scholarly journals ASSOCIATION BETWEEN CHRONIC KIDNEY DISEASE AND PLASMA HOMOCYSTEINE LEVEL - A HOSPITAL BASED STUDY

Author(s):  
Dr. Sunil Kumar Aren ◽  
Dr. Vivek Bhardwaj

Background: CKD is defined as the presence of kidney damage, manifested by abnormal albumin excretion or decreased kidney function, quantified by measured or estimated glomerular filtration rate (GFR), that persists for more than 3 months. Methods: The hospital based cross-sectional study was conducted on 100 patients with CKD. Patients fell within the ages of 20 to 85 years and either were with stage 2–5 CKD. They were recruited from the outpatient clinic of the Division of general medicine govt. medical college, Bharatpur (Rajasthan). Patients’ diagnoses and CKD staging were confirmed by an experienced Physician. Results: Mean value of homocysteine level was 15.35 μmol/L in stage 2-3 and 28.34 μmol/L in stage 4-5 of CKD patients. Conclusion: Level of homocysteine increased according to the stages of CKD. Keywords: Homocysteine, GFR, CKD.

Author(s):  
. Dayanandan ◽  
V. Bavaani

Objectives: To assess degree and severity of depression To describe the symptomatic profile of depression Analyse the relation between depression and demographic, predisposing and precipitating factors. Materials and Methods: A cross-sectional study was done on 160 subjects chosen by random sampling technique from the Department of General Medicine of Saveetha Medical College and Hospital using Montgomery-Asberg Depression Rating Scale. Results: 68% of the cases with acute stroke was assessed and found to have depression according to Montgomery-Asberg Depression Rating Scale. Conclusion: Post-Stroke Depression is expected in patients diagnosed with acute stroke.


2016 ◽  
Vol 45 (2) ◽  
pp. 72-74
Author(s):  
Shamima Jahan ◽  
Qazi Shamima Akhter ◽  
Fayeza Karim ◽  
Mir Jakib Hossain ◽  
Tania Yeasmin

Smoking may cause atherosclerosis and acute cardiovascular events and hyperhomocystenemia may found in smokers that play a vital role in development of atherosclerosis and acute cardiovascular events. The present cross sectional study was carried out in the Department of Physiology, Dhaka Medical College, Dhaka between July 2013 to June 2014 to assess the serum homocysteine (Hcy) level in male smokers. A total number of 200 male subjects were selected with age ranging from 20 to 40 years. Among them, 100 male smokers were included in the study group (Group B) and 100 male non-smokers of same age ranging were considered as controls (Group A). Detailed smoking and medical history was taken regarding drug intake and general examinations were done. The mean serum homocysteine level was significantly higher in adult male smoker than that of adult male non smoker (p < 0.001). This study concludes that serum homocysteine level increases in male smokers which may act as risk factor for future cardiovascular diseases and atherosclerosis.Bangladesh Med J. 2016 May; 45 (2): 72-74


Author(s):  
Arvind Visweshwar ◽  
Mohamed Hanifah ◽  
. Murugesan ◽  
. Avudaiappan ◽  
Arun Prakash

Aim: To detect the prevalence of asymptomatic neuropathy using nerve conduction study among alcohol dependence syndrome patients and to investigate the existence or not of correlation between duration, quantity of alcohol consumption and neuropathy. Study Design: Observational cross-sectional study. Place and Duration of Study: Department of General Medicine and Department of Psychiatry, Mahatma Gandhi Medical College and Research Institute, Pondicherry, affiliated to Sri Balaji Vidyapeeth (Deemed to be) University, India between February 2019 and August 2020. Methods: Alcohol dependence syndrome patients, asymptomatic for neuropathy were prospectively included and, patients who were symptomatic and had other comorbid conditions that can cause neuropathy were excluded. Patients were then submitted to nerve conduction studies. In patients who had neuropathy, duration and quantity of alcohol consumption were compared for correlation. Results: This study included 65 male patients who were mostly middle aged heavy drinkers of alcohol. 73.8% (n=48) had neuropathy. Our research showed longer the duration, larger the quantity of alcohol consumption, and higher the Cut-Annoyed-Guilty-Eye (CAGE score), more were the prevalence of neuropathy. This research also used Severity Of Alcohol Dependence Questionnaire (SAD-Q) scoring for screening alcohol dependence which showed patients with neuropathy were moderate drinkers. We did not find correlation with age of patients and neuropathy. Conclusion: This research results like correlation of prevalence of neuropathy and duration of alcohol consumption and quantity of alcohol consumption were in contrast with previous studies on alcoholic neuropathy. This research used SAD-Q scoring for dependence, future researches can throw light on usage of SAD-Q score in asymptomatic neuropathy and the correlation of neuropathy with alcohol consumption.


Author(s):  
BIJAYA KUMAR BEHERA ◽  
SUKANTA KUMAR JENA ◽  
NISARG BEHERA

Objective: The present study was conducted with an objective to identify the etiology of non-traumatic myelopathies of both compressive and non-compressive types with the aid of magnetic resonance imaging (MRI). Methods: This retrospective observational cross-sectional study was conducted on 100 patients with a clinical diagnosis of non-traumatic myelopathy belonging to the age group of 15–75 years from August 2018 to July 2020 in the Departments of General Medicine and Radiodiagnosis of MKCG Medical College and Hospital, Berhampur, Odisha. Detailed history, clinical evaluation, laboratory investigations, and findings of MRI spine and brain were compiled. Results were analyzed using descriptive statistics. Results: Among 100 patients of non-traumatic myelopathy, 65 patients presented with compressive myelopathy and 35 patients with non-compressive myelopathy where 56 patients presented with paraparesis and 44 with quadriparesis. Pott’s spine (n=25, 38.46%) and acute transverse myelitis (ATM) (n=24, 68.57%) were the most common etiologies found in compressive and non-compressive groups, respectively. Conclusion: Pott’s Spine, spondylotic myelopathy, and ATM were the most common etiologies of non-traumatic myelopathy. MRI has proven to be the ultimate imaging modality for their etiological evaluation.


2018 ◽  
Vol 2018 ◽  
pp. 1-8 ◽  
Author(s):  
Seung Wan Hong ◽  
Young Sung Suh ◽  
Dae Hyun Kim ◽  
Mi Kyung Kim ◽  
Hye Soon Kim ◽  
...  

Sasang typology is a traditional Korean medical classification scheme that combines medical management with general medicine and can be applied to chronic diseases. We aimed to analyze differences in Sasang Personality Questionnaire (SPQ) and Sasang Digestive Function Inventory (SDFI) results in patients with diabetes mellitus (DM), hypertension, functional dyspepsia, major depressive disorder (MDD), and adenomyosis. In this cross-sectional study, data were collected at a medical college hospital in South Korea. A total of 248 patients were included: 52 with DM, 47 with hypertension, 36 with functional dyspepsia, 26 with MDD, and 87 with adenomyosis. The subjects took both the SPQ and the SDFI. The outcome measures in this study were body mass index (BMI), SPQ score, and SDFI score. The DM and hypertension groups, which were expected to demonstrate many Taeeum-type traits, exhibited high BMI, high SPQ-Behavior and SDFI-Appetite scores, and low SPQ-Emotionality and SDFI-Digestion scores. The functional dyspepsia group showed low BMI and high scores for SPQ-Behavior, SPQ-Emotionality, SDFI-Digestion, and SDFI-Appetite. The MDD group demonstrated high SPQ-Emotionality and SDFI-Digestion scores, low BMI, and low SPQ-Behavior and SDFI-Appetite scores. The adenomyosis group demonstrated high scores for SPQ-Behavior, SDFI-Digestion, and SDFI-Appetite, low BMI, and low SPQ-Emotionality scores. Different characteristics distinguishing Sasang traits according to chronic diseases were ascertained, especially for Taeeum and Soeum types.


2021 ◽  
pp. 58-60
Author(s):  
S.Hema Akilandeswari ◽  
B. Kavitha ◽  
C.Maghil Belinta

Background:Co-infection of HIV with HBV and HCV can alter the natural history of these hepatotropic viruses leading to chronic hepatitis, cirrhosis and increases the risk of developing hepatocellular carcinoma. Hence this study was conducted to estimate the sero prevalence of HBV and HCV co-infection among the HIV infected individuals and to assess the association of co-infection with liver enzyme levels and CD4+ T cell levels. Methods: This study was conducted as a cross sectional study in the Department of General medicine in Thanjavur Medical College and hospital, Thanjavur, a tertiary care Government teaching hospital during the period of October 2018 to August 2019.A total of 159 HIV cases were included in the study.All the cases were assessed by detailed history, clinical examination,serology for HIV infection.Patients were tested for co-infection with HBV ,HCV and CD4 count.Data was entered and analysed using Graph Pad Prism version 5 software. Results:BMI was significantly low among cases with HIV associated with co-infection compared to HIV infection alone whereas SGOT, SGPT and ALP were significantly high among cases with HBV co-infection compared to HIV infection alone. Conclusion: This shows that there is higher risk of liver disease among the patients with HIV along with co-infection. The risk is further aggravated by exposure to opportunistic infections, alcoholism and anti retro viral drugs. Hence coinfection with HBV or HCV among the HIV seropositive cases should be estimated earlier before treatment with antiretroviral drugs.


2016 ◽  
Vol 2 (1) ◽  
pp. 62-78
Author(s):  
. Hemraj ◽  
Raj Kumar ◽  
Sourabh Kosey ◽  
Amit Sharma ◽  
Nalini Negi

To determine the most common physical side effects experienced by local chemotherapy patients. Their perceptions of these side effects and informational needs from clinical pharmacists were also evaluated. This was a single center, observational cross-sectional study conducted at department of General Surgery, Guru Gobind Singh Medical College and Hospital, Faridkot, Punjab. A face to face interview was conducted. Information collected included chemotherapy related side effects after last chemotherapy experience, the most worrisome side effects, overlooked by healthcare professionals and the preferred method, amount and source of receiving related information. In this study, hundred patients were enrolled out of them 48 were male and 52 were female. When differential calculations was done, common side effects or adverse effects of chemotherapy in the patients of breast, lung cancer, Ovarian Cancer, Colon cancer, Prostate cancer, Lymphoma Cancer, Cervix cancer where there is much irregular medicine intake 57.4% may be due to common problem of joint pain reported by all the patients under study, with the consecutive problem of nausea and vomiting. The high prevalence of chemotherapy related side effects among local patients is a major concern and findings of their perceptions and informational needs may serve as a valuable guide for clinical pharmacists and physicians to help in side effect management. This study shows the common problems reported by the patients when they are suffering from cancer condition, according to their incidence perceptions as experienced by the patient, this will allow the physician and clinical pharmacist to effectively counsel and manage the common symptoms as reported prior to its occurrence in the patient, so that withdrawal can be checked.


2012 ◽  
Vol 6 (1) ◽  
pp. 11-13
Author(s):  
Sushmita Roy ◽  
S.M. Shamsuzzaman ◽  
K.Z. Mamun

Rotavirus is one of the leading causes of pediatric diarrhea globally. Accurate and rapid diagnosis of Rotavirus diarrhea should reduce unnecessary use of antibiotics and ultimately reduce drug resistance. Study was designed for rapid diagnosis of Rotavirus antigen in stool sample by ICT (Immunochromatographic test) as well as to observe the seasonal variation of rotavirus infection. This cross sectional study was carried out in the department of Microbiology, Dhaka Medical College from January 2011 to December 2011. Eighty stool samples were collected from Dhaka Shishu Hospital and Dhaka Medical College Hospital. All samples were tested for rotavirus antigen by ICT. Among 80 patients, 42 (52.5%) samples were positive for rotavirus antigen. Among these 42 positive samples, 30 (71.43%) were from 0-12 months of age group, 10 (23.81%) from 13 to 24 months of age group and rest 2 (4.76%) from 25 to 36 months of age group. Rotavirus Ag was detected in stool samples from January to April and another peak episode from October to December. Considering the importance of Rotavirus associated diarrhea, rapid detection of Rotavirus infection in human is substantially needed and should be routinely practiced.DOI: http://dx.doi.org/10.3329/bjmm.v6i1.19354 Bangladesh J Med Microbiol 2012; 06(01): 11-13


1970 ◽  
Vol 40 (1) ◽  
pp. 18-21 ◽  
Author(s):  
MN Hossain ◽  
Z Rahman ◽  
S Akhter

A cross sectional study was carried out at the department of Forensic Medicine in Dhaka Medical College during the period of January 2008 to December 2009. Data were collected from 3rd copy of the post mortem reports which were preserved in the department of Forensic Medicine with the verbal consent of the doctors who performed autopsy report. During this period total 5114 autopsies were conducted. Out of this 970 cases (19%) were suicidal in nature. It was noticed that all suicidal deaths occurred from 10 years to all age group respectively, but top amongst age group of suicidal deaths occurred in between 21 to 30 years of people. Suicidal deaths are more common in female than male. Suicidal deaths due to hanging is highest, next common causes of death due to organophosphorus compund poisoning. Suicidal deaths by hanging is more in female than male but in poisoning cases male are more lvictimised than female. Objectives of our study are to see the occurrence and methods of suicidal death. DOI: http://dx.doi.org/10.3329/bmj.v40i1.9957 BMJ 2011; 40(1): 18-21


2020 ◽  
Vol 22 (3) ◽  
pp. 141-145
Author(s):  
Krishna Chandra Devkota ◽  
S Hamal ◽  
PP Panta

Pleural effusion is present when there is >15ml of fluid is accumulated in the pleural space. It can be divided into two types; exudative and transudative pleural effusion. Tuberculosis and parapneumonic effusion are the common cause of exudative pleural effusion whereas heart failure accounts for most of the cases of transudative pleural effusion. This study was a hospital based cross sectional study performed at Nepal Medical College during the period of January 2016-December 2016. A total of 50 patients who fulfilled the inclusion criteria were enrolled. Pleural effusion was confirmed by clinical examination and radiology. After confirmation of pleural effusion, pleural fluid was aspirated and was analysed for protein, LDH, cholesterol. The Heffner criteria was compared with Light criteria to classify exudative or transudative pleural effusion. Among 50 patients, 30 were male and 20 were female. The mean age of patient was 45.4±21.85 years. The sensitivity and specificity of using Light criteria to detect the two type of pleural effusion was 100% and 90.9%, whereas using Heffner criteria was 94.87%, 100% respectively(P<0.01). There are variety of causes for development of pleural effusion and no one criteria is definite to differentiate between exudative or transudative effusion. In this study Light criteria was more sensitive whereas Heffner criteria was more specific to classify exudative pleural effusion. Hence a combination of criteria might be useful in case where there is difficulty to identify the cause of pleural effusion.


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