scholarly journals Influence of Cane Molasses Inclusion to Dairy Cow Diets during the Transition Period on Rumen Epithelial Development

Animals ◽  
2021 ◽  
Vol 11 (5) ◽  
pp. 1230
Author(s):  
William F. Miller ◽  
Evan C. Titgemeyer ◽  
Tiruvoor G. Nagaraja ◽  
Daniel H. M. Watanabe ◽  
Luana D. Felizari ◽  
...  
Keyword(s):  
Volatile Fatty Acids ◽  
Transition Period ◽  
Dry Period ◽  
Cane Molasses ◽  
Transition Cow ◽  
Rumen Epithelium ◽  
Epithelial Development ◽  
Milk Performance ◽  
Glucagon Like Peptide ◽  
Cow Performance

The objective of this study was to evaluate the addition of cane molasses during a 60 day dry period on performance and metabolism of Holstein cows during prepartum and postpartum periods. For experiment 1, 26 primiparous and 28 multiparous cows were used. Upon freshening, all cows were offered a common lactation diet. For experiment 2, six multiparous cows fitted with rumen cannulas were used to measure performance and metabolism, following the same protocol as experiment 1. Ruminal propionate increased by 10% during both prepartum and postpartum periods; however, papillae area was greater for cows not fed molasses, and volatile fatty acids (VFA) absorption from the rumen was not increased, resulting in similar glucagon-like-peptide-2 receptor (GLP-2R) density. The improved dry matter intake, when molasses was added into prepartum diets, translated into increased milk yield and energy-corrected milk (ECM) in Experiment 1 only for multiparous cows. For experiment 2, the improvement on milk performance was also observed, where cows fed molasses had 18.5% greater ECM production. Feeding molasses during a 60 day dry period positively influenced transition cow performance, and it was not accompanied by changes in rumen morphometrics; however, this indicates enhanced adaptation by the rumen epithelium based on similar capabilities for VFA absorption.

An examination of the effects of level of energy intake and source of nutrients during late gestation on subsequent milk yield and composition of lactating dairy cattle

2000 ◽  
Vol 2000 ◽  
pp. 36-36
Author(s):  
T.W.J. Keady ◽  
C.S. Mayne ◽  
D A Fitzpatrick
Keyword(s):  
Energy Intake ◽  
Milk Yield ◽  
Milk Fat ◽  
Nutrient Intake ◽  
Volatile Fatty Acids ◽  
Transition Period ◽  
Late Gestation ◽  
Dry Period ◽  
Foetal Growth ◽  
Lactating Dairy Cattle

The transition period of the dairy cow is physiologically and nutritionally stressful, particularly as feed intake is reduced and nutrient demands for foetal growth and initiation of milk synthesis are increased. It has been suggested that feeding concentrates in late gestation promotes the development of ruminal papillae, which takes 4 to 6 weeks to fully develop, consequently resulting in improved absorption of volatile fatty acids and increased food intake during early lactation. A recent study undertaken at this Institute (Keady et al. 1999) concluded that relative to silage offered ad libitum as the sole diet supplementation with 5 kg of concentrate during the last 28 days of gestation increased milk fat by 1.5 g/kg and improved milk yield by 0.6 kg/day during the first 12 weeks of the subsequent lactation. The response to dry cow supplementation reported by Keady et al. (1999) could have been mediated either by increased nutrient intake or by changes in the forage to concentrate ratio of the diet during the dry period. The present study was undertaken to evaluate the effect of level of energy intake and source of nutrients in late gestation on subsequent milk yield and composition.

scholarly journals MicroRNA profiles of dry secretions through the first three weeks of the dry period from Holstein cows

2019 ◽  
Vol 9 (1) ◽  
Author(s):  
Ellie J. Putz ◽  
Austin M. Putz ◽  
Hyeongseon Jeon ◽  
John D. Lippolis ◽  
Hao Ma ◽  
...  
Keyword(s):  
Regression Models ◽  
Transition Period ◽  
Mirna Profile ◽  
Random Regression ◽  
Q Value ◽  
Dry Period ◽  
Regulate Gene Expression ◽  
Intramammary Infections ◽  
Non Coding Rnas ◽  
Insight Into

AbstractIn dairy cows, the period from the end of lactation through the dry period and into the transition period, requires vast physiological and immunological changes critical to mammary health. The dry period is important to the success of the next lactation and intramammary infections during the dry period will adversely alter mammary function, health and milk production for the subsequent lactation. MicroRNAs (miRNAs) are small non-coding RNAs that can post transcriptionally regulate gene expression. We sought to characterize the miRNA profile in dry secretions from the last day of lactation to 3, 10, and 21 days post dry-off. We identified 816 known and 80 novel miRNAs. We found 46 miRNAs whose expression significantly changed (q-value < 0.05) over the first three weeks of dry-off. Additionally, we examined the slopes of random regression models of log transformed normalized counts and cross analyzed the 46 significantly upregulated and downregulated miRNAs. These miRNAs were found to be associated with important components of pregnancy, lactation, as well as inflammation and disease. Detailing the miRNA profile of dry secretions through the dry-off period provides insight into the biology at work, possible means of regulation, components of resistance and/or susceptibility, and outlets for targeted therapy development.

scholarly journals The Effectiveness of the Use of Enzymatic Hydrolyzate with Amino Acids, Vitamins and Minerals to Highly Productive Cows in the Transition Period

2020 ◽  
Author(s):  
А.М. Френк ◽  
Е.М. Гриневская ◽  
А.И. Фролов ◽  
А.Н. Бетин ◽  
Н.И. Маслова
Keyword(s):  
Transition Period ◽  
Live Weight ◽  
Gastrointestinal Diseases ◽  
Feed Additive ◽  
Dry Period ◽  
Young Stock ◽  
Service Period ◽  
Farm Scale ◽  
Feces Analysis ◽  
Experimental Group

В условиях научно-производственного опыта исследована эффективность введения кормовой добавки «Абиотоник» в рацион высокопродуктивных голштинизированных симментальских коров (в транзитный период и на раздое). «Абиотоник» представляет собой усовершенствованный аналог известного импортного препарата «Чиктоник», отличаясь от иностранного аналога многократно увеличенной концентрацией пептона и наличием высокодефицитных микроэлементов (селена и элементоорганического соединения йода). Наши исследования показали, что скармливание препарата «Абиотоник» в дозе 150 мл/гол. способствовало росту продуктивности коров на 5,84%, улучшило физико-химические свойства молока и повысило его пищевую ценность. Применение кормовой добавки способствовало также профилактике желудочно-кишечных заболеваний у коров, повышению их резистентности, о чём свидетельствовали показатели крови и бактериологического исследования кала. Заболеваемость коров в опытной группе не наблюдалась. Использование препарата «Абиотоник» коровам в заключительной стадии сухостойного периода и в начале лактации привело к сокращению времени отделения плаценты у коров после отёла на 6,54%, или на 0,4 часа, повышению живой массы новорождённого молодняка на 1,6% и сокращению сервис-периода у опытных коров на 8 дней по сравнению с контрольными. Использование кормовой добавки «Абиотоник» способствовало получению дополнительного дохода от реализации молока в размере 1152 руб./гол. Полученные экспериментальные данные позволяют рекомендовать использование отечественной импортозамещающей кормовой добавки «Абиотоник» в рационах коров транзитного периода и на раздое в дозе 150 мл/гол. ежедневно в последней фазе сухостоя и через день в течение 40 суток после отёла. Under the conditions of scientific and farm scale trial the efficiency of introduction of the feed additive "Abiotonic" into the diet of highly productive Holsteinized Simmental cows (during the transition period and for days in milk) was studied. "Abiotonic" is an improved analogue of the known imported preparation "Chiktonik" differing from the foreign analogue by its manifoldly increased peptone concentration and the presence of highly deficient microelements (selenium and organo-element compounds of iodine). Our researches have shown that feeding the preparation "Abiotonic" at a dose of 150 ml / head contributed to an increase in cow productivity by 5.84%, improved the physicochemical properties of milk and increased its nutritional value. The use of a feed additive also contributed to the prevention of gastrointestinal diseases in cows, an increase in their resistance as evidenced by haematological parameters and bacteriological feces analysis. The incidence of cows in the experimental group was not observed. The use of the preparation "Abiotonic" for cows in the final stage of the dry period and at the beginning of lactation reduced the time for separation of the placenta in cows after calving by 6.54% or 0.4 hours, increased the live weight of newborn young stock by 1.6% and reduced the service period of experienced cows by 8 days compared with the control ones. The use of the "Abiotonic" feed additive contributed to the receipt of additional income from the sale of milk in the amount of 1152 rubles / head. The obtained experimental data allow us to recommend the use of domestic import-substituting feed additive "Abiotonic" in the diets of cows in the transition period and for days in milk at a dose of 150 ml / head daily in the last phase of dry period and every other day for 40 days after calving.

Fertility and the transition dairy cow

2018 ◽  
Vol 30 (1) ◽  
pp. 85 ◽  
Author(s):  
J. R. Roche ◽  
C. R. Burke ◽  
M. A. Crookenden ◽  
A. Heiser ◽  
J. L. Loor ◽  
...  
Keyword(s):  
Metabolic Diseases ◽  
Transition Period ◽  
Fold Increase ◽  
Negative Energy ◽  
Smooth Transition ◽  
Ovarian Activity ◽  
Transition Cow ◽  
Research Findings ◽  
Metabolic Challenge

The transition from pregnancy to lactation (i.e. the transition period) is a time of significant metabolic challenge, with a several-fold increase in a cow’s requirement for energy, protein and minerals within days of calving. A successful transition involves the initiation and coordination of changes in multiple tissues that facilitate the provision of these nutrients to the cow and, more specifically, to the mammary gland, often at the considerable expense of other tissues. Failure to coordinate the necessary changes effectively results in transition period maladaptation, which can broadly be grouped into three categories: (1) negative energy balance and metabolic diseases associated with energy metabolism; (2) immune dysfunction and inflammation; and (3) metabolic diseases associated with mineral deficiency. Because reinitiation of ovarian activity, follicle recruitment, ovulation, fertilisation and, potentially, even maternal recognition of pregnancy and implantation occur against the backdrop of this metabolic and immunological disturbance in early lactation, the role of nutrition in ensuring a smooth transition between the pregnant and lactating state is important. In this paper we integrate recent research findings with previous knowledge of the interaction between transition cow metabolism and nutrition and reproductive outcomes, and offer new insights into key elements of successful cow management to avoid transition ‘maladaptation’ and improve pregnancy rates.

scholarly journals The relationship between transition period diseases and lameness, feeding time, and body condition during the dry period

2020 ◽  
Vol 103 (1) ◽  
pp. 649-665 ◽  
Author(s):  
Ruan R. Daros ◽  
Hanna K. Eriksson ◽  
Daniel M. Weary ◽  
Marina A.G. von Keyserlingk
Keyword(s):  
Body Condition ◽  
Transition Period ◽  
Feeding Time ◽  
Dry Period ◽  
The Relationship

The nexus between nutrient metabolism, oxidative stress and inflammation in transition cows

2014 ◽  
Vol 54 (9) ◽  
pp. 1204 ◽  
Author(s):  
L. M. Sordillo ◽  
V. Mavangira
Keyword(s):  
Oxidative Stress ◽  
Inflammatory Responses ◽  
Metabolic Stress ◽  
Dry Period ◽  
Nutrient Metabolism ◽  
Transition Cow ◽  
Control Programs ◽  
Transition Cows ◽  
Cow Health ◽  
Global Population

Increased incidence of several economically important diseases (i.e. mastitis, metritis, displaced abomasum and ketosis) causes significant animal welfare problems and production losses in transition dairy cattle and decreases the availability of safe and nutritious food for a growing global population. A major underlying factor responsible for the development of transition cow disorders is metabolic stress, which occurs when cows fail to adapt physiologically to an increase in nutrient requirements needed for parturition and the onset of copious milk synthesis and secretion. Metabolic stress can be characterised as resulting from the combined effects of altered nutrient metabolism, dysfunctional inflammatory responses, and oxidative stress. Together, these factors form destructive feedback loops that exacerbate metabolic stress and cause health disorders in transition cows. A better understanding of how nutrition and immunology interact to influence metabolic stress will facilitate the development of control programs to improve transition cow health. The ability to detect signs of metabolic stress early enough in the dry period to implement needed management adjustments before calving will be the key to successful monitoring and intervention programs.

scholarly journals Activation of volatile fatty acids in bovine liver and rumen epithelium. Evidence for control by autoregulation

1973 ◽  
Vol 136 (2) ◽  
pp. 311-319 ◽  
Author(s):  
R. Ash ◽  
G. D. Baird
Keyword(s):  
Fatty Acids ◽  
Fatty Acid ◽  
Volatile Fatty Acid ◽  
Volatile Fatty Acids ◽  
Bovine Liver ◽  
Mitochondrial Matrix ◽  
Rumen Epithelium

1. The total capacities of homogenates of bovine liver and rumen epithelium to activate acetate, propionate and butyrate were determined. 2. Activating capacities were assayed by measuring the rate of formation of the corresponding CoA esters. The methods used for determining the concentrations of the CoA esters allowed the CoA esters of acetate, propionate and butyrate to be distinguished. It was thus possible to investigate the effect of the presence of a second volatile fatty acid on the rate at which a given volatile fatty acid was activated. 3. The propionate-activating capacity in rumen epithelium was decreased by about 87% in the presence of butyrate, the acetate-activating capacity in liver was decreased by about 55% in the presence of either propionate or butyrate, and the butyrate-activating capacity in liver was decreased by about 40–50% in the presence of propionate. 4. All three activating capacities in liver appeared to be located in the mitochondrial matrix and membrane. The three activating capacities had similar locations to each other in rumen epithelium as well, although in this case activity was more evenly divided between the mitochondria and the cytoplasm. 5. The relative activating capacities towards the volatile fatty acids in the two tissues, together with the ability of one volatile fatty acid to inhibit the activation of another volatile fatty acid, appear to ensure that butyrate is mainly metabolized in the rumen epithelium and that propionate is metabolized in the liver.

Sites of organic acid production and absorption in gastrointestinal tract of the pig

1975 ◽  
Vol 228 (2) ◽  
pp. 454-460 ◽  
Author(s):  
RA Argenzio ◽  
M Southworth
Keyword(s):  
Fatty Acids ◽  
Gastric Mucosa ◽  
Organic Acid ◽  
Intestinal Mucosa ◽  
Volatile Fatty Acids ◽  
Control Diet ◽  
Organic Acid Production ◽  
Rumen Epithelium ◽  
High Concentrations ◽  
Digesta Passage

The relationship between diet, pH, and microbial digestion of carbohydrate was examined in 24 pigs fed either a conventional or a low-protein, high-cellulose experimental diet and sacrificed 2, 4, 8, or 12 h after a meal. In animals fed the control diet contents of the cranial half of the stomach demonstrated marked, cyclic fluctuations in pH and high concentrations of organic acids. Contents of the caudal (glandular) half were lower in both pH and organic acid concentration. Despite concentrations of volatile fatty acids (VFAs) as high as 250 meq/liter in the large intestine, the pH remained relatively neutral. The VFA levels remained relatively constant throughout the length of the colon. The VFA transport across isolated gastric and large intestinal mucosa also was examined. All four types of gastric mucosa absorbed and transported VFA at substantial rates. Mucosa of pig cecum and colon transported VFA at much greater rates than gastric mucosa and greater rates than previously determined in equine large intestinal mucosa or even bovine rumen epithelium. Comparison with results of earlier studies in the pony suggested that the higher concentration of VFA in the large intestinal contents of pigs was due to the more rapid rate of digesta passage rather than to less efficient absorption of fatty acids.

Rice polishings as an alternative to sugar cane molasses as a supplement with urea to low-quality forage diets for ruminants

1993 ◽  
Vol 56 (1) ◽  
pp. 85-92 ◽  
Author(s):  
D. Cardenas Garcia ◽  
C. J. Newbold ◽  
H. Galbraith ◽  
J. H. Topps ◽  
X. B. Chen ◽  
...  
Keyword(s):  
Sugar Cane ◽  
Dry Matter ◽  
Volatile Fatty Acids ◽  
Latin Square ◽  
Experimental Period ◽  
Rumen Fermentation ◽  
Cane Molasses ◽  
Mean Values ◽  
Rumen Ph ◽  
Protein Supply

AbstractThe effect of including 14 g urea with either 75 g dry matter (DM) from sugar cane molasses (UM) or Colombian rice polishings (RP) at three levels, 68 (RP1), 137 (RP2) or 203 (RP3) g DM on grass hay DM intake and on rumen fermentation was investigated. An incomplete Latin-square design was used and each experimental period was divided into 12 days for adaptation to each diet followed by 9 days in metabolism cages when all measurements were made using five adult sheep.Pooled mean values for rumen metabolites (five samples per day) were calculated. Rumen pH was not affected by the nature of the supplements. Concentrations of volatile fatty acids (VFA) (UM 92·8, RP1 84·2, RP2 86·4, and RP3 84·0 (s.e.d. 3·4) mmol/l) and lactate (UM 2·0, RP1 1/6, RP2 1/7, RP3 1/8 (s.e.d. 0·014) mmol/l) (UM v. RP, P < 0·05 and P < 0·10 respectively) were lower when RP were given, while concentration of branched and longer chain VFA (26·5, 34·0, 31·1 and 33·5 (s.e.d. 1·6) mmol/mol total VFA, UM v. RP, P < 0·01) and ammonia (98, 131, 141, 137 (s.e.d. 16·1) mg/l, UM v. RP, P < 0·05) were increased. Numbers of rumen protozoa (1·6, 3·2, 2·7, 3·3 (s.e.d. 0·75) × 105 per ml, UM v. RP, P < 0·20) tended to be higher 2 h after feeding when RP rather than UM were given. However, hay DM intake (1050, 960, 960, 880 (s.e.d. 45·3) g/day, UM v. RP, P < 0·05), and microbial protein supply (11·7, 9·3,11·1,10·8 (s.e.d. 0·59) g N per day, UM v. RP, P < 0·05), estimated from urinary purine excretion were reduced by feeding RP instead of UM.At the levels of inclusion tested RP did not increase the efficiency of rumen fermentation and were not as effective a supplement with urea as was molasses for a low-quality forage diet.

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