scholarly journals Morphological indicators of blood in cats with panleucopenia

2021 ◽  
Vol 23 (103) ◽  
pp. 21-26
Author(s):  
M. Radzikhovskyi ◽  
O. Dyshkant ◽  
I. Sokulsky ◽  
E. Kolesnik ◽  
D. Prokopchuk
Keyword(s):  
Total Bilirubin ◽  
Multiple Organ ◽  
Creatinine Concentration ◽  
Physiological Limits ◽  
The World ◽  
Modern Methods ◽  
Moral Damage ◽  
Rapid Tests ◽  
Feline Parvovirus ◽  
Hematological And Biochemical Parameters

Ukraine is one of the world leaders in the number of cats among the country's population, and one of the most common diseases is panleukopenia caused by a virus of the Parvoviridae family, which is extremely common among viral diseases and causes significant moral damage to owner animals. Therefore, given the relevance of this issue, the result of our study is to clarify, supplement and summarize the data on hematological and biochemical parameters of blood and erythrocytopoiesis in panleukopenia of cats. The development and improvement of modern methods of immunoprophylaxis and treatment can significantly reduce morbidity and mortality. The study was performed in veterinary clinics of Zhytomyr and Kyiv, blood for the study was taken from the superficial vein of the forearm Anterbrachium, medial subcutaneous vein or subcutaneous tibial vein Saphena. Diagnostic tests to confirm feline parvovirus were performed using rapid tests VetExpert and ELISA and PCR for the presence of parvovirus antigen in private veterinary laboratories “BioSoft” and LLC “Bald” in Kiev. The complex studies carried out indicated that in cats (n = 24) with panleukopenia, changes in the morphological and biochemical composition of the blood are characteristic. A deviation from physiological limits was found, which mainly characterize the functional state of the liver, namely, an increase in the content of total bilirubin (P ≤ 0.01) and total protein (P ≤ 0.01), the development of pancreatitis – taking into account an increase in glucose concentration (P ≤ 0.05) and α-amylase hyperenzymemia (P ≤ 0.001), kidney damage as indicated by an increase in creatinine concentration (P ≤ 0.001) and urea level (P ≤ 0.01). In the course of the research, a slight decrease in indicators of the main erythrocyte indices was established, namely, a decrease in MCHC (P ≤ 0.05), which indicates the development of anemia. As a result of an experimental study of the morphological parameters of blood, a complex pathogenesis of the disease with panleukopenia with multiple organ failure and the development of pathological immunosuppression and hepato-pancreatic-renal syndrome was established.

GENESIS OF LEGAL RESPONSIBILITY OF JUDGES IN UKRAINE

2017 ◽  
Author(s):  
Yaroslav Skoromnyy ◽  
Keyword(s):  
The State ◽  
Judicial System ◽  
Court Decision ◽  
Legal Responsibility ◽  
Criminal Prosecution ◽  
Legal Analysis ◽  
Legal Literature ◽  
Modern Methods ◽  
The Status ◽  
Moral Damage

The article examines the features of the formation (genesis) of legal responsibility of judges in Ukraine (from Kievan Rus to the present day). It has been proven that at present there are many problems regarding the criminal (legal) responsibility of judges. It was found that judges are insufficiently protected from manifestations of criminal prosecution, which, in turn, affects the increase in loyalty to the prosecution, in contrast to the defense in the criminal process. It has been established that today there are no perfect mechanisms for appealing the inaction of judges in court. It was determined that bringing judges to disciplinary responsibility in the High Council of Justice does not fully comply with the requirements of the European Charter on the Status of Judges. Based on the results of the legal analysis of the activities of the institutions of judicial responsibility, it was found that modern methods of bringing judges to justice in Ukraine are imperfect, often contradictory, and in some cases allow judges to avoid responsibility. It has been established that the issue of civil liability of judges for carrying out wrong actions against citizens today requires an urgent solution, since the legal literature does not fully disclose the provisions that govern the conditions, grounds and procedure for holding judges accountable for resolving unfair sentences and implementing illegal actions that entail material and/or moral damage to citizens. It has been determined that for harm caused as a result of an unjust court decision made by a judge, as well as due to the judge's inaction, property liability is imposed on the state, since the judge conducting the proceedings acts on behalf of the state, that is, Ukraine. It was found that today a judge can be brought to disciplinary responsibility in cases determined in accordance with the Law of Ukraine «On the Judicial System and the Status of Judges».

TIRYAQ-E-ARBA (A POLY HERBAL UNANI FORMULATION) IN FIGHTING AGAINST COVID 19 LIKE CONDITIONS – UNANI PERSPECTIVE

2020 ◽  
Vol 13 (1) ◽  
Author(s):  
Nafisa Qibriya Khan ◽  
A. H. Farooqui ◽  
Syed Ayesha Fatima ◽  
Jalil Ahmad ◽  
Tausif S. Khan
Keyword(s):  
Respiratory Infections ◽  
Transmission Rate ◽  
Multiple Organ ◽  
World Health ◽  
Upper Respiratory Tract ◽  
Health Crisis ◽  
Unani Medicine ◽  
The World ◽  
Health Organization ◽  
Almost All

Coronavirus disease 2019 (COVID-19) is a pandemic disease of modern time with unique and rapid transmission rate and affected almost all the nations without respecting any border. Coronavirus disease 2019 (COVID-19) is arguably the biggest health crisis the world has faced in 21st century. It is an infectious disease and declared pandemic by the World Health Organization. The coronavirus disease 2019 (COVID-19) outbreak, which originated in Wuhan, China, has now spread to 192 countries and administrative regions infecting nearly 800,000 individuals of all ages as of 31 March 2020. Though most infected individuals exhibit mild symptoms including fever, upper respiratory tract symptoms, shortness of breath, and diarrhoea, or are asymptomatic altogether, severe cases of infection can lead to pneumonia, multiple organ failure, and death. Globally, at least 7900 deaths have been directly attributed to COVID19, and this number is expected to rise with the ongoing epidemic. This is particularly crucial as the current outbreak involves a new pathogen (SARS-CoV-2), on which limited knowledge exists of its infectivity and clinical profile. Research is in progress on therapeutic efficacy of various agents including anti-malarials (Chloroquine and Hydroxychloroquine), antiviral drugs, and convalescent serum of recovered patients. Unani system of medicine is one of the traditional systems of medicine which is being explored for providing preventive, supportive and rehabilitative care to patients. Unani system of medicine has a detailed description of drugs that are utilized in many infectious diseases, including respiratory infections. Immune response is essential to eliminate virus and to preclude disease progression to severe stages. Therefore, it is important to summarize the evidence regarding the preventive measures, control options such as immune-stimulator and prophylactic treatment in Unani medicine against Covid19. This review summarizes various pharmacological actions of Unani formulation Tiryaq-e-Arba in Unani literature and various reported pharmacological activities which can possibly provide prevention, control and reduction of complications of this deadly disease.

scholarly journals How to Control Covid-19 with a Nanobiotherapy?

2020 ◽  
Keyword(s):  
Intensive Care Unit ◽  
Immune Response ◽  
Acute Respiratory Distress Syndrome ◽  
Distress Syndrome ◽  
Multiple Organ ◽  
World Health ◽  
Shortness Of Breath ◽  
The World ◽  
Health Organization ◽  
Muscle Ache

The outbreak of emerging severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) disease (COVID-19) in China has been brought to global attention and declared a pandemic by the World Health Organization (WHO) on March 11, 2020. In a recent study of Nanshan Chen et al., on patients of Wuhan Jinyintan Hospital, Wuhan, China, from the 99 patients with SARSCoV-2 infection, 51% had chronic diseases and they had symptoms of fever (83%), cough (82%) shortness of breath (31%), muscle ache (11%), fatigue (9%), headache (8%), sore throat (5%), rhinorrhea (4%), chest pain (2%), diarrhea (2%), and nausea and vomiting (1%) [1, 2]. The majority of patients can recover, however, about 25% of patients will progress into severe complications including acute respiratory distress syndrome (ARDS), which may worsen rapidly into respiratory failure, need an intensive care unit (ICU) and even cause multiple organ failure [3]. Depending on the pathophysiological mechanisms supposed to be involved in the development of the various clinical forms of the disease, various types of treatment have been tested with varying degrees of success. We have developed a nanotherapy to block the entry of the virus into the host cell, to reduce its potential for replication and to regulate the immune response against the microbial aggressor [4].

The German Elections of 1928

1928 ◽  
Vol 22 (3) ◽  
pp. 698-705
Author(s):  
James K. Pollock
Keyword(s):  
Political Parties ◽  
The Political ◽  
City Councils ◽  
The People ◽  
The World ◽  
Modern Methods ◽  
Political Consolidation ◽  
National Socialists ◽  
The Right ◽  
Intensive Work

The elections which were held throughout Germany on May 20, 1928, are of considerable interest and importance not only to Germany but also to the rest of the world. These elections, to be sure, did not have the dramatic interest which attended the Reichstag elections of December, 1924. But they deserve attention for a number of reasons: first, because they are the first elections to be held in the Reich under what may be called normal conditions; second, because elections for five Landtags and several city councils were held at the same time; and third, because the elections gave a further test, and supplied additional evidence of the operation, of the German system of proportional representation.Despite the intensive work of the political parties, the people were not aroused to much enthusiasm during the campaign. The old Reichstag was dissolved before Easter, but not until the last week of the campaign could one detect any excitement. Never before had the electors been bombarded with so much printed matter, posters, and, last but not least, loud-speakers and films. All the modern methods of appealing to the voters were tried by the numerous political parties. There were lacking, however, the overpowering issues and the battlecries which were so effective in 1924. Parades, demonstrations, meetings, and all the rest were carried through successfully on the whole, but they were quite dull and uninteresting. Only the two extreme parties, the National Socialists or Hitlerites on the right, and the Communists on the left, could appear enthusiastic. Nevertheless, the lack of what the Germans call a “grosse Parole” and the lack of excitement are not to be deplored; their absence probably indicates progress toward social and political consolidation.

scholarly journals POTENTIAL THERAPIES FOR TREATMENT OF COVID-19

2020 ◽  
Vol 7 (1) ◽  
pp. 062-071
Author(s):  
Beatriz Gasser ◽  
Ricardo Andres Ramirez Uscategui
Keyword(s):  
Clinical Trials ◽  
Distress Syndrome ◽  
Multiple Organ ◽  
The Novel ◽  
Controlled Clinical Trials ◽  
Interferon Β ◽  
The World ◽  
Novel Coronavirus ◽  
Time Point

Since discovery of the novel coronavirus (SARS-CoV-2) in December of 2019, this viral pneumonia originated in Wuhan, China quickly spread around the world. This new disease, called COVID-19 can cause Acute Respiratory Distress Syndrome (ARDS) due to an uncontrolled inflammatory response like sepsis, that leads to multiple organ failure and even death. Several pharmacotherapeutics alternatives are being tested over the world, looking for most diverse drugs that might be able to fight the infection. The objective of this paper is to review the main pharmacotherapeutics techniques development, as remdesivir, chloroquine/hydroxychloroquine, lopinavir plus ritonavir, interferon-β, ivermectin, anticoagulants, convalescent plasma and vaccine, currently undergoing clinical trials in order to evaluate its effectiveness and safety to combat the COVID-19, presenting their characteristics, possible adverse effects and main scientific findings of its potential action. In conclusion, some therapies presented promising in-vitro results or in the treatment of some patients, nonetheless, multicentric blinded placebo controlled clinical trials are necessary to determine their effectiveness, safety, dosage, and best time point of treatment.

The first ascent of Mont Blanc

1955 ◽  
Vol 11 (2) ◽  
pp. 236-255 ◽  
Keyword(s):  
Great Britain ◽  
Mount Everest ◽  
Private Correspondence ◽  
The World ◽  
Modern Methods

When Mount Everest was finally conquered by Edmund Hillary and Tenzing Norkey on 29 May 1953 the event aroused enormous interest, and all the resources of ancient and modern methods of communication by runner, telegraph, and wireless were available to spread the news rapidly all over the world. It arrived in Great Britain three days later, during the night of 1/2 June and one of its first recipients was the Queen. Conditions were very different when Mont Blanc was first ascended by Dr Michel-Gabriel Paccard and Jacques Balmat on 8 August 1786. The news was carried by messenger from Chamonix to Geneva for the information of H. B. de Saussure who received it on the morning of 10 August. Thereafter the spread of the news was sporadic, uncertain and slow, depending on the private correspondence of de Saussure and his friends and of tourists who chanced to be at Chamonix at the time. It was first published in the Leipziger Zeitung of 23 August 1786, but the first publication in Great Britain appears to have been in The Scots Magazine for November of that year. And yet it also was a great and important event.

PROFESSIONAL DEVELOPMENT DRIVERS AS ONE OF DIRECTIONS TO REDUCE ACCIDENT ON ROAD TRANSPORT

2016 ◽  
Vol 3 (1) ◽  
pp. 201-204 ◽  
Author(s):  
Волков ◽  
V. Volkov ◽  
Лебедев ◽  
E. Lebedev
Keyword(s):  
Professional Development ◽  
Traffic Accident ◽  
Road Transport ◽  
Professional Activity ◽  
Accident Rate ◽  
Probability Of Occurrence ◽  
The World ◽  
Modern Methods ◽  
The Impact

The problem of raising the qualification of drivers in the course of their professional activity. The aim is to study modern methods of training of drivers used throughout the world and identify new ways to reduce the accident rate in road transport. This will assess the impact of drivers´ qualification on the probability of occurrence of a traffic accident.

scholarly journals Using Crime Control Mechanisms in Yoruba Traditional Society as a Template for Redressing Security Challenges in Nigeria

2021 ◽  
Author(s):  
Peter Ó̩̩̩̩̩ ke Olúse ̩̩̩̩̩́ ̩̩̩̩̩́ ̩̩̩̩̩́ ̩̩̩̩̩́ ̩̩̩̩̩́ gun
Keyword(s):  
Social Development ◽  
Qualitative Method ◽  
Crime Control ◽  
Traditional Society ◽  
Control Mechanisms ◽  
The People ◽  
Security Challenges ◽  
The World ◽  
Modern Methods ◽  
Developed Nations

Crime and its attendant fatalities has become a burning issue in Nigeria in recent times. It is a phenomenon that is bedeviling the nation and steps taken by government to prevent it seem inadequate as it continues to spread like a dry season fire. Existing studies on crime and its control have focused mainly on the use of modern methods which are at variance with the cultures of the various societies, while little attention is also paid to the crime control mechanisms of the traditional Yoruba society. The inability of government to tackle the menace of crime has led to palpable fears among the people as security of lives and property is perpetually threatened. This has impacted negatively on the country that is striving to be among the developed nations in the world. A qualitative method of research was adopted for this brief study. The paper argues that crime that has become the order of the day in Nigeria, came as a result of inter alia unemployment, poverty, selfishness and greed. This paper proffers a solution by proposing the use of traditional Yoruba crime control mechanisms with the modern one, side by side, to fight crime in Nigeria in order to foster the rapid economic and social development that everybody is longing for.

scholarly journals A Survey of the Application of Artifical Intellegence on COVID-19 Diagnosis and Prediction

2021 ◽  
Vol 11 (6) ◽  
pp. 7824-7835
Author(s):  
H. Alalawi ◽  
M. Alsuwat ◽  
H. Alhakami
Keyword(s):  
Machine Learning ◽  
State Of The Art ◽  
Future Research ◽  
Classification Algorithms ◽  
Classification Methods ◽  
Research Directions ◽  
The World ◽  
Modern Methods ◽  
Future Research Directions ◽  
Class Labels

The importance of classification algorithms has increased in recent years. Classification is a branch of supervised learning with the goal of predicting class labels categorical of new cases. Additionally, with Coronavirus (COVID-19) propagation since 2019, the world still faces a great challenge in defeating COVID-19 even with modern methods and technologies. This paper gives an overview of classification algorithms to provide the readers with an understanding of the concept of the state-of-the-art classification algorithms and their applications used in the COVID-19 diagnosis and detection. It also describes some of the research published on classification algorithms, the existing gaps in the research, and future research directions. This article encourages both academics and machine learning learners to further strengthen the basis of classification methods.

scholarly journals Laboratory testing for COVID-19 in suspected human cases and the impact of corona virus pandemic on the global health system

2020 ◽  
Vol 5 (4) ◽  
pp. 498-504
Author(s):  
Debashis Mania ◽  
T.K. Mandal ◽  
A.K. Bera ◽  
Brig. Rajiv Sethi
Keyword(s):  
Laboratory Testing ◽  
Multiple Organ ◽  
Human Beings ◽  
Indian Health ◽  
Corona Virus ◽  
Organ Systems ◽  
The World ◽  
The Impact ◽  
Organ Invasion ◽  
Different Parts

COVID-19, coronavirus (SARS-CoV-2) infection has become pandemic after first appearing in Wuhan, China in December 2019. It destroyed the life of millions of people throughout the different parts of Europe, America, Asia and others in the world. Various groups of scientists throughout the globe have claimed on trialing for the corona vaccine and for finding out suitable medication for the treatment of COVID-19. No vaccine or medicines are successfully reported to short out the issue for saving the valuable life of human beings, till date. The mechanism of SARS-CoV-2 infection and organ invasion are not understood and it creates difficulty in clinical diagnosis and treatment of corona patients. The pathogenic mechanism of SARS-CoV-2 infection is not very much clear and it may invade multiple organ systems of respiratory, digestive and hematological in a confirmed case. The impact of corona virus outbreak on the global and Indian health systems is also reviewed herewith.

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