scholarly journals Relationship of Mutation of Kodon S 315 T katG Mycobaterium Tuberculosis Gene with Multidrug Resistance Tuberculosis in South Sumatera

2020 ◽  
Vol 6 (1) ◽  
pp. 1-8
Author(s):  
Diah Syafriani ◽  
Rouly Pola Pasaribu ◽  
Zen Ahmad
Keyword(s):  
Cross Sectional Study ◽  
Control Group ◽  
Case Group ◽  
Clinical Microbiology Laboratory ◽  
Katg Gene ◽  
Cross Sectional ◽  
Study Approach ◽  
Pcr Rflp ◽  
Mdr Tb ◽  
Relationship Of

MDR TB is a condition of M. tuberculosis that is resistant to isoniazid and rifampicin. This occurs because of certain genomic mutations in certain Mtb specific genes. Some of the genes that play a role in the INH mutation are the katG gene, the inhA gene, the ahpC gene, the ndh gene and the kasA gene. The most frequent mutation gene is the katG gene, around 50-80%, and the most mutations (64%) are found in the S 315T codon. The aim was to determine the relationship of S315T genotype in the M. tuberculosis katG gene with the incidence of Mtb resistance in MDR TB patients in South Sumatra. This type of research is an observational cross sectional study approach, conducted in Palembang RSMH in collaboration with the Clinical Microbiology Laboratory of FK UNSRI Palembang from January - July 2019. The sample of the case group (MDR TB) was 50 people while the control group (TB SO) was 21 people. Each group was tested for S315T genotype katG M. tuberculosis gene using the PCR-RFLP method with the Mspl enzyme. Visualization of the katG gene in codon 315 in this study was only found in 40 samples, 26 samples in the case group (MDR TB) and 14 samples in the control group (TB SO). Results Genetic frequency distribution in the case group (MDR TB) was 65.38% wildtype and 34.62% mutant, whereas in the control group (TBSO) it was 92.86% wildtype and 7.14% mutant. The 315 coded KatG gene mutation in this study was not related to the incidence of MDR TB, with p = 0.07, an odds ratio of 6.8 (0.77 - 61.40, 95% CI). The conclusions of this study found 315G katG M. tuberculosis codon mutation mutations of 34.62% but not significantly related to the incidence of MDR TB in South Sumatra.

scholarly journals Hubungan Dukungan Keluarga dengan Tingkat Harga Diri pada Penderita Stroke di Rumah Sakit Umum Royal Prima Medan

2020 ◽  
Vol 4 (2) ◽  
pp. 66
Author(s):  
Yusmawarnita Zai ◽  
Kandrinus Bu’ulolo ◽  
Novy Fajariani ◽  
Yasozatulo Hulu ◽  
Ruslan Efendi Gulo ◽  
...  
Keyword(s):  
Family Support ◽  
Self Esteem ◽  
Cross Sectional Study ◽  
P Value ◽  
Stroke Patients ◽  
Chi Square ◽  
Cross Sectional ◽  
Study Approach ◽  
Chi Square Test ◽  
Relationship Of

Stroke is a condition where a part of the brain is suddenly disturbed which is caused by a lack of blood supply, which causes an inhibition of metabolic processes. As a result of a stroke affects the psychological function of the patient, so the patient feels his level of self-esteem decreases or is low. The role and support of families play an important role in the rehabilitation process to provide health services for stroke patients. The aim is to find out the relationship of family support with the level of self esteem (self-esteem) in stroke patients at the Royal Prima Medan Hospital in 2019. The design used a "cross sectional study" approach with a population of 2,690 people. Samples were stroke patients at RSU Royal Prima medan, as many as 25 respondents using accidental sampling techniques and questionnaires as research instruments. The test used is the chi-square test. The results of the study Based on the chi-square test found p value (<0.05) statistically shows that there is a relationship between family support and the level of self esteem (self-esteem) in stroke patients specifically there is a relationship between informational support (p-value = 0.009), assessment support (p-value = 0.003), Instrumental support is obtained (p-value = 0.009), Emotional support (p-value = 0.004) with the level of self esteem (self-esteem) in stroke patients. This research shows that good family support will positively impact the level of self esteem (self-esteem) in stroke patients.

scholarly journals Development of cleft children’s permanent canines

2019 ◽  
Vol 67 ◽  
Author(s):  
Manoel Itaguacy Leite NOVAIS JUNIOR ◽  
Manuella Santos Carneiro ALMEIDA ◽  
Camila Helena Machado da COSTA ◽  
Tassia Cristina de Almeida Pinto SARMENTO ◽  
Luis Ferreira de SOUSA FILHO ◽  
...  
Keyword(s):  
Cleft Lip ◽  
Cleft Lip And Palate ◽  
Tooth Development ◽  
Cross Sectional Study ◽  
Control Group ◽  
Case Group ◽  
Age Difference ◽  
Cross Sectional ◽  
Panoramic Radiographs ◽  
Significant Difference

ABSTRACT Objective: Evaluating the development of the permanent cuspids in children from Paraíba with cleft lip and palate applying the Nolla and the Demirjian methods. Methods: A cross-sectional study using an inductive approach and applying a comparative statistical procedure and direct documentation research technique. The universe of the study consisted of children assisted at the orthodontic practice of the Brazilian Association of Dentistry - Paraíba Section. The sample comprised 72 pairs of panoramic radiographs of children with and without cleft lip and palate from the same gender and, age difference of up to 30 days, ranging from 5 to 13 years of age. The study has evaluated the development of 576 cuspids. The images were evaluated by three duly calibrated examiners concomitantly, and the calcification stages were determined by a consensus. The stages of the cuspids calcification were evaluated in the panoramic radiographs according to Nolla and Demirjian classifications. Results: The average of the calcification stage of teeth was correspondingly higher in the control group than in the case group, showing a development delay of the cuspid teeth in the cleft lip and palate patients. The lower cuspids were significantly more developed than the upper cuspids (p <0.001). There were no significant differences between the sides. There was early tooth development in females but without significant difference. Conclusion: It was possible to note that patients with cleft lip and palate presented a delay in the development of the permanent cuspids when compared to non-cleft lip and palate patients, thus, reinforcing the importance of the individualization of the orthodontic planning.

scholarly journals Three-dimensional volumetric evaluation of the different mandibular segments using CBCT in patients affected by juvenile idiopathic arthritis: a cross-sectional study

2021 ◽  
Vol 22 (1) ◽  
Author(s):  
Davide Cavagnetto ◽  
Andrea Abate ◽  
Alberto Caprioglio ◽  
Paolo Cressoni ◽  
Cinzia Maspero
Keyword(s):  
Juvenile Idiopathic Arthritis ◽  
Three Dimensional ◽  
Pairwise Comparison ◽  
Cross Sectional Study ◽  
Control Group ◽  
Case Group ◽  
Unaffected Side ◽  
Cross Sectional ◽  
Affected Side ◽  
Significant Difference

Abstract Background There is currently no information on how different mandibular segments are affected by juvenile idiopathic arthritis. The aim of this paper is to assess volumetric differences of different mandibular segments in subjects with unilateral and bilateral JIA and to compare them with non-JIA control volumes. Materials and methods Forty subjects with unilateral TMJ involvement and 48 with bilateral TMJ involvement were selected for the case group and 45 subjects with no known rheumatic comorbidities for the control group. The mandible of each subject was divided according to a validated method into different paired volumes (hemimandible, condyle, ramus and hemibody). Results The ANOVA test revealed a statistically significant difference in all the groups for condylar and ramus volumes, and the pairwise comparison evidenced a statistically significant higher condylar and ramus volume in the control group (1444.47 mm3; 5715.44 mm3) than in the affected side in the unilateral JIA group (929.46 mm3; 4776.31 mm3) and the bilateral JIA group (1068.54 mm3; 5715.44 mm3). Moreover, there was also a higher condylar volume in the unaffected side in the unilateral JIA group (1419.39 mm3; 5566.24 mm3) than in the bilateral JIA group and the affected side in the unilateral JIA group. Conclusions The affected side of unilateral JIA patients showed statistically significant lower volumes in the hemimandible, in the condyle and in the ramus. The largest total mandibular volume was observed in the control group, followed by the unilateral JIA group and, lastly, by the bilateral JIA group.

scholarly journals Relationship of circulating total bilirubin, UDP-glucuronosyltransferases 1A1 and the development of non-alcoholic fatty liver disease: a cross-sectional study

2022 ◽  
Vol 22 (1) ◽  
Author(s):  
Xuefeng Ma ◽  
Xu Zheng ◽  
Shousheng Liu ◽  
Likun Zhuang ◽  
Mengke Wang ◽  
...  
Keyword(s):  
Total Bilirubin ◽  
Cross Sectional Study ◽  
Liver Fat ◽  
Control Group ◽  
Chinese Han ◽  
Cross Sectional ◽  
Alcoholic Fatty Liver ◽  
Significant Difference ◽  
Fat Fraction ◽  
Relationship Of

Abstract Background This study aimed to investigate the correlation of circulating total bilirubin (TB) and UGT1A1 with NAFLD in Chinese Han population. Methods 172 adults were enrolled from the Qingdao Municipal Hospital from May 2019 to October 2020. All individuals were examined with MRI-PDFF and divided into no steatosis, mild steatosis, moderate steatosis, and severe steatosis groups according to the MRI-PDFF values. The biochemical indexes and UGT1A1 were measured. Results There was no significant difference of circulating TB and UGT1A1 levels between NAFLD group and controls. In the moderate steatosis and severe steatosis groups, the circulating TB levels were higher than that in control group (all P < 0.05). In addition, circulating TB levels were weak positively associated with liver fat fraction in NAFLD patients (ρ = 0.205, P = 0.001). There was no significant correlation between circulating UGT1A1 levels with liver fat fraction in patients with NAFLD (ρ = 0.080, P = 0.179), but positively correlation was found in patients with severe steatosis (ρ = 0.305, P = 0.026). Conclusions The circulating TB levels were significant high in patients with moderate and severe steatosis. Circulating TB levels were weakly associated with liver fat fraction in patients with NAFLD, and the circulating UGT1A1 levels were positively correlated with liver fat fraction in NAFLD patients with severe steatosis. Trial registration: ChiCTR, ChiCTR1900022744. Registered 24 April 2019 – Retrospectively registered, http://www.chictr.org.cn/edit.aspx?pid=38304&htm=4.

Correlation between gastrointestinal symptoms and adherence to traditional Persian medicine dietary recommendations in patients with vitiligo; a cross-sectional study

2021 ◽  
Vol 0 (0) ◽  
Author(s):  
Amir Mohammad Jaladat ◽  
Ehsan Amiri-Ardekani ◽  
Pariya Sadat Ramezani ◽  
Mohadese Boroughani ◽  
Morteza Emami Alorizi ◽  
...  
Keyword(s):  
Gastrointestinal Symptoms ◽  
Cross Sectional Study ◽  
Control Group ◽  
Case Group ◽  
Sectional Study ◽  
Dietary Recommendations ◽  
Cross Sectional ◽  
Persian Medicine ◽  
Traditional Persian Medicine

Abstract Objectives Vitiligo is a chronic disease associated with the depigmentation of regions of the skin secondary to structural or functional damage to melanocytes. This damage results from interactions between the immune system and oxidative stress. In traditional Persian medicine (TPM), the concept of ‘Barass’ or ‘Pissi’ encompasses a group of skin diseases including vitiligo, for which there has been an emphasis on the preventive and therapeutic role of dietary modifications. Methods In this cross-sectional study, 200 vitiligo patients and 200 controls were enrolled with a random sampling method. The participants included patients with vitiligo referred to the Dermatology Clinic of Shahid Faghihi Hospital (Shiraz, Iran), with the control group being comprised individuals who referred to this clinic for cosmetic purposes. Questionnaires comparing the severity of gastrointestinal symptoms and the rate of adherence to TPM dietary recommendations were filled by all participants. Data were analyzed using SPSS version 24.0. Results The case group was significantly less adherent to TPM recommendations than the control group (8.25 ± 27.16 vs. 31.8 ± 10.47; p<0.001). However, there was no significant difference between both groups in the Gastrointestinal Symptom Rating Scale (GSRS) scores (14.09 ± 14.84 vs. 12.62 ± 11.71; p = 0.105). In the case group, the level of adherence to the recommendations of TPM was significantly lower among patients with lower education levels (R=−0.194; p=0.017). Furthermore, there was a significant negative relationship between the length of the disease and adherence to TPM dietary recommendations (R=−0.247; p=0.002). Conclusions In this study, the level of adherence to TPM recommendations was significantly lower among patients with vitiligo than the control group. Hence, further studies are suggested to identify the probable role of dietary habits in the pathogenesis of vitiligo.

scholarly journals Association of Serum Zinc Level with Febrile Seizures in Children

2021 ◽  
pp. 200-203
Author(s):  
Maryum Naveed ◽  
Rimsha Mohsin ◽  
Palwasha Khan
Keyword(s):  
Febrile Seizure ◽  
Serum Zinc ◽  
Febrile Convulsion ◽  
Febrile Seizures ◽  
Cross Sectional Study ◽  
Zinc Level ◽  
Control Group ◽  
Case Group ◽  
Serum Zinc Level ◽  
Cross Sectional

Introduction: Febrile seizure (FS), previously known as febrile convulsion, is the most common seizure in children. FS usually occurs between six months and five years of age. Aims and objectives: The main objective of the study is to find the association of serum zinc level with febrile seizures in children of Pakistan. Material and methods: This cross sectional study was conducted at Mayo Hospital, Lahore during June 2020 to January 2021. The data was collected from 164 patients of both genders. Results: The data was collected from 164 patients. In the case group, 46 children were male (53.3%), and 36 children (46.7%) were female. In the control group 44 children were male (43.3%) and 38 children were female (56.7%). The age of all participants was between one months and six years. Conclusion: It is concluded that low serum zinc levels are fairly un-sufficient to support the hypothesis that Zinc deficiency could not be a potential risk factor for febrile seizure in children.

scholarly journals The Relationship Of Rewarding With Work Motivation Of Honorary Nurses

2017 ◽  
Vol 1 (2) ◽  
pp. 6-15
Author(s):  
Nadia Alfira ◽  
Safruddin
Keyword(s):  
Work Motivation ◽  
Cross Sectional Study ◽  
External Pressure ◽  
P Value ◽  
Cross Sectional ◽  
Study Approach ◽  
Nursing Services ◽  
Relationship Of ◽  
The Relationship ◽  
Health Service System

Nursing as a science that continues to develop, both due to external pressure and because of internal pressure nursing. One of the problems faced by Indonesian nurses in the health service system is the low standard of reward which can have an impact on nurse performance. The purpose of this study was to determine the relationship of rewarding with work motivation of nurses in the Inpatient Room of H. Andi Sulthan Daeng Radja Hospital in Bulukumba Regency, with total sampling taking 48 respondents.This research is a quantitative study using an analytic observational design using a cross-sectional study approach. The results of bivariate fisher analysis showed that the value of the p-value was 0.028 p (<0.05). The value of 0.028 is below the alpha value (0.05), thus there is a relationship between giving rewards with work motivation of nurses.Then it was concluded that there was a relationship between rewarding and work motivation for honorary nurses in the inpatient room of H. Andi Sulthan Daeng Radja Hospital in Bulukumba Regency. Based on the results of the study it is expected to the Hospital to provide more appropriate rewards or awards to improve better nursing services.

scholarly journals Association Between Geographic Tongue and Personal Temperament Based on the Knowledge of Persian Medicine

2020 ◽  
Vol In Press (In Press) ◽  
Author(s):  
Sara Pourshahidi ◽  
Arash Mansourian ◽  
Maryam Habibzadeh ◽  
Mohammad Mahdi Parvizi ◽  
Majid Nimrouzi
Keyword(s):  
Significant Relationship ◽  
Basic Research ◽  
Cross Sectional Study ◽  
Unknown Etiology ◽  
Control Group ◽  
P Value ◽  
Case Group ◽  
Oral Diseases ◽  
Cross Sectional ◽  
Persian Medicine

Background: Geographic tongue (GT) is one of the benign inflammatory oral diseases with unknown etiology. Objectives: The present study aimed to find the correlation between temperament (mizaj) and GT lesions in the context of Persian medicine and conventional approach. Methods: In this cross-sectional study, 401 eligible participants were selected, 201 as the case group and 200 as the control group. After obtaining informed consent, the participants were asked to fill out a questionnaire. Then, the collected data were analyzed using SPSS, version 21. Results: Patients with GT were moderate regarding hot-cold temperament, and they had dry temperament. There was a statistically significant relationship between dry temperament and GT lesions (P value = 0.037). In the control group, people without GT lesion possessed average temperament either regarding hot-cold or wet-dry temperament. Moreover, there was a statistically significant relationship between hot-dry temperament and GT lesions (P value = 0.002). Conclusions: The results of our study showed a higher frequency of GT in dry temperament. The dominant pattern for people with GT in compound and simple temperament was hot-dry and dry, respectively. The second more frequent temperament was hot. Following temperament change, treatment of GT lesion or alleviation of its disturbing symptoms is an issue, which might be determined by conducting basic research and well-designed clinical trials in the future.

scholarly journals Relationship of Blood Glucose Level and Severity of Periodontitis in Patients attended the Outpatient Periodontics Clinic of College of Dentistry, King Khalid University, Saudi Arabia

2012 ◽  
Vol 9 (2) ◽  
pp. 7-11
Author(s):  
Md Zahid Hossain ◽  
Hammam I Fageeh ◽  
Fadul A Gader ◽  
M Yunis Saleem
Keyword(s):  
Saudi Arabia ◽  
Tolerance Test ◽  
Cross Sectional Study ◽  
Control Group ◽  
Oral Glucose ◽  
Kingdom Of Saudi Arabia ◽  
Cross Sectional ◽  
Relationship Of ◽  
Made In

Aims: A prospective cross-sectional study was performed involving   30 patients who attended the College of Dentistry outpatient Periodontics   clinic of King Khalid University, Abha, Kingdom of Saudi Arabia during the period of 12th March -12th May, 2011. Methods: Clinical data were recorded from the randomly selected 30 patients where periodontitis was indexed after Loe H: J Periodontol 38 (suppl):610, 1967 and modified from Russel AL: J Dent Res 35:350, 1956. Diabetic conditions were determined by 2 separate fasting plasma glucose (FPG) levels determinations [100~125 mg/dL at 8 hours fasting] and oral glucose tolerance test (OGTT) [140~199 mg/dL at 2 hours after 75-g glucose load]. Results: Among 30 patients, mean age 33}7 (range 18~54) years, males 70% and females 30% were divided into three groups: i) 10 periodontitis patients having diabetes mellitus (DM), ii) 10 non-diabetic periodontitis patients and iii) 10 patients were not suffering from periodontitis or DM as a control group. Results revealed that patients having diabetes had more moderate to severe forms of periodontitis 50% (p<0.05) including type 2 (80%) than type1 (20%) DM, (p<0.05). Similarly, 80% of the periodontitis patients were found suffering from moderate to severe forms of periodontitis (p<0.05) in uncontrolled group (20%) of DM patients. Conclusion: The present study proved a clear relationship with the patients having diabetes and periodontitis including severity of the diseases and glycemic control. Using these results, a greater effort can be made in providing periodontal as well as overall health to the population of at or around of Abha city of Saudi Arabia. DOI: http://dx.doi.org/10.3329/cdcj.v9i2.12313 City Dental College J. Volume-9, Number-2, July-2012

scholarly journals Semen Quality and Ferritin and Transferrin Seminal Levels

Folia Medica ◽  
2018 ◽  
Vol 60 (4) ◽  
pp. 632-636
Author(s):  
Gilmar Pereira Silva ◽  
Vítor Pereira Xavier Grangeiro ◽  
Fabiana Pirani Carneiro
Keyword(s):  
Semen Quality ◽  
Ferritin Level ◽  
Cross Sectional Study ◽  
Chronic Hemodialysis ◽  
Control Group ◽  
Case Group ◽  
Cross Sectional ◽  
Seminal Parameters ◽  
Seminal Parameter ◽  
And Control

Abstract Background: We proposed to investigate the possible relationship between seminal quality and ferritin and transferrin seminal levels in chronic hemodialysis (CH) patients. Materials and methods: This is a cross-sectional study in a group of 60 men (case) undergoing CH for more than 6 months, and a group of 30 healthy men (control), aged 18-60 years, without clinical or laboratory signs of infection/inflammation and eugonadic. A spermogram was performed by manual method and measured the ferritn and transferrin seminal levels. Results: The case and control groups were age-matched (49.47±5.56 versus 47.90±6.22, p = 0.229). Comparison between case and control group, the exception of seminal ferritin levels that were similar (p = 0.136), were significantly lower in the case group (p<0.001) for all constituents of the seminal parameter and seminal transferrin levels. Seminal ferritin does not appear to be associated with seminal parameters and seminal transferrin (p>0.05); but there was an association between seminal transferrin and seminal parameters (p<0.001). Conclusions: Our results suggest that seminal quality is related to seminal transferrin level and not with seminal ferritin level being useful in the initial evaluation of chronic hemodialysis patients with clinical suspicion of sub / infertility.

Sign in / Sign up

Export Citation Format

Share Document