scholarly journals A Proposed In Vitro Methodology for Assessing the Accuracy of Three-Dimensionally Printed Dental Models and the Impact of Storage on Dimensional Stability

2021 ◽  
Vol 11 (13) ◽  
pp. 5994
Author(s):  
Li Hsin Lin ◽  
Joshua Granatelli ◽  
Frank Alifui-Segbaya ◽  
Laura Drake ◽  
Derek Smith ◽  
...  

The objective of this study was to propose a standardised methodology for assessing the accuracy of three-dimensional printed (3DP) full-arch dental models and the impact of storage using two printing technologies. A reference model (RM) comprising seven spheres was 3D-printed using digital light processing (MAX UV, MAX) and stereolithography (Form 2, F2) five times per printer. The diameter of the spheres (n = 35) represented the dimensional trueness (DT), while twenty-one vectors (n = 105) extending between the sphere centres represented the full-arch trueness (FT). Samples were measured at two (T1) and six (T2) weeks using a commercial profilometer to assess their dimensional stability. Significant (p < 0.05) contraction in DT occurred at T1 and T2 with a medium deviation of 108 µm and 99 µm for MAX, and 117 µm and 118 µm for F2, respectively. No significant (p > 0.05) deviations were detected for FT. The detected median deviations were evenly distributed across the arch for MAX at <50 µm versus F2, where the greatest error of 278 µm was in the posterior region. Storage did not significantly impact the model’s DT in contrast to FT (p < 0.05). The proposed methodology was able to assess the accuracy of 3DP. Storage significantly impacted the full-arch accuracy of the models up to 6 weeks post-printing.


2020 ◽  
Vol 9 (5) ◽  
pp. 1436 ◽  
Author(s):  
Tim Joda ◽  
Lea Matthisson ◽  
Nicola U. Zitzmann

The aim of this in vitro study was to analyze the impact of model aging on the accuracy of 3D-printed dental models. A maxillary full-arch reference model with prepared teeth for a three-unit fixed dental prosthesis was scanned ten times with an intraoral scanner (3Shape TRIOS Pod) and ten models were 3D printed (Straumann P-Series). All models were stored under constant conditions and digitized with a desktop scanner after 1 day; 1 week; and 2, 3, and 4 weeks. For accuracy, a best-fit algorithm was used to analyze the deviations of the abutment teeth (GFaI e.V Final Surface®). Wilcoxon Rank Sum Tests were used for comparisons with the level of significance set at α = 0.05. Deviation analysis of the tested models showed homogenous intragroup distance calculations at each timepoint. The most accurate result was for 1 day of aging (3.3 ± 1.3 µm). A continuous decrease in accuracy was observed with each aging stage from day 1 to week 4. A time-dependent difference was statistically significant after 3 weeks (p = 0.0008) and 4 weeks (p < 0.0001). Based on these findings, dental models should not be used longer than 3 to 4 weeks after 3D printing for the fabrication of definitive prosthetic reconstructions.



Materials ◽  
2021 ◽  
Vol 14 (20) ◽  
pp. 6185
Author(s):  
Seung-Ho Shin ◽  
Re-Mee Doh ◽  
Jung-Hwa Lim ◽  
Jae-Sung Kwon ◽  
June-Sung Shim ◽  
...  

During the three-dimensional (3D) printing process of a dental prosthesis, using photopolymer resin, partially polymerized resin is further cured through the postcuring process that proceeds after the printing, which improves the stability of the printed product. The mechanical properties of the end product are known to be poor if the postcuring time is insufficient. Therefore, this study evaluated the effect of the postcuring time of the 3D-printed denture base on its dimensional stability, according to the aging period. The 3D prints were processed after designing maxillary and mandibular denture bases, and after the following postcuring times were applied: no postcuring, and 5, 15, 30, and 60 min. The dimensional stability change of the denture base was evaluated and analyzed for 28 days after the postcuring process. The trueness analysis indicated that the mandibular denture base had lower output accuracy than the maxillary denture base, and the dimensional stability change increased as postcuring progressed. In the no postcuring group for the mandible, the error value was 201.1 ± 5.5 µm (mean ± standard deviation) after 28 days, whereas it was 125.7 ± 13.0 µm in the 60 min postcuring group. For both the maxilla and the mandible, shorter postcuring times induced larger dimensional stability changes during the aging process. These findings indicate that in order to manufacture a denture base with dimensional stability, a sufficient postcuring process is required during the processing stage.



Materials ◽  
2019 ◽  
Vol 12 (21) ◽  
pp. 3499 ◽  
Author(s):  
Jae-Won Choi ◽  
Jong-Ju Ahn ◽  
Keunbada Son ◽  
Jung-Bo Huh

The aim of this study was to evaluate the accuracy of dental models fabricated by conventional, milling, and three-dimensional (3D) printing methods. A reference model with inlay, single crown, and three-unit fixed dental prostheses (FDP) preparations was prepared. Conventional gypsum models (CON) were manufactured from the conventional method. Digital impressions were obtained by intraoral scanner, which were converted into physical models such as milled gypsum models (MIL), stereolithography (SLA), and digital light processing (DLP) 3D printed photopolymer models (S3P and D3P). Models were extracted as standard triangulated language (STL) data by reference scanner. All STL data were superimposed by 3D analysis software and quantitative and qualitative analysis was performed using root mean square (RMS) values and color difference map. Statistical analyses were performed using the Kruskal–Wallis test and Mann–Whitney U test with Bonferroni’s correction. For full arch, the RMS value of trueness and precision in CON was significantly smaller than in the other groups (p < 0.05/6 = 0.008), and there was no significant difference between S3P and D3P (p > 0.05/6 = 0.008). On the other hand, the RMS value of trueness in CON was significantly smaller than in the other groups for all prepared teeth (p < 0.05/6 = 0.008), and there was no significant difference between MIL and S3P (p > 0.05/6 = 0.008). In conclusion, conventional gypsum models showed better accuracy than digitally milled and 3D printed models.



2021 ◽  
Vol 11 (13) ◽  
pp. 6013
Author(s):  
Rebecca Jungbauer ◽  
Jonas Breunig ◽  
Alois Schmid ◽  
Mira Hüfner ◽  
Robert Kerberger ◽  
...  

The present study aimed to investigate the impact of hardness from 3D printed transfer trays and dental crowding on bracket bonding accuracy. Lower models (no crowding group: Little’s Irregularity Index (LII) < 3, crowding group: LII > 7, n = 10 per group) were selected at random, digitized, 3D printed, and utilized for semiautomated virtual positioning of brackets and tubes. Hard and soft transfer trays were fabricated with polyjet printing and digital light processing, respectively. Brackets and tubes were transferred to the 3D printed models and altogether digitized using intraoral scanning (IOS) and microcomputed tomography (micro-CT) for assessment of linear and angular deviations. Mean intra- and interrater reliability amounted to 0.67 ± 0.34/0.79 ± 0.16 for IOS, and 0.92 ± 0.05/0.92 ± 0.5 for the micro-CT measurements. Minor linear discrepancies were observed (median: 0.11 mm, Q1–Q3: −0.06–0.28 mm). Deviations in torque (median: 2.49°, Q1–Q3: 1.27–4.03°) were greater than angular ones (median: 1.81°, Q1–Q3: 1.05°–2.90°), higher for hard (median: 2.49°, Q1–Q3: 1.32–3.91°) compared to soft (median: 1.77°, Q1–Q3: 0.94–3.01°) trays (p < 0.001), and torque errors were more pronounced at crowded front teeth (p < 0.05). In conclusion, the clinician should carefully consider the potential impact of hardness and crowding on bracket transfer accuracy, specifically in torque and angular orientation.



2020 ◽  
Vol 6 (1) ◽  
pp. 57-69
Author(s):  
Amirhosein Fathi ◽  
Farzad Kermani ◽  
Aliasghar Behnamghader ◽  
Sara Banijamali ◽  
Masoud Mozafari ◽  
...  

AbstractOver the last years, three-dimensional (3D) printing has been successfully applied to produce suitable substitutes for treating bone defects. In this work, 3D printed composite scaffolds of polycaprolactone (PCL) and strontium (Sr)- and cobalt (Co)-doped multi-component melt-derived bioactive glasses (BGs) were prepared for bone tissue engineering strategies. For this purpose, 30% of as-prepared BG particles (size <38 μm) were incorporated into PCL, and then the obtained composite mix was introduced into a 3D printing machine to fabricate layer-by-layer porous structures with the size of 12 × 12 × 2 mm3.The scaffolds were fully characterized through a series of physico-chemical and biological assays. Adding the BGs to PCL led to an improvement in the compressive strength of the fabricated scaffolds and increased their hydrophilicity. Furthermore, the PCL/BG scaffolds showed apatite-forming ability (i.e., bioactivity behavior) after being immersed in simulated body fluid (SBF). The in vitro cellular examinations revealed the cytocompatibility of the scaffolds and confirmed them as suitable substrates for the adhesion and proliferation of MG-63 osteosarcoma cells. In conclusion, 3D printed composite scaffolds made of PCL and Sr- and Co-doped BGs might be potentially-beneficial bone replacements, and the achieved results motivate further research on these materials.



Materials ◽  
2021 ◽  
Vol 14 (6) ◽  
pp. 1550
Author(s):  
Soo-Yeon Yoo ◽  
Seong-Kyun Kim ◽  
Seong-Joo Heo ◽  
Jai-Young Koak ◽  
Joung-Gyu Kim

Previous studies on accuracy of three-dimensional (3D) printed model focused on full arch measurements at few points. The aim of this study was to examine the dimensional accuracy of 3D-printed models which were teeth-prepped for three-unit fixed prostheses, especially at margin and proximal contact areas. The prepped dental model was scanned with a desktop scanner. Using this reference file, test models were fabricated by digital light processing (DLP), Multi-Jet printing (MJP), and stereo-lithography apparatus (SLA) techniques. We calculated the accuracy (trueness and precision) of 3D-printed models on 3D planes, and deviations of each measured points at buccolingual and mesiodistal planes. We also analyzed the surface roughness of resin printed models. For overall 3D analysis, MJP showed significantly higher accuracy (trueness) than DLP and SLA techniques; however, there was not any statistically significant difference on precision. For deviations on margins of molar tooth and distance to proximal contact, MJP showed significantly accurate results; however, for a premolar tooth, there was no significant difference between the groups. 3D color maps of printed models showed contraction buccolingually, and surface roughness of the models fabricated by MJP technique was observed as the lowest. The accuracy of the 3D-printed resin models by DLP, MJP, and SLA techniques showed a clinically acceptable range to use as a working model for manufacturing dental prostheses



Pharmaceutics ◽  
2021 ◽  
Vol 13 (9) ◽  
pp. 1524
Author(s):  
Sadikalmahdi Abdella ◽  
Souha H. Youssef ◽  
Franklin Afinjuomo ◽  
Yunmei Song ◽  
Paris Fouladian ◽  
...  

Three-dimensional (3D) printing is among the rapidly evolving technologies with applications in many sectors. The pharmaceutical industry is no exception, and the approval of the first 3D-printed tablet (Spiratam®) marked a revolution in the field. Several studies reported the fabrication of different dosage forms using a range of 3D printing techniques. Thermosensitive drugs compose a considerable segment of available medications in the market requiring strict temperature control during processing to ensure their efficacy and safety. Heating involved in some of the 3D printing technologies raises concerns regarding the feasibility of the techniques for printing thermolabile drugs. Studies reported that semi-solid extrusion (SSE) is the commonly used printing technique to fabricate thermosensitive drugs. Digital light processing (DLP), binder jetting (BJ), and stereolithography (SLA) can also be used for the fabrication of thermosensitive drugs as they do not involve heating elements. Nonetheless, degradation of some drugs by light source used in the techniques was reported. Interestingly, fused deposition modelling (FDM) coupled with filling techniques offered protection against thermal degradation. Concepts such as selection of low melting point polymers, adjustment of printing parameters, and coupling of more than one printing technique were exploited in printing thermosensitive drugs. This systematic review presents challenges, 3DP procedures, and future directions of 3D printing of thermo-sensitive formulations.



2021 ◽  
Vol 22 (21) ◽  
pp. 11600
Author(s):  
Dong Jin Choi ◽  
Kyoung Choi ◽  
Sang Jun Park ◽  
Young-Jin Kim ◽  
Seok Chung ◽  
...  

Gelatin has excellent biological properties, but its poor physical properties are a major obstacle to its use as a biomaterial ink. These disadvantages not only worsen the printability of gelatin biomaterial ink, but also reduce the dimensional stability of its 3D scaffolds and limit its application in the tissue engineering field. Herein, biodegradable suture fibers were added into a gelatin biomaterial ink to improve the printability, mechanical strength, and dimensional stability of the 3D printed scaffolds. The suture fiber reinforced gelatin 3D scaffolds were fabricated using the thermo-responsive properties of gelatin under optimized 3D printing conditions (−10 °C cryogenic plate, 40–80 kPa pneumatic pressure, and 9 mm/s printing speed), and were crosslinked using EDC/NHS to maintain their 3D structures. Scanning electron microscopy images revealed that the morphologies of the 3D printed scaffolds maintained their 3D structure after crosslinking. The addition of 0.5% (w/v) of suture fibers increased the printing accuracy of the 3D printed scaffolds to 97%. The suture fibers also increased the mechanical strength of the 3D printed scaffolds by up to 6-fold, and the degradation rate could be controlled by the suture fiber content. In in vitro cell studies, DNA assay results showed that human dermal fibroblasts’ proliferation rate of a 3D printed scaffold containing 0.5% suture fiber was 10% higher than that of a 3D printed scaffold without suture fibers after 14 days of culture. Interestingly, the supplement of suture fibers into gelatin biomaterial ink was able to minimize the cell-mediated contraction of the cell cultured 3D scaffolds over the cell culture period. These results show that advanced biomaterial inks can be developed by supplementing biodegradable fibers to improve the poor physical properties of natural polymer-based biomaterial inks.



Materials ◽  
2020 ◽  
Vol 13 (18) ◽  
pp. 4066
Author(s):  
Marta Czajkowska ◽  
Ewa Walejewska ◽  
Łukasz Zadrożny ◽  
Monika Wieczorek ◽  
Wojciech Święszkowski ◽  
...  

This study was conducted to test possibilities of application of 3D printed dental models (DMs) in terms of their accuracy and physical properties. In this work, stone models of mandibles were cast from alginate impressions of 10 patients and scanned in order to obtain 3D printed acrylic replicas. The diagnostic value was tested as matching of model scans on three levels: peak of cusps, occlusal surface, and all teeth surfaces. The mechanical properties of acrylic and stone samples, specifically the impact strength, shore D hardness, and flexural and compressive strength were investigated according to ISO standards. The matching of models’ surfaces was the highest on the level of peaks of cusps (average lack of deviations, 0.21 mm) and the lowest on the level of all teeth surfaces (average lack of deviations, 0.64 mm). Acrylic samples subjected to mechanical testing, as expected, showed higher mechanical properties as compared to the specimens made of dental stone. In the present study we demonstrated that 3D printed acrylic models could be ideal representatives in the case of use as a diagnostic tool and as a part of medical records. The acrylic samples exhibited not only higher mechanical properties, but also showed better accuracy comparing to dental stone.



Materials ◽  
2020 ◽  
Vol 13 (23) ◽  
pp. 5433
Author(s):  
Seung-Ho Shin ◽  
Jung-Hwa Lim ◽  
You-Jung Kang ◽  
Jee-Hwan Kim ◽  
June-Sung Shim ◽  
...  

The amount of photopolymer material consumed during the three-dimensional (3D) printing of a dental model varies with the volume and internal structure of the modeling data. This study analyzed how the internal structure and the presence of a cross-arch plate influence the accuracy of a 3D printed dental model. The model was designed with a U-shaped arch and the palate removed (Group U) or a cross-arch plate attached to the palate area (Group P), and the internal structure was divided into five types. The trueness and precision were analyzed for accuracy comparisons of the 3D printed models. Two-way ANOVA of the trueness revealed that the accuracy was 135.2 ± 26.3 µm (mean ± SD) in Group U and 85.6 ± 13.1 µm in Group P. Regarding the internal structure, the accuracy was 143.1 ± 46.8 µm in the 1.5 mm-thick shell group, which improved to 111.1 ± 31.9 µm and 106.7 ± 26.3 µm in the roughly filled and fully filled models, respectively. The precision was 70.3 ± 19.1 µm in Group U and 65.0 ± 8.8 µm in Group P. The results of this study suggest that a cross-arch plate is necessary for the accurate production of a model using 3D printing regardless of its internal structure. In Group U, the error during the printing process was higher for the hollowed models.



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