scholarly journals Adult Onset Epilepsy and History of Childhood Febrile Convulsions: A Retrospective Study

1970 ◽  
Vol 18 (1) ◽  
pp. 54-57
Author(s):  
MH Sardar ◽  
MAR Howlader ◽  
MZ Hossain
Keyword(s):  
Retrospective Study ◽  
Odds Ratio ◽  
Febrile Convulsion ◽  
Adult Onset ◽  
Chi Square ◽  
Febrile Convulsions ◽  
Adult Age ◽  
History Of Childhood ◽  
Chi Square Test ◽  
History Of

Objective: To assess the association between adult -onset epilepsy and history of childhood febrile convulsions (CFC) and determine the types of epilepsy which develop after CFC Design: A retrospective study. Study period: January 2008 to December 2008. Place of study: Epilepsy Clinic of the Department of Neurology of Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka. Materials & Methods: 106 consecutive adult (age>13 years) patients with adult onset epilepsy receiving treatment from Epilepsy Clinic of the Department of Neurology of BSMMU, Dhaka were the sample of this study. Records of these patients were reviewed & the patients & their family members were interviewed to assess the medical history. The data obtained from the records and the interviews formed the basis of this study. Chi-Square test was applied to analysis the data. Results: Results of interview and records of 92 patients were analyzed. Of the 106 patients 14 patients were excluded from this study for the reasons of missing reliable data of the CFC episodes (9), secondary epilepsy due to intracerebral space occupying lesions (ICSOL) (1), history of head injury (1) & meningoencephalitis (3). Thirty one (33.7%) of the remaining ninety two patients had history of CFC in the childhood (71% male, 29% female). Partial epilepsies were significantly associated with history of CFC [Odds Ratio : 3.29; (95% CI 1.30-8.06), (c2=5.49, df=1, p<0.012)] when compared to other epilepsies and epilepsy syndromes. An initial unprovoked simple partial seizure was also significantly associated with a positive history of CFC [Odds Ratio : 8.05; (95% CI 2.88-22.45), (c2=15.86, df=1, p<0.001)]. Conclusion: Partial epilepsies seem to be associated with a history of CFC in childhood. The mechanism & pathophysiology of association between CFC and epilepsy in affected probands requires further investigations. Identification of the basic defect in relation to CFC & epilepsy may have important implication for the prevention of adult- onset epilepsy in patients with history of CFC. But the risk of epilepsy after febrile convulsions is much less than reported in many hospital studies & if febrile convulsion causes brain damage that leads to epilepsy later, this is a rare occurrence. Key words: Generalized epilepsy; partial epilepsy; febrile convulsion; afebrile seizures; genetic. DOI: 10.3329/jdmc.v18i1.6307 J Dhaka Med Coll. 2009; 18(1) : 54-57

scholarly journals Patterns of Adult-Onset Epilepsy Attended in an Epilepsy Clinic in a Specialised Hospital: A Prospective Cross Sectional Study

1970 ◽  
Vol 20 (1) ◽  
pp. 20-24
Author(s):  
MH Sardar ◽  
MAR Howlader ◽  
MU Mallik ◽  
AM Appolo ◽  
MS Islam ◽  
...  
Keyword(s):  
Odds Ratio ◽  
Febrile Convulsion ◽  
Cross Sectional Study ◽  
Adult Onset ◽  
Sectional Study ◽  
Chi Square ◽  
Cross Sectional ◽  
Adult Age ◽  
Chi Square Test ◽  
History Of

A prospective cross sectional study was designed to assess the patterns of adult-onset epilepsy and determine the types of epilepsy which develop after complex febrile convulsion (CFC) and find out the causes of epilepsy, from January to December 2008, in Epilepsy Clinic of the Department of Neurology of Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka. 106 consecutive adult (age>13 years) patients with adult-onset epilepsy receiving treatment from Epilepsy Clinic of the Department of Neurology of BSMMU, Dhaka, were the sample of this study. Records of these patients were reviewed & the patients & their family members were interviewed to assess the medical history. The data obtained from the records and the interviews formed the basis of this study. Chi-Square test was applied to analysis the data. Interviewed results and records of 106 patients were analyzed. Of the 106 patients with adult- onset epilepsy, the epilepsy categories [median age: 20 years, range: 14-46 years] were: generalized epilepsies in 51 (54.06%), partial epilepsies in 45 (47.7%), & undetermined epilepsies in 10 (10.6%) Thirty one (32.86%) of the 106 patients had history of CFC in the childhood (71% male, 29% female). Partial epilepsies were significantly associated with history of CFC [Odds Ratio: 3.29; (95% CI 1.30-8.06), (c2=5.49, df=1, p=0.012)] when compared to other epilepsies and epilepsy syndromes. An initial unprovoked simple partial seizure was also significantly associated with a positive history of CFC [Odds Ratio: 8.05; (95% CI 2.88-22.45), (c2=15.86, df=1, p<0.001)]. Generalized epilepsies are more common than partial epilepsies. Partial epilepsies seem to be associated with a history of CFC in childhood. The mechanism & pathophysiology of association between CFC and epilepsy in affected probands requires further investigations. Identification of the basic defect in relation to CFC & epilepsy may have important implication for the prevention of adult- onset epilepsy in patients with history of CFC. But the risk of epilepsy after febrile convulsions is much less than reported in many hospital studies & if febrile convulsion causes brain damage that leads to later epilepsy, this is a rare occurrence. Keywords: Generalized epilepsy; partial epilepsy; febrile convulsion; afebrile seizures; genetic. DOI: http://dx.doi.org/10.3329/jdmc.v20i1.8567 J Dhaka Med Coll. 2011; 20(1) :20-24

scholarly journals FEBRILE CONVULSIONS IN CHILDREN

2009 ◽  
Vol 16 (04) ◽  
pp. 526-531
Author(s):  
SURRIYA BIBI ◽  
MAQBOOL AHMAD ◽  
AYESHAS AJID
Keyword(s):  
Febrile Illness ◽  
Febrile Convulsion ◽  
Good Prognosis ◽  
Study Data ◽  
Negative Consequences ◽  
Chi Square ◽  
Febrile Convulsions ◽  
Frequency Table ◽  
Chi Square Test ◽  
History Of

O b j e c t i v e s : (i) To know about the knowledge, attitude and practices of parents of children with febrile convulsions, (ii) To provideadequate information of relationship between fever and febrile convulsions and its usual good prognosis. D e s i g n : Descriptive study. S e t t i n g :It was conducted at Pediatric Department of Madina Teaching Hospital Sargodha Road Faisalabad. P e r i o d : Two years period from January2007-2009. M A T E R I A L A N D M E T H O D S : 150 parents and their children with febrile convulsions were included in the study. Diagnosis wasmade on the basis of a history of a convulsion in the child with a febrile illness. Cases were excluded when there was doubt about theoccurrence of convulsions, or if the child previously had convulsions due to any other cause, or if the physical examination or laboratoryparameters suggested any other etiology for the convulsions. LP was done in case of first time febrile fits. A pretested questionnaire comprisingof 12 questions was used for the study. Data was presented through frequency table. Statistical test of significance was Chi-square test. Thedata was analyzed with the help of SPSS computer program EQS 10 N. R e s u l t s : in the study 83 parents (59.3%) could not recognize theconvulsion; 127 parents (90.7%) did not carry out any intervention prior to getting the child to the hospital. 109 (77.9%) parents did not knowthe facts that the convulsion can occur due to fever. For 56 (40%) of the parents every subsequent episode of fever was like a nightmare. Only21 parents (15%) had thermometer at home and 28 (20%) knew the normal range of body temperature. Correct preventive measures wereknown to only 41 (29.2%). C o n c l u s i o n s : Parental fear of fever and febrile convulsion is a major problem with negative consequences affectingdaily family life. The most common immediate effect of the convulsion on the parents was fear of death and insomnia and fear of braindamage.

scholarly journals Prevalence of retinopathy of prematurity: a 3-year retrospective study

2021 ◽  
Vol 9 (11) ◽  
pp. 3352
Author(s):  
Aval S. Patel ◽  
Rishi Mehta
Keyword(s):  
Retrospective Study ◽  
Birth Weight ◽  
Retinopathy Of Prematurity ◽  
Odds Ratio ◽  
Early Screening ◽  
Chi Square ◽  
Background Retinopathy ◽  
Gestation Age ◽  
Chi Square Test ◽  
History Of

Background: Retinopathy of prematurity (ROP) is a vasoproliferative disease of premature infants which leads to permanent blindness. Early screening is needed to diagnose ROP and prevent blindness.Methods: Retrospective study was conducted in 225 neonates from January 2018 to December 2020. All neonates with birth weight <2000 gm and/or gestational age <38 weeks were included. History of oxygen given to neonates and presence of sepsis in neonates was noted. The infant’s pupil were dilated. Fundus examination was done. All the data was entered in MS-Excel 2016 and analyzed by SPSS (version 19). Chi-square test was done to calculate p value.Results: Out of total of 225 neonates, 137 (60.88%) were males and 88 (39.12%) were females. The gestation age of neonates (in weeks) ranged from 25 to 40 (mean: 32.35). The birth weight of neonates (in grams) ranged from 570 to 2500 (mean: 1460). 21 (9.33%) were found to have ROP. The male neonates found with ROP were 16 (11.67%) while females were 5 (5.68%) (p>0.05). Out of 148 neonates who were given oxygen 19 (12.83%) developed ROP (odds ratio: 5.52). Out of 42 neonates who had sepsis, 2 (4.76%) developed ROP (odds ratio: 0.43).Conclusions: The prevalence of ROP was 9.33%. The prevalence is showing a decreasing trend. ROP is not affected by gender. Oxygen given to neonates is associated with greater ROP. But sepsis in neonates is not associated with development of ROP.

scholarly journals Prognostic significance of peritoneal cytology in low-risk endometrial cancer: comparison of laparoscopic surgery and laparotomy

2021 ◽  
Author(s):  
Satoe Fujiwara ◽  
Ruri Nishie ◽  
Shoko Ueda ◽  
Syunsuke Miyamoto ◽  
Shinichi Terada ◽  
...  
Keyword(s):  
Endometrial Cancer ◽  
Laparoscopic Surgery ◽  
Retrospective Study ◽  
Prognostic Significance ◽  
Low Risk ◽  
Peritoneal Cytology ◽  
Chi Square ◽  
Significant Difference ◽  
Chi Square Test ◽  
Positive Peritoneal Cytology

Abstract Background There is uncertainty surrounding the prognostic value of peritoneal cytology in low-risk endometrial cancer, especially in laparoscopic surgery. The objective of this retrospective study is to determine the prognostic significance of positive peritoneal cytology among patients with low-risk endometrial cancer and to compare it between laparoscopic surgery and conventional laparotomy. Methods From August 2008 to December 2019, all cases of pathologically confirmed stage IA grade 1 or 2 endometrial cancer were reviewed at Osaka Medical College. Statistical analyses used the Chi-square test and the Kaplan–Meier log rank. Results A total of 478 patients were identified: 438 with negative peritoneal cytology (232 who underwent laparotomy and 206 who undertook laparoscopic surgery) and 40 with positive peritoneal cytology (20 who underwent laparotomy and 20 who received laparoscopic surgery). Survival was significantly worse among patients with positive peritoneal cytology compared to patients with negative peritoneal cytology. However, there was no significant difference among patients with negative or positive peritoneal cytology between laparoscopic surgery and laparotomy. Conclusion This retrospective study suggests that, while peritoneal cytology is an independent risk factor in patients with low-risk endometrial cancer, laparoscopic surgery does not influence the survival outcome when compared to laparotomy.

scholarly journals Microbial Colonization and their Relation with Potential Cofactors in Patients with Denture Stomatitis

2012 ◽  
Vol 13 (4) ◽  
pp. 456-459 ◽  
Author(s):  
Bhushan Arun Jawale ◽  
Rahul Redasani ◽  
Lalit Chaudhari ◽  
Narendra Chopde ◽  
Amol Pharande ◽  
...  
Keyword(s):  
Mucous Membrane ◽  
Microbial Colonization ◽  
Microbiological Analysis ◽  
Chi Square ◽  
Carbohydrate Ingestion ◽  
Denture Stomatitis ◽  
Dietary History ◽  
Salivary Ph ◽  
Chi Square Test ◽  
History Of

ABSTRACT Aim To determine microbial prevalence in the mucous membrane and prosthesis of denture wearers with and without denture stomatitis and to study its relationship with potential clinical cofactors. Materials and methods Saliva was collected from 200 patients (100 female and 100 male) wearing dental prosthesis for measurement of pH. Oral samples of the mucous membrane and of dentures were taken with sterile swab for microbiological analysis. Medical and dietary history of the subjects was recorded. Chi-square test and analysis of varience were used for statistical analysis. Results Diabetes, hypertension and high carbohydrate ingestion was observed in majority of patients. The pH average in saliva was of 5.1. The presence of C. albicans, S. aureus and S. mutans in the mucous membrane was of 55.4, 56.4 and 63.6% respectively. C. albicans was isolated in 69.7% from the prosthesis, whereas S. aureus and S. mutans were isolated in 45.3%. The isolation of C.albicans was more frequent in patients with deture stomatitis. Conclusion C. albicans, S. aureus and S. mutans frequently colonize the oral mucous of denture wearers. This is more frequently observed in patients with denture stomatitis. Clinical significance Denture stomatitis is associated to Candida albicans, different bacteria and other cofactors, such as salivary pH, carbohydrate ingestion, systemic illnesses and medication. How to cite this article Chopde N, Jawale B, Pharande A, Chaudhari L, Hiremath V, Redasani R. Microbial Colonization and their Relation with Potential Cofactors in Patients with Denture Stomatitis. J Contemp Dent Pract 2012;13(4):456-459.

scholarly journals Prevalence and risk factors of apical periodontitis in endodontically treated teeth in a selected population of Brazilian adults

2008 ◽  
Vol 19 (1) ◽  
pp. 34-39 ◽  
Author(s):  
Carlos Estrela ◽  
Cláudio Rodrigues Leles ◽  
Augusto César Braz Hollanda ◽  
Marcelo Sampaio Moura ◽  
Jesus Djalma Pécora
Keyword(s):  
Risk Factors ◽  
Confidence Intervals ◽  
Odds Ratio ◽  
Apical Periodontitis ◽  
Endodontic Treatment ◽  
Technical Quality ◽  
Endodontically Treated Teeth ◽  
Chi Square ◽  
Chi Square Test

The aim of this study was to assess the prevalence and risk factors of apical periodontitis in endodontically treated teeth in a selected population of Brazilian adults. A total of 1,372 periapical radiographs of endodontically treated teeth were analyzed based on the quality of root filling, status of coronal restoration and presence of posts associated with apical periodontitis (AP). Data were analyzed statistically using odds ratio, confidence intervals and chi-square test. The prevalence of AP with adequate endodontic treatment was low (16.5%). This percentage dropped to 12.1% in cases with adequate root filling and adequate coronal restoration. Teeth with adequate endodontic treatment and poor coronal restoration had an AP prevalence of 27.9%. AP increased to 71.7% in teeth with poor endodontic treatment associated with poor coronal restoration. When poor endodontic treatment was combined with adequate coronal restoration, AP prevalence was 61.8%. The prevalence of AP was low when associated with high technical quality of root canal treatment. Poor coronal restoration increased the risk of AP even when endodontic treatment was adequate (OR=2.80; 95%CI=1.87-4.22). The presence of intracanal posts had no influence on AP prevalence.

Vicinity of Schools, But Not of Residences, Seems to Regulate Physical and Sports Activities of 13-Year-Old Teenagers in a South European Setting

2017 ◽  
Vol 14 (1) ◽  
pp. 67-75 ◽  
Author(s):  
Alexandre Magalhães ◽  
Elisabete Ramos ◽  
Maria Fátima Pina
Keyword(s):  
Physical Activity ◽  
Odds Ratio ◽  
Parental Education ◽  
Sports Participation ◽  
Green Spaces ◽  
Chi Square ◽  
Physically Active ◽  
Urban Green Spaces ◽  
Chi Square Test ◽  
Sports Activities

Background:Proximity to urban green spaces (UGS) and open sports spaces (OSS) benefits health, promotes physical activity (PA) and sports practice (SP).Objective:Analyze the association between PA or SP according to distances between UGS or OSS and teenagers’ residences or schools.Methods:We evaluated 1333 (53.9% girls) teenagers (13 years old) living and studying in Porto, Portugal (EPITeen cohort). PA was classified as light or moderate/vigorous. Distances were the shortest routes from residences or schools to UGS/OSS, and classified in ≤250 m; >250 m to ≤500 m; >500 m to ≤750 m; >750 m. Chi-square test and chi-square for trends were used to compare proportions; associations were measured using logistic regression, through odds ratio and 95% confidence intervals, adjusting to BMI and parental education.Results:Regarding vicinity’ of schools, the prevalence of moderate/vigorous PA among boys, decreases as distances to OSS increases. For girls, the prevalence of sports decreases as distances to UGS increase. For boys, we found an association between moderate/vigorous PA and proximity to OSS in the vicinity of schools: considering ≤250 m as reference, the odds of moderate/vigorous PA is 0.20 (0.06–0.63) for >250 m to ≤500 m; 0.21 (0.07–0.61) for >500 m to ≤750 m and 0.19 (0.06–0.58) for >750 m.Conclusion:Vicinities of schools seem to influence teenagers to be more physically active and increase sports participation.

Abstract TP207: Sex Differences in Cardiovascular Risk Profiles of Patients with Diabetes in the Greater Cincinnati/ Northern Kentucky Stroke Study

Stroke ◽  
2017 ◽  
Vol 48 (suppl_1) ◽  
Author(s):  
Tracy E Madsen ◽  
Jane C Khoury ◽  
Kathleen Alwell ◽  
Charles J Moomaw ◽  
Stacie L Demel ◽  
...  
Keyword(s):  
Cardiovascular Risk ◽  
Stroke Risk ◽  
Negative Impact ◽  
Age Difference ◽  
Risk Profiles ◽  
Chi Square ◽  
Adult Age ◽  
Stroke Study ◽  
Patients With Diabetes ◽  
History Of

Introduction: Diabetes mellitus (DM) carries a greater stroke risk for females than males, possibly because of a difference in cardiovascular risk profiles between females and males with DM. Our aim was to compare the sex-specific risk factor profiles for patients with DM with those without DM among patients with acute ischemic stroke (AIS) in the Greater Cincinnati/ Northern Kentucky Stroke Study (GCNKSS). Methods: The GCNKSS ascertained cases of AIS in 2005 and 2010 among adult (age ≥20 years) residents of a biracial population of 1.3 million. Past and current stroke risk factors, obtained via chart review, were compared between those with and without DM using chi-square to examine bivariate differences and multiple logistic regression to examine sex-specific profiles. P < 0.05 was considered statistically significant. Results: There were 3515 patients with incident AIS; 1919 (55%) were female, 697 (20%) were black, and 1146 (33%) had DM. A lower proportion of females with DM were over 65 years old compared with those without DM. The proportion of males >65 with DM was not significantly different from that of males without DM. Among both females and males with DM, significantly more were Black, obese, and had histories of hypertension, high cholesterol, CAD and myocardial infarction compared to those without DM. In sex-specific adjusted analyses, women with DM were significantly less likely to be over 65 and more likely to have CAD than women without DM, whereas age and CAD were not significant factors in differentiating the profiles of men with and without DM. Conclusions: The result that females had their strokes at a younger age if they had a history of DM, and that no such age difference existed in males, suggests that DM is more severe and has a greater negative impact on females than males. As opposed to males, females with DM were also more likely to have CAD compared to those without DM, consistent with a possible sex difference in the association between DM and vascular disease.

HUBUNGAN TINGKAT PENGETAHUAN MENGENAI DIET HIPERTENSI TERHADAP KEJADIAN HIPERTENSI PADA LANSIA DI PUSKESMAS BALOI PERMAI BATAM KOTA

2020 ◽  
Vol 9 (1) ◽  
pp. 50-60
Author(s):  
Brain Guntoro ◽  
Kasih Purwati
Keyword(s):  
Public Health ◽  
Health Center ◽  
The Elderly ◽  
P Value ◽  
Chi Square ◽  
Cross Sectional ◽  
Public Health Center ◽  
Chi Square Test ◽  
History Of ◽  
Level Of Knowledge

Hypertension is one of the number one causes of death and disability in the world. Hypertension contributes nearly 9.4 million deaths from cardiovascular disease each year. Hypertension can cause undesirable effects, it needs good handling, one of them is by doing a hypertension diet. To carry out a hypertension diet requires knowledge, lack of knowledge can increase risk factors for hypertension. This study aims to determine the relationship of the level of knowledge about hypertension diet to the incidence of hypertension in the elderly at the Baloi Permai Public Health Center Batam City. This research method is an analytic observational with a cross-sectional approach conducted at the Baloi Permai Public Health Center Batam City 2018. Sampling technique is a total sampling with a sample of 64 people in 2018 determined by inclusion and exclusion criteria. The results of the study were analyzed with frequency distribution and then tested with the Chi-square test. Based on the results of this study indicate that of the 64 respondents found elderly who have a good level of knowledge are 41 people (64.1%), 48 people (75.0%) have an age range between 60-70 years. 27 people (42.2%) elderly have the last high school education and 40 people (62.5%) have jobs as entrepreneurs. Elderly people who have normal blood pressure are 40 people (62.5%), and those affected by hypertension are 24 people (37.5%). The elderly who have a family history of hypertension is 21 people (32.8%) and those who do not have a history of hypertension are 43 people (67.2%). Chi-Square Test analysis results show the significance value p = 0.009. This number is significant because the p-value is smaller than the significance level (α) ≤ 5% (0.05), so H0 is rejected and Ha is accepted. Therefore it can be concluded that there is a significant relationship about the level of knowledge about the hypertension diet to the incidence of hypertension in the elderly. From the results of this study it was concluded that there was a relationship between the level of knowledge about the hypertension diet and the incidence of hypertension in the elderly at the Baloi Permai Public Health Center Batam City in 2016.

scholarly journals Kondisi Kebersihan Lingkungan Berhubungan dengan Risiko Penularan Kasus Leptospirosis di Area Pasar Tradisional

2020 ◽  
pp. 199-208
Author(s):  
Dyah Widiastuti ◽  
Dwi Priyanto
Keyword(s):  
Cross Sectional Study ◽  
Market Area ◽  
Chi Square ◽  
Pathogenic Leptospira ◽  
Cross Sectional ◽  
Chi Square Test ◽  
History Of ◽  
Polymerase Chain ◽  
Gathering Place ◽  
The Relationship

Leptospirosis is associated with occupations which exposed workers to contaminated environments. The risk of leptospirosis exposure in the market as a gathering place for many people needs to be assessed, to obtain the basis for decision making to anticipate leptospirosis transmission. This study aimed to determine the relationship between market environmental conditions including market sanitation conditions, the level of rat density and the presence of leptospira-positive rats  toward the history of leptospirosis exposure among market workers (traders and janitors). A cross sectional study conducted in 35 markets in Banjarnegara and 175 market workers randomly selected. Blood samples analysed using ELISA against 40 Kda pathogenic Leptospira protein. Rat trapping  conducted in each market for two days with 100 traps. The caught mice examined with Polymerase Chain Reaction (PCR) to detect the presence of Leptospira bacteria in their kidneys. Leptospirosis exposure was spread in 17 markets in Banjarnegara. The PCR examination showed that the pathogenic Leptospira infected rats were spread in four markets in Banjarnegara. Chi square test showed that the hygene condition in market area was significantly associated with the leptospirosis exposure. Markets workers (traders and janitors) were at risk for leptospirosis proved by high seroprevalence of leptospirosis in this study.

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