scholarly journals Phenolic Compounds in Calafate Berries Encapsulated by Spray Drying: Neuroprotection Potential into the Ingredient

Antioxidants ◽  
2021 ◽  
Vol 10 (11) ◽  
pp. 1830
Author(s):  
María E. Romero-Román ◽  
Mauricio Schoebitz ◽  
Jorge Fuentealba ◽  
Cristina García-Viguera ◽  
María D. López Belchí
Keyword(s):  
Spray Drying ◽  
Antioxidant Activities ◽  
Value Added ◽  
Cost Effective ◽  
Biological Action ◽  
Natural State ◽  
Degenerative Disorders ◽  
The Stability ◽  
Berry Extracts

Calafate is a berry rich in anthocyanins that presents higher content of polyphenols than other fruits. Its compounds have been described previously, however, the potential thereof in preventing and treating degenerative disorders has not yet been studied. Due to its astringency, the consumption of this berry in its natural state is limited. To profit from the aforementioned properties and reduce palatability issues, calafate berry extracts were microencapsulated by spray drying, a rapid, cost-effective and scalable process, and were then compared with freeze drying as a control. The stability of its contents and its in-vitro potential, with respect to AChE activity and neuroprotection, were measured from the obtained microcapsules, resulting from temperature treatments and different encapsulant contents. The results indicated that the spray-dried powders were stable, despite high temperatures, and their encapsulation exhibited nearly 50% efficiency. The highest quantity of polyphenols and 3-O-glycosylated anthocyanins was obtained from encapsulation with 20% maltodextrin, at 120 °C. Temperature did not affect the microcapsules’ biological action, as demonstrated by their antioxidant activities. The prevention of Aβ peptide cytotoxicity in PC12 cells (20%) revealed that encapsulated calafate can confer neuroprotection. We conclude that spray-drying is an appropriate technique for scaling-up and producing new value-added calafate formulations with anti-neurodegenerative effects and vivid colors.

scholarly journals Ramalin, a Novel Phenyl Hydrazide from the Lichen Ramalina Terebrata; Isolation, Total Synthesis and Biological Activities

2016 ◽  
Vol 30 (2) ◽  
pp. 35-42
Author(s):  
Durga Prasad Pandey ◽  
Hari Datta Bhattarai
Keyword(s):  
Total Synthesis ◽  
Antioxidant Activities ◽  
Biological Activities ◽  
Cost Effective ◽  
Scale Production ◽  
In Vivo Test ◽  
The Antarctic ◽  
Industrial Scale Production

Ramalin, a new L-glutamic acid derivative of phenylhydrazide (Y-glutamyl-N'-(2-hydroxyphenyl) hydrazide, 1) was isolated from the Antarctic lichen, Ramalina terebrata after a series of bioactivity guided fractionation of crude aqueous methanolic extract. Ramalin showed stronger antioxidant activities than commercially available standards, ascorbic acid, trolox, BHA, kojic acid in both, in vitro and in vivo test systems. In addition, ramalin showed no/less toxicity effects against two human cell lines; fibroblast (CCD-986SK) cells and keratinocyte (HaCaT). Thus, realign merits for cosmetic application and industrial scale production were needed. We developed a cost effective total synthesis of ramalin with 71.5% yield and described here.

Microencapsulation of Colors by Spray Drying - A Review

2012 ◽  
Vol 8 (2) ◽  
Author(s):  
Kannan Kandansamy ◽  
Priyenka Devi Somasundaram
Keyword(s):  
Spray Drying ◽  
Quality Indicator ◽  
Milk Protein ◽  
Cost Effective ◽  
Effective Technique ◽  
Food Ingredients ◽  
Natural Pigments ◽  
Natural Colorants ◽  
Cost Effective Technique ◽  
The Stability

Color is one of the important attributes of foods being considered as a quality indicator and determining frequently their acceptance. Many natural pigments like anthocyanin, lycopenes, betalains etc., are subjected to color loss during storage. Hence in order to increase the stability of the natural colorants the technology of microencapsulation is involved. Microencapsulation has been used in recent years for the encapsulation of food ingredients such as flavours, colors, lipids and milk protein. Among various methods used for microencapsulation of colors, the technically feasible and cost effective technique is spray drying. This paper reviews the various concepts of spray drying and various technologies involved in microencapsulation which are considered to be useful parameters for increasing the stability of natural colorants. It also summarizes the most commonly used natural colorants which can be encapsulated.

Phytochemical screening and potential of natural dye colourant from pomegranate (Punica granatum L.)

2016 ◽  
Vol 45 (1) ◽  
pp. 38-44 ◽  
Author(s):  
S. Mohajer ◽  
R.M. Taha ◽  
S.Z. Azmi
Keyword(s):  
Polyvinyl Alcohol ◽  
Antioxidant Activities ◽  
Punica Granatum ◽  
Natural Dye ◽  
Coating System ◽  
Content Type ◽  
Ic50 Values ◽  
The Stability

Purpose – The purpose of this paper is to identify the most dominant pigment of pomegranate explants for natural color coatings and detect the presence of phytochemical constituents and comparison of the antioxidant activities. Design/methodology/approach – Extracts of leaf, stem, peel and seed of in vitro and in vivo growth cultures were prepared for phytochemical constituent and antioxidant activity. The supernatant from 95 per cent methanol was mixed with 15 per cent polyvinyl alcohol (PVA) with the ratio of 1:1 to form a coating system. Findings – Although glycosides was not found in this species, tests for tannins and flavonoids were positive in all samples. The IC50 values were also comparable to commercial antioxidant ascorbic acid with 34.92 per cent inhibition. Chlorophyll a and b were detected in stem and leaf using UV-photospectrometer in 420 and 645 nm wavelengths ranges. The effects of heat and salt on the stability of natural dye colorants mixed with polyvinyl alcohol to form a basic coating system were indicated negatively in in vivo and in vitro growth cultures. Originality/value – The paper shows that further improvement with co-pigmentations may give a notable mixture from pomegranate extraction for the paint materials or nail varnish. It was also indicated that pomegranate contains some compounds such as polyphenolics that can donate electron/hydrogen easily.

scholarly journals Fabrication of Planar Microelectrode Array Using Laser-Patterned ITO and SU-8

Micromachines ◽  
2021 ◽  
Vol 12 (11) ◽  
pp. 1347
Author(s):  
Hee Soo Jeong ◽  
Seoyoung Hwang ◽  
Kyou Sik Min ◽  
Sang Beom Jun
Keyword(s):  
Indium Tin Oxide ◽  
Microelectrode Array ◽  
Cost Effective ◽  
Neural Recording ◽  
Different Types ◽  
Unique Approach ◽  
Impedance Monitoring ◽  
The Stability ◽  
Microfabrication Techniques

For several decades, microelectrode array (MEA) has been a powerful tool for in vitro neural electrophysiology because it provides a unique approach for monitoring the activity of a number of neurons over time. Due to the various applications of MEAs with different types of cells and tissues, there is an increasing need to customize the electrode designs. However, the fabrication of conventional MEAs requires several microfabrication procedures of deposition, etching, and photolithography. In this study, we proposed a simple fabrication method with a laser-patterned indium tin oxide (ITO) conductor and SU-8 photoresist insulation. Unlike in a conventional metal patterning process, only the outlines of ITO conductors are ablated by laser without removing background ITO. Insulation is achieved simply via SU-8 photolithography. The electrode sites are electroplated with iridium oxide (IrOX) to improve the electrochemical properties. The fabricated MEAs are electrochemically characterized and the stability of insulation is also confirmed by impedance monitoring for three weeks. Dissociated neurons of rat hippocampi are cultured on MEAs to verify the biocompatibility and the capacity for extracellular neural recording. The electrochemical and electrophysiological results with the fabricated MEAs are similar to those from conventional SiNX-insulated MEAs. Therefore, the proposed MEA with laser-patterned ITO and SU-8 is cost-effective and equivalently feasible compared with the conventional MEAs fabricated using thin-film microfabrication techniques.

Stability of phenolic content of some herbal infusions and their antioxidant activity following in vitro digestion

2017 ◽  
Vol 42 (4) ◽  
Author(s):  
Engin Celep ◽  
Selin Akyuz ◽  
Yigit İnan ◽  
Erdem Yesilada
Keyword(s):  
Antioxidant Activity ◽  
Phenolic Content ◽  
Antioxidant Activities ◽  
In Vitro Digestion ◽  
In Vitro Studies ◽  
Vast Number ◽  
The World ◽  
The Stability ◽  
Herbal Infusions

Abstract:Herbal infusions are among the most widely consumed beverages throughout the world. Their popularity arises due to not only their pleasant aroma and taste, but also their high phenolic content and antioxidant activity. A vast number of in vitro studies revealed their high phenolic content, together with strong antioxidant activity. However, the majority of them seem to ignore some important physiological parameters, such as bioavailability or bioaccessibility. The present study was planned to evaluate the stability of phenolic content and antioxidant activities of seven most widely preferred herbal infusions. A stimulated version of gastrointestinal infusion was added to the study for comparative purposes. The results indicated the loss of both phenolic content and antioxidant activity of herbal infusions after being submitted to digestion.

scholarly journals In Vitro Studies on the Relationship Between the Antioxidant Activities of Some Berry Extracts and Their Binding Properties to Serum Albumin

2014 ◽  
Vol 172 (6) ◽  
pp. 2849-2865 ◽  
Author(s):  
Jacek Namiesnik ◽  
Kann Vearasilp ◽  
Alina Nemirovski ◽  
Hanna Leontowicz ◽  
Maria Leontowicz ◽  
...  
Keyword(s):  
Serum Albumin ◽  
Antioxidant Activities ◽  
In Vitro Studies ◽  
Binding Properties ◽  
Berry Extracts ◽  
The Relationship

scholarly journals Evaluation of the Stability of the Total Antioxidant Capacity, Polyphenol Contents, and Starch Hydrolase Inhibitory Activities of Kombucha Teas Using anIn VitroModel of Digestion

2015 ◽  
Vol 2015 ◽  
pp. 1-9 ◽  
Author(s):  
Mindani I. Watawana ◽  
Nilakshi Jayawardena ◽  
Shakkya J. Ranasinghe ◽  
Viduranga Y. Waisundara
Keyword(s):  
Inhibitory Activity ◽  
Fermentation Process ◽  
Total Phenolics ◽  
Antioxidant Activities ◽  
Different Types ◽  
Total Antioxidant ◽  
Phenolics Content ◽  
Inhibitory Activities ◽  
The Stability

The objective of this study was to evaluate and compare antioxidant and starch hydrolase inhibitory activity of three different types of Kombucha beverages prepared by three pellicles with different microbial compositions. The fermentation process was carried out for 7 days and the assessments of antioxidant and starch hydrolase inhibitory activities as well as tea phenolic compounds were carried out. These parameters were also evaluated after subjecting the final fermented samples to gastric and duodenal digestion in anin vitrodigestion model. The pH had a statistically significant decrease during the period of fermentation. The total phenolics content and antioxidant activities had increased during the fermentation process as well as when subjected to digestion. The starch hydrolase inhibitory activities also increased in a similar manner during the different phases. Theα-amylase andα-glucosidase inhibitory activities showed statistically significant increases(P<0.05)as the fermentation progressed, while an increase was observed after being subjected to pancreatic and duodenal digestion as well. All three types of tea showed a higherα-amylase inhibitory activity thanα-glucosidase inhibitory activity.

scholarly journals Synthesis, Characterization and toxicity Analysis of Novel Silver Nanoparticles from Brassica oleracea var italica (Broccoli)

2020 ◽  
Vol 2 (1) ◽  
pp. 21
Keyword(s):  
Silver Nanoparticles ◽  
Electron Microscope ◽  
Brassica Oleracea ◽  
Vegetable Consumption ◽  
Antioxidant Activities ◽  
Nitrate Solution ◽  
Synthesis Method ◽  
Value Added ◽  
Anti Cancer

Epidemiologic studies demonstrate that vegetable consumption decreases the risk of various types of cancers. Crucifers were found to have anti-cancer and antioxidant activities due to their enriched content of glycosylates. Nanotechnology is the design, characterization, production & application of structures, devices, and systems by controlling shape and size at the nanoscale. This work describes a novel combinatorial synthesis approach, which is rapid and simple for the synthesis of metallic nanostructures of novel metals such as silver (Ag) by using a “comparison study of Conventional method (CM) and Microwave (MW) synthesis” method of silver nanoparticles. By the current study, we describe a cost-effective and environment-friendly technique for green synthesis of silver nanoparticles through the extract of Broccoli. AgNPs characterized using UV–Vis absorption spectroscopy was used to monitor the quantitative formation of silver nanoparticles. The characteristics features of the obtained silver nanoparticles were studied using a Scanning electron microscope (SEM), Transmission electron microscope (TEM), Fourier-transform infrared spectroscopy (FTIR). Here, we have reported a simple biological and low-cost approach for the preparation of stable silver nanoparticles by bioreduction of silver nitrate solution using Brassica oleracea (Broccoli) aqueous extract. The in-vitro analysis was performed in HEp 2 cell lines against which anti-cancer activity was recorded. Additionally, the antioxidant activity was also found by estimating the antioxidant enzymes. The in vivo toxicity was performed using chick embryos. The important outcome of the study will be the development of value-added products from cruciferous plants like B. oleracea for nanotechnology-based industries.

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