scholarly journals The Relationship of Body Mass Index with Disease Activity in Ankylosing Spondylitis

2020 ◽  
Vol 3 (2) ◽  
pp. 71-85
Author(s):  
Raouf Merza ◽  
Kurdistan Ali ◽  
Dlair Mohamad ◽  
Sundus Wahhab

Find out the relationship between body mass index (BMI) and W.C with disease activity scorein AS patients and its association with clinical characteristics of AS. One hundred and five patients (75 male and 30 female) who visited rheumatology and medical rehabilitation centerin Sulaimani city were recorded in this cross-sectional study. Disease activity was measured by ASDAS-ESR in the hand-held calculator.BMI was calculated and waist circumference(W.C.) was measured and both were evaluated with disease activity score and disease characteristics in those with normal BMI and W.C and those with abnormal BMI and W.C.Data of one hundred and five patients were involved in this study with a mean age of 37±9.5 years with the predominance of male gender (71.4%). The mean BMI of the patients was27.2±4.6 kg/m², 28.6% of them were obese and 35.2% of them were overweight. Patients who were overweight, obese and increased W.C had significantly higher disease activity scoresand older compared to those who had normal BMI and W.C(p value<0.05).There was no statistically significant difference between the two groups in terms of peripheral arthritis,disease duration, clinical characteristics of AS, and gender (P value>0.05). Overweight, obesity and increased W.C are common among AS patients and significantly related to disease activity score and age, but not with disease characteristics and gender

RMD Open ◽  
2016 ◽  
Vol 2 (1) ◽  
pp. e000283 ◽  
Author(s):  
Roxana Rubio Vargas ◽  
Rosaline van den Berg ◽  
Miranda van Lunteren ◽  
Zineb Ez-Zaitouni ◽  
Pauline A C Bakker ◽  
...  

2012 ◽  
Vol 39 (12) ◽  
pp. 2310-2314 ◽  
Author(s):  
LAURA DURCAN ◽  
FIONA WILSON ◽  
RICHARD CONWAY ◽  
GAYE CUNNANE ◽  
FINBAR D. O’SHEA

Objective.Increased body mass index (BMI) in patients with ankylosing spondylitis (AS) is associated with a greater burden of symptoms and poor perceptions of the benefits of exercise. In AS, the effect of obesity on disease characteristics and exercise perceptions is unknown. We evaluated the prevalence of obesity in AS, to assess the attitudes of patients toward exercise and to evaluate the effect of obesity on symptoms and disease activity.Methods.Demographic data and disease characteristics were collected from 46 patients with AS. Disease activity, symptomatology, and functional disability were examined using standard AS questionnaires. BMI was calculated. Comorbidity was analyzed using the Charlson Comorbidity Index. Patients’ attitudes toward exercise were assessed using the Exercise Benefits and Barriers Scale (EBBS). We compared the disease characteristics, perceptions regarding exercise, and functional limitations in those who were overweight to those who had a normal BMI.Results.The mean BMI in the group was 27.4; 67.5% of subjects were overweight or obese. There was a statistically significant difference between those who were overweight and those with a normal BMI regarding their perceptions of exercise (EBBS 124.7 vs 136.6, respectively), functional limitation (Bath AS Functional Index 4.7 vs 2.5, Health Assessment Questionnaire 0.88 vs 0.26), and disease activity (Bath AS Disease Activity Index 4.8 vs 2.9). There was no difference between the groups in terms of their comorbid conditions or other demographic variables.Conclusion.The majority of patients in this AS cohort were overweight. They had a greater burden of symptoms, worse perceptions regarding the benefits of exercise, and enhanced awareness of their barriers to exercising. This is of particular concern in a disease where exercise plays a crucial role.


2010 ◽  
Vol 95 (7) ◽  
pp. 3517-3521 ◽  
Author(s):  
Katherine G. Meilleur ◽  
Ayo Doumatey ◽  
Hanxia Huang ◽  
Bashira Charles ◽  
Guanjie Chen ◽  
...  

Context: Adiponectin, a hormone secreted by adipose tissue, has both metabolic and antiinflammatory properties. Although multiple studies have described the relationship between adiponectin and obesity in several human populations, no large studies have evaluated this relationship in Africans. Objective: We investigated the relationship between adiponectin and measures of obesity, serum lipids, and insulin resistance in a large African cohort. Design: Participants are from the Africa America Diabetes Mellitus (AADM) Study, a case-control study of genetic and other risk factors associated with development of type 2 diabetes in Africans. Setting: Patients were recruited from five academic medical centers in Nigeria and Ghana (Accra and Kumasi in Ghana and Enugu, Ibadan, and Lagos in Nigeria) over 10 yr. Main Outcome Measures: Circulating adiponectin levels were measured in 690 nondiabetic controls using an ELISA. The correlation between log-transformed circulating adiponectin levels and age, gender, measures of obesity (body mass index, waist circumference, and percent fat mass), and serum lipid levels was assessed. Linear regression was used to explore the association between adiponectin levels and measures of obesity, lipids, and insulin resistance as measured by homeostasis model assessment. Results: Significant negative associations were observed between log-adiponectin levels and measures of obesity after adjusting for age and gender. Similarly, log-adiponectin levels were significantly negatively associated with serum triglycerides and insulin resistance but positively associated with high-density lipoprotein-cholesterol and total cholesterol after adjusting for age, gender, and body mass index. Conclusions: Circulating adiponectin is significantly associated with measures of obesity, serum lipids, and insulin resistance in this study of West African populations.


2021 ◽  
Vol 1 (2) ◽  
pp. 52-58
Author(s):  
Devi ◽  
Bambang S ◽  
Sumedi W

Introduction: Dietary factors or eating patterns can cause patients to experience anorexia so that it affects the body mass index measured by CKD patients (Susetyowati, 2014). Therefore, it is important to understand the research when studying the relationship between the diet of CKD patients and the body mass index of patients undergoing hemodialysis at the Dik Pusdikkes Hospital in 2021. Objective: This study aims to determine how big the influence of the relationship between the diet of CKD patients and the body mass index of patients undergoing hemodialysis to improve the quality of life of CKD patients. Method: The type of research used is quantitative research with a correlational design to determine whether there is a relationship between variables using experimental research. The population in this study that became the study population were all hemodialysis patients at the AD Pusdikkes Hospital. The sampling technique used was total sampling. The research instrument used is a questionnaire. The questionnaire is not standardized so that validity and reliability tests are carried out. In this study, the analysis used the chi-square test. Results: the results of the chi-square test showed that the p-value (0.028) <0.05 then Ha was accepted or there was a relationship between the diet of CKD patients and the patient's body mass index. Conclusion: Based on the results of the analysis of the relationship between the evaluation of hemodialysis patients at RS Dik Pusdikkes Kodiklat AD, 9 respondents had a poor diet with a body mass index in the lean category of 6 people (66.7%) and the normal category of 3 people (33.3%). And 11 respondents have a good diet relationship with body mass index in the thin category of 2 people (40.0%) and the normal category of 12 people (60%).


2021 ◽  
Vol 1 (1) ◽  
pp. 103-114
Author(s):  
Rilyani Rilyani ◽  
Lidya Aryanti ◽  
Calvyn Reza Trisnantyas

ABSTRACT: EMPLOYMENT RELATIONSHIP AND WORKING SCHEDULE WITH BODY MASS INDEX IN YOSODADI PUSKESMAS WORKING AREA METRO CITY Introduction: The coverage of children under five in Lampung Province in 2019 was 79%, and this figure was above the target (76.18%). This figure illustrates that participation from the community to come to posyandu is still quite good in Lampung Province, while for Metro City the percentage of data is weighted at 78.8%. Data obtained through the Metro City Health Office in 2020 at the Yosodadi Health Center obtained as many as 656 toddlers aged 1-5 years who were weighingObjective: To find out the relationship between work and work schedule with the body mass index of toddlers aged 1-5 years.Methods: This type of research is quantitative. The design in this study uses an analytical survey design with a cross-sectional approach. The population is mothers and children aged 3-5 years, which is then calculated using the Slovin formula to obtain 197 children. Sampling technique purposive sampling Analysis of univariate and bivariate data using the chi-square test.Results: working mothers as many as 107 respondents (54.3%)., standard work schedule is 8 hours per day as many as 109 respondents (55.3%), BMI is not ideal, namely < 18.5 and > 22.9 as many as 103 respondents ( 52.3%. The results of statistical tests using the chi-square test obtained p-value = 0.000 (<α0.05), p-value = 0.085 (>α0.05).Conclusion: The results of statistical tests using the chi-square test obtained p-value = 0.000 (<α0.05) which means the relationship between mother's work and body mass index of toddlers aged 3-5. The p-value = 0.085 (>α0.05) means that there is no relationship between the mother's work schedule and the body mass index of children aged 3-5 years. It is recommended that parents who have toddlers with underweight and obese nutritional status should pay more attention to parenting patterns Keywords            :  Mother's Work Work Schedule, Toddler Body Mass Index  INTISARI: HUBUNGAN PEKERJAAN DAN JADWAL KERJA DENGAN INDEKS MASSA TUBUH BALITA DI WILAYAH KERJA PUSKESMAS YOSODADI KOTA METRO   Pendahuluan: Cakupan balita ditimbang di Provinsi lampung tahun 2019 sebesar 79 %, dimana angka ini diatas target (76,18%). Angka ini menggambarkan bahwa partisipasi dari masyarakat untuk datang ke posyandu masih cukup baik di Provinsi Lampung, sedangkan untuk Kota Metro persentase data ditimbang sebesar 78,8%. Data yang diperoleh melalui Dinkes Kota Metro tahun 2020 di Puskesmas Yosodadi didapat sebanyak 656 balita usia 1-5 tahun yang melakukan penimbangan berat badanTujuan: Diketahui hubungan pekerjaan dan jadwal kerja dengan  indeks massa tubuh balita usia 1-5 tahun.Metode: Jenis penelitian kuantitatif, Rancangan dalam penelitian ini menggunakan desain Survei Analitik dengan pendekatan cross sectional. Populasi adalah  ibu dan anak usia 3-5 tahun, yang kemudian dilakukan perhitungan sampel dengan rumus slovin didapat sebanyak 197 anak. Teknik sampling purposive sampling Analisa data univariat dan bivariat  menggunakan uji chi square.Hasil : ibu bekerja sebanyak 107 responden (54,3%)., jadwal kerja standar yaitu 8 jam per hari sebanyak 109 responden (55,3%), IMT tidak ideal yaitu < 18,5 dan > 22,9 sebanyak 103 responden (52,3%). Hasil uji statistik menggunakan uji chi square didapat nilai p-value = 0.000 (<α0.05), nilai p-value = 0.085 (>α0.05).Kesimpulan : Hasil uji statistik menggunakan uji chi square didapat nilai p-value = 0.000 (<α0.05) yang artinya ada hubungan pekerjaan ibu dengan  indeks massa tubuh balita usia 3-5. Nilai p-value = 0.085 (>α0.05) yang artinya tidak ada hubungan jadwal kerja ibu dengan  indeks massa tubuh balita usia 3-5 tahun. Disarankan kepada orang tua yang memiliki balita dengan status gizi kurus dan gemuk, harus lebih memperhatikan lagi mengenai pola asuh anak           Kata Kunci      : Pekerjaan Ibu Jadwal Kerja, Indeks Masa Tubuh Balita 


2021 ◽  
Author(s):  
Harpreet Singh ◽  
Somdatta Giri ◽  
Hemant Kumar ◽  
Pratibha Yonzone ◽  
Mahima Khatkar

Abstract Objective To assess the utility of Patient Based Disease Activity Score 2 (PDAS 2) in assessing the disease activity in Rheumatoid arthritis (RA). Methods A prospective cohort study was conducted on 80 patients of RA. The demographic and clinical characteristics of the patients were recorded. They were assessed for disease activity using “Disease Activity Score 28” (DAS 28), “Clinical Disease Activity Index” (CDAI) and PDAS 2 score at baseline (M0), at 2 months (M2) and at 4 months(M4) while they were on treatment. Data was analyzed for correlation of PDAS-2 with other scores and internal reliability. P < 0.05 was considered for statistical significance. Results The mean age was 40.13\(\pm\) 11.74 years with 70 females and 10 males. There was significant reduction in DAS28, CDAI and PDAS 2 score over 4 month follow up (all scores’ p values < 0.001). Internal reliability (as assessed by Cronbach’s Alpha) of PDAS 2 was 0.578. PDAS 2 showed significant correlation with DAS28 at M0, M2 and M4 (r = 0.792, 0.757 and 0.669 respectively, p value < 0.001) and CDAI (r = 0.861, 0.832 and 0.695 respectively, p value < 0.001). Overall there was a significant agreement between DAS 28 and PDAS 2 (K = 0.788,p < 0.001) and between CDAI and PDAS 2 (K = 0.766,p < 0.001). Conclusion PDAS-2 score can be routinely used in the clinical practice owing to its correlation with DAS-28/CDAI and because of the advantage that it assessed the patients’ daily living activities.


2021 ◽  
Vol 10 (4) ◽  
pp. 328-334
Author(s):  
Anggrita Salsabila Ramadhia ◽  
Harna Harna ◽  
Mertien Sa'pang ◽  
Nadiyah Nadiyah

Background: Adequate micronutrients intake is essential to ensure the immune function. Certain populations may have insufficient intake of micronutrients, and in situations that increase the demand for example infections, stress, and pollution that decrease the body's stores of micronutrients, putting them at risk of deficiency and may impair immunity. Several researchs related to micronutrient intake, nutritional status, sleep duration are still contradictory results in showing the relationship with immunity.Objectives: To determine the relationship between micronutrient intake, sleep duration, body mass index and the immune status of Balitbang Hukum dan HAM employees.Methods: This type of research is an observational study with a cross sectional approach. The sampling technique used was simple random sampling technique. The samples taken were 47 people.Results: Median intake of micronutrient vitamin A 1024.5 mcg, vitamin C 208.3 mg, vitamin D 1.4 mcg, vitamin E 3.5 mg, iron 5.1 mg, zinc 4.2 mg. Meanwhile, the median sleep duration was 6 hours and the median body mass index was 22.2 kg / m2. The intake of micronutrients with immune status has a p value> 0.05. Sleep duration with immune status has a p value <0.05 with a negative relationship direction. Body mass index with immune status has a p value> 0.05.Conclusion: There is no relationship between micronutrient intake and body mass index with immune status, meanwhile there is a relationship between sleep duration and immune status of Balitbang Hukum dan HAM employees.Keywords : Micronutrient intake; Sleep duration; Body mass index; Immune status


2021 ◽  
Vol 2 (1) ◽  
pp. 27-33
Author(s):  
Slamet

Obesity occurs due to excessive fat deposits in the body, one of which is a poor diet. The relationship between overweight and chronic kidney disease (CKD) is mediated through several mechanisms of adiponectin, leptin, and resistin, the development of inflammation, oxidative stress, abnormal lipid metabolism, and activation of the renin-angiotensin-aldosterone system. The purpose of this study was to determine the relationship between body mass index and estimated glomerular filtration rate in overweight students at the Health Analyst Department of Pontianak Health Polytechnic. The research design used was cross-sectional. This research was conducted on May 14-18, 2018. The population is a student health analyst. With the criteria for students from the 2015 and 2016 batches who are still active, BMI 23-29.9 Kg/m² and aged 18 to 22 years, totaling 37 respondents. The sampling technique used is total sampling. Performed include measurements of BMI, serum creatinine Jaffe method, fixed time and ELFG Cokroft-Gault formula. The results obtained using the Kendall's tau test showed that the p value (0.906) was greater than (0.05) meaning that there was no relationship between body mass index and estimated glomerular filtration rate in overweight students at the Health Analyst Department of Pontianak Health Polytechnic.


Nutrients ◽  
2020 ◽  
Vol 12 (7) ◽  
pp. 1951
Author(s):  
Yi-Syuan Lin ◽  
Yu-Tang Tung ◽  
Yu-Chun Yen ◽  
Yi-Wen Chien

Perceived stress is the degree of stress experienced by an individual in the face of a stressor. Studies have shown that stress affects emotions, leads to behavioral changes, and is likely to trigger physical illnesses. According to the World Health Organization (WHO), stress is classified as a health epidemic of the 21st century; in the meantime, the percentage of adults being overweight and with obesity has continued to grow after reaching 38.9% in 2016. Hence, it is unclear whether perceived stress has become a factor affecting progressive obesity and whether food addiction (FA) is an intermediate factor. The purposes of this study were to (1) investigate the FA prevalence among young adults in Taiwan, (2) understand correlations among perceived stress, FA, and the body mass index (BMI), and (3) determine the potential mediating effect of FA due to perceived stress on BMI. The study was conducted through an online questionnaire, composed of a basic data form, the Perceived Stress Scale (PSS), and the Yale Food Addiction Scale (YFAS). We received 1994 responses and analyzed 1780 valid samples. Results showed that 231 participants met the FA criteria, accounting for 12.98%. Perceived stress was positively correlated with BMI (95% confidence interval (CI) 0.013~0.088, p-value 7.8 × 10−3), and perceived stress was positively associated to FA (95% CI 1.099~1.154, p-value < 10−4), which was also positively correlated with BMI (95% CI 0.705~2.176, p-value 10−4). FA significantly mediated the relationship between PSS and BMI with an indirect effect size of 25.18% and 25.48% in the group that scored 31~40 on the PSS. The study concluded that among people seeking weight loss, proper stress management and screening for FA in order to apply related therapies may be an effective method for weight management.


2021 ◽  
Vol 71 (6) ◽  
pp. 1916-19
Author(s):  
Syed Haider Tirmizi ◽  
Amer Fakhr ◽  
Ahsan Amer ◽  
Kaswar Sajjad ◽  
Khurram Haq Nawaz ◽  
...  

Objective: To determine the efficacy of Methotrexate versus Leflunomide versus combination of both among patients managed at Pak Emirates Military Hospital with active rheumatoid arthritis. Study Design: Prospective comparative study. Place and Duration of Study: Rheumatology/General Medicine Department, Pak Emirates Military Hospital Rawalpindi, from May 2019 to June 2020. Methodology: Patient of active rheumatoid arthritis who fulfilled American college of rheumatology criteria of 1997 were included in the study. They were randomly divided into three groups with group A receiving Methotrexate, group B receiving Leflunomide while group C received the combination of both Methotrexate and Leflunomide. Disease activity was assessed by using the Disease Activity Score-28 in all the three groups after three months of treatment. Results: Mean age of the study participants was 36.919 ± 6.85 years. One hundred and fifty (83.3%) patients were female while 30 (16.7%) were male. Out of 160 (88.9%) patients achieved remission according to Disease Activity Score-28 score at the end of three months while 20 (11.1%) did not achieve remission. Pearson chi-square test revealed that none of the factors studied including the treatment option had any statistically significant relationship with presence of remission among the target population (p-value 0.386, 0.815, 0.194 and 0.145 for age, gender, duration of symptoms and type of treatment respectively). Conclusion: Remission rate among the rheumatoid arthritis patients in response to treatment was overall good in the study. In terms of efficacy for symptoms of rheumatoid arthritis and achieving remission, after three months of treatment all the three options..................


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