scholarly journals IDENTIFIKASI SENYAWA GARLISIN DAN KUERSETIN SEBAGAI SENYAWA ANTIMIKROBA PADA SEDIAAN BASAH DAN KERING BAWANG PUTIH (Allium sativum L.)

2020 ◽  
Vol 8 (2) ◽  
pp. 176
Author(s):  
Fanny Thresia Yunus ◽  
Ari Suwondo ◽  
Martini Martini
Keyword(s):  
Traditional Medicine ◽  
Allium Sativum ◽  
Chemical Compounds ◽  
The Body ◽  
Garlic Extract ◽  
Antimicrobial Compounds ◽  
Vacuum Oven ◽  
Garlic Powder ◽  
Three Samples

Indonesian people have long used garlic as traditional medicine because it contains various chemical compounds that are beneficial to the body. In this study identification of garlicin and kuersetin compounds in garlic as an antibacterial. This study requires 500 grams of garlic each in wet preparations consist of fine garlic and garlic extract, and dry preparation consists of garlic powder. In addition, this research requires 2,1 liters of 96% ethanol. Garlic is dried at 400C with TMI Vacuum Oven and extracted at 250C. Garlic powder is made using Krisbow dry cabinet with a temperature of 1000F and a pressure of 10 Pa. Garlisin content was identified by GCMS Shimadzu TQ8030 and FTIR Perkin Elmer Spectrum Two UATR, while identification of quercetin using Shimadzu HPLC type UFLC. The result shows that the compound garlicin (C6H10S2) was found in the three samples with identical similarity levels. In addition, the three samples showed differences in kuersetin content. The highest kuersetin content was 458.729 ppm garlic extract while the lowest kuersetin content was 81.181 ppm fresh garlic. Both of these compounds have potential as antimicrobial compounds.

EFEKTIVITAS ANTIBAKTERI BAWANG PUTIH (Allium sativum L) SEBAGAI PENGAWET ALAMI PADA IKAN LELE DUMBO (Clarias gariephinus) SEGAR

2019 ◽  
Vol 14 (1) ◽  
pp. 26
Author(s):  
Dyah Anggraeni ◽  
Nurlela Nurlela
Keyword(s):  
Room Temperature ◽  
Allium Sativum ◽  
Research Result ◽  
Clarias Gariepinus ◽  
Storage Period ◽  
The Body ◽  
Garlic Extract ◽  
African Catfish ◽  
Natural Preservatives ◽  
Colony Counter

Background: Natural preservatives are compounds produced by natural ingredients that can suppress bacterial growth and development. Natural preservatives are carried out because most of the preservatives circulating are chemicals and unsafe for the body. One of the natural preservatives is by using garlic extract (Allium sativum L).  Objective: This study is aimed to determine the effectiveness of the antibacterial garlic (Allium sativum L) as a natural preservative in fresh African catfish (Clarias gariepinus).  Method: This research used the Pour Plate iroculation method. African catfish (Clarias gariepinus) which is soaked with garlic (Allium sativum L) with a concentration of 7%, 14% and 21% for 30 minutes, then the fish will be kept at room temperature with a storage period of 24 hours and 48 hours and calculated growth in bacterial numbers with the Colony counter.  Result: Based on the research result, it was found that garlic extract (Allium sativum L) can obstruct the effectiveness of antibacterial in African catfish (Clarias gariepinus) at a concentration of 14%.

scholarly journals Efficacy of Oral Administration of Allium sativum Powder “Garlic Extract” on Lipid Profile, Inflammation, and Cardiovascular Indices among Hemodialysis Patients

2021 ◽  
Vol 2021 ◽  
pp. 1-7
Author(s):  
Masoumeh Asgharpour ◽  
Armin Khavandegar ◽  
Parastoo Balaei ◽  
Noora Enayati ◽  
Parham Mardi ◽  
...  
Keyword(s):  
Oral Administration ◽  
Lipid Profile ◽  
Allium Sativum ◽  
Venous Blood ◽  
Laboratory Data ◽  
Hemodialysis Patients ◽  
Garlic Extract ◽  
Herbal Remedies ◽  
P Value ◽  
Garlic Powder

Background. Inflammation plays a prominent role in the deteriorating cardiovascular risk of hemodialysis patients. Utilization of herbal remedies, especially garlic extract, in these patients has resulted in promising improvement in lipid profile, inflammation, and cardiovascular markers. Purpose. In this survey, we aimed to determine the effects of oral administration of Allium sativum powder on lipid profile, inflammation, and cardiovascular markers among hemodialysis patients. Methods. In this interventional double-blinded randomized crossover study, 70 patients were enrolled and assigned in two groups. Each group received 300 mg of garlic powder BID or placebo for eight weeks; after a six-week wash-out period, the agents were switched between two groups so that the group who received garlic powder in the first eight weeks received placebo for the second eight weeks, and vice versa. Venous blood samples were obtained in baseline, wash-out period, and at the end of study. Following obtaining laboratory data, BUN, creatinine, Na, K, Ca, Ph, homocysteine, and lipid profile were compared. Results. No significant differences were shown at baselines of outcomes between the garlic and placebo group ( p value>0.05). However, there was a significant decrease in absolute values of OXLDL (mean placebo = 979.63, mean garlic = 676.54; p value<0.001) and HCY (mean placebo = 36.54, mean garlic = 27.78; p value<0.001). In addition, significant treatment differences were seen in change values of Ca (placebo = 1.17, garlic = 0.21; p value = 0.006), TG (placebo = −6.71, garlic = -24.14; p value = 0.014), OXLDL (placebo = −281.30, garlic = -699.78; p value<0.001), and HCY (placebo = −0.24, garlic = −6.68; p value<0.001). Conclusion. In this study, Allium sativum powder demonstrated efficacy in lipid profile improvement and renal protective effects among hemodialysis patients.

scholarly journals Uji Ekstrak Bawang Putih Tunggal (Allium sativum L.) Terhadap Bakteriuria Escherichia coli Pada Calon Pekerja Migran Indonesia

2021 ◽  
Vol 5 (1) ◽  
pp. 50-57
Author(s):  
Indah Sulistiyawati ◽  
Muhammad Falah ◽  
Ari Dwi Nurasih
Keyword(s):  
Escherichia Coli ◽  
Crude Extract ◽  
Migrant Workers ◽  
Allium Sativum ◽  
Positive Control ◽  
The Body ◽  
Garlic Extract ◽  
Urine Samples ◽  
P Value ◽  
E Coli

Garlic (Allium sativum L) is a tested type of phytopharmaca because it is proven to have beneficial benefits as antibacterial and protect the body from pathogens. The majority of Indonesian Migrant Workers, especially Prospective Indonesian Migrant Workers (CPMI), are indicated to be susceptible to Urinary Tract Infection (UTI), which is caused by the bacteriuria Escherichia coli. In this study, the crude extract of single garlic (A. sativum L) will be used as an antibacterial against E. coli bateriuria in the urine sample of CPMI, with variations in the concentration of single crude extract of garlic, namely; 0%, 25%, 50%, 75%, and 100%. This research was conducted in a period of 1 (one) year from January to December 2020, with urine research samples from CPMI in the Banyumas Regency area. Extraction was carried out by extracting a single garlic using 96% ethanol solvent in a ratio of 1: 1, then evaporated to produce a filtrate that would be tested with a varied concentrate composition. Isolation of bacteriuria in urine samples using EMBA selective media. From a total of 37 urine samples, 17 about 46% were positive for E. coli, and 20 samples were 54% negative for E. coli. Bacteriuria that was found challenged with crude garlic extract resulted in differences in the antibacterial test at several extract concentrations with amoxicillin positive control, with One Way Anova a P-value = 0.000 <0.05, and continued with the analysis of the Post Hoc Test and the Tuckey Test, that the garlic extract The single most effective used as an anti-bacterial agent is the concentration of 100%, resulting in an average inhibition of 12.81 mm. The ability of single garlic extract to inhibit increases with increasing extract concentrate.

Updating long-held assumptions about fat stigma: For women, body shape plays a critical role

2020 ◽  
Author(s):  
Jaimie Krems ◽  
Steven L. Neuberg
Keyword(s):  
Body Shape ◽  
Critical Role ◽  
The Body ◽  
Theoretical Assumption ◽  
Obesity Stigma ◽  
Obese Female ◽  
Three Samples ◽  
Female Bodies ◽  
Different Parts ◽  
Fat Stigma

Heavier bodies—particularly female bodies—are stigmatized. Such fat stigma is pervasive, painful to experience, and may even facilitate weight gain, thereby perpetuating the obesity-stigma cycle. Leveraging research on functionally distinct forms of fat (deposited on different parts of the body), we propose that body shape plays an important but largely underappreciated role in fat stigma, above and beyond fat amount. Across three samples varying in participant ethnicity (White and Black Americans) and nation (U.S., India), patterns of fat stigma reveal that, as hypothesized, participants differently stigmatized equally-overweight or -obese female targets as a function of target shape, sometimes even more strongly stigmatizing targets with less rather than more body mass. Such findings suggest value in updating our understanding of fat stigma to include body shape and in querying a predominating, but often implicit, theoretical assumption that people simply view all fat as bad (and more fat as worse).

Garlic Extract (Allium sativum L.) Effectively Inhibits Staphylococcus aureus and Escherichia coli by Invitro Test

2020 ◽  
Vol 2 (2) ◽  
pp. 61-68
Author(s):  
Agnina Listya Anggraini ◽  
Ratih Dewi Dwiyanti ◽  
Anny Thuraidah
Keyword(s):  
Escherichia Coli ◽  
Staphylococcus Aureus ◽  
Bacterial Infections ◽  
Allium Sativum ◽  
Antibacterial Properties ◽  
Herbal Medicines ◽  
Garlic Extract ◽  
Dilution Method ◽  
Initial Stage

Infection is a disease caused by the presence of pathogenic microbes, including Staphylococcus aureus and Escherichia coli. Garlic (Allium sativum L.) has chemical contents such as allicin, alkaloids, flavonoids, saponins, tannins, and steroids, which can function as an antibacterial against Staphylococcus aureus and Escherichia coli. This study aims to determine the antibacterial properties of garlic extract powder against Staphylococcus aureus and Escherichia coli. This research is the initial stage of the development of herbal medicines to treat Staphylococcus aureus and Escherichia coli infections. The antibacterial activity test was carried out by the liquid dilution method. The concentrations used were 30 mg/mL, 40 mg/mL, 50 mg/mL, 60 mg/mL and 70 mg/mL. The results showed that the Minimum Inhibitory Concentration (MIC) against Staphylococcus aureus and Escherichia coli was 40 mg/mL and 50 mg / mL. Minimum Bactericidal Concentration (MBC) results for Staphylococcus aureus and Escherichia coli are 50 mg/mL and 70 mg/mL. Based on the Simple Linear Regression test, the R2 value of Staphylococcus aureus and Escherichia coli is 0.545 and 0.785, so it can be concluded that there is an effect of garlic extract powder on the growth of Staphylococcus aureus and Escherichia coli by 54.5% and 78.5%. Garlic (Allium sativum L.) extract powder has potential as herbal medicine against bacterial infections but requires further research to determine its effect in vivo.

UJI TOKSISITAS AKUT KAPSUL BAWANG PUTIH LANANG (Allium sativum Linn)

2017 ◽  
Vol 2 (2) ◽  
pp. 179
Author(s):  
Lusia Murtisiwi ◽  
Novena Yety Lindawati
Keyword(s):  
Traditional Medicine ◽  
Allium Sativum ◽  
Microbial Pathogens ◽  
Coliform Bacteria ◽  
Plate Count ◽  
Liver Functions ◽  
Dried Extract ◽  
Time Required ◽  
Mold And Yeast ◽  
And Staphylococcus Aureus

Garlic (Allium sativum Linn) is evidently active against Mycobacterium tuberculosis. Garlic contains allicin that is able to inhibit the bacteria causing tuberculosis. This dried extract garlic is also qualified as content of capsules of traditional medicine, score of Total Plate Count is1.5 (required not over 10); figures of mold and yeast extract of garlic is 4.102 (required not over 104); does not contain microbial pathogens (uncontaminated with coliform bacteria, Escherichia coli, Salmonella sp, and Staphylococcus aureus); and aflatoxin is not detected (required not more than 30 CPM); the average of moisture content is 2% (required notmore than 10%). Capsule of dried extract garlic (Allium sativum Linn) meets pharmaceutical requirements for traditional medicine capsule dosage form, with9 minutes as disintegrating time (required not more than 15 minutes) and meets the uniformity of weight as required for capsule. Results of the research indicates that dried extract of garlic indose above 48.750 mg/ kg body weightto get LD50in garlic, belongs to ‘relatively harmless’. Dried extract garlic in 4 doses variations do not affect the liver functions of mice, so significant clinical toxicity symptoms that happen on entire animals test have not gained yet

ACTIVE LONGEVITY: WAYS TO ACHIEVE IN THE CONTEXT OF THE DEVELOPMENT OF INFORMATIONAL-ENERGETIC MEDICINE

Fitoterapia ◽  
2021 ◽  
Vol 2 (2) ◽  
pp. 55-61
Author(s):  
V. V. Krutov ◽  
Keyword(s):  
Traditional Medicine ◽  
Old Age ◽  
The Elderly ◽  
The Body ◽  
Comprehensive Approach ◽  
Allopathic Medicine ◽  
Active Aging ◽  
Synergistic Approach ◽  
Systemic Problems ◽  
Information Energy

Keywords: health, Spirit, energy, synergistic approach, gerontology, quality longevity, allopathic medicine, informational-energetic medicine. The article discusses the issue of active aging strategies that differ from those used in traditional medicine. Practice shows that the resources of the latter are insufficient for successfully overcoming the systemic problems of people, growing with aging and maximum in old age. The accumulation of the problematic nature of the physical body in long-lived people requires a special, comprehensive approach to treatment with penetration into the root nature of a person. Based on innovative knowledge, including data from his own research, the author is talking about a synergistic approach that includes, along with the existing practice of treating the elderly, methods of informational- energetic medicine. Medicine, working at the level of the subtle, causal sphere of a person, where the roots of all his diseases lie and are revealed. This way of solving, the author believes, bears the maximum healing effect for the body on all levels of its multidimensionality – substance, information, energy.

The effect of garlic extract (Allium sativum L.) (Amaryllidaceae) to eradicate the Porphyromonas endodontalis biofilm: An in-vitro research

2021 ◽  
Vol 5 (3) ◽  
pp. 138
Author(s):  
AdiDharma Widjaya ◽  
MeinyFaudah Amin ◽  
Aryadi ◽  
BoediOetomo Roeslan
Keyword(s):  
Allium Sativum ◽  
Garlic Extract
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