scholarly journals Prevalence of retinopathy of prematurity: a 3-year retrospective study

Author(s):  
Aval S. Patel ◽  
Rishi Mehta

Background: Retinopathy of prematurity (ROP) is a vasoproliferative disease of premature infants which leads to permanent blindness. Early screening is needed to diagnose ROP and prevent blindness.Methods: Retrospective study was conducted in 225 neonates from January 2018 to December 2020. All neonates with birth weight <2000 gm and/or gestational age <38 weeks were included. History of oxygen given to neonates and presence of sepsis in neonates was noted. The infant’s pupil were dilated. Fundus examination was done. All the data was entered in MS-Excel 2016 and analyzed by SPSS (version 19). Chi-square test was done to calculate p value.Results: Out of total of 225 neonates, 137 (60.88%) were males and 88 (39.12%) were females. The gestation age of neonates (in weeks) ranged from 25 to 40 (mean: 32.35). The birth weight of neonates (in grams) ranged from 570 to 2500 (mean: 1460). 21 (9.33%) were found to have ROP. The male neonates found with ROP were 16 (11.67%) while females were 5 (5.68%) (p>0.05). Out of 148 neonates who were given oxygen 19 (12.83%) developed ROP (odds ratio: 5.52). Out of 42 neonates who had sepsis, 2 (4.76%) developed ROP (odds ratio: 0.43).Conclusions: The prevalence of ROP was 9.33%. The prevalence is showing a decreasing trend. ROP is not affected by gender. Oxygen given to neonates is associated with greater ROP. But sepsis in neonates is not associated with development of ROP.

1970 ◽  
Vol 18 (1) ◽  
pp. 54-57
Author(s):  
MH Sardar ◽  
MAR Howlader ◽  
MZ Hossain

Objective: To assess the association between adult -onset epilepsy and history of childhood febrile convulsions (CFC) and determine the types of epilepsy which develop after CFC Design: A retrospective study. Study period: January 2008 to December 2008. Place of study: Epilepsy Clinic of the Department of Neurology of Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka. Materials & Methods: 106 consecutive adult (age>13 years) patients with adult onset epilepsy receiving treatment from Epilepsy Clinic of the Department of Neurology of BSMMU, Dhaka were the sample of this study. Records of these patients were reviewed & the patients & their family members were interviewed to assess the medical history. The data obtained from the records and the interviews formed the basis of this study. Chi-Square test was applied to analysis the data. Results: Results of interview and records of 92 patients were analyzed. Of the 106 patients 14 patients were excluded from this study for the reasons of missing reliable data of the CFC episodes (9), secondary epilepsy due to intracerebral space occupying lesions (ICSOL) (1), history of head injury (1) & meningoencephalitis (3). Thirty one (33.7%) of the remaining ninety two patients had history of CFC in the childhood (71% male, 29% female). Partial epilepsies were significantly associated with history of CFC [Odds Ratio : 3.29; (95% CI 1.30-8.06), (c2=5.49, df=1, p<0.012)] when compared to other epilepsies and epilepsy syndromes. An initial unprovoked simple partial seizure was also significantly associated with a positive history of CFC [Odds Ratio : 8.05; (95% CI 2.88-22.45), (c2=15.86, df=1, p<0.001)]. Conclusion: Partial epilepsies seem to be associated with a history of CFC in childhood. The mechanism & pathophysiology of association between CFC and epilepsy in affected probands requires further investigations. Identification of the basic defect in relation to CFC & epilepsy may have important implication for the prevention of adult- onset epilepsy in patients with history of CFC. But the risk of epilepsy after febrile convulsions is much less than reported in many hospital studies & if febrile convulsion causes brain damage that leads to epilepsy later, this is a rare occurrence. Key words: Generalized epilepsy; partial epilepsy; febrile convulsion; afebrile seizures; genetic. DOI: 10.3329/jdmc.v18i1.6307 J Dhaka Med Coll. 2009; 18(1) : 54-57


PUINOVAKESMAS ◽  
2020 ◽  
Vol 1 (2) ◽  
pp. 103-110
Author(s):  
Heni Puji Wahyuningsih ◽  
Indah Ajeng Pramesti ◽  
Endah Marianingsih Theresia

Low Born Weigh (LBW) is a baby with a birth weight <2500 grams. LBW babies are weak in fine motor skills. If toddlers' developmental disorders are not detected early it will affect the quality of life, showed the prevalence of LBW by 5.52%. The prevalence of LBW infants in Bantul Regency from 2014 to 2018 has increased. The highest LBW cases were in the Pleret Puskesmas which reached 6.23%. The high prevalence of LBW in Pleret District has made researchers interested in researching the relationship of LBW history with the development of toddlers aged 1-3 years. The purpose of this research is to find out the influence of LBW history on the development of toddlers aged 1-3 years. This type of research is an observational analytic study with a retrospective cohort design. The sample in this study is toddlers aged 1-3 years in the district of Pleret. The independent variables of this study were the birth weight of infants and the dependent variable of development of infants aged 1-3 years. Statistical tests use the Chi-square test and relative risk. This research shows that as many as 31% of children under five with a history of LBW had inappropriate development status. The chi-square test showed a p-value of 0.016 (<0.05) which meant that there was a significant relationship between LBW history and the developmental status of toddlers. Obtained RR value of 1,250 (> 1,00), shows that toddlers with a history of LBW have a risk of experiencing developmental disorders 1.25 times greater than toddlers with normal weight history. The conclusion of this research is a there is a significant relationship between LBW history and the development of toddlers aged 1-3 years. Toddlers with an LBW history have a greater risk of developing developmental disorders compared to toddlers with normal weight history.


2020 ◽  
Vol 2 (1) ◽  
pp. 22-26
Author(s):  
Anjar Astuti ◽  
Yanik Muyassaroh ◽  
Murti Ani

One of the nutritional problems faced by children under five in the world, especially in developing countries is stunting. The problem of stunting in infants can have an impact on intellectual decline, increase the risk of non-communicable diseases, giving birth to babies with low birth weight and the risk of degenerative diseases in the future. So it is necessary to take preventative measures in order to reduce the stunting prevalence rate that is increasing every year. The purpose of this study: to determine the relationship between maternal pregnancy history and the history of the baby's birth to the incidence of stunting in infants. Research methods: using a retrospective cohort design with a sample of 85 mothers who have stunting toddlers. Results: Analysis of data using the chi square test of birth length (p = 0,000 0.05) has a relationship with the incidence of stunting while anemia during pregnancy (p = 0.212 0.05), chronic energy shortages during pregnancy (p = 0.837 0.05) and low birth weight (p = 0.297 0.05) had no relationship with the incidence of stunting. Conclusion: there was no significant relationship between maternal pregnancy history (Anemia and KEK), history of birth of the baby (LBW) and nutritional care patterns (accuracy of breastfeeding MP) with the incidence of stunting in infants. There is a significant relationship between the history of the birth of a baby (length of body birth) can cause stunting in infants. Suggestion: the results of this study can be taken into consideration to conduct early intervention appropriately to reduce the stunting rate in Blora Regency. Keywords: History of maternal pregnancy, history of baby's birth, toddler stunting. 


2016 ◽  
Vol 12 (2) ◽  
pp. 175 ◽  
Author(s):  
Fitri Nur Dini ◽  
Pudji Andayani ◽  
Lena Rosida

Abstract: Neonatal sepsis is a clinical syndrome characterized by symptoms of bacteremia and systemic signs and positive blood cultures showed that during the first month of life. Prematurity and postmaturity risk of morbidity and mortality are high on the gestation age for the occurrence of neonatal sepsis. This study aims to determine the relationship between gestational age and the incidence of neonatal sepsis in Ulin Hospital Banjarmasin. The design of this study using cross sectional study with retrospective approach. The way the sampling is the purposive sampling were obtained from medical records of patients, then performed statistical analysis using chi-square test with 95%. The number of samples that fulfilled the criteria inclusion in this study as many as 246 cases. The incidence of neonatal sepsis is more common in infants born at 37-42 weeks gestation as many as 25 cases (59.52%). The data not neonatal sepsis who were born with a gestational age <37 weeks or> 42 weeks gained as many as 20 cases (9.80%) and 37-42 weeks gestation obtained as many as 184 cases (90.20%). Chi-square test showed that there is a relationship between gestational age and the incidence of neonatal sepsis in Ulin Hospital Banjarmasin (p = 0.000) with an odds ratio (OR) 6.256. It is concluded that there is a relationship of gestation age and the incidence of neonatal sepsis (p <0.05) in hospitals Ulin Banjarmasin period June 2014-June 2015 with OR 6.256. Keywords: gestational age, sepsis, neonatal Abstrak: Sepsis neonatorum merupakan suatu sindrom klinis bakteremia yang ditandai dengan gejala dan tanda sistemik serta menunjukkan kultur darah positif yang terjadi pada bulan pertama kehidupan. Prematuritas dan posmaturitas memiliki risiko kesakitan dan kematian yang tinggi pada masa gestasi untuk terjadinya sepsis neonatorum. Penelitian ini bertujuan untuk mengetahui hubungan antara masa gestasi dan kejadian sepsis neonatorum di RSUD Ulin Banjarmasin. Rancangan penelitian ini menggunakan cross sectional study dengan pendekatan retrospektif. Cara pengambilan sampel yaitu dengan purposive sampling yang diperoleh dari data rekam medis pasien, kemudian dilakukan analisis statistik menggunakan uji chi-square dengan kepercayaan 95%. Jumlah sampel yang memenuhi kriteria inklusi dalam penelitian ini sebanyak 246 kasus. Kejadian sepsis neonatorum lebih banyak dijumpai pada bayi yang lahir dengan masa gestasi 37-42 minggu yaitu sebanyak 25 kasus (59,52%). Data neonatus tidak sepsis yang lahir dengan masa gestasi <37 minggu atau >42 minggu didapatkan sebanyak 20 kasus (9,80%) dan masa gestasi 37-42 minggu didapatkan sebanyak 184 kasus (90,20%). Uji chi square menunjukkan bahwa terdapat hubungan antara masa gestasi dan kejadian sepsis neonatorum di RSUD Ulin Banjarmasin (p=0,000) dengan odds ratio (OR) 6,256. Kesimpulan penelitian ini adalah terdapat hubungan masa gestasi dan kejadian sepsis neonatorum (p<0,05) di RSUD Ulin Banjarmasin periode Juni 2014-Juni 2015 dengan OR 6,256. Kata-kata kunci: masa gestasi, sepsis, neonatus


2014 ◽  
Vol 132 (2) ◽  
pp. 85-91 ◽  
Author(s):  
Eduardo Gonçalves ◽  
Luciano Sólia Násser ◽  
Daniella Reis Martelli ◽  
Isadora Ramos Alkmim ◽  
Thalita Veloso Mourão ◽  
...  

CONTEXT AND OBJECTIVE: Retinopathy of prematurity (ROP) is a known cause of blindness in which diagnosis and timely treatment can prevent serious harm to the child. This study aimed to evaluate the incidence of ROP and its association with known risk factors. DESIGN AND SETTING: Longitudinal incidence study in the neonatal intensive care unit (NICU) of Universidade Estadual de Montes Claros. METHODS: Newborns admitted to the NICU with gestational age less than 32 weeks and/or birth weight less than 1,500 grams, were followed up over a two-year period. The assessment and diagnosis of ROP were defined in accordance with a national protocol. The chi-square test or Fisher's exact test were used to determine associations between independent variables and ROP. Analysis on the independent effect of the variables on the results was performed using multiple logistic regression. RESULTS: The incidence of ROP was 44.5% (95% confidence interval, CI = 35.6-46.1) in the study population. The risk factors associated with the risk of developing the disease were: birth weight less than 1,000 grams (odds ratio, OR = 4.14; 95% CI = 1.34-12.77); gestational age less than 30 weeks (OR = 6.69; 95% CI = 2.10-21.31); use of blood derivatives (OR = 4.14; 95% CI = 2.99-8.99); and presence of sepsis (OR = 1.99; 95% CI = 1.45-2.40). CONCLUSIONS: The incidence of ROP was higher than that found in the literature. The main risk factors were related to extreme prematurity. CONTEXTO E OBJETIVO: A retinopatia da prematuridade (ROP) é causa conhecida de cegueira e diagnóstico e tratamento oportunos podem evitar graves danos à criança. Este estudo objetivou avaliar a incidência da ROP e sua associação com fatores de risco conhecidos.


2018 ◽  
Vol 15 (2) ◽  
pp. 45
Author(s):  
Apri Sulistianingsih ◽  
Rita Sari

Background: Stunting cases in infants in Indonesia continue to be a maternal and child health problem. Stunting cases in Pesawaran District increase every year. Some of the factors that influence the incidence of stunting in children include the history of exclusive breastfeeding and low birth weight (LBW) babies.Objective: This study aims to determine the effect of exclusive breastfeeding and birth weight on stunting in children 2-5 years cases in Pesawaran District.Method: This research used observational analytics with a cross-sectional approach. This research was conducted in March-May 2017 in 12 Puskesmas on Pesawaran Lampung District. The number of samples was 385 samples. The variables studied in this study were the incidence of stunting, history of LBW and history of exclusive breastfeeding. Analysis and present data using the Chi-Square test and multiple logistic regression.Results: Children with a history of LBW (OR=12.30; 95% CI:3.663-41.299) and exclusive breastfeeding history (OR=0.122; 95% CI:0.075-0.199) were significantly associated with the incidence of stunting. The multivariate analysis explained the history of exclusive breastfeeding with OR=0.108 (CI 95%: 0.065-0.180) and birth weight with OR=17.063 (CI 95%: 4.892-59.511).Conclusion: Children with exclusively breastfeeding 9.3 times less risk for stunting than children non-exclusive breastfeeding or exclusive breastfeeding provides a protective effect against stunting in toddlers. Children with an LBW history had a risk of 17.063 times greater for stunting than children with normal birth weight.


1970 ◽  
Vol 20 (1) ◽  
pp. 20-24
Author(s):  
MH Sardar ◽  
MAR Howlader ◽  
MU Mallik ◽  
AM Appolo ◽  
MS Islam ◽  
...  

A prospective cross sectional study was designed to assess the patterns of adult-onset epilepsy and determine the types of epilepsy which develop after complex febrile convulsion (CFC) and find out the causes of epilepsy, from January to December 2008, in Epilepsy Clinic of the Department of Neurology of Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka. 106 consecutive adult (age>13 years) patients with adult-onset epilepsy receiving treatment from Epilepsy Clinic of the Department of Neurology of BSMMU, Dhaka, were the sample of this study. Records of these patients were reviewed & the patients & their family members were interviewed to assess the medical history. The data obtained from the records and the interviews formed the basis of this study. Chi-Square test was applied to analysis the data. Interviewed results and records of 106 patients were analyzed. Of the 106 patients with adult- onset epilepsy, the epilepsy categories [median age: 20 years, range: 14-46 years] were: generalized epilepsies in 51 (54.06%), partial epilepsies in 45 (47.7%), & undetermined epilepsies in 10 (10.6%) Thirty one (32.86%) of the 106 patients had history of CFC in the childhood (71% male, 29% female). Partial epilepsies were significantly associated with history of CFC [Odds Ratio: 3.29; (95% CI 1.30-8.06), (c2=5.49, df=1, p=0.012)] when compared to other epilepsies and epilepsy syndromes. An initial unprovoked simple partial seizure was also significantly associated with a positive history of CFC [Odds Ratio: 8.05; (95% CI 2.88-22.45), (c2=15.86, df=1, p<0.001)]. Generalized epilepsies are more common than partial epilepsies. Partial epilepsies seem to be associated with a history of CFC in childhood. The mechanism & pathophysiology of association between CFC and epilepsy in affected probands requires further investigations. Identification of the basic defect in relation to CFC & epilepsy may have important implication for the prevention of adult- onset epilepsy in patients with history of CFC. But the risk of epilepsy after febrile convulsions is much less than reported in many hospital studies & if febrile convulsion causes brain damage that leads to later epilepsy, this is a rare occurrence. Keywords: Generalized epilepsy; partial epilepsy; febrile convulsion; afebrile seizures; genetic. DOI: http://dx.doi.org/10.3329/jdmc.v20i1.8567 J Dhaka Med Coll. 2011; 20(1) :20-24


2017 ◽  
Vol 19 (2) ◽  
pp. 95
Author(s):  
Hetriana Leksananingsih ◽  
Slamet Iskandar ◽  
Tri Siswati

Background: Riskesdas in 2013 showed that Yogyakarta (DIY) had a prevalence of stunted new kid in school is less than the national average, which is 14.9% (MOH, 2013). Stunted or short, is a linear growth retardation has been widely used as an indicator to measure the nutritional status of individuals and community groups. Stunted can be influenced by several factors: birth weight, birth length match and genetic factors. Objective: To determine the weight, length of low birth weight and genetic factors as predictors of the occurrence of stunted on elementary school children. Methods: The study was a case control analytic. Research sites in SD Muhammadiyah Ngijon 1 Subdistrict Moyudan. The study was conducted in May and June 2015. The subjects were school children grade 1 to grade 5 the number of cases as many as 47 children and 94 control children. With the inclusion criteria of research subjects willing to become respondents, was present at the time of the study, they have a father and mother, and exclusion criteria have no data BB and PB birth, can not stand upright. The research variables are BBL, PBL, genetic factors and TB / U at this time. Data were analyzed by chi-square test and Odd Ratio (OR) calculation. Results: In case group as much as 91.5% of normal birth weight and length of 80.9% of normal birth weight, most of the height of a normal mother and father as many as 85.1%. In the control group as much as 78.7% of normal birth weight and 61.7% were born normal body length, height mostly normal mom and dad that 96.7% of women and 90.4% normal normal father. Statistical test result is no significant correlation between height mothers with stunted incidence in school children, and the results of chi-square test P = 0.026 with value Odd Ratio (OR) of 3.9 and a range of values from 1.091 to 14.214 Cl95%. Conclusion: High maternal body of mothers can be used as predictors of the occurrence of stunted school children and mothers with stunted nutritional status have 3.9 times the risk of having children with stunted nutritional status.


Author(s):  
Satoe Fujiwara ◽  
Ruri Nishie ◽  
Shoko Ueda ◽  
Syunsuke Miyamoto ◽  
Shinichi Terada ◽  
...  

Abstract Background There is uncertainty surrounding the prognostic value of peritoneal cytology in low-risk endometrial cancer, especially in laparoscopic surgery. The objective of this retrospective study is to determine the prognostic significance of positive peritoneal cytology among patients with low-risk endometrial cancer and to compare it between laparoscopic surgery and conventional laparotomy. Methods From August 2008 to December 2019, all cases of pathologically confirmed stage IA grade 1 or 2 endometrial cancer were reviewed at Osaka Medical College. Statistical analyses used the Chi-square test and the Kaplan–Meier log rank. Results A total of 478 patients were identified: 438 with negative peritoneal cytology (232 who underwent laparotomy and 206 who undertook laparoscopic surgery) and 40 with positive peritoneal cytology (20 who underwent laparotomy and 20 who received laparoscopic surgery). Survival was significantly worse among patients with positive peritoneal cytology compared to patients with negative peritoneal cytology. However, there was no significant difference among patients with negative or positive peritoneal cytology between laparoscopic surgery and laparotomy. Conclusion This retrospective study suggests that, while peritoneal cytology is an independent risk factor in patients with low-risk endometrial cancer, laparoscopic surgery does not influence the survival outcome when compared to laparotomy.


2012 ◽  
Vol 13 (4) ◽  
pp. 456-459 ◽  
Author(s):  
Bhushan Arun Jawale ◽  
Rahul Redasani ◽  
Lalit Chaudhari ◽  
Narendra Chopde ◽  
Amol Pharande ◽  
...  

ABSTRACT Aim To determine microbial prevalence in the mucous membrane and prosthesis of denture wearers with and without denture stomatitis and to study its relationship with potential clinical cofactors. Materials and methods Saliva was collected from 200 patients (100 female and 100 male) wearing dental prosthesis for measurement of pH. Oral samples of the mucous membrane and of dentures were taken with sterile swab for microbiological analysis. Medical and dietary history of the subjects was recorded. Chi-square test and analysis of varience were used for statistical analysis. Results Diabetes, hypertension and high carbohydrate ingestion was observed in majority of patients. The pH average in saliva was of 5.1. The presence of C. albicans, S. aureus and S. mutans in the mucous membrane was of 55.4, 56.4 and 63.6% respectively. C. albicans was isolated in 69.7% from the prosthesis, whereas S. aureus and S. mutans were isolated in 45.3%. The isolation of C.albicans was more frequent in patients with deture stomatitis. Conclusion C. albicans, S. aureus and S. mutans frequently colonize the oral mucous of denture wearers. This is more frequently observed in patients with denture stomatitis. Clinical significance Denture stomatitis is associated to Candida albicans, different bacteria and other cofactors, such as salivary pH, carbohydrate ingestion, systemic illnesses and medication. How to cite this article Chopde N, Jawale B, Pharande A, Chaudhari L, Hiremath V, Redasani R. Microbial Colonization and their Relation with Potential Cofactors in Patients with Denture Stomatitis. J Contemp Dent Pract 2012;13(4):456-459.


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