scholarly journals Effects of the Physiological Status and Diet on Blood Metabolic Parameters in Amiata Dairy Donkeys

Animals ◽  
2021 ◽  
Vol 11 (11) ◽  
pp. 3292
Author(s):  
Federica Salari ◽  
Cristina Roncoroni ◽  
Iolanda Altomonte ◽  
Carlo Boselli ◽  
Giovanni Brajon ◽  
...  
Keyword(s):  
Milk Fat ◽  
De Novo ◽  
Metabolic Parameters ◽  
Physiological Status ◽  
Weight Changes ◽  
Milk Fatty Acids ◽  
Grass Hay ◽  
Ad Libitum ◽  
Positive Correlations ◽  
Measurement Period

Body weight changes and blood metabolic parameters in jennies feeding two different diets and in three physiological statuses were investigated (maintenance vs. pregnancy; maintenance vs. lactation). The relationships between blood metabolic profile and milk quality were also evaluated. Fourteen jennies were allocated to two groups (1: pregnant/lactating; 2: non-pregnant, non–lactating). Pregnant jennies and maintenance jennies (during the first 10-week measurement period) fed a diet consisted of ad libitum grass hay (diet 1); lactating jennies and maintenance jennies (during the last 10-week measurement period) fed ad libitum grass hay plus 2 kg/head/day of concentrate (diet 2). Blood sampling was performed on the jennies of both groups; individual milk samples were also collected during the first 70 days in milk. Higher blood NEFA (p < 0.05) were found in pregnant compared to maintenance jennies (diet 1) (68 vs. 37 µmol/L). Lactating jennies showed higher (p < 0.01) average blood NEFA (268 vs. 26 µmol/L) and glucose (66 vs. 55 mg/dL) compared to the maintenance (diet 2). Blood glucose was positively correlated to milk fat (p < 0.05), while negative significant correlations between de novo milk fatty acids and NEFAs were observed. Positive correlations between plasma B-HBA and somatic cell count (p < 0.01) were also found.

Synthesis of milk fat from β-hydroxybutyrate and acetate in lactating goats

1974 ◽  
Vol 41 (2) ◽  
pp. 175-191 ◽  
Author(s):  
G. H. Smith ◽  
S. McCarthy ◽  
J. A. F. Rook
Keyword(s):  
Fatty Acids ◽  
Blood Plasma ◽  
Milk Fat ◽  
Direct Evidence ◽  
De Novo ◽  
Jugular Vein ◽  
Hydroxybutyric Acid ◽  
Milk Fatty Acids ◽  
Fatty Acid Chain ◽  
Lactating Goats

SummaryThe relative importance of β-hydroxybutyric acid (BHBA) and acetate as precursors for milk-fat synthesis was studied in lactating goats by infusing separately tracer quantities of [3−14C]DL-BHBA and [1−14C]acetate into the jugular vein, and [1−14C]butyrate into the portal vein. The concentrations and specific radioactivities of blood plasma constituents, the yields and specific radioactivities of individual milk fatty acids and the relative radioactivities of individual carbon atoms of milk fatty acids were determined.The infusion of [1−14C]butyrate resulted in the appearance of labelled BHBA in the blood plasma which behaved almost identically with infused [14C]BHBA as a precursor for milk fatty acids.The relative radioactivity of carbon atoms of the fatty acids of milk fat following the infusions provided direct evidence that BHBA had provided an intact 4-carbon unit at the methyl end of each fatty-acid chain. Acetate provided 2-carbon units both for the elongation of the 4-carbon units and for complete de novo synthesis. BHBA also provided 2-carbon units which behaved in a similar fashion to those from acetate.Acetate and BHBA together accounted for all of the C4–C12 acids of milk fat, about 75% of the C14, 45% of the C16 and 10% of the C18.The total contributions of the various precursors to the fatty acids of milk fat were: acetate 42%, BHBA 9·4% and other plasma precursors (by difference) 48·6%.

The effect of feeding in early lactation on feed intake, yields of milk, fat and protein and on live-weight change over one lactation cycle in dairy cows

1984 ◽  
Vol 103 (3) ◽  
pp. 629-637 ◽  
Author(s):  
C. L. Johnson
Keyword(s):  
Feed Intake ◽  
Weight Change ◽  
Milk Fat ◽  
Live Weight ◽  
Early Lactation ◽  
Weight Changes ◽  
Potential Yield ◽  
Energy Deficiency ◽  
Ad Libitum ◽  
Lactation Cycle

SummaryAn experiment has been made to study the effect of level of feeding in early lactation on the feed intake, yields of milk, fat and protein and on live-weight change over one lactation cycle. Adult British Friesian cows of high potential yield were randomly allocated to high (HP) or moderate (MP) levels of feeding for 20 weeks. They were then randomly allocated within treatments to controlled or ad libitum levels of feeding for the rest of the lactation.There were significant effects of feeding in the early part of lactation on the yields of milk, protein and lactose but not on milk fat or live-weight change. Cows on the MP treatment produced about 450 kg milk from body energy reserves but were unable to supplement fully the dietary energy deficiency. There was no significant response to feeding ad libitum in the second part of lactation and the differences in yields established in the first part were maintained in the second. There was no relationship between feed intake and milk yield for cows fed ad libitum nor did the level of feeding in early lactation influence the level of intake in the later part.There was little agreement between calculated energy balance and the live-weight changes but there was more between live-weight change and condition score.

Additive effects oftrans-10,cis-12 conjugated linoleic acid and propionic acid on milk fat content and composition in dairy cows

2010 ◽  
Vol 77 (3) ◽  
pp. 295-301 ◽  
Author(s):  
Gaëlle Maxin ◽  
Frédéric Glasser ◽  
Henri Rulquin
Keyword(s):  
Linoleic Acid ◽  
Dairy Cows ◽  
Conjugated Linoleic Acid ◽  
Propionic Acid ◽  
Milk Fat ◽  
De Novo ◽  
Fat Content ◽  
Experimental Conditions ◽  
Milk Fatty Acids ◽  
End Products

Diet is a relatively simple way to modify milk fat yield and composition in dairy cows as the end-products of digestion are precursors or inhibitors of milk fat synthesis. The individual effects of these end-products are well-known, but it is still not known whether these nutrients have an additive effect or an interaction effect on milk fat secretion. Thus our objective was to investigate the effects of two of these nutrients on milk fat secretion,trans-10,cis-12 conjugated linoleic acid (CLA) and propionic acid (C3) supplied alone or together, under the same experimental conditions. Four Holstein dairy cows were used in a 4×4 Latin square design with 14-d periods. Treatments were control, CLA (duodenal infusion of 1·85 g/d oftrans-10,cis-12 CLA), C3 (ruminal infusion of 500 g/d of C3) and CLA+C3 (duodenal infusion of 1·85 g/d oftrans-10,cis-12 CLA plus ruminal infusion 500 g/d of C3). Infusions oftrans-10,cis-12 CLA reduced milk fat content and yield by 18% whereas C3 infusions had no significant effect on milk fat secretion.Trans-10,cis-12 CLA decreased the yields of all milk fatty acids (FA). This reduction was proportionally greater for FA synthesized de novo than for preformed long-chain FA. Infusions of C3 decreased the yields and percentages of 4:0 and 18:0 and increased the yields and percentages of all odd-chain FA. Interactions betweentrans-10,cis-12 CLA and C3 infusions on milk fat content, yield and FA composition were never significant. Overall, this study showed thattrans-10,cis-12 CLA has different and greater effects on milk fat secretion than C3. Moreover, under our experimental conditions, their effects on milk FA yields, which reflect their effects on mammary lipogenesis, were additive, whatever their individual effect.

scholarly journals Milk Fatty Acid Profiles in Different Animal Species: Focus on the Potential Effect of Selected PUFAs on Metabolism and Brain Functions

Nutrients ◽  
2021 ◽  
Vol 13 (4) ◽  
pp. 1111
Author(s):  
Maria P. Mollica ◽  
Giovanna Trinchese ◽  
Fabiano Cimmino ◽  
Eduardo Penna ◽  
Gina Cavaliere ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Human Health ◽  
Milk Fat ◽  
Animal Species ◽  
Essential Fatty Acids ◽  
In Vivo Studies ◽  
Omega 3 ◽  
Milk Fatty Acids ◽  
Brain Functions ◽  
The Impact

Milk contains several important nutrients that are beneficial for human health. This review considers the nutritional qualities of essential fatty acids (FAs), especially omega-3 (ω-3) and omega-6 (ω-6) polyunsaturated fatty acids (PUFAs) present in milk from ruminant and non-ruminant species. In particular, the impact of milk fatty acids on metabolism is discussed, including its effects on the central nervous system. In addition, we presented data indicating how animal feeding—the main way to modify milk fat composition—may have a potential impact on human health, and how rearing and feeding systems strongly affect milk quality within the same animal species. Finally, we have presented the results of in vivo studies aimed at supporting the beneficial effects of milk FA intake in animal models, and the factors limiting their transferability to humans were discussed.

PRELIMINARY EVALUATION OF THE ADDITION OF GLUCOGENIC MATERIALS TO THE RATIONS OF LACTATING COWS

1971 ◽  
Vol 51 (3) ◽  
pp. 721-727 ◽  
Author(s):  
L. J. FISHER ◽  
J. D. ERFLE ◽  
F. D. SAUER
Keyword(s):  
Fatty Acids ◽  
Propylene Glycol ◽  
Milk Fat ◽  
Volatile Fatty Acids ◽  
Rumen Fluid ◽  
Preliminary Evaluation ◽  
Early Lactation ◽  
Lactating Cows ◽  
Ad Libitum ◽  
Beta Hydroxybutyrate

Glutamate, succinate, propylene glycol, or glycerol were added to a basic concentrate at 3.3% of air-dry feed. Each concentrate was fed both ad libitum and in restricted amounts to four cows in early lactation. Dietary intake, milk yield and composition, molar proportions of rumen volatile fatty acids and blood glucose, ketones and plasma free fatty acids were used as criteria of effect of these supplements. Propylene glycol in the diet resulted in a lower intake of concentrate compared with glycerol (11.44 versus 14.30 kg/day) and significantly decreased (P < 0.05) rumen butyrate and plasma beta-hydroxybutyrate. Glutamate supplementation prevented the fall in milk fat content which occurred when the other three supplemented concentrates were fed ad libitum, and this effect may have been related to the constancy in the ratio of acetate to propionate in the rumen fluid.

Nutritive value of Albizia lebbek supplements for growing sheep

1992 ◽  
Vol 32 (3) ◽  
pp. 273 ◽  
Author(s):  
i Dwatmadj ◽  
E Teleni ◽  
AR Bird ◽  
JB Lowry
Keyword(s):  
Plasma Glucose ◽  
Nutritive Value ◽  
Environmental Temperature ◽  
Daily Maximum ◽  
Albizia Lebbeck ◽  
N Retention ◽  
Grass Hay ◽  
Ad Libitum ◽  
Dietary Treatments ◽  
Albizia Lebbek

This study was undertaken to evaluate the effect of supplements of siris (Albizia lebbeck) flowers and leaves on Merino wethers fed Mitchell grass hay (Astrebla spp.). Three groups, each of 6 sheep, were fed the following diets: hammermilled Mitchell grass hay ad libitum (M); M + 181 g DM/day of siris flowers (MF), and M + 216 g DM/day of siris leaves (ML). The experiment, conducted over 17 days, measured feed intake and digestibility, nitrogen (N) retention, and plasma glucose and urea concentrations. The total DM intakes by MF and ML sheep were significantly (P<0.01) higher than those in M sheep. As a result of the supplement of siris flowers, the digestibility of the MF diet was highest (P<0.01). Sheep fed the M diet showed negative N retention, while MF and ML sheep showed positive N retention. The increased (P<0.01) N retention in the MF and ML sheep was associated with increased (P<0.01) urinary N excretion. The improved nutritional state of MF and ML sheep was associated with increases in plasma glucose and urea concentrations. Environmental temperature, which reached a mean daily maximum of 31.3�C, did not interact with the dietary treatments.

Effect of physical processing on in situ degradation of barley in the caecum of ponies

1998 ◽  
Vol 1998 ◽  
pp. 127-127
Author(s):  
B M L McLean ◽  
J J Hyslop ◽  
A C Longland ◽  
D Cuddeford
Keyword(s):  
Sample Size ◽  
Dry Matter ◽  
Cereal Grains ◽  
Processing Methods ◽  
Grass Hay ◽  
Physical Processing ◽  
In Situ Degradation ◽  
Ad Libitum ◽  
Fixed Times

Cereal grains are often subjected to physical processing before being fed to equids. However, little information is available on how physical processing of cereals affects degradation dynamics in equids. This experiment examines the effect of two physical processing methods (micronisation and extrusion) on in situ degradation of barley in the caecum of poniesThree caecally fistulated mature Welsh-cross pony geldings (approx. LW 270kg) were offered ad libitum grass hay plus minerals. Incubation bags (monofilament polyester 6.5 x 20cm, 41μm pores, 16mg/cm2 sample size) containing either unprocessed barley (UB), micronised barley (MB) or extruded barley (EB) were incubated in the caecum for fixed times according to both a forward (0, 2, 4, 6, 12, 8, 24, 48h) and reverse (48, 24, 8, 4, 12, 6, 2, 0h) incubation sequence. For each feedstuff residues from each time were bulked within pony and across incubation sequence for subsequent analysis of dry matter (DM) and starch (STC). Degradation profiles were fitted to the DM and STC disappearance data according to Ørskov and McDonald (1979).

scholarly journals Spot 14: A Marker of Aggressive Breast Cancer and a Potential Therapeutic Target

Endocrinology ◽  
2006 ◽  
Vol 147 (9) ◽  
pp. 4048-4055 ◽  
Author(s):  
William B. Kinlaw ◽  
Jennifer L. Quinn ◽  
Wendy A. Wells ◽  
Christopher Roser-Jones ◽  
Joel T. Moncur
Keyword(s):  
Breast Cancer ◽  
Cancer Cells ◽  
Therapeutic Target ◽  
Milk Fat ◽  
Breast Cancer Cells ◽  
De Novo ◽  
Lipid Synthesis ◽  
Breast Cancers ◽  
Spot 14 ◽  
Aggressive Breast Cancer

Spot 14 (S14) is a nuclear protein that communicates the status of dietary fuels and fuel-related hormones to genes required for long-chain fatty acid synthesis. In mammary gland, S14 is important for both epithelial proliferation and milk fat production. The S14 gene is amplified in some breast cancers and is strongly expressed in most. High expression of S14 in primary invasive breast cancer is conspicuously predictive of recurrence. S14 mediates the induction of lipogenesis by progestin in breast cancer cells and accelerates their growth. Conversely, S14 knockdown impairs de novo lipid synthesis and causes apoptosis. We found that breast cancer cells do not express lipoprotein lipase (LPL) and hypothesize that they do not have access to circulating lipids unless the local environment supplies it. This may explain why primary breast cancers with low S14 do not survive transit from the LPL-rich mammary fat pad to areas devoid of LPL, such as lymph nodes, and thus do not appear as distant metastases. Thus, S14 is a marker for aggressive breast cancer and a potential target as well. Future effort will center on validation of S14 as a therapeutic target and producing antagonists of its action.

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