  
Combination Therapy ◽  
Meta Analysis ◽  
Control Group ◽  
Mechanical Ventilators ◽  
Risk Of Death ◽  
And Control ◽  
The Impact ◽  
Pro Inflammatory Cytokines

Abstract BackgroundThe coagulation markers, pro-inflammatory cytokines (such as IL-2R, IL-6, IL-10, and TNF-a) and Lymphopenia are associated with the severity of COVID-19 disease. The use of anti-inflammatory agents such as corticosteroids (CS) or Tosilizumab (TCZ) has been suggested for the treatment of advanced stage of COVID-19 and reduction of mechanical ventilators and mortality. The aim of this meta-analysis is to determine the role of combination therapy with Tocilizumab and steroid in COVID-19 patient. Material and methodsRelevant studies were found using online international databases and suitable studies were selected and assessed by two independent researchers. The quality of all papers were determined by a checklist. Heterogeneity assay among the primary studies was evaluated by Cochran's Q test and I2 index. The statistical analyses were done using Stata ver. 14 package (StataCorp, College Station, TX, USA) software. Publication bias was estimated through the Egger's test and the impact of each study on the overall estimate was assessed by sensitivity analysis.Result 6 studies were entered into this meta-analysis. The results of these studies showed that the risk of death for COVID-19 patients treated with the combination of corticosteroids and Tocilizumab compared to Tocilizumab or [C1] control group was 0.74 (95% CI: 0.36-1.50) and 0.48(95% CI: 0.31-0.74) respectively. ConclusionThis meta-analysis showed that the risk of death in COVID-19 patients who treated with Corticosteroids and Tocilizumab was lower than Tocilizumab and control group (26% and 52% respectively).

scholarly journals ROLE OF REGRET AVERSION AND LOSS AVERSION EMOTIONAL BIASES IN DETERMINING INDIVIDUAL INVESTORS’ TRADING FREQUENCY: MODERATING EFFECTS OF RISK PERCEPTION

2021 ◽  
Vol 9 (3) ◽  
pp. 1373-1386
Author(s):  
Sayed Ibtasam Shafqat ◽  
Imran Riaz Malik
Keyword(s):  
Risk Perception ◽  
Loss Aversion ◽  
Positive Impact ◽  
Primary Data ◽  
Individual Investors ◽  
Trading Frequency ◽  
Regret Aversion ◽  
The Impact ◽  
The Relationship

Purpose: This study aims to investigate the moderating effect of risk perception on the relationship among emotional biases (i.e., regret aversion and loss aversion) and the trading frequency of individual investors in the context of the Pakistan Stock Exchange (PSX). Approach / Methodology: This study is conducted under the philosophical assumptions of the positivist paradigm and the approach is deductive. The convenience sampling technique is used for sample selection of registered individual investors on the database of PSX. This led the study towards designing a cross-sectional study. Furthermore, 384 questionnaires are used for the collection of primary data from a population of 0.22 million registered PSX individual investors. The direction and degree of relationship among variables of concern are analyzed by the multiple linear regression techniques. The structural Equation Modelling (SEM) technique is used for authentication of moderation results. Findings: The results depict that regret aversion and loss aversion have statistically significant and negative impacts on individual investors’ trading frequency. Whereas, risk perception has an insignificant & positive impact on individual investors’ trading frequency. Moreover, risk perception is found to moderate the relationship between these two emotional behavioral biases. Originality/Value: This current study is a pioneer in developing links between individual investors’ trading frequency, loss aversion, regret aversion, and risk perception. The article also contributes to the literature of behavioral finance, specifically while understanding the role of emotional biases in investment strategies. So, this article engenders the reader's thoughtfulness to find plausible explanations in minimizing the impact of emotional biases in trading frequency and decision-making of individual investors. Implications: This study implies that emotional biases and risk perception cause and moderate the magnitude of the trading frequency of individual investors. The regulatory bodies such as the Securities and Exchange Commission of Pakistan (SECP) and PSX can launch training programs for individual investors to train them in coping up with such emotional biases and risk perception. This might result in the enhancement of the market capitalization of the stock market.

An evaluation of serum Otolin-1 & Vitamin-D in benign paroxysmal positional vertigo

2021 ◽  
pp. 1-8
Author(s):  
Harsha Yadav ◽  
DVK Irugu ◽  
Lakshmy Ramakrishanan ◽  
Archana Singh ◽  
Ransi Abraham ◽  
...  
Keyword(s):  
Vitamin D ◽  
Inner Ear ◽  
Test Group ◽  
Control Group ◽  
Vitamin D Levels ◽  
Head Roll ◽  
And Control ◽  
The Relationship ◽  
Paroxysmal Positional Vertigo

BACKGROUND: Serum otolin-1 is an inner ear protein exclusively expressed in otoconia and cells of vestibule and cochlea. Serum otolin-1 is found to be quantifiable in patients with BPPV. Low Vitamin-D is associated with pathogenesis of BPPV. Since otoconia degeneration contributes to BPPV, lack of Vitamin-D may impact otoconia structure and integrity. OBJECTIVE: We aimed at studying the s.otolin-1 as biomarker and significance of vit-D in BPPV. MATERIAL AND METHOD: 23 patients in test and control groups respectively were chosen within the age of 20 to 65 years. All the patients were diagnosed using Dix Hallpike menouver and head roll test, patients were treated with appropriate Canal Reposition Menouver (CRM). RESULTS: Serum Otolin-1 levels among the test ranged from 366 to 882 pg/mL with mean of 585.17 pg/mL whereas in control group ranged from 223 to 462 pg/mL with mean of 335.26 pg/mL. Mean Vitamin-D levels among the test group was 22.67 ng/mL (Range = 6.3–68.4) and that of control 15.43 pg/mL (Range = 5.4–27.7) respectively. The relationship between the serum Otolin-1 and Vitamin-D was not statistically significant. CONCLUSION: Otolin-1 levels is increased in BPPV patients and is sensitive in BPPV, specificity needs to be validated. Role of vitamin-D with respect to inner ear proteins needs further investigation.

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