scholarly journals Clinical and Investigation Profile of Subacute Sclerosing Panencephatitis (SSPE): An Analysis of Twenty Cases

1970 ◽  
Vol 17 (2) ◽  
pp. 72-77
Author(s):  
NC Saha ◽  
N Sultana ◽  
MAH Mollah ◽  
L Yasmin ◽  
S Anwar

Objective: To identify common clinical features, sociodemographic characteristics and laboratory parameters of diagnosed cases of Subacute Sclerosing Panencephalitis.Design: Cross sectional descriptive type of study.Setting: Department of Paediatrics, Dhaka Medical College Hospital.Study period: January 2006 to December 2008.Subjects: Twenty clinically diagnosed patients of SSPE.Results: The mean age at presentation was 8 years. Male: Female ratio was 19:1. Most of the patients came from lower socio-economic group (70%). Forty five percent had history of primary measles infection and seventy percent were vaccinated against measles. Most common presenting features were fall to ground (95%), cognitive decline (85%), myoclonic seizures (80%), altered speech (70%), gait disturbance (60%), personality changes (55%), dysphagia (50%) and less commonly blindness (20%). EEG showed abnormal findings in 100% of patients who underwent this test. Measles specific IgG antibody in CSF was positive in 90% cases. Neuroimaging findings were abnormal in 43% cases.Conclusion: The diagnosis of SSPE should be considered in children presenting with deteriorating milestones of development especially cognition and behavior, fall to ground along with myoclonic jerks in an endemic country for measles infection. Investigations like CSF and serum antibody to measles virus and characteristic EEG changes may help further in the diagnosis. Key words: SSPE; Myoclonic jerks; Milestones regression; Measles antibody; EEG. DOI: 10.3329/jdmc.v17i2.6586J Dhaka Med Coll. 2008; 17(2) : 72-77

2019 ◽  
Vol 14 (1) ◽  
pp. 73-77
Author(s):  
Masuma Ahmed Salsabil ◽  
Ashesh Kumar Chowdhury ◽  
Debashish Saha ◽  
Arif Ahmed Khan ◽  
Sazia Sultana

Introduction: The development of anti-RBC antibodies (alloantibodies and/or autoantibodies) can significantly complicate transfusion therapy, particularly in patients needed repeated transfusion. Objectives: To find out the prevalence of alloantibodies and autoantibodies in repeatedly transfused patients so that serious hazards due to immune reaction may be avoided. Materials and Methods: This descriptive cross-sectional study was carried out in Department of Immunology, BIRDEM and Armed Forces Institute of Pathology (AFIP) during the period of July 2015 to June 2016. Total 370 patients who had received at least five units of transfusions were enrolled in this study but known patients of auto immune haemolytic anaemia, patients in whom antibody was previously detected and pregnant women were excluded from the study. Blood grouping and Direct Anti-globulin Test (DAT) were performed with cell suspension using a poly-specific Coombs reagent. In cases of a positive DAT, further investigation using specific monoclonal reagents to detect IgG or a complement (C3d) was carried out. Serum was used to detect red cell alloantibodies using standard blood bank methods. Antibody identification was performed in antibody screening positive samples using red cell Identicells. Results: Maximum 132 (35.7%) patients were in the age group 1-10 years. The male-female ratio was 1.2:1. Among 370 total patients 290 were HHA and 80 were non-HHA. Antibody was detected in only 17(4.59%) patients. Among the Hereditary Haemolytic Anaemia (HHA) patients it was 11 (3.79%) but among the non-HHA patients it was 6(7.5%). Out of 8 auto-antibodies, 5 were anti IgG followed by 3 were anti C3d. Out of 14 alloantibodies, 4(28.6%) were anti E, 3(21.4%) were anti K and in 3(21.4%) cases specificity of alloantibody was not detected. Conclusion: Prevalence of anti-RBC antibodies was not so uncommon in multiple transfused patients. Journal of Armed Forces Medical College Bangladesh Vol.14(1) 2018: 73-77


2017 ◽  
Vol 6 (2) ◽  
pp. 12-14
Author(s):  
Nilufar Begum ◽  
Amdadul Haque ◽  
Fatema Akhter Tumpa

This cross sectional study was done at department of Transfusion Medicine in Community Based Medical College (CBMCB) to know the Prevalence of ABO blood group and Rh group systems among the students selected for admission into CBMCB. Sample size was 555. Male female ratio was 67:33 with mean age was ±19 years. Maintaining aseptic precaution blood samples were collected by venepuncture with disposable syringe without anticoagulant. Antigen-antibody agglutination test was done in slide method for ABO and Rh(D) blood grouping by mixing individual blood sample with Anti A, Anti -B, Anti-D human antisera. Results were taken by visually and under microscope in low power. Blood group differs person to person due to genetically determined antigen. This study showed highest frequency of blood group B (33.5%) followed by O (32.5 %), A (23.37%) and AB (10.63%) in ABO system and In Rhesus system, frequency of Rh-positive was 97.12% and Rh-negative was 2.88%. Results were comparable with different foreign studies. Fair blood grouping assist the safe blood transfusion and reduce the morbidity and mortality considerably. CBMJ 2017 July: Vol. 06 No. 02 P: 12-14


2016 ◽  
Vol 11 (1) ◽  
pp. 23-25 ◽  
Author(s):  
Radheshyam Saha ◽  
MM Shahin Ul Islam ◽  
Ahmed Manadir Hossain ◽  
Mohammad Rafiqul Kabir ◽  
Abdullah Al Mamun ◽  
...  

Stroke is one of the most common medical emergency. A total number of 100 randomly selected clinically and CT proven acute stroke patients were studied at medicine and neurology ward of Faridpur Medical College Hospital (FMCH), Faridpur from January to July, 2014 with a view to study the clinical features and risk factors of Stroke. Among 100 patients, stroke was found most commonly in 59-70 years age group. Ischaemic stroke was 56%, haemorrhagic stroke was 39% and haemorrhagic infarct was 5%. Most of the patients were male with male-female ratio was 1.6:1. The commonest risk factor was hypertension found in 60%, diabetes mellitus found in 17%, smoking was present in 54% patients and dyslipidaemia was present in 22% cases. History of heart disease (Myocardial infarction was present in 2% patients, valvular heart disease was present in 4% patients) was present in 6% patients. The commonest presentation in both ischaemic and haemorrhagic stroke was hemiplegia (61%). Headache (14%) and vomiting (10%) were found to be more common accompaniment in haemorrhagic stroke. Loss of consciousness was present in 34% patients. Alcohol intake was not found in any patient.Faridpur Med. Coll. J. Jan 2016;11(1): 23-25


2017 ◽  
Vol 7 (2) ◽  
pp. 17-22
Author(s):  
Syed Golam Samdani ◽  
Tahmina Begum

This descriptive cross-sectional study was conducted to explore the status of professionalism regarding knowledge, attitude and practice among intern doctors of different medical college Hospitals in Bangladesh. Study period was July 2015 June 2016.Sample size was 300 and convenient sampling technique was adopted. Study was carried out among all Bangladeshi intern doctors of 4 governments and 2 non-governments selected medical college Hospitals of Dhaka and outside Dhaka. Total 300 intern doctors responded to a self-administered questionnaire. Male female ratio was almost 1:1. Concept of professionalism and level of knowledge regarding its various aspects are not satisfactory in large extends. But attitude towards most of the major principles of professionalism are as much as positive like USA and UK physicians. However, regarding honesty with patients, one statement like physicians should disclose all significant medical errors to affected patients and/or guardians, only 36.9% agreed with this. Similarly, only 43% agreed the statement of re-certification examination to maintain professional competence. Regarding attitude and practice of major attributes & responsibilities of professionalism there is no significant difference (p>0.05) between male and female intern doctors working in different medical college hospitals; but regarding practice there is a significant difference (p<0.05) among intern doctors working in government and non-government hospitals. This study recommended that institutional agreement should be on a definition, setting expectations & curriculum framework regarding professionalism to increase scope of teaching & learning in our undergraduate & post-graduate students.Bangladesh Journal of Medical Education Vol.7(2) 2016: 17-22


2016 ◽  
Vol 21 (2) ◽  
pp. 85-89
Author(s):  
Md Nazmul Islam ◽  
Dipankar Lodh ◽  
Mohammad Mamun Siddiqui ◽  
AF Mohiuddin Khan ◽  
Kazi Meherunnesa

A Cross-Sectional Study was carried out from July 2006 to June 2007 at Department of Otolaryngology and Head-Neck Surgery of Dhaka Medical College Hospital, Dhaka. Data was collected from 150 patients with histologically diagnosed Hypopharyngeal carcinoma. Results of this study showed that hypopharyngeal carcinoma affects more in fifth (36.7%) and sixth (27.4%) decades of life. It was found that male were highly predominant to develop hypopharyngeal carcinoma and male female ratio was 9:1. People with lower educational level were found to be affected more by hypopharyngeal carcinoma. In this study 86 percent patients had history of smoking. Mean duration of smoking was 38.0±23.6 years. This study found that the key symptoms of hypopharyngeal carcinoma was dysphagia, pain and neck mass. In this study 83.5 percent patients presented with palpable lymph node and most (76.6%) of them were in level II. Pyriform fossa was found to be the commonest site (83.3%). In this study all malignancy in hypopharynx was histopathologically squamous cell carcinomaBangladesh J Otorhinolaryngol; October 2015; 21(2): 85-89


Author(s):  
Nirmal Verma ◽  
Nitin Kamble ◽  
Dhiraj Bhawnani ◽  
Kiran Makade ◽  
Monika Dengani ◽  
...  

Background: Patient expression is an important source of information in screening for problems and developing an effective plan of action for quality improvement in health care organizations. Assessing satisfaction has been mandatory for quality control of any hospital, which has resulted in an increasing number of projects devoted to the concept of satisfaction and determinant of patient satisfaction.Methods: The present Cross sectional Observational Hospital based study was conducted in Government Medical College Hospital, Rajnandgaon (C.G.) India during April 2016 to September 2016. A sample of 200 patients was taken who were admitted in different Indoor Patients Department of Clinical departments. Patients were selected according to inclusion and exclusion criteria. The information from the patients on various aspects of patient’s satisfaction like admission procedure, communication with staff, physical care, test and operation help availability, cleanliness, privacy related issues and overall satisfaction was obtained by interview with patients based on the semi structured questionnaire proforma.Results: In the present study, among IPD patient Male: Female ratio was 3:2 approx. Helpfulness of person at registration desk was ranked very good by 93% subject. Wheelchair was available for most of the patients (95%) but its availability when needed was ranked very good by 76% patients only. Majority of patient were satisfied with the behavior of the lab technician (89%), availability of lab results on given time (81%).Conclusions: This study shows that patients admitted in the various wards of hospital were satisfied with the quality of professional services by doctors, nursing and paramedical staff but problem lies with the availability of basic amenities. Overall present study shows that assessing satisfaction of patients is simple, easy and cost effective way for evaluating the hospital services.


2020 ◽  
Vol 7 (3) ◽  
pp. 561
Author(s):  
Chidambaranathan S. ◽  
Madhubalan T. ◽  
Harivasudevan S.

Background: Febrile seizures are the most common and benign convulsive disorder in childhood and a frequent cause of emergency hospital admission  Febrile Seizures (FS) are age-dependent and are rare before the age of 9 months and after 5 years of age, the peak age of onset is 14-18months. To assess the clinical profile in children with febrile seizures and compare these values with febrile children without seizures.Methods: The study included children admitted with bronchiolitis in between during the period of August 2018 to March 2019 at Department of Pediatrics, Raja Muthiah Medical College and Hospital. It is a case-control study. The study group includes 50 cases (febrile seizures) and 50 controls (fever without seizures) aged 6months to 5 years (6-60 months) attending the pediatric out-patient department.Results: 54% of the cases were male (27) and 46% of the cases were female (23). Male: female ratio was 1.17:1. Mean temperature in cases and controls were 101.61±1.31 °F and 101.17±0.86 °F respectively. The difference between the two groups was not statistically significant (p-value >0.05). duration of seizure was <5 minutes in 80% of cases (40/50) and >5mins in 20% of the cases (10/50).Conclusions: Simple febrile seizures may slightly increase the risk of developing epilepsy, but have no adverse effects on behaviour, scholastic performance, or neurocognition. The risk of developing epilepsy is increased further in children with a history of complex febrile seizures. A strong association exists between febrile status epilepticus or febrile seizures characterized by focal symptoms and later development of temporal lobe epilepsy.


2015 ◽  
Vol 22 (05) ◽  
pp. 621-626
Author(s):  
Mariam Arif ◽  
Mushtaq Ahmed ◽  
Syed Hamad Rasool

The specter of road traffic injuries takes a greater toll on human life every dayon our roads. Objectives: To analyze the demographic and injury profile of autopsy caseswith an alleged history of RTA (Road traffic accidents). Design: Retrospective study. Setting:Forensic Medicine Department of Nishtar Medical College, Multan. Period: January 2010 toDecember 2013. Material and Methods: 116 autopsy cases with an alleged history of RTA.Data collected pertaining to history, epidemiology, details of injuries and cause of death etc.was statistically analyzed on SPSS version17. Results: Out of 116 autopsies on RTA victims,46.55% victims were between 21-40 years with male: female ratio of 1.9:1. Maximum numberof accidents occurred during day time between 6 am and 5:59 pm (62.06%). 79.31% died atthe site of accidents. Pedestrians were the commonest victims (81.89%). Four wheelers causedmost of RTA 51(43.96%). The cause of death was opined to be head injury in 45.68% of cases.Conclusion: Addressing road safety in a comprehensive manner necessitates the involvementof multiple sectors, such as health, transport and police.


2020 ◽  
Vol 27 (10) ◽  
pp. 2253-2259
Author(s):  
Zaid Umer ◽  
Irum Hayat ◽  
Muhammad Waseem ◽  
Nauman Aziz ◽  
Hafiza Swaiba Afzal ◽  
...  

Objectives: To know the frequency of obstructive pattern on spirometry in asymptomatic chronic smokers. Study Design: Cross-sectional study. Settings: Department of Pulmonology, Sahiwal Medical College Sahiwal. Period: 1st Nov, 2019 to 1st May 2020. Materials & Methods: A total of 205 chronic smokers aged 30-60 years were included. Patients with history of Ischemic heart disease, previously diagnosed cases of COPD and asthma were excluded. Spirometry was done by using portable spirometer by consultant pulmonologist (at least 2 years of post-fellowship experience) and obstructive pattern (COPD) was noted. Results: Majority males with ages between 41 to 50 years( mean age 47.78 ± 4.90 years)  out of the 205 patients, 137 (66.83%) were male and 68 (33.17%) were females with male to female ratio of 2:1. Mean duration of smoking was 8.81 ± 4.67 years. Mean height was 161.81 ± 9.23 cm. Mean weight was 78.81 ± 5.67 kg. Mean BMI was 26.21 ± 5.39 kg/m2. In this study, frequency of obstructive COPD on spirometry in asymptomatic chronic smokers was found in 29 (14.15%) patients. Conclusion: This study established that frequency of obstructive pattern on spirometry in asymptomatic chronic smokers is high.


2019 ◽  
Vol 24 (2) ◽  
pp. 125-130
Author(s):  
Ahmmad Taous ◽  
Sheikh Md Rafiqul Hossain ◽  
Md Mustafizur Rahman

Background: Information about causes or related factors involving voice change was studied mainly in central tertiary level hospitals previously, not in hospital in peripheral districts in Bangladesh Objective: To find out and evaluate the etiological factors of hoarseness of voice irrespective of age and sex. Setting: Pabna medical college, a 250 bedded hospital in Bangladesh Methods: This was a cross sectional, non- randomized and longitudinal study conducted from 1st august 2011 to July 2017. All the patients with history of hoarseness underwent clinical examination, routine as well as special investigation to find the diagnosis. The final results were analyzed by simple manual analysis with frequency and percentage using SPSS program in 2017. Results: There were total 200 patients included in the study. Among them the age groups of 21 – 30 years and 31 – 40 years were mainly suffer from hoarseness. Similarly, among 200 patients 144 (72%) were males whereas 56 (28%) were females with male to female ratio of 2.5:1. The most common cause as per the distribution was acute laryngitis with frequency of 34% followed by acid peptic laryngitis, 25.5%, neoplasms of larynx 12%, whereas tuberculosis of larynx, intubation granuloma, trauma was very few. Conclusion: There was etiological variation in hoarseness ranging from simple laryngitis to malignancies. So it is important not to ignore the hoarseness and precise history, examination and investigations should be done  Bangladesh J of Otorhinolaryngology; October 2018; 24(2): 125-130


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