scholarly journals Knowledge, Awareness, and Perception of Genetic Testing for Hereditary Disorders Among Malaysians in Klang Valley

2020 ◽  
Vol 11 ◽  
Author(s):  
Jia-Jia Chin ◽  
Hong-Wai Tham

Genetic testing aids patients in making important decisions in the prevention, treatment, or early detection of hereditary disorders. Low awareness of the importance of genetic testing contributes to the increase in the incidence of hereditary disorders. This study aims to explore the knowledge, awareness, and perception of genetic testing for hereditary disorders among local residents of the Klang Valley, Malaysia, and the potential variables that influence their understanding of genetic testing. A survey was conducted in different municipalities of the Klang Valley through self-administered questionnaire assessing the public's knowledge, awareness, and perception of genetic testing. Overall, the results revealed adequate knowledge and positive awareness of genetic testing, in which both were influenced by the respondent's educational level (P < 0.001), field of study (P < 0.001), and status of heard or unheard of genetic testing (P < 0.001). The perception of genetic testing was generally positive and influenced by the respondent's differences in age (P < 0.016), educational level (P < 0.001), field of study (P < 0.001), and status of heard or unheard of genetic testing (P < 0.001). Although positive responses were obtained, ~20.2% of the respondents had never heard of genetic testing. Of the respondents, 24.5% were unwilling to undergo genetic testing, with 25.1% believing that genetic testing tampers with nature and 18% believing that it opposes religion and their beliefs. Such attitude calls for the need to conduct programs to eliminate any misconception, as well as to educate the public to lessen any perceived misunderstanding of the concepts of genetic testing.

2018 ◽  
Vol 7 (4.38) ◽  
pp. 778
Author(s):  
Lye Mei Yi ◽  
Tan Siew Wan ◽  
Kavitha Haldorai ◽  
Abdul Rahman ◽  
Rasheedul Haque ◽  
...  

The purpose of this research is to determine the factors influencing international tourist satisfaction on the public rail services in Klang Valley, Malaysia. This paper provides important contribution to the Malaysian economy due to the growing number of international tourist in recent years. A mixed methodology approach via the use of phenomenological interviews and self-administered questionnaire were use. Structure equation modelling (SEM) revealed three key dimensions of public rail service attributes which is comfort, accessibility, responsiveness and safety. The result indicated that there is significant relationship between comfort, safety and accessibility. Transportation authorities can use these findings as a guide to enhance the quality of life of public rail service users in the future.   


2021 ◽  
Vol 21 (4) ◽  
pp. 804-810
Author(s):  
Nathalie Amado Cornejo ◽  
Consuelo Luna-Muñoz

Introduction: Knowledge about the transmission of HIV in adolescent women is important due to the great risk of contracting said infection. Objective: To determine the association between the educational level and knowledge about the transmission of HIV in female adolescents according to the ENDES year 2019. Methods: Quantitative, observational, retrospective, cross-sectional and analytical study based on the public availability data of the ENDES 2019. Results: Of the 4 668 women in the age range of 15 to 19 years. 30.6% had adequate knowledge about HIV and 69.4% had inadequate knowledge. No association was found between educational level and level of knowledge about HIV transmission. In the multivariate analysis, regarding the wealth index, being non-poor compared to being in extreme poverty has a positive influence on adequate knowledge about HIV (OR: 1.25 95% CI: 1.14–1.38). Conclusion: Knowledge about HIV transmission in adolescent women in Peru is not adequate, no association was found between educational level and knowledge about HIV transmission, nor with place of residence; but if an association was found with the wealth index.


2021 ◽  
pp. 105566562199530
Author(s):  
İlkem Kara ◽  
Aydan Baştuğ Dumbak ◽  
Maviş Emel Kulak Kayıkcı

Introduction: Factors such as teachers’ appropriate support and social interactions have an impact on the academic performance of children with cleft lip and/or palate (CL/P). This study was designed to investigate the perceptions of the teachers and the general public about the academic and cognitive performance of individuals with CL/P. Methods: This study was included 360 (male/female = 102/258) teachers and 640 (male/female = 259/381) participants that represent the general public. Anonymized web-based and paper-and-pencil self-administered questionnaire that included multiple-choice and yes/no questions were administered. Within-group differences and intergroup differences were analyzed in terms of academic and cognitive performance. Results: Most of the teachers and the general public indicated that the academic and cognitive performance of individuals with CL/P is the same as their unaffected peers. A significantly higher proportion of the teachers indicated that the academic performance of children with CL/P is the same as their unaffected peers than the general public. Conclusion: Considering that the general public’s attitudes and appropriate teacher support are crucial to prevent adverse impacts on the lives of individuals with CL/P, it is important to support teachers with the appropriate information and to encourage the public to recognize that everybody with a facial difference should be treated as an individual rather than a disability.


2017 ◽  
Vol 141 (10) ◽  
pp. 1342-1393 ◽  
Author(s):  
Daniel A. Arber ◽  
Michael J. Borowitz ◽  
Melissa Cessna ◽  
Joan Etzell ◽  
Kathryn Foucar ◽  
...  

Context.— A complete diagnosis of acute leukemia requires knowledge of clinical information combined with morphologic evaluation, immunophenotyping and karyotype analysis, and often, molecular genetic testing. Although many aspects of the workup for acute leukemia are well accepted, few guidelines have addressed the different aspects of the diagnostic evaluation of samples from patients suspected to have acute leukemia. Objective.— To develop a guideline for treating physicians and pathologists involved in the diagnostic and prognostic evaluation of new acute leukemia samples, including acute lymphoblastic leukemia, acute myeloid leukemia, and acute leukemias of ambiguous lineage. Design.— The College of American Pathologists and the American Society of Hematology convened a panel of experts in hematology and hematopathology to develop recommendations. A systematic evidence review was conducted to address 6 key questions. Recommendations were derived from strength of evidence, feedback received during the public comment period, and expert panel consensus. Results.— Twenty-seven guideline statements were established, which ranged from recommendations on what clinical and laboratory information should be available as part of the diagnostic and prognostic evaluation of acute leukemia samples to what types of testing should be performed routinely, with recommendations on where such testing should be performed and how the results should be reported. Conclusions.— The guideline provides a framework for the multiple steps, including laboratory testing, in the evaluation of acute leukemia samples. Some aspects of the guideline, especially molecular genetic testing in acute leukemia, are rapidly changing with new supportive literature, which will require on-going updates for the guideline to remain relevant.


2021 ◽  
Vol 19 (16) ◽  
Author(s):  
Rohayu Ab Majid ◽  
Rosli Said ◽  
Jamalunlaili Abdullah ◽  
Rohana Ngah ◽  
Qi Jie Kwong

Light Rail Transit (LRT) is one of the public transports that provides a lot of benefits to the Malaysian. Yet this consumption depends on the diverse tastes of potential ridership which are influenced by various factors. However, it is very challenging to predict significant factors influencing ridership preferences. As such, the identification of these factors is very important in ensuring this transportation service really attract ridership attention. Thus, this paper intends to identify the main factors that influence ridership preference in taking LRT transportation. 28 attributes have been identified in this research which expands from four (4) main components. Data were collected from ridership’s survey, site observations and ridership statistical data. Pearson Chi-square has been employed to justify the significant status and the influence level of each LRT attribute and component factors toward ridership preference. The results show that 23 attributes recorded a significant status (<0.00) in two (2) different directions of correlation. Overall, three (3) component factors namely i) Comfortable Service, ii) Economics and iii) Indoor Environment Conditions, have influenced and contributed to the same effect on ridership considerations, as compared to the negative effects displayed by the Site Design Attributes.


2012 ◽  
Vol 57 (192) ◽  
pp. 7-24 ◽  
Author(s):  
Jelena Lausev

The paper explores the effect of large-scale privatization of public sector activities on public-private sector pay differential, for groups of workers according to educational qualification on average and across the pay distribution in Serbia, from 2004 until 2008. The paper finds that both unskilled and skilled men and women in the public sector saw significant improvements in their financial position relative to their private sector counterparts with the progress of the economic transition. The results showed that the size of the public sector pay premium declines both with higher educational level and higher percentile of earnings distribution. This indicates, between and within groups, the inequality-reducing feature of the public sector pay determination.


2021 ◽  
Vol 1 (1) ◽  
pp. 5-10
Author(s):  
Andreas Putro Ragil Santoso ◽  
Devyana Dyah Wulandari

Diabetes is a disease of metabolic disorders caused by poor production of insulin by the pancreas or due to the use of body insulin which is not maximal, causing interference. The main diabetes that often occurs in the community is type 1 and type 2 diabetes because of the influence of body insulin. Examination for detection is intended so that the public can find out about the presence of glucose in the urine so that the community can immediately recover faster, considering that if there is a glucose level in the urine, there is an increase in the level of glucose in the blood. The method used in this community service is to collect residents at the center, which is then carried out by examining the urine sample using a urine dysptic. Based on the results of examinations carried out on 62 people consisting of mothers and the elderly, it showed that there were 10 positive people or 19% of the total sample. This shows that early detection is important because there are still people who do not know the importance of early detection of disease in themselves, especially in the Kedung Pandan area.


2020 ◽  
Vol 28 (1) ◽  
pp. 20
Author(s):  
Laila Nuranna ◽  
Nessyah Fatahan ◽  
Alfu Nikmatul Laily ◽  
Gatot Purwoto

Objective: Outline the correlation between cervical cancer-related knowledge and voluntary enrollment on early detection of cervical cancer.Material and Methods: Cross sectional design was performed. The inclusion is general practitioner women which currently married. Knowledge and behavior were assessed using questionnaire.Results: Among 367 respondents who filled the questionnaire, 77.4% of them (284) satisfy the inclusion criteria. 56% has high knowledge, and 42.3% has adequate knowledge. Moreover, 62.7% subjects ever performed cervical cancer early detection to themselves; 39.8% with VIA (visual inspection with acetic acid) and 46.5% with Papsmear and/or HPV DNA. Proportion of no early detection history with low and adequate knowledge 1.9 and 1.5 times simultaneously higher than proportion of no early detection with high knowledge. There is no significant correlation between level of knowledge and early detection history.Conclusion: There was no significant correlation between the level of knowlegde and voluntary enrollment for early detection of cervical cancer for general practitioners in Indonesia.


2019 ◽  
Vol 5 (2) ◽  
pp. 15
Author(s):  
Leylawati Joremi

This conceptual paper is presented with the intention to study the best practice model of financial management, which has become the practice of the Malay in Klang Valley.  It begins by reviewing the literature on household financial management and the behavior of households against finances and debt.  The theory of utility and the life-cycle hypothesis were used as the basis of the study.  This study is inspired by the concerns of the government and the public on the growing bankruptcy issue in Malaysia.  Many previous quantitative studies discussed the flaws in money management.  This study, however, slightly different.  Using a qualitative method, it intends to look at the best practices implemented by the household in managing family finances.  The findings can add value to today's body of knowledge.  Identified themes can be used to design financial modules which are more compatible to be used by all levels of society.


PeerJ ◽  
2021 ◽  
Vol 9 ◽  
pp. e10643
Author(s):  
Abdulwakil Olawale Saba ◽  
Ahmad Ismail ◽  
Syaizwan Zahmir Zulkifli ◽  
Shamarina Shohaimi ◽  
Mohammad Noor Amal Azmai

Malaysia is one of the top ten countries in the world that produce freshwater ornamental fishes. This industry can offer better livelihood opportunities to many poor households. However, most of the produced ornamental fishes are alien to Malaysia. In this study, we explore the contribution of alien freshwater fishes to the income of ornamental fish store owners and their attitude towards alien freshwater fishes within Klang Valley, Malaysia. Using a structured questionnaire, we surveyed 70 pet stores out of which 54 (81.42%) store owners responded. Most of the pet store owners were male (72%), Chinese (83%), and the highest educational level was at the secondary level (79%). Most of the pet store owners reported a monthly income of RM 2001–RM 5000 (78%) and were married (73%). Using Chi-square (χ2) test, significant relationships (p < 0.05) existed between the attitude of store owners towards alien ornamental fish species versus educational level (χ2 = 16.424, p = 0.007) and contribution of alien ornamental fishes to the pet store owners’ income (χ2 = 27.266, p = 0.003). Fish sales as the main income source also related significantly with the impact of fish selling business on income level (χ2 = 10.448, p = 0.007). This study showed that the ornamental fish sales contributed over half of the income (51–100%) from the businesses of store owners. Almost half of the respondents (42%) reported that alien ornamental fish was the highest contributor to their income from the ornamental fish sale. While the mismanagement of alien ornamental fishes could give various negative ecological impacts, the socio-economic benefits of these fishes cannot be denied.


Sign in / Sign up

Export Citation Format

Share Document