ANALYSIS OF THE STABILITY OF ROLA PLANTS RECOMBINANT ONCOGEN DURING LONG-TERM CULTIVATION OF RUBIA CORDIFOLIA L. CELL CULTURE

SummaryThe International Reference Preparation of human brain thromboplastin coded 67/40 has been thought to show evidence of instability. The evidence is discussed and is not thought to be strong; but it is suggested that it would be wise to replace 67/40 with a new preparation of human brain, both for this reason and because 67/40 is in a form (like Thrombotest) in which few workers seem to use human brain. A �plain� preparation would be more appropriate; and a freeze-dried sample of BCT is recommended as the successor preparation. The opportunity should be taken also to replace the corresponding ox and rabbit preparations. In the collaborative study which would be required it would then be desirable to test in parallel the three old and the three new preparations. The relative sensitivities of the old preparations could be compared with those found in earlier studies to obtain further evidence on the stability of 67/40; if stability were confirmed, the new preparations should be calibrated against it, but if not, the new human material should receive a calibration constant of 1.0 and the new ox and rabbit materials calibrated against that.The types of evidence available for monitoring the long-term stability of a thromboplastin are discussed.

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Application of the method of mathematical modeling for forecasting channel deformations at the underwater crossing of the main pipeline

SCIENCE & TECHNOLOGIES OIL AND OIL PRODUCTS PIPELINE TRANSPORTATION ◽

10.28999/2541-9595-2020-10-6-599-609 ◽

2020 ◽

Vol 10 (6) ◽

pp. 599-609

Author(s):

Valery А. Gruzdev ◽

◽

Georgy V. Mosolov ◽

Ekaterina A. Sabayda ◽

◽

...

Keyword(s):

Mathematical Modeling ◽

Mathematical Model ◽

Roughness Coefficient ◽

Computational Domain ◽

Channel Deformations ◽

Geological Surveys ◽

Kuban River ◽

The Stability ◽

Protective Structures

In order to determine the possibility of using the method of mathematical modeling for making long-term forecasts of channel deformations of trunk line underwater crossing (TLUC) through water obstacles, a methodology for performing and analyzing the results of mathematical modeling of channel deformations in the TLUC zone across the Kuban River is considered. Within the framework of the work, the following tasks were solved: 1) the format and composition of the initial data necessary for mathematical modeling were determined; 2) the procedure for assigning the boundaries of the computational domain of the model was considered, the computational domain was broken down into the computational grid, the zoning of the computational domain was performed by the value of the roughness coefficient; 3) the analysis of the results of modeling the water flow was carried out without taking the bottom deformations into account, as well as modeling the bottom deformations, the specifics of the verification and calibration calculations were determined to build a reliable mathematical model; 4) considered the possibility of using the method of mathematical modeling to check the stability of the bottom in the area of TLUC in the presence of man-made dumping or protective structure. It has been established that modeling the flow hydraulics and structure of currents, making short-term forecasts of local high-altitude reshaping of the bottom, determining the tendencies of erosion and accumulation of sediments upstream and downstream of protective structures are applicable for predicting channel deformations in the zone of the TLUC. In all these cases, it is mandatory to have materials from engineering-hydro-meteorological and engineering-geological surveys in an amount sufficient to compile a reliable mathematical model.

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Influence of internal and external risks on sustainability of financial system of Аltai krai

Voprosy regionalnoj ekonomiki ◽

10.21499/2078-4023-2018--4-133-136 ◽

2018 ◽

Vol 35 (4) ◽

pp. 133-136

Author(s):

R. N. Ibragimov

Keyword(s):

Sustainable Development ◽

Financial Stability ◽

Management Strategy ◽

Financial System ◽

Risk Management Strategy ◽

The Sustainable Development ◽

The Stability ◽

The Impact

The article examines the impact of internal and external risks on the stability of the financial system of the Altai Territory. Classification of internal and external risks of decline, affecting the sustainable development of the financial system, is presented. A risk management strategy is proposed that will allow monitoring of risks, thereby these measures will help reduce the loss of financial stability and ensure the long-term development of the economy of the region.

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Long-term vegetation restoration promotes the stability of the soil micro-food web in the Loess Plateau in North-west China

CATENA ◽

10.1016/j.catena.2021.105293 ◽

2021 ◽

Vol 202 ◽

pp. 105293

Author(s):

Yang Wu ◽

WenJing Chen ◽

Wulan Entemake ◽

Jie Wang ◽

HongFei Liu ◽

...

Keyword(s):

Food Web ◽

Loess Plateau ◽

Vegetation Restoration ◽

The Loess Plateau ◽

West China ◽

North West ◽

The Stability

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An unusually low density ultra-short period super-Earth and three mini-Neptunes around the old star TOI-561

Monthly Notices of the Royal Astronomical Society ◽

10.1093/mnras/staa3728 ◽

2020 ◽

Author(s):

G Lacedelli ◽

L Malavolta ◽

L Borsato ◽

G Piotto ◽

D Nardiello ◽

...

Keyword(s):

Transit Time ◽

Time Variation ◽

Planetary System ◽

Radial Velocities ◽

Low Density ◽

Outer Planets ◽

Short Period ◽

The Stability

Abstract Based on HARPS-N radial velocities (RVs) and TESS photometry, we present a full characterisation of the planetary system orbiting the late G dwarf After the identification of three transiting candidates by TESS, we discovered two additional external planets from RV analysis. RVs cannot confirm the outer TESS transiting candidate, which would also make the system dynamically unstable. We demonstrate that the two transits initially associated with this candidate are instead due to single transits of the two planets discovered using RVs. The four planets orbiting TOI-561 include an ultra-short period (USP) super-Earth (TOI-561 b) with period Pb = 0.45 d, mass Mb = 1.59 ± 0.36 M⊕ and radius Rb = 1.42 ± 0.07 R⊕, and three mini-Neptunes: TOI-561 c, with Pc = 10.78 d, Mc = 5.40 ± 0.98 M⊕, Rc = 2.88 ± 0.09 R⊕; TOI-561 d, with Pd = 25.6 d, Md = 11.9 ± 1.3 M⊕, Rd = 2.53 ± 0.13 R⊕; and TOI-561 e, with Pe = 77.2 d, Me = 16.0 ± 2.3 M⊕, Re = 2.67 ± 0.11 R⊕. Having a density of 3.0 ± 0.8 g cm−3, TOI-561 b is the lowest density USP planet known to date. Our N-body simulations confirm the stability of the system and predict a strong, anti-correlated, long-term transit time variation signal between planets d and e. The unusual density of the inner super-Earth and the dynamical interactions between the outer planets make TOI-561 an interesting follow-up target.

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Effect of Photoinitiator on Precursory Stability and Curing Depth of Thiol-Ene Clickable Gelatin

Polymers ◽

10.3390/polym13111877 ◽

2021 ◽

Vol 13 (11) ◽

pp. 1877

Author(s):

Kai-Hung Yang ◽

Gabriella Lindberg ◽

Bram Soliman ◽

Khoon Lim ◽

Tim Woodfield ◽

...

Keyword(s):

Mechanical Properties ◽

Visible Light ◽

Rheological Properties ◽

Swelling Ratio ◽

Sodium Persulfate ◽

Photo Polymerization ◽

Gelation Kinetics ◽

The Stability ◽

Over Time

Recent advances highlight the potential of photopolymerizable allylated gelatin (GelAGE) as a versatile hydrogel with highly tailorable properties. It is, however, unknown how different photoinitiating system affects the stability, gelation kinetics and curing depth of GelAGE. In this study, sol fraction, mass swelling ratio, mechanical properties, rheological properties, and curing depth were evaluated as a function of time with three photo-initiating systems: Irgacure 2959 (Ig2959; 320–500 nm), lithium phenyl-2,4,6-trimethylbenzoylphosphinate (LAP; 320–500 nm), and ruthenium/sodium persulfate (Ru/SPS; 400–500 nm). Results demonstrated that GelAGE precursory solutions mixed with either Ig2959 or LAP remained stable over time while the Ru/SPS system enabled the onset of controllable redox polymerization without irradiation during pre-incubation. Photo-polymerization using the Ru/SPS system was significantly faster (<5 s) compared to both Ig2959 (70 s) and LAP (50 s). Plus, The Ru/SPS system was capable of polymerizing a thick construct (8.88 ± 0.94 mm), while Ig2959 (1.62 ± 0.49 mm) initiated hydrogels displayed poor penetration depth with LAP (7.38 ± 2.13 mm) in between. These results thus support the use of the visible light based Ru/SPS photo-initiator for constructs requiring rapid gelation and a good curing depth while Ig2959 or LAP can be applied for photo-polymerization of GelAGE materials requiring long-term incubation prior to application if UV is not a concern.

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Carrier-microencapsulation using Al-catecholate complex to suppress arsenopyrite oxidation: Evaluation of the coating stability under simulated weathering conditions

MATEC Web of Conferences ◽

10.1051/matecconf/201926806002 ◽

2019 ◽

Vol 268 ◽

pp. 06002 ◽

Cited By ~ 1

Author(s):

Kensuke Seno ◽

Ilhwan Park ◽

Carlito Tabelin ◽

Kagehiro Magaribuchi ◽

Mayumi Ito ◽

...

Keyword(s):

Protective Coating ◽

Sulfide Mineral ◽

Sulfide Minerals ◽

Low Ph ◽

Oxidation Products ◽

Arsenic Sulfide ◽

Catecholate Complex ◽

Coating Stability ◽

The Stability

Arsenopyrite (FeAsS) is the most common primary arsenic-sulfide mineral in nature, and its oxidation causes the release of toxic arsenic (As). To mitigate these problems, carrier-microencapsulation (CME), a technique that passivates sulfide minerals by covering their surfaces with a protective coating, has been developed. In the previous study of authors on CME, Al-catecholate complex significantly suppressed arsenopyrite oxidation via electron donating effects of the complex and the formation of an Al-oxyhydroxide coating. For the application of this technique to real tailings, however, further study should be carried out to elucidate long-term effectiveness of the coating to suppress arsenopyrite oxidation. This study investigates the stability of the coating formed on arsenopyrite by Al-based CME using weathering tests. The Al-oxyhydroxide coating suppressed arsenopyrite oxidation until about 50 days of the experiment, but after this, the amounts of oxidation products like dissolved S and As increased due to the gradual dissolution of the coating with time as a result of the low pH of leachate. This suggests that co-disposal of Al-based CME-treated arsenopyrite with minerals that have appropriate neutralization potentials, so that the pH is maintained at around 5 to 8 where Al-oxyhydroxide is stable.

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Design and development of microbioreactors for long-term cell culture in controlled oxygen microenvironments

Biomedical Microdevices ◽

10.1007/s10544-011-9592-9 ◽

2011 ◽

Vol 14 (1) ◽

pp. 145-152 ◽

Cited By ~ 47

Author(s):

Hasan E. Abaci ◽

Raghavendra Devendra ◽

Quinton Smith ◽

Sharon Gerecht ◽

German Drazer

Keyword(s):

Cell Culture ◽

Design And Development

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ROBUST STABILITY, STABILISATION AND H-INFINITY CONTROL FOR PREMIUM-RESERVE MODELS IN A MARKOVIAN REGIME SWITCHING DISCRETE-TIME FRAMEWORK

Astin Bulletin ◽

10.1017/asb.2016.13 ◽

2016 ◽

Vol 46 (3) ◽

pp. 747-778 ◽

Cited By ~ 3

Author(s):

Lin Yang ◽

Athanasios A. Pantelous ◽

Hirbod Assa

Keyword(s):

Discrete Time ◽

Regime Switching ◽

Structural Changes ◽

Linear Matrix ◽

H Infinity Control ◽

R Process ◽

The Stability ◽

Markovian Regime Switching ◽

Markovian Regime

AbstractThe premium pricing process and the medium- and long-term stability of the reserve policy under conditions of uncertainty present very challenging issues in relation to the insurance world. Over the last two decades, applications of Markovian regime switching models to finance and macroeconomics have received strong attention from researchers, and particularly market practitioners. However, relatively little research has so far been carried out in relation to insurance. This paper attempts to consider how a linear Markovian regime switching system in discrete-time could be applied to model the medium- and long-term reserves and the premiums (abbreviated here as the P-R process) for an insurer. Some recently developed techniques from linear robust control theory are applied to explore the stability, stabilisation and robust H∞-control of a P-R system, and the potential effects of abrupt structural changes in the economic fundamentals, as well as the insurer's strategy over a finite time period. Sufficient linear matrix inequality conditions are derived for solving the proposed sub-problems. Finally, a numerical example is presented to illustrate the applicability of the theoretical results.

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Effect of Load Carrying on Local Dynamic Stability

Proceedings of the Human Factors and Ergonomics Society Annual Meeting ◽

10.1177/154193120705101509 ◽

2007 ◽

Vol 51 (15) ◽

pp. 909-913 ◽

Cited By ~ 2

Author(s):

Jian Liu ◽

Thurmon E. Lockhart ◽

Kevin Granata

Keyword(s):

Dynamic Stability ◽

Load Condition ◽

Local Dynamic ◽

Fall Injuries ◽

Local Dynamic Stability ◽

Load Carrying ◽

Trunk Acceleration ◽

The Stability ◽

Major Factors

Occupational load carrying tasks are considered one of the major factors contributing to slip and fall injuries. The objective of the current study was to explore the feasibility to assess the stability changes associated with load carrying by local dynamic stability measures. Twenty-five young participants were involved in a treadmill walking study, with their trunk acceleration profiles measured wirelessly by a tri-axial accelerometer. Finite time local dynamic stability was quantified by maximum Lyapunov exponents (maxLE). The results showed a significant increase in long term maxLE in load condition, indicating the declined local dynamic stability due to the load carrying. Thus, current study confirmed the discriminative validity and sensitivity of local dynamic stability measure and its utility in the load carrying scenario.

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