scholarly journals Adaptation Mechanisms of Yak (Bos grunniens) to High-Altitude Environmental Stress

Animals ◽  
2021 ◽  
Vol 11 (8) ◽  
pp. 2344
Author(s):  
Wondossen Ayalew ◽  
Min Chu ◽  
Chunnian Liang ◽  
Xiaoyun Wu ◽  
Yan Ping
Keyword(s):  
Environmental Stress ◽  
High Altitude ◽  
Genetic Basis ◽  
Genetic Characteristics ◽  
Term Selection ◽  
Bos Grunniens ◽  
The People ◽  
Morphological Adaptations ◽  
Representative Model

Living at a high altitude involves many environmental challenges. The combined effects of hypoxia and cold stress impose severe physiological challenges on endothermic animals. The yak is integral to the livelihood of the people occupying the vast, inhospitable Qinghai–Tibetan plateau and the surrounding mountainous region. Due to long-term selection, the yak exhibits stable and unique genetic characteristics which enable physiological, biochemical, and morphological adaptations to a high altitude. Thus, the yak is a representative model for mammalian plateau-adaptability studies. Understanding coping mechanisms provides unique insights into adaptive evolution, thus informing the breeding of domestic yaks. This review provides an overview of genetic adaptations in Bos grunniens to high-altitude environmental stress. Combined genomics and theoretical advances have informed the genetic basis of high-altitude adaptations.

Socioeconomic Challenges faced by Basin’s People in India

Think India ◽  
2019 ◽  
Vol 22 (2) ◽  
pp. 296-304
Author(s):  
Biplab Tripathy ◽  
Tanmoy Mondal
Keyword(s):  
River Basin ◽  
High Tide ◽  
North East ◽  
The People ◽  
Term Basis ◽  
Major River ◽  
River Ganga ◽  
Basin Region ◽  
Basin Area

India is a subcontinent, there huge no of people lived in river basin area. In India there more or less 80% of people directly or indirectly depend on River. Ganga, Brahamputra in North and North East and Mahanadi, Govabori, Krishna, Kaveri, Narmoda, Tapti, Mahi in South are the major river basin in India. There each year due to flood and high tide lots of people are suffered in river basin region in India. These problems destroy the socio economic peace and hope of the people in river basin. There peoples are continuously suffered by lots of difficulties in sort or in long term basis. Few basin regions are always in high alert at the time of monsoon seasons. Sometime due to over migration from basin area, it becomes empty and creates an ultimate loss of resources in India and causes a dis-balance situation in this area.

NEW VARIETIES OF CURRANTS AND GOOSEBERRY BREEDING PLANTS

1970 ◽  
pp. 41-46
Author(s):  
O. D. Golyaeva ◽  
O. V. Kurashev ◽  
S. D. Knyazev ◽  
А. Yu. Bakhotskaya
Keyword(s):  
Powdery Mildew ◽  
Genetic Basis ◽  
Black Currant ◽  
Leaf Spots ◽  
Agricultural Sciences ◽  
Berry Crops ◽  
New Varieties ◽  
First Time ◽  
Red Currant

The main goal of the scientific institution was and remains to improve the assortment of fruit and berry crops for the development of domestic horticulture. Black currant breeding at VNIISPK was started by A.F Tamarova and continued by the doctor of agricultural Sciences T.P.Ogoltsova and doctor of agricultural Sciences S.D. Knyazev. A long-term breeding program has been developed. The main goals of the program are to create black currant cultivars with continuous resistance to diseases, first of all powdery mildew, as wells resistance to pests, i.e. bud mite. As a result of the long-term work, over 40 black currant cultivars have been developed, 14 of them are zoned. Red currant breeding was led by the candidate of agricultural Sciences L.V. Bayanova; since 2001 the work has been continued by the candidate of agricultural Sciences O.D. Golyaeva. ‘Heinemanns Rote Spӓtlese’, the descendant of R. multiflorum Kit., was involved in the red currant breeding for the first time in Russia. On its genetic basis, a series of late maturing cultivars with long and dense racemes was created. At the Institute, in total 21cultivars of red currants have been developed, 13 of them are zoned. At present, red currant cultivars make up 25.5% of the zoned assortment in Russia. The first research on gooseberries was stated by V.P. Semakin and A.F Tamarova; since 1992 the systematic gooseberry breeding has been carried out by the candidate of agricultural Sciences O.V. Kurashev. On the basis of Grossularia robusta, we have created gooseberry forms that are resistant to powdery mildew and leaf spots. These forms are highly productive, weakly thorned, having bush habit suitable for mechanized harvest. The result of breeding activities was the transfer of 6 gooseberry cultivars to State agricultural testing: ‘Solnechny Zaychik’, ‘Nekrasovsky’, ‘Yupiter’, ‘Zemlianichny’, ‘Moryachok’ and ‘Discovery’.

A Study of Exposure of Overall Background Radiation In Syangja District of Nepal

2017 ◽  
pp. 92-95
Author(s):  
T Timilsina ◽  
K. R. Poudel ◽  
P. R. Poudel
Keyword(s):  
High Altitude ◽  
Background Radiation ◽  
Significant Risk ◽  
Total Radiation ◽  
Radiation Level ◽  
The People ◽  
Public Exposure

This study presents general exposure of background radiation to the people living or visiting nine places of Syangja district. A portable GM counter was used to quantify the total radiation at those places. The findings of this study show variation of radiation level at different places. Comparatively large values of radiation counts are observed at high altitude places (Gurung Dada: 70.23 cpm and Pokhari Dada: 64.77 cpm). The value of radiation count inside room is comparatively larger than that at outside room for these places. Moreover, small value of radiation count is observed at river side (Bank of Aandhikhola river: 21.63 cpm). Little large values are observed near Saligram stones and ancient statue than at other regions of one historical/religious place. Hence, results show fluctuations of background radiation level for different places. Some places have comparatively large value of radiation count while some places have comparatively small value. But there is no any abnormal value of radiation counts for all sample places. So there is, generally, no significant risk of public exposure to the background radiation for sample places.The Himalayan Physics Vol. 6 & 7, April 2017 (92-95)

Etude de l'aménagement d'une forêt classée au Mali avec la participation des populations riveraines - Données du problème et éléments de méthodologie | A Study of the Management of a State-Owned Forest in Mali with the Participation of the Population Living nearby - Issue under Investigation and Elements of Methodology

2000 ◽  
Vol 151 (3) ◽  
pp. 80-83
Author(s):  
Pascal Schneider ◽  
Jean-Pierre Sorg
Keyword(s):  
Natural Resources ◽  
Research Methodology ◽  
Large Scale ◽  
Environmental Context ◽  
Forest Resources ◽  
The State ◽  
Commercial Use ◽  
Economic Context ◽  
The People

In and around the state-owned forest of Farako in the region of Sikasso, Mali, a large-scale study focused on finding a compromise allowing the existential and legitimate needs of the population to be met and at the same time conserving the forest resources in the long term. The first step in research was to sketch out the rural socio-economic context and determine the needs for natural resources for autoconsumption and commercial use as well as the demand for non-material forest services. Simultaneously, the environmental context of the forest and the resources available were evaluated by means of inventories with regard to quality and quantity. According to an in-depth comparison between demand and potential, there is a differentiated view of the suitability of the forest to meet the needs of the people living nearby. Propositions for a multipurpose management of the forest were drawn up. This contribution deals with some basic elements of research methodology as well as with results of the study.

Endemic wheats of China as resources for breeding

2019 ◽  
pp. 11-25
Author(s):  
Hao Fu ◽  
N. P. Goncharov
Keyword(s):  
Sea Level ◽  
Triticum Aestivum L ◽  
Careful Study ◽  
Male Sterile ◽  
Important Place ◽  
Genetic Characteristics ◽  
The People ◽  
Spring Variety ◽  
Northern Border ◽  
Historical Heritage

Aim. To present the wheat endemics of China as source material for breeding and historical heritage. Results and Discussion. Wheat in China is the second most widely distributed cereal crop after rice. It is cultivated in China from the extreme northern border to the southern one, at altitudes from 154 m below sea level to 4450 m above sea level. The Chinian wheat is originated from South-West and West Asia and has a history of more than 2.8 thousand years. Since ancient times, the wheat species have been grown in China: bread (Triticum aestivum L.), compactum (T. compactum Host), polonicum (T. polonicum L.), turgidum (T. turgidum L.), durum (T. durum Desf.), turanian (T. turanicum Jakubz.). The Chinese ancient bread wheats are of interest for breeders because presence among them of early ripening, multi-flowering with the grain number in a spikelet up to 7-8 and in the ear up to 90-100, drought and winter hardy, resistant to powdery mildew and leaf rust; forms with good crossability with rye and Aegilops species. Among the endemic Chinese wheat, an important place belongs to the Chinese Spring variety which played an outstanding role in wheat genetics; super dwarfs Tom Pouce and Tibetan Dwarf; three-grain wheat, in which 3 grains are formed in one flower; Charklyk ancient wheat – a boneless form of polonicum wheat; dwarf blue wheat turgidum – with a strong waxy coating; Taigu-Male-Sterile Wheat – with gene male sterility; a wheats having species and subspecies status: wheat of Petropavlovskyi – Triticum petropavlovskyi Udacz. et Migusch.; Tibetan wheat – T. spelta L. ssp. tibetanum (Shao) N.P. Gontsch comb. nov .; Yunnan wheat – T. spelta L. ssp. yunnanse (King ex S.L. Chen) N.P. Gontsch comb. nov. The origin and genetic characteristics of China's endemic wheats are discussed. Conclusions. China's wheat endemics need careful study and conservation as a reserve of valuable genes and their complexes for breeding, and as an embodiment of the history, culture, talent and work of the people who created them, and an integral part of human cultural heritage.

Populism and Liberal Democracy

2019 ◽  
Author(s):  
Takis S. Pappas
Keyword(s):  
United States ◽  
Liberal Democracy ◽  
The United States ◽  
Comprehensive Theory ◽  
The People ◽  
Original Definition ◽  
Key Issues ◽  
Great Relevance ◽  
Definition Of

Based on an original definition of modern populism as “democratic illiberalism” and many years of meticulous research, Takis Pappas marshals extraordinary empirical evidence from Argentina, Greece, Peru, Italy, Venezuela, Ecuador, Hungary, the United States, Spain, and Brazil to develop a comprehensive theory about populism. He addresses all key issues in the debate about populism and answers significant questions of great relevance for today’s liberal democracy, including: • What is modern populism and how can it be differentiated from comparable phenomena like nativism and autocracy? • Where in Latin America has populism become most successful? Where in Europe did it emerge first? Why did its rise to power in the United States come so late? • Is Trump a populist and, if so, could he be compared best with Venezuela’s Chávez, France’s Le Pens, or Turkey’s Erdoğan? • Why has populism thrived in post-authoritarian Greece but not in Spain? And why in Argentina and not in Brazil? • Can populism ever succeed without a charismatic leader? If not, what does leadership tell us about how to challenge populism? • Who are “the people” who vote for populist parties, how are these “made” into a group, and what is in their minds? • Is there a “populist blueprint” that all populists use when in power? And what are the long-term consequences of populist rule? • What does the expansion, and possibly solidification, of populism mean for the very nature and future of contemporary democracy? Populism and Liberal Democracy will change the ways the reader understands populism and imagines the prospects of liberal democracy.

scholarly journals A Study of UVER in Santiago, Chile Based on Long-Term In Situ Measurements (Five Years) and Empirical Modelling

Energies ◽  
2021 ◽  
Vol 14 (2) ◽  
pp. 368
Author(s):  
Lisdelys González-Rodríguez ◽  
Amauri Pereira de Oliveira ◽  
Lien Rodríguez-López ◽  
Jorge Rosas ◽  
David Contreras ◽  
...  
Keyword(s):  
Urban Areas ◽  
Solar Spectrum ◽  
Sun Exposure ◽  
Great Accuracy ◽  
In Situ Measurements ◽  
Uv Index ◽  
Empirical Modelling ◽  
The People

Ultraviolet radiation is a highly energetic component of the solar spectrum that needs to be monitored because is harmful to life on Earth, especially in areas where the ozone layer has been depleted, like Chile. This work is the first to address the long-term (five-year) behaviour of ultraviolet erythemal radiation (UVER) in Santiago, Chile (33.5° S, 70.7° W, 500 m) using in situ measurements and empirical modelling. Observations indicate that to alert the people on the risks of UVER overexposure, it is necessary to use, in addition to the currently available UV index (UVI), three more erythema indices: standard erythemal doses (SEDs), minimum erythemal doses (MEDs), and sun exposure time (tery). The combination of UVI, SEDs, MEDs, and tery shows that in Santiago, individuals with skin types III and IV are exposed to harmfully high UVER doses for 46% of the time that UVI indicates is safe. Empirical models predicted hourly and daily values UVER in Santiago with great accuracy and can be applied to other Chilean urban areas with similar climate. This research inspires future advances in reconstructing large datasets to analyse the UVER in Central Chile, its trends, and its changes.

4-Jahres-Update der Murano-Studie bestätigt den Stellenwert von Venetoclax in der 2. Therapielinie der CLL

2021 ◽  
pp. 77-79
Author(s):  
Maximilian Schmutz ◽  
Sebastian Sommer
Keyword(s):  
Response Rate ◽  
Residual Disease ◽  
Gene Mutations ◽  
Progression Free Survival ◽  
Lymphocytic Leukemia ◽  
Fixed Duration ◽  
Genetic Characteristics ◽  
Genomic Complexity ◽  
End Of Treatment

<b>Purpose:</b> In previous analyses of the MURANO study, fixed-duration venetoclax plus rituximab (VenR) resulted in improved progression-free survival (PFS) compared with bendamustine plus rituximab (BR) in patients with relapsed or refractory chronic lymphocytic leukemia (CLL). At the 4-year follow-up, we report long-term outcomes, response to subsequent therapies, and the predictive value of molecular and genetic characteristics. <b>Patients and methods:</b> Patients with CLL were randomly assigned to 2 years of venetoclax (VenR for the first six cycles) or six cycles of BR. PFS, overall survival (OS), peripheral-blood minimal residual disease (MRD) status, genomic complexity (GC), and gene mutations were assessed. <b>Results:</b> Of 389 patients, 194 were assigned to VenR and 195 to BR. Four-year PFS and OS rates were higher with VenR than BR, at 57.3% and 4.6% (hazard ratio [HR], 0.19; 95% CI, 0.14 to 0.25), and 85.3% and 66.8% (HR, 0.41; 95% CI, 0.26 to 0.65), respectively. Undetectable MRD (uMRD) at end of combination therapy (EOCT) was associated with superior PFS compared with low MRD positivity (HR, 0.50) and high MRD positivity (HR, 0.15). Patients in the VenR arm who received ibrutinib as their first therapy after progression (n = 12) had a reported response rate of 100% (10 of 10 evaluable patients); patients subsequently treated with a venetoclax-based regimen (n = 14) had a reported response rate of 55% (six of 11 evaluable patients). With VenR, the uMRD rate at end of treatment (EOT) was lower in patients with GC than in those without GC (<i>P</i> = 0.042); higher GC was associated with shorter PFS. Higher MRD positivity rates were seen with <i>BIRC3</i> and <i>BRAF</i> mutations at EOCT and with <i>TP53, NOTCH1, XPO1,</i> and <i>BRAF</i> mutations at EOT. <b>Conclusion:</b> Efficacy benefits with fixed-duration VenR are sustained and particularly durable in patients who achieve uMRD. Salvage therapy with ibrutinib after VenR achieved high response rates. Genetic mutations and GC affected MRD rates and PFS. <b>Trial registration:</b> ClinicalTrials.gov NCT02005471.

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