scholarly journals Causes of Vascularised Corneal Opacity Those Were Treated by Corneal Grafting

2017 ◽  
Vol 29 (1) ◽  
pp. 23-25
Author(s):  
Md Shariful Islam Bhuiya

One of the leading causes of blindness is corneal disorder. By keratoplasty we can restore vision of those patients to some extent and many surgeons are performing keratoplasty on vascularised cornea. Present study was done to evaluate its outcome. Patients (5-70 yrs) were recruited from eye ward of Dhaka Medical College Hospital from January, 2007 to December, 2007. Patients were selected on some criteria. Total 33 cases were evaluated before and after operation. This study was carried out to know pattern of blindness and to obtain the causes of corneal vascularisation and results of keratoplasty on these patients. Among 2 types of grafting all our patients were undergone penetrating keratoplasty. Male predominance (57.50) was marked as male are more prone to corneal diseases and trauma. Considering age group nobody is immune from corneal disease but children and young persons are more vulnerable. Socio-economic status of our maximum patients are middle-class or poor class. We got a rough idea about the causes leading to vascularisation of cornea. Amongst them; trauma, corneal ulcer, chemical injury and under nutrition are noted in our study. Out of 33 healthy grafts, visual improvement occurred in 24 cases. Visual results of grafting on vascularised corneas are variable. Our study concludes that trauma and corneal ulcer are the leading causes of corneal opacity which need penetrating keratoplasty. Whatever the cause of corneal vascularisation, prognosis of keratoplasty on such cases is not disappointing. Rather keratoplasty done on early notified corneal opacity with superficial vascularisation gives satisfactory results.Medicine Today 2017 Vol.29(1): 23-25

2017 ◽  
Vol 28 (2) ◽  
pp. 69-71
Author(s):  
Md Shariful Islam Bhuiya

One of the leading causes of blindness is corneal disorder. By keratoplasty we can restore vision of those patients to some extent and many surgeons are performing keratoplasty on vascularised cornea. Present study was done to evaluate its outcome. Patients (5-70 yrs) were recruited from eye ward of Dhaka Medical College Hospital from January, 2007 to December, 2007. Patients were selected on some criteria. Total 33 cases were evaluated before and after operation. This study was carried out to know pattern of blindness and to obtain the causes of corneal vascularisation and results of keratoplasty on these patients. Among 2 types of grafting all our patients were undergone penetrating keratoplasty. Male predominance (57.50) was marked as male are more prone to corneal diseases and trauma. Considering age group nobody is immune from corneal disease but children and young persons are more vulnerable. Socio-economic status of our maximum patients are middle-class or poor class. We got a rough idea about the causes leading to vascularisation of cornea. Amongst them; trauma, corneal ulcer, chemical injury and under nutrition are noted in our study. Out of 33 healthy grafts, visual improvement occurred in 24 cases. Visual results of grafting on vascularised corneas are variable. Our study concludes that trauma and corneal ulcer are the leading causes of corneal opacity which need penetrating keratoplasty. Whatever the cause of corneal vascularisation, prognosis of keratoplasty on such cases is not disappointing. Rather keratoplasty done on early notified corneal opacity with superficial vascularisation gives satisfactory results .Medicine Today 2016 Vol.28(2): 69-71


2020 ◽  
Vol 36 (4) ◽  
Author(s):  
Sidrah Riaz ◽  
Muhammad Tariq Khan ◽  
Khalid Mehmood ◽  
Mahfooz Hussain ◽  
Sara Riaz

Purpose:  To study the effect of intrastromal Voriconazole for treatment of resistant fungal keratitis in a tertiary care eye hospital in Lahore, Pakistan. Study Design:  Experimental interventional study. Place and Duration of Study:  Avicenna Medical College Hospital, Lahore, from July 2017 to July 2019. Methods:  Sixty four patients were selected. All patients with fugal keratitis were included. The patients with previous corneal scar, mature cataract, endophthalmitis, Panophthalmitis, scleral involvement, impending or frank corneal perforation and uncontrolled diabetic patientswere excluded.Corneal scrapings of all patients were sent for 10% KOH staining. All patients were given intrastromal Voriconazole at 3 to 4 sites in divided doses in one ml syringe with 27-guage needle. Injection was repeated on 4th and 8th day. It was combined by topical antifungal and antibiotic eye drops six hourly. Patients were followed at day two, five, nine, three weeks and at 3 months. Results:  There were 55 males and 9 females. Average size of ulcer was 6.4mm ranging from 5.5mm ± 1.8mm. Fifty six (88%) patient showed improvement while eight (12%) patients ended up in melting of cornea which was managed with tectonic corneal graft. In three (5%) patients penetrating Keratoplasty was done. Conjunctival congestion and ocular pain improved significantly one week after third dose but final visual acuity was not significantly improved due to scarring. Conclusion:  The intrastromal corneal voriconazole is an effective treatment for fungal keratitis in term of healing corneal ulcer, control of infection and saving of eye from corneal perforation and permanent blindness. Key Words:  Voriconazole, Fungal keratitis, Penetrating Keratoplasty.


2015 ◽  
Vol 6 (2) ◽  
pp. 76-77
Author(s):  
Shirin Akhter ◽  
Rumana Nazneen

Total abdominal Hysterectomy are gradually rising in our country. This study has been designed to find out the common indications of abdominal hysterectomy in a tertiary care hospital,. to know the clinical characters of the patients and. o elucidate postoperative complication of abdominal hysterectomy.Methodology : Cross- sectional observational study was done during 1st October 2007 to 30th September 2008. Holy Family Red Crescent Medical College Hospital (HFRCMCH). Total 100 patients were selected following enclusion & exclusion criteria hyperposive sampling. Data were recorded before and after operation and analyzed by SPSS version 15.Result : In the present study patients with leiomyoma of uterus was found to be the major indication of hysterectomy followed by dys functional uterine bleeding (DUB) 18.0%, Pelvic inflammatory disease (PID) 14.0%, chronic cervicitis 10.0%, adenomyosis 10.0%, pelvic endometriosis 6.0%, cervical polyp 2.0%, ovarian cysts 1.0% and chriocarcinoma 1.0%. Mean duration of operation (hour) and hospital stay was 1.15 hours and 7.48 days respectively. Most common complication of present series was fever 20.0% followed by 13.0% had wound infection, 6.0% UTI and 2.0% wound dehiscence.Conclusion : Hysterectomy is now the most widely performed major operation in gynaecology. Indication and post operative complications of hysterectomy varies from region to region.Northern International Medical College Journal Vol.6(2) 2015: 76-77


1970 ◽  
Vol 8 (1) ◽  
pp. 11-16 ◽  
Author(s):  
Sneegdha Poddar ◽  
Razia Sultana ◽  
Rebeka Sultana ◽  
Maruf Mohammad Akbor ◽  
Mohammad Abul Kalam Azad ◽  
...  

The objective of the present study was to evaluate the pattern of adverse drug reactions (ADRs)occurring in cancer patients treated with chemotherapy in tertiary care hospitals in Bangladesh. A prospectivehospital based study over a period of six month was carried out in the Department of oncology, Bangabandhu SheikhMujib Medical University and Dhaka Medical College Hospital. The data were subjected to descriptive analysis. Atotal of 50 patients having ADRs due to cancer chemotherapy were randomly selected. Adverse drug reactions weremostly occurred in the age group between 41-50 years (26%). Considering socio-economic status of cancer patientsmarried persons (82%) have significantly higher risk than unmarried (18%). Prevalence of breast cancer (20%),cervical cancer (14%) and leukemia (16%) were higher and they were treated mostly by adjuvant chemotherapy(46%) and secondly by chemotherapy (38%) alone. In most cases ADRs were developed in patients receivingalkylating agents (40%) and antimetabolites (40%) as anticancer therapy. The five certain ADRs observed in thecurrent study were nausea, stomatitis, alopecia, myelosuppression and increased ESR level in both male and femalepatients. Moreover, hematological system was affected severely by alkylating agents and antimetabolites. Similarstudies covering more patients from different regions are needed to validate our findings.Key words: ADRs; Cancer; Chemotherapy; Tertiary hospital; Bangladesh.DOI: 10.3329/dujps.v8i1.5330Dhaka Univ. J. Pharm. Sci. 8(1): 11-16, 2009 (June)


2021 ◽  
Author(s):  
Mohammad Ismail ◽  
Mohammad Farhad Hussain ◽  
Mohammad Abdullah Al Hasan ◽  
AHM Mustafa Kamal ◽  
Monjur Rahman ◽  
...  

Abstract Background Forcibly displaced Myanmar nationals (FDMNs) or Rohingya refugees are one of the vulnerable groups suffering from different kinds of health problems but have been less reported yet. Therefore, the study was designed to delineate the health problems among FDMNs admitted to Cox’s Bazar Medical College Hospital. Methods This hospital-based cross-sectional study was conducted at the Medicine ward, Cox’s Bazar Medical College Hospital, for a six-month period following approval. Rohingya refugees who were admitted during the study period were approached for inclusion. Informed written consent was ensured prior to participation. A structured questionnaire was used during data collection. Collected information was recorded in case record form. A total of 290 subjects were interviewed. Analysis was performed using the statistical package for social science (SPSS) version 20. Results The mean age of the participants was 48.76±18.67 years (range: 16-91), with a clear male predominance (60.7%). Family size ranged 6-8. All of the participants reported at least one of the illnesses. Of all, 29.66% patients reported disease of the respiratory system, and 26.9% reported disease of the gastrointestinal disease and hepatobiliary system. Accidental injury or injury due to electrocution or thin falls or snake bites was present in 10.4% of the cases. Among the single most common diseases, COPD (20%) was the most frequently observed, and the rest of them were chronic liver disease (13.1%), pulmonary TB (5.5%), ischemic stroke (5.5%), CAP (4.1%), acute coronary syndrome (3.4%), thalassaemia (3.4%) and hepatocellular carcinoma (3.4%). Among the top 6 reported diseases, PTB was more common in elderly individuals (p=0.29). The disease pattern was similar across the sexes among the refugees except community acquisition pneumonia (CAP), which was commonly observed among males (p=.004). Considering different age groups, genitourinary problems were more common in males aged >60 years, and rheumatology and musculoskeletal problems were equally affected in females aged between 40-60 years. Conclusion COPD, CLD and CAP were the most prevalent diseases in FDMN patients who attended the medicine ward of Cox’s Bazar Medical College Hospital. Further exploration is warranted before any policy making and comprehensive plan.


2019 ◽  
Vol 6 (2) ◽  
pp. 416
Author(s):  
Mahroof M. K. ◽  
Shamshad Ahmed Khan ◽  
Prakash Saldanha

Background: The study was conducted to know the prevalence of anemia in rural school children located within 15km radius of Yenepoya Medical college hospital, Mangalore and to study the risk factors associated with anemia also to correlate the detection of anemia by clinical examination and by lab estimation of hemoglobin.Methods: A total of 550 children in the age group of 6-15 years were included in this study. Parental informed consent was obtained. A preplanner questionnaire was used to collect the health and socio demographic details. Blood was collected by venepuncture method and haemoglobin was determined by automated sysmex machine. Diagnosis of anemia was made according to WHO cut off value of Hb.Results: Out of 550 children 114(20.6%) were anemic. There was no significant difference between age and sex. Anemia was found to be more prevalent in children with h/o passing worms, undernourished, pica and low socio-economic status. Out of 550 children 174 children had conjunctival pallor on clinical examination. Among that 58 (33.3%) children had anemia on hemoglobin estimation. Majority of the children 116 (66.7%) who had pallor on clinical examination was found as non-anemic on hemoglobin estimation. On kappa co efficient, statistics showed that two examinations to detect anemia was 18.47 %, which indicates poor agreement.Conclusions: The overall prevalence of anemia among rural population is variable depending upon the region. Major factors which influence the prevalence of anemia were nutrition, socioeconomic status, pica and worm infestation. Clinical diagnosis by examination of pallor is poorly correlated by estimation of haemoglobin, hence anemia cannot be diagnosed by detection of pallor alone and it requires lab haemoglobin estimation to prevent wrong diagnosis of anemia.


2020 ◽  
Vol 14 (2) ◽  
pp. 200-202
Author(s):  
Feroz Ahmed Sohel ◽  
Sanzida Jahan ◽  
Saifullah Russel ◽  
Farzana Zafreen

Introduction: Abortion in Bangladesh is illegal under most situations, but menstrual regulation is often used as a substitute. Abortion can be legally performed by a physician in a hospital if it is necessary to save the life of the mother. A person, who performs an abortion under any other circumstances, including a woman who self-aborts, can be punished by a fine and imprisonment. Objective: To assess the socio-demographic profile of abortion cases attending a tertiary level hospital of Bangladesh. Materials and Methods: This cross-sectional descriptive type of study was carried out among 80 patients at the Gynae ward and out patient department of Dhaka Medical College Hospital from March 2012 to June 2012. The study population was women attending the selected hospital for an abortion or abortion-related complications. Results: Most of the respondents 35(43.8%) were below 25 years of age and all patients were housewives. The maximum number of patients 63(78.8%) had spontaneous abortion, low socio-economic status and majority were multigravidas. It was also found that patients with abortion were mostly in their second (43.8%) and third (21.3%) decade of life. Conclusion: In this study, the commonest reason for termination of pregnancy was unplanned pregnancy. Creating awareness and timely intervention might decrease the number of abortion cases. Journal of Armed Forces Medical College Bangladesh Vol.14 (2) 2018: 200-202


Anaemia during pregnancy is a major health problem throughout the world. The prevalence of anaemia in pregnancy is 41.8% globally and 46% in Bangladesh. It affects both the mother and the baby simultaneously. Women often become anaemic during pregnancy because the demand for iron is increased due to the physiological need for pregnancy. This cross-sectional study was carried out in Savar Gonoshasthaya Kendra project area in Dhaka district. Ninety-Five pregnant women of different gestational ages were selected purposively. Haemoglobin level was estimated by cyanomeath haemoglobin method in the laboratory of Gonoshasthaya Samaj Vittik Medical College Hospital, Savar. Among 95 pregnant women, 41.1% was in 20-24 years age group. The mean age of the respondents was 23.74 years. In terms of socio-economic status, 54.7% of the respondents came from lower middle-class family. 7.4% of the respondents had no formal education, 54.7% had primary level education and only 6.3% had higher education. Maximum of the respondents (88.4%) were housewife. This study revealed that the prevalence of anaemia among pregnant women was 51.6%. Among 51.6 % of the anaemic respondents, 23.2% were mildly anaemic, 26.3% were moderately anaemic and 2.1% were severely anaemic.


2017 ◽  
Vol 7 (3) ◽  
pp. 126-133
Author(s):  
Poly Begum ◽  
Dipti Rani Shaha ◽  
Khalifa Mahmud Walid

Background: The prevalence of gestational diabetes mellitus (GDM) is increasing all over the world and varies widely depending on the region of the country, dietary habits and socio-economic status. The prevalence of GDM with its associated risk factors has important health complications for both mother and child.Objectives: The aim of this study was to evaluate the prevalence of GDM and risk factors associated with it in women attending Diabetic Association Medical College Hospital in Faridpur for ante-natal care.Materials and Methods: In this cross-sectional study, screening for GDM was performed in 303 pregnant women. Women who consented to participate underwent a standardized 2-hour 75 gm oral glucose tolerance test (OGTT). A proforma containing general information on demographic characteristics, socio-economic status, education level, parity, family history of diabetes and past history of GDM etc. was filled in. American Diabetes Association (ADA) criteria for 75 gm 2-hour OGTT was used for diagnosing GDM.Results: A total of 303 women participated in the study and GDM was diagnosed in 22 (7.3%) women. A single abnormal value was observed in additional 33 (10.89%) women. On bivariate analysis risk factors found to be significantly associated with GDM were age, household income, parity, educational level, socio-economic status, hypertension, BMI, weight gain, acanthosis nigricans, family history of diabetes and past history of GDM; but on multivariate analysis only upper middle class and presence of acanthosis nigricans were found to be significantly associated with GDM.Conclusion: This study demonstrates a high prevalence of GDM in Bangladesh. These estimates for GDM may help for new suggestions to prevent and manage gestational diabetes.J Enam Med Col 2017; 7(3): 126-133


2017 ◽  
Vol 8 (1) ◽  
pp. 30-34
Author(s):  
Sharmin Abbasi ◽  
Sehereen Farhad Siddiqua ◽  
Mohammad Noor A Alam ◽  
Suha Jesmin

Background: Endometriosis refers to the presence of endometrial glands and stroma outside the uterine cavity. About 10% causes of infertility are due to endometriosis. In women Anti-Mullerian hormone (AMH) level represents the ovarian follicular pool and has been suggested as the most reliable and reproducible marker to asses ovarian reserve. The gold standard approach of management of endometriosis with subfertility is laparoscopy. The objectives of this stydy are evaluation of AMH levels as a marker of ovarian reserve in subfertile patients with different stages of pelvic endometriosis, and correlate it with laparoscopic surgery.Methods: This was a cross sectional observational study on 59 subfertile patients from January 2014 to January 2017 in Anwer Khan Modern Medical College Hospital (AKMMCH). Main outcome measured on the basis of measurement of AMH levels in correlation with the age, types of subfertility, stages of endometriosis, unilateral or bilateral ovarian involvement, size of the cyst, number of the cyst and the impact of different procedures during laparoscopy on AMH levels.Results: Basal AMH levels significantly lower (p= 0.011 and p =0.001) before and after laparoscopy in primary subfertile patients than secondary subfertile patients and AMH significantly decreased (P<0.024) after laparoscopy in primary subfertile patients. AMH level significantly decreased (P<.001) after laparoscopic surgery of two ovaries. Mean serum AMH levels were decreased in moderate and severe stages of endometriosis after laparoscopy (3.01±.04 ng/ml and 2.15±.03ng/ml). Different surgical procedures of laparoscopy showed significant impact on serum AMH levels, in thermal cauterization (p=0.023) and excision plus cauterization (p=0.001) showed significant decreased of AMH.Conclusion: Serum AMH level decreased in many patients after laparoscopy to such an extent from where future fertility is possible.Birdem Med J 2018; 8(1): 30-34


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