scholarly journals Factors Associated with Fatality in Ontario Thoroughbred Racehorses: 2003–2015

Animals ◽  
2021 ◽  
Vol 11 (10) ◽  
pp. 2950
Author(s):  
Peter Physick-Sheard ◽  
Amanda Avison ◽  
William Sears
Keyword(s):  
Health Program ◽  
Field Size ◽  
Large Field ◽  
Thoroughbred Racehorses ◽  
High Incidence ◽  
Rapid Accumulation ◽  
History Of ◽  
Young Horses ◽  
Work Events ◽  
Official Records

Ontario’s Alcohol and Gaming Commission records equine racing fatalities through its Equine Health Program. The present study examined all Thoroughbred fatalities from 2003 to 2015, inclusive, to identify associations. Official records and details of fatalities were combined in multivariable logistic regression modelling of 236,386 race work-events (433 fatalities), and 459,013 workout work-events (252 fatalities). Fatality rates were 2.94/1000 race starts (all fatalities) and 1.96/1000 (breakdowns only) with an overall rate of 2.61% or 26.1 fatalities/1000 horses. Comparison with published reports reveals rates to be high. Musculoskeletal injury was the predominant complaint and there was a high incidence of horses dying suddenly. Liability was high for young horses early in the season with a differential according to sex and whether a male horse was gelded. Horses undertaking repeated workouts had a higher liability and liability was higher in workouts for horses switching from dirt/synthetic to turf racing and for young horses in sprints. Race distance was not significant but high fatality rates in some large field, distance races combined with effects of age and workload identified groups at particular risk. As field size increased, fatality liability increased for early-finishing horses. Findings suggest jockey strategy could be an important factor influencing fatalities. Probability of fatality declined over the study period. Findings indicate that rapid accumulation of workload in animals early in their preparation is likely to be damaging. Fatality fell toward the end of a season and for horses with a long career history of successful performance; however, horses not exhibiting this robustness and staying power represent the population of greatest concern. Associations may be characterised as representing sources of stress, current or cumulative, and identifying at-risk animals on this basis may be as productive as targeting specific, discrete mechanisms suspected to contribute to individual fatalities.

A new approach to the logic of discovery

2007 ◽  
Vol 50 (1) ◽  
pp. 7-27
Author(s):  
Gerald Massey
Keyword(s):  
Modal Logic ◽  
Scientific Discovery ◽  
Traditional View ◽  
New Approach ◽  
Logic Of Discovery ◽  
Good Fortune ◽  
High Incidence ◽  
History Of ◽  
Deep Sense

Contending that the quest for a logic of scientific discovery was prematurely abandoned, the author lays down eight phenomena that such a logic or theory must explain: the banality of scientific discovery; the trainability of scientists; the high incidence of simultaneous discoveries; the ubiquity of relative novices; the fact of scientific genius; the barrenness of isolated workers; the incommensurability of concepts of successive theories; and the quasi-incorporation of old concepts, objects, and methods in successor theories, The author then presents a new theory or logic of discovery according to which discoveries are the termini of "tweak paths" generated when scientists "tinker" with the laws, concepts, methods, and instruments of a given theory. Tinkering and tweaking are illustrated by examples from many-valued and modal logic and from Darwinian biology. Through the history of planetary discovery, the accidental role played by luck or good fortune in some discoveries is explored, but the author emphasizes that in a deep sense serendipity is an in eliminable feature of all scientific discovery because scientists never know m advance whether their tweaks will lead to dead ends or to positive developments. The author's new theory of scientific discovery is shown to account for all eight explananda, ft also reveals science to be a more egalitarian enterprise than the traditional view of scientific discovery as ultimately inexplicable depicts it.

scholarly journals Evaluation of a school health program directed to children with history of high absence.

1975 ◽  
Vol 65 (4) ◽  
pp. 388-393 ◽  
Author(s):  
G V Long ◽  
C Whitman ◽  
M S Johansson ◽  
C A Williams ◽  
R W Tuthill
Keyword(s):  
School Health ◽  
Health Program ◽  
School Health Program ◽  
History Of

Purulent Otitis Media: Differences Between Populations in Different Environments

PEDIATRICS ◽  
1974 ◽  
Vol 53 (2) ◽  
pp. 135-136
Author(s):  
Patrick Manning ◽  
Mary Ellen Avery ◽  
Alan Ross
Keyword(s):  
Hearing Loss ◽  
Adverse Effects ◽  
Language Development ◽  
Otitis Media ◽  
Early Life ◽  
Educational Programs ◽  
Previous Issue ◽  
High Incidence ◽  
History Of ◽  
Tympanic Membranes

The paper by Kaplan and colleagues in a previous issue starts by emphasizing the unusually high incidence of otitis media among Eskimo children. Forty-one percent of their cohort of 489 Alaskan Eskimo children, followed for ten years, had perforations or scars of the tympanic membranes; significant hearing losses were present in 16% of the group. Among the 374 children with a history of otorrhea, 291 (78%) had their first attack before their second birthday. The adverse effects of hearing loss in early life on language development were underscored by the authors, who quite properly point out the need for special educational programs.

scholarly journals Risk factors for esophageal squamous cell carcinoma and its histological precursor lesions in China: a multicenter cross-sectional study

BMC Cancer ◽  
2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Chen Niu ◽  
Yong Liu ◽  
Jialin Wang ◽  
Yuqin Liu ◽  
Shaokai Zhang ◽  
...  
Keyword(s):  
Risk Factors ◽  
Squamous Cell Carcinoma ◽  
Esophageal Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Intraepithelial Neoplasia ◽  
Precursor Lesions ◽  
Unconditional Logistic Regression ◽  
High Incidence ◽  
History Of

Abstract Background Despite research efforts, the causative factors that contribute to esophageal squamous cell carcinoma (ESCC) in high-risk areas have not yet been understood. In this study, we, therefore, aimed to describe the risk factors associated with ESCC and its precursor lesions. Methods We performed an endoscopic examination of 44,857 individuals aged 40–69 years from five high incidence regions of China in 2017–2018. Participants were classified as 4 groups of normal control, esophagitis, low-grade intraepithelial neoplasia (LGIN) and high-grade intraepithelial neoplasia/esophageal squamous cell carcinoma (HGIN/ESCC) using an unconditional logistic regression determine risk factors. Results We identified 4890 esophagitis, 1874 LGIN and 437 HGIN/ESCC cases. Crude odds ratios (ORs) and adjusted odds ratios were calculated using unconditional logistic regression. Drinking well and surface water, salty diet, and positive family history of cancer were the common risk factors for esophagitis, LGIN and HGIN/ESCC. History of chronic hepatitis/cirrhosis was the greatest risk factor of esophagitis (adjusted OR 2.96, 95%CI 2.52–3.47) and HGIN/ESCC (adjusted OR 1.91, 95%CI 1.03–3.22). Pesticide exposure (adjusted OR 1.20, 95%CI 1.05–1.37) was essential risk factor of LGIN. Conclusions Among individuals aged 40–69 years in high incidence regions of upper gastrointestinal cancer, the results provided important epidemiological evidence for the prevention of different precancerous lesions of ESCC.

scholarly journals Ergonomic Design of Classroom Furnitures: Evaluation of Comfortability and Musculoskeletal Disorders

2021 ◽  
Author(s):  
Kojo Agyapong Afrifah ◽  
Mark Glalah
Keyword(s):  
Musculoskeletal Disorders ◽  
Previous History ◽  
Descriptive Statistics ◽  
Furniture Design ◽  
Kwame Nkrumah ◽  
Lower Back ◽  
High Incidence ◽  
History Of ◽  
Spss Software ◽  
Wooden Furniture

Background: Anthropometric studies are essential in furniture design to ensure comfortability and improved productivity of the users. Methods: Anthropometry of 407 from a population of 5601 students, and classroom furniture at Kwame Nkrumah University of Science and Technology were evaluated. Student’s comfortability and reported musculoskeletal disorders (MSDs) in using the furniture were assessed with two questionnaires. Participants who volunteered for the study were randomly selected and had no previous history of MSDs. Descriptive statistics of the collected data were analyzed using SPSS software. Results: The participant's aged ranged from 17 to 28 years, and mostly were female (61%). The fitness between student’s anthropometry and classroom furniture included underneath table height for the imported plastic furniture and chair seat depth and width, as well as underneath table height for the locally manufactured wooden furniture. We observed high incidence of MSDs, including upper back (71.40%), lower back (58.30%), neck (51.90%), joint (39.10%), shoulder (32%), knee (25.20%), and wrist (22.60%) pain. The prevalence of MSDs were higher in women than men. The majority of the students were uncomfortable with using the furnitures, and only 6.6% reported comfortable experience. Conclusion: Recommended dimensions for ergonomically designed furniture have been proposed to reduce MSDs in the students. It would improves student’s health, and promote comfortability.

scholarly journals Commissioning Measurements of Electron Beam Using Montecarlo Algorithm on Truebeam STx® and Compariaon with Clinac iX Linear Accelerator

2021 ◽  
Vol 229 ◽  
pp. 01041
Author(s):  
Kamal Saidi ◽  
Redouane El Baydaoui ◽  
Hanae El Gouach ◽  
Othmane Kaanouch ◽  
Mohamed Reda Mesradi
Keyword(s):  
Electron Beam ◽  
Electron Beams ◽  
Measured Data ◽  
University Hospital ◽  
Field Size ◽  
Large Field ◽  
Water Phantom ◽  
Depth Dose ◽  
International University ◽  
The Absolute

TrueBeam STx latest generation linear accelerators (linacs) installed at Sheikh Khalifa International University Hospital in Casablanca, Morocco. The aim of this is to present and compare the result of the Electron commissioning measurement on TrueBeam Stx and clinac iX installed at Sheikh Khalifa International University Hospital in Casablanca, Morocco. A compariaon of eMC calculations and measurements for TrueBeam Stx were evaluated. Dosimetric parameters are systematically measured using a large water phantom 3D scanning system MP3 Water Phantom (PTW, Freiburg, Germany). The data of the electron beams commissioning including depth dose curves for each applicator, depth dose curves without applicator and the profile in air for a large field size 40x 40cm2, and the Absolute Dose (cGy/MU) for each applicator. All the data were examined and compared for five electron beams (E6MeV, E9MeV, E12MeV, E16MeV and E20MeV) of Varian’s TrueBeam STx and Clinac iX machines. A comparison, between measurement PDDs and calculated by the Eclipse electron Monte Carlo (eMC) algorithm were performed to validate Truebeam Stx commissioning. All this measurements were performed with a Roos and Markus plane parallel chamber. Our measured data indicated that electron beam PDDs from the TrueBeam Stx machine are well matched to those from our Varian Clinac iX machine. Significant differences between TrueBeam and Clinac iX were found in in‐air profiles and open field output. Maximum depth dose for the TrueBeam Stx and Clinac iX for the following energies (6, 9, 12, 16, 20 MeV) are respectively (1.15; 1.89; 2.6; 3.1; and 2.35) and (1.24; 1.95; 2.70; 2.99 and 2.4cm). For the TrueBeam Stx and Clinac iX the quality index R50 for applicator 15x15 cm2 are in the tolerance intervals. Surface dose increases by increasing energy for both machines. The Absolute Dose (cGy/MU) calibrated for both machine in Dmax at 1cGy/MU for the reference field size cone 15x15 cm2. Bremsstrahlung tail Rp per energy levels as follows for the TrueBeam Stx : 6 MeV – 2.85 cm, 9 MeV – 4.28 cm, 12 MeV – 5.97 cm, 16 MeV – 7.88 cm and 20 MeV – 9.86 cm. and for the Clinac iX : 6 MeV – 2.86 cm, 9 MeV – 4.32 cm, 12 MeV – 5.96 cm, 16 MeV – 7.93 cm and 20 MeV – 10.08 cm. A good agreement between modeled and measured data is observed.

Bladder Condyloma Acuminatum, A Case Report

2020 ◽  
pp. 1-3
Author(s):  
Villalba Bachur Roberto ◽  
◽  
Spagnuolo Juan Ignacio ◽  
Cora Florencia ◽  
◽  
...  
Keyword(s):  
Cervical Carcinoma ◽  
Hpv Infection ◽  
Cancer Case ◽  
World Population ◽  
Single Episode ◽  
Papilloma Virus ◽  
High Incidence ◽  
Bladder Cancer Case ◽  
History Of ◽  
Laser Enucleation

Background: Human Papilloma virus (HPV) infection is a high incidence entity in the world population. It is highly related to cervical carcinoma, as well as anogenital carcinoma, among others. The presences of bladder HPV lesions are infrequent and there is an association between it and the development of bladder cancer. Case presentation: We present a case of bladder HPV in a woman with a cervical carcinoma history that was presented clinically as a single episode of gross hematuria. We performed a cystoscopy and Holmium laser enucleation of the bladder tumors. Conclusion: We highlight the importance of consider HPV as a differential diagnosis of a bladder tumor, mainly in patients with history of pathologies related with the virus.

Incidence of Mitral Valve Prolapse in Adolescent Scoliosis and Thoracic Hypokyphosis

PEDIATRICS ◽  
1982 ◽  
Vol 70 (3) ◽  
pp. 451-454
Author(s):  
Stephen S. Hirschfeld ◽  
Charles Rudner ◽  
Clyde L. Nash ◽  
Eliezer Nussbaum ◽  
Eleanor M. Brower
Keyword(s):  
Family History ◽  
Mitral Valve ◽  
Mitral Valve Prolapse ◽  
Soft Tissue Defect ◽  
Skeletal Abnormality ◽  
Degree Relative ◽  
Familial History ◽  
High Incidence ◽  
History Of ◽  
Echocardiographic Evidence

Seventy-four patients with adolescent scoliosis underwent cardiac examination and M-mode echocardiography to detect the presence of mitral valve prolapse (MVP). Twenty-one (28%) had echocardiographic evidence of MVP, whereas 18 had auscultatory findings of a nonejection click or late systolic murmur. A subset of 41 patients had a family history of scoliosis and 37% had MVP. The incidence of MVP increased to 41% when a first degree relative, such as a sibling, parent, or offspring, had scoliosis. Thirty-six patients with scoliosis had additional thoracic hypokyphosis (straight back) and 13 (36%) had MVP. The incidence of MVP was 48% when the scoliosis and hypokyphosis were hereditary and increased to 53% when a familial history of skeletal abnormality was present. This study indicates a high incidence of MVP in patients with scoliosis and hypokyphosis, especially when the skeletal abnormality is familial. It suggests that the cardiac and skeletal systems may be affected by a generalized soft-tissue defect.

Incidence and risk factors for dysglycaemia in Asian-Indians: a 10-year population-based prospective cohort study

2021 ◽  
pp. postgradmedj-2021-141243
Author(s):  
Rahul Gupta ◽  
Satyam Singh Jayant ◽  
Ashu Rastogi ◽  
Sanjay K Bhadada ◽  
Anil Bhansali ◽  
...  
Keyword(s):  
Risk Factors ◽  
Asian Indians ◽  
Sedentary Lifestyle ◽  
Population Based ◽  
Incidence Rates ◽  
Study Cohort ◽  
Family History Of Diabetes ◽  
High Incidence ◽  
History Of ◽  
East Asia Region

BackgroundDiabetes prevalence estimates suggest an increasing trend in South-East Asia region, but studies on its incidence are limited. The current study aims to estimate the incidence of type 2 diabetes and pre-diabetes in a population-based cohort from India.MethodsA subset of Chandigarh Urban Diabetes Study cohort (n=1878) with normoglycaemia or pre-diabetes at baseline was prospectively followed after a median of 11 (0.5–11) years. Diabetes and pre-diabetes were diagnosed as per WHO guidelines. The incidence with 95% CI was calculated in 1000 person-years and Cox proportional hazard model was used to find the association between the risk factors and progression to pre-diabetes and diabetes.ResultsThe incidence of diabetes, pre-diabetes and dysglycaemia (either pre-diabetes or diabetes) was 21.6 (17.8–26.1), 18.8 (14.8–23.4) and 31.7 (26.5–37.6) per 1000 person-years, respectively. Age (HR 1.02, 95% CI 1.01 to 1.04), family history of diabetes (HR 1.56, 95% CI 1.09 to 2.25) and sedentary lifestyle (HR 1.51, 95% CI 1.05 to 2.17) predicted conversion from normoglycaemia to dysglycaemia, while obesity (HR 2.43, 95% CI 1.21 to 4.89) predicted conversion from pre-diabetes to diabetes.ConclusionA high incidence of diabetes and pre-diabetes in Asian-Indians suggests a faster conversion rate to dysglycaemia, which is partly explained by sedentary lifestyle and consequent obesity in these individuals. The high incidence rates call for a pressing need for public health interventions targeting modifiable risk factors.

Situating Tribes in History: Lessons from the Archives and the Social Sciences

2021 ◽  
Vol 53 (3) ◽  
pp. 473-476
Author(s):  
Nadav Samin
Keyword(s):  
Social Sciences ◽  
Twentieth Century ◽  
Middle East ◽  
Middle Eastern ◽  
Record Keeping ◽  
Know How ◽  
The Social ◽  
History Of ◽  
The Many ◽  
Official Records

The tribe presents a problem for the historian of the modern Middle East, particularly one interested in personalities, subtleties of culture and society, and other such “useless” things. By and large, tribes did not leave their own written records. The tribal author is a phenomenon of the present or the recent past. There are few twentieth century tribal figures comparable to the urban personalities to whose writings and influence we owe our understanding of the social, intellectual, and political history of the modern Middle East. There is next a larger problem of record keeping to contend with: the almost complete inaccessibility of official records on the postcolonial Middle East. It is no wonder that political scientists and anthropologists are among the best regarded custodians of the region's twentieth century history; they know how to make creative and often eloquent use of drastically limited tools. For many decades, suspicious governments have inhibited historians from carrying out the duties of their vocation. This is one reason why the many rich and original new monographs on Saddam Hussein's Iraq are so important. If tribes are on the margins of the records, and the records themselves are off limits, then one might imagine why modern Middle Eastern tribes are so poorly conceived in the scholarly imagination.

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