scholarly journals WYMIENNOŚĆ PARTNERÓW ASPEKTOWYCH, CZYLI KILKA UWAG NA TEMAT IRRELEWANCJI ASPEKT

2021 ◽  
pp. 51-62
Author(s):  
Beata Terka
Keyword(s):  
Foreign Language ◽  
Material Research ◽  
Grammatical Category ◽  
Starting Point ◽  
Polish Language ◽  
Good Starting Point

This paper discusses the issue of irrelevance of the aspect of the Polish verb. In specifi c contexts, the grammatical category of aspect, being obligatory in the Polish language, is in fact redundant. The identifi cation of such contexts (and hence review of the most important current observations and convictions in this respect), the attempt at ordering and describing them enabled systematic material research based on a (Polish–German and German–Polish) translation. The fi ndings presented in the paper might be a good starting point for a refl ection on the reasonability of including the described issue in curricula of teaching Polish as a foreign language. Due to its reach and frequency, the phenomenon of alternation of aspectual partners should be more frequently discussed in the literature dedicated to aspect and Polish glottodidactics

scholarly journals Looking for the traces of Polish heritage on the map of Ukraine. Linguistic educational game

2021 ◽  
pp. 297-302
Author(s):  
Barbara Januszkiewicz
Keyword(s):  
Young People ◽  
Foreign Language ◽  
Cultural Heritage ◽  
Educational Game ◽  
Board Game ◽  
The Past ◽  
Starting Point ◽  
Polish Language ◽  
The Common ◽  
Game Board

The article describes the idea for an educational game Polskie dziedzictwo na mapie Podola (Polish Heritage on the Map of Podolia) aimed at learning Polish as foreign language using a historical map. The article presents a map (as a game board) that was drawn up by a 17th-century cartographer Guillaume Le Vasseur de Beauplan. The map of Podolia provides a starting point for preparing scenarios of educational classes that would present historic figures, places, events and architectural monuments connected with Poland. The game is supposed to enhance the interest in learning Polish and teach respect for the common historical and cultural heritage, as well as encourage young people to study the past and discover their ‘personal homeland’. The author of the article suggests to use the board game as part of teaching the Polish language, which would certainly make linguistic education more attractive.

scholarly journals Teaching Spoken Production in Global Contexts 2021

2021 ◽  
Vol 12 (4) ◽  
pp. 213-223
Author(s):  
Nilakshi Phukan ◽  
Svitlana Volkova ◽  
Kateryna Tuliakova ◽  
Oleksandr Pasichnyk ◽  
Yuliya Kornytska
Keyword(s):  
Foreign Language ◽  
Professional Training ◽  
Professional Competence ◽  
Language Competence ◽  
Starting Point ◽  
Law Faculty ◽  
Good Starting Point ◽  
Methodological Principles ◽  
Kyiv Polytechnic Institute ◽  
Methodological Guidelines

Shaping and developing communication skills in non-linguistic faculties in higher education institutions remain relevant. Thus, the theoretical and methodological guidelines for training English professionally-oriented spoken production are among significant problems. Intending to overcome some related challenges, we conducted this study to investigate the efficiency of using presentational speeches based on authentic video materials. The main aim of the research was to analyze the problem from methodological and didactic perspectives and substantiate the theoretical and methodological principles of the professional training of monolingual students through the experimental verification of the effectiveness of the proposed methodology. To achieve the objectives of this study, in the first stage, we determined the efficiency of pedagogical conditions for developing the foreign language competence of students. Then we verified the efficiency of using presentational speeches in teaching Spoken Production. At the last stage, we analyzed the effectiveness of the proposed methods of forming and developing foreign language competence (Spoken Production) by using presentational speeches. The study sample included 45 students of the Sociology and Law Faculty in the National Technical University of Ukraine “Igor Sikorsky Kyiv Polytechnic Institute”. We obtained the results that confirmed the efficiency of the presentational speech approach in teaching spoken production. Our study revealed that the presentational speech approach facilitates enhancement in the level of students’ professional competence. These findings provide a good starting point for discussion and further research.

scholarly journals Rola imienia we wczesnoszkolnym nauczaniu języków nierodzimych

1970 ◽  
Vol 20 ◽  
Author(s):  
Karolina Adryan
Keyword(s):  
Foreign Language ◽  
Reading Skills ◽  
Foreign Language Teaching ◽  
Professional Experience ◽  
Language Fluency ◽  
Pedagogical Innovation ◽  
Learning To Read ◽  
Starting Point ◽  
Good Starting Point ◽  
Bilingual School

The article focuses on the effectiveness of the name-based method (Odimienna Metoda Nauki Czytania) developed by Irena Majchrzak in foreign language teaching to young pupils. Children’s names prove a good starting point for learning to read in a foreign language. As a valuable educational material of emotional charge, the name constitutes an integral part of the learner and thus can be used as a personalised primer containing a basic text to be the first read by children. Originally used to teach reading in Polish kindergartens, the name-based method may inspire teachers in teaching a foreign language to young learners as an ingenious pedagogical innovation. My professional experience indicates that the reading skills in a foreign language in the first stage of education are underestimated. My data come from a six-month experiment in a primary bilingual school where I introduced the name-based method. As a result, the children’s own names in their foreign language versions provided an excellent educational basis. The conclusions reveal that this method helps in expanding vocabulary, developing linguistic sensitivity, stimulating communication skills, and positively affecting language fluency.

scholarly journals Teaching Spoken Production in Global Contexts 2021

2022 ◽  
Author(s):  
Nilakshi Phukan ◽  
Svitlana Volkova ◽  
Kateryna Tuliakova ◽  
Oleksandr Pasichnyk ◽  
Yuliya Kornytska
Keyword(s):  
Foreign Language ◽  
Professional Training ◽  
Professional Competence ◽  
Language Competence ◽  
Starting Point ◽  
Law Faculty ◽  
Good Starting Point ◽  
Methodological Principles ◽  
Kyiv Polytechnic Institute ◽  
Methodological Guidelines

Shaping and developing communication skills in non-linguistic faculties in higher education institutions remain relevant. Thus, the theoretical and methodological guidelines for training English professionally-oriented spoken production are among significant problems. Intending to overcome some related challenges, we conducted this study to investigate the efficiency of using presentational speeches based on authentic video materials. The main aim of the research was to analyze the problem from methodological and didactic perspectives and substantiate the theoretical and methodological principles of the professional training of monolingual students through the experimental verification of the effectiveness of the proposed methodology. To achieve the objectives of this study, in the first stage, we determined the efficiency of pedagogical conditions for developing the foreign language competence of students. Then we verified the efficiency of using presentational speeches in teaching Spoken Production. At the last stage, we analyzed the effectiveness of the proposed methods of forming and developing foreign language competence (Spoken Production) by using presentational speeches. The study sample included 45 students of the Sociology and Law Faculty in the National Technical University of Ukraine “Igor Sikorsky Kyiv Polytechnic Institute”. We obtained the results that confirmed the efficiency of the presentational speech approach in teaching spoken production. Our study revealed that the presentational speech approach facilitates enhancement in the level of students’ professional competence. These findings provide a good starting point for discussion and further research.

scholarly journals Discovery and Optimization of Selective Inhibitors of Meprin α (Part I)

2021 ◽  
Vol 14 (3) ◽  
pp. 203 ◽  
Author(s):  
Shurong Hou ◽  
Juan Diez ◽  
Chao Wang ◽  
Christoph Becker-Pauly ◽  
Gregg B. Fields ◽  
...  
Keyword(s):  
Inhibitory Activity ◽  
De Novo ◽  
Selective Inhibitors ◽  
Preclinical Development ◽  
Starting Point ◽  
Good Starting Point ◽  
Parallel Screening ◽  
Low Cytotoxicity

Meprin α and β are zinc-dependent proteinases implicated in multiple diseases including cancers, fibrosis, and Alzheimer’s. However, until recently, only a few inhibitors of either meprin were reported and no inhibitors are in preclinical development. Moreover, inhibitors of other metzincins developed in previous years are not effective in inhibiting meprins suggesting the need for de novo discovery effort. To address the paucity of tractable meprin inhibitors we developed ultrahigh-throughput assays and conducted parallel screening of >650,000 compounds against each meprin. As a result of this effort, we identified five selective meprin α hits belonging to three different chemotypes (triazole-hydroxyacetamides, sulfonamide-hydroxypropanamides, and phenoxy-hydroxyacetamides). These hits demonstrated a nanomolar to micromolar inhibitory activity against meprin α with low cytotoxicity and >30-fold selectivity against meprin β and other related metzincincs. These selective inhibitors of meprin α provide a good starting point for further optimization.

scholarly journals Advances on the Implementation of Circular Economy Techniques in Rural Areas in Colombia under a Sustainable Development Framework

2021 ◽  
Vol 13 (7) ◽  
pp. 3816
Author(s):  
Javier Rodrigo-Ilarri ◽  
Camilo-A. Vargas-Terranova ◽  
María-Elena Rodrigo-Clavero ◽  
Paula-A. Bustos-Castro
Keyword(s):  
Sustainable Development ◽  
Waste Management ◽  
Circular Economy ◽  
Rural Areas ◽  
Development Framework ◽  
Starting Point ◽  
Management Plans ◽  
Good Starting Point ◽  
Depressed Regions ◽  
First Time

For the first time in the scientific literature, this research shows an analysis of the implementation of circular economy techniques under sustainable development framework in six municipalities with a depressed economy in Colombia. The analysis is based on solid waste data production at a local scale, the valuation of the waste for subsequent recycling, and the identification and quantification of the variables associated with the treatment and final disposal of waste, in accordance with the Colombian regulatory framework. Waste generation data are obtained considering three different scenarios, in which a comparison between the simulated values and those established in the management plans are compared. Important differences have been identified between the waste management programs of each municipality, specifically regarding the components of waste collection, transportation and disposal, participation of environmental reclaimers, and potential use of materials. These differences are fundamentally associated with the different administrative processes considered for each individual municipality. This research is a good starting point for the development of waste management models based on circular economy techniques, through the subsequent implementation of an office tool in depressed regions such as those studied.

Industry-Sponsored Medical Education — In the Quest for Professional Integrity and Legal Certainty

2007 ◽  
Vol 14 (4) ◽  
pp. 313-319
Author(s):  
Benedikt Buchner
Keyword(s):  
Medical Education ◽  
Self Regulation ◽  
State Regulation ◽  
General Question ◽  
Legal Certainty ◽  
European Directive ◽  
Starting Point ◽  
Good Starting Point ◽  
Advertising Law ◽  
The Right

AbstractIndustry-sponsored medical education is a much disputed issue. So far, there has been no regulatory framework which provides clear and definite rules as to whether and under what circumstances the sponsorship of medical education is acceptable. State regulation does not exist, or confines itself to a very general principle. Professional regulation, even though applied frequently, is rather vague and indefinite, raising the general question as to whether self-regulation is the right approach at all. Certainly, self-regulation by industry cannot and should not replace other regulatory approaches. Ultimately, advertising law in general and the European Directive 2001/83/EC specifically, might be a good starting point in providing legal certainty and ensuring the independence of medical education. Swiss advertising law illustrates how the principles of the European Directive could be implemented clearly and unambiguously.

scholarly journals Multiple Myeloma Inhibitory Activity of Plant Natural Products

Cancers ◽  
2021 ◽  
Vol 13 (11) ◽  
pp. 2678
Author(s):  
Karin Jöhrer ◽  
Serhat Sezai Ҫiҫek
Keyword(s):  
Multiple Myeloma ◽  
Natural Products ◽  
Myeloma Cell ◽  
Myeloma Cell Line ◽  
Antiproliferative Effects ◽  
Plant Natural Products ◽  
Starting Point ◽  
Human Myeloma Cell Line ◽  
Group A ◽  
Good Starting Point

A literature search on plant natural products with antimyeloma activity until the end of 2020 resulted in 92 compounds with effects on at least one human myeloma cell line. Compounds were divided in different compound classes and both their structure–activity-relationships as well as eventual correlations with the pathways described for Multiple Myeloma were discussed. Each of the major compound classes in this review (alkaloids, phenolics, terpenes) revealed interesting candidates, such as dioncophyllines, a group of naphtylisoquinoline alkaloids, which showed pronounced and selective induction of apoptosis when substituted in position 7 of the isoquinoline moiety. Interestingly, out of the phenolic compound class, two of the most noteworthy constituents belong to the relatively small subclass of xanthones, rendering this group a good starting point for possible further drug development. The class of terpenoids also provides noteworthy constituents, such as the highly oxygenated diterpenoid oridonin, which exhibited antiproliferative effects equal to those of bortezomib on RPMI8226 cells. Moreover, triterpenoids containing a lactone ring and/or quinone-like substructures, e.g., bruceantin, whitaferin A, withanolide F, celastrol, and pristimerin, displayed remarkable activity, with the latter two compounds acting as inhibitors of both NF-κB and proteasome chymotrypsin-like activity.

COVID-19, Business, and Human Rights

2021 ◽  
Vol 23 (5) ◽  
pp. 433-449
Author(s):  
Surya Deva
Keyword(s):  
Human Rights ◽  
Full Range ◽  
International Human Rights Law ◽  
Human Rights Law ◽  
International Human Rights ◽  
Economic Problems ◽  
Business And Human Rights ◽  
Starting Point ◽  
Good Starting Point ◽  
International Human

Abstract COVID-19 has affected the full range of human rights, though some rights holders have experienced a disproportionate impact. This has triggered debate about the respective obligations and responsibilities of states and business enterprises under international human rights law. Against this backdrop, this article examines critically whether the “protect, respect and remedy” framework operationalised by the UN Guiding Principles on Business and Human Rights is “fit for the purpose” to deal with the COVID-19 crisis. I argue that while the UNGPs’ framework provides a good starting point, it is inadequate to bring transformative changes to overcome deep-rooted socio-economic problems exposed by this pandemic. Realising human rights fully would not only require harnessing the potential of states’ tripartite obligations, but also move beyond limiting the responsibility of businesses to respect human rights.

Water Depollution Control : A Gateway to Reaction Monitoring and Analytical Chemistry

2021 ◽  
Author(s):  
Martin Tiano ◽  
Max Roose
Keyword(s):  
Analytical Chemistry ◽  
Undergraduate Students ◽  
Environmental Chemistry ◽  
Organic Pollutant ◽  
Internal Standard ◽  
Experimental Session ◽  
Reaction Monitoring ◽  
Starting Point ◽  
Good Starting Point ◽  
Magnetite Particles

<div>We present here an experimental session for undergraduate students, based on the reaction monitoring of the degradation of an organic pollutant (para-nitrophenol) by a Fenton-like reaction, catalysed by magnetite particles. <br></div><div>During the session, students realized a follow-up of the reaction by Gas Chromatography with an internal standard, and by UV-Visible spectrophotometry. <br></div>This session was a good starting point to numerous discussions about analytical chemistry, environmental chemistry.

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