scholarly journals Medication-Related Osteonecrosis of the Jaw—A Continuing Issue

2021 ◽  
Vol 11 (17) ◽  
pp. 7781
Author(s):  
Krzysztof Wróbel ◽  
Maciej Sikora ◽  
Maciej Chęciński ◽  
Maria Jas ◽  
Dariusz Chlubek
Keyword(s):  
Monoclonal Antibodies ◽  
Oral Cavity ◽  
Angiogenesis Inhibitors ◽  
Osteonecrosis Of The Jaw ◽  
Everyday Practice ◽  
Dental Prostheses ◽  
The Everyday ◽  
The Individual

Introduction: Medication-related osteonecrosis of the jaw (MRONJ) is a condition that is becoming more common in the everyday practice of both dental and maxillofacial surgeons. Materials and methods: This paper aims to provide a comprehensive and easy to read by clinicians presentation of comprehensive, accessible, and up-to-date data on MRONJ. The individual chapters focus on the etiology, epidemiology, diagnosis, prevention, treatment, and recurrence of MRONJ. Results and discussion: It has been observed over the years that among drugs that increase the risk of the disease, apart from bisphosphonates, angiogenesis inhibitors and anti-RANKL monoclonal antibodies should also be included. A thorough physical and subjective examination, periodic correction of dental prostheses, and an adequate preparation for even the simplest of procedures in the oral cavity area can prevent or minimize the risk of MRONJ. Conclusions: It is extremely difficult to treat once it occurs and oftentimes is a recurring problem that leads to a multitude of symptoms that gradually decrease the quality of a patient’s life.

scholarly journals Review of Myeloma Therapies and Their Potential for Oral and Maxillofacial Side Effects

Cancers ◽  
2021 ◽  
Vol 13 (17) ◽  
pp. 4479
Author(s):  
Sophie Beaumont ◽  
Simon Harrison ◽  
Jeremy Er
Keyword(s):  
Quality Of Life ◽  
Side Effects ◽  
Oral Cavity ◽  
Haematological Malignancy ◽  
Bone Fractures ◽  
Osteonecrosis Of The Jaw ◽  
Antiresorptive Therapy ◽  
Maxillofacial Region ◽  
Skeletal Related Events

Myeloma is a common haematological malignancy in which adverse skeletal related events are frequently seen. Over recent years, treatment for myeloma has evolved leading to improved survival. Antiresorptive therapy is an important adjunct therapy to reduce the risk of bone fractures and to improve the quality of life for myeloma patients; however, this has the potential for unwanted side effects in the oral cavity and maxillofacial region. Osteonecrosis of the jaw related to antiresorptive medications and other myeloma therapies is not uncommon. This review serves to highlight the risk of osteonecrosis of the jaw for myeloma patients, with some suggestions for prevention and management.

scholarly journals Entrepreneurship as Everyday Practice: Towards a Personalized Pedagogy of Enterprise Education

2012 ◽  
Vol 26 (6) ◽  
pp. 417-430 ◽  
Author(s):  
Per Blenker ◽  
Signe Hedeboe Frederiksen ◽  
Steffen Korsgaard ◽  
Sabine Müller ◽  
Helle Neergaard ◽  
...  
Keyword(s):  
Conceptual Framework ◽  
Regional Differences ◽  
Entrepreneurship Education ◽  
Personal Life ◽  
Everyday Practice ◽  
Education Curriculum ◽  
Enterprise Education ◽  
The Everyday ◽  
And Gender ◽  
The Individual

Adopting the perspective of ‘entrepreneurship as an everyday practice’ in education, the authors conceptualize opportunities as arising from the everyday practice of individuals. Opportunities are thus seen as emanating from the individual entrepreneur's ability to disclose anomalies and disharmonies in their personal life. The paper illustrates how opportunities unfold depending on regional differences, local heritage and gender, to show how entrepreneurship education must take into account differences in context, culture and circumstance. Rather than perceiving entrepreneurship education as universalistic and searching for a generally applicable teaching approach, the authors argue that there is a need to tailor entrepreneurship education to the particular. They therefore propose that the pedagogy of entrepreneurship education should be personalized and they build a conceptual framework that contrasts two opposing views of entrepreneurship education: ‘universalistic’ and ‘idiosyncratic’. Following this distinction, they explore how different elements of entrepreneurship education may be fitted to the particular needs of each individual learner. This insight is relevant for didactic reflections on single entrepreneurship courses and for the construction of an entrepreneurship education curriculum.

scholarly journals Free time for seniors as an activating action

2017 ◽  
Vol 5 (1) ◽  
pp. 143
Author(s):  
Dorota Rynkowska ◽  
Jarosław Kinal
Keyword(s):  
Leisure Time ◽  
Human Life ◽  
Free Time ◽  
The Everyday ◽  
The World ◽  
Fast Pace ◽  
Demographic Processes ◽  
The Individual ◽  
Intense Activity

Modern civilization is primarily a fast pace of life, a number of changes in human life, the need to face many tasks and Obligations. Free time in contemporary European democratic societies is one of More important non-economic indicators describing the quality of life of citizens (Flora, Noll 1999). Intense activity leads to fatigue, fatigue and sometimes discouragement This to effectively and perform their duties properly and meet the everyday demands, the end is planning zne leisure, entertainment, or leisure time. The sphere of free time fulfills important roles in human life, translated into the quality of the individual and of age Society.This applies to all ages, especially seniors who ruined s are a special category, both adrestatów and Recipients of free time. The demographic processes that we can currently observe in Europe, a Also in many countries around the world, they lead to an increase in number and the proportion of older people in społeczeńst knows. Seniors represent a diverse social group in terms of cultural features, social status, health problems, economic Social. Aging in roses NYM rate, thus roses AD are their needs and forms of activity and lifestyles, Tore correlate with k Date of free timeThe aim of this article is an attempt to present the seniors free time, its functions, types and forms in the context of the activities undertaken by them aktywnoś you.

scholarly journals MUSLIMAH KELAS MENENGAH BERBAGI SUAMI (Studi Kasus Keluarga Poligami di Daerah Istimewa Yogyakarta)

2020 ◽  
Vol 12 (2) ◽  
pp. 184
Author(s):  
Malpha Della Thalita
Keyword(s):  
Middle Class ◽  
Everyday Practice ◽  
Polygamous Marriage ◽  
The Everyday ◽  
Phenomenological Perspective ◽  
The Individual

This article discuses about the everyday practice of poligamy among Middle Class Muslims in Yogyakarta from the perspective of the wives. Utilizing the benefits of phenomenological perspective concentrating on the individual experiences, this paper argued that the willingness to live in polygamous marriage comes from the husbands, the wives, or both the husbands and the wives. In everyday live, the wives argued that they could fullfil the rights and the obligations as they got the the religious and economic guarantees from their husbands.[Studi ini mengkaji keluarga poligami yang terjadi di kalangan kelas menengah Muslim di Yogyakarta dengan fokus bahasan pada proses kehidupan keluarga poligami, alasan hidup dalam keluarga poligami dan pemenuhan hak dan kewajiban mereka dari perspektif isteri-isteri keluarga poligami. Dengan penggunakan pendekatan fenomenologi yang menitikberatkan pada perasaan dan pengalaman individu, tulisan ini menyatakan bahwa inisiatif berpoligami dapat berasal dari suami, isteri, atau dari keduanya. Sedangkan alasan kesediaan informan dipoligami adalah untuk alasan biologis untuk meneruskan keturunan, dan alasan agama dan ekonomi. Dalam kehidupan sehari-hari, para responden menyatakan bahwa hak dan kewajiban dalam keluarga poligami mereka telah terpenuhi dengan baik, baik nafkah lahir maupun nafkah batin. Mereka menyatakan bahwa mereka mendapat jaminan fungsi religious, serta ada jaminan fungsi ekonomi.]

Semi-automated methods for 3-D reconstruction of macromolecular complexes

1995 ◽  
Vol 53 ◽  
pp. 42-43
Author(s):  
B. Carragher ◽  
M. Whittaker
Keyword(s):  
Three Dimensional ◽  
Time Saving ◽  
Macromolecular Complexes ◽  
Symmetry Properties ◽  
Dimensional Reconstruction ◽  
Experienced Operator ◽  
Projection Images ◽  
The Individual ◽  
Natural Symmetry

Techniques for three-dimensional reconstruction of macromolecular complexes from electron micrographs have been successfully used for many years. These include methods which take advantage of the natural symmetry properties of the structure (for example helical or icosahedral) as well as those that use single axis or other tilting geometries to reconstruct from a set of projection images. These techniques have traditionally relied on a very experienced operator to manually perform the often numerous and time consuming steps required to obtain the final reconstruction. While the guidance and oversight of an experienced and critical operator will always be an essential component of these techniques, recent advances in computer technology, microprocessor controlled microscopes and the availability of high quality CCD cameras have provided the means to automate many of the individual steps.During the acquisition of data automation provides benefits not only in terms of convenience and time saving but also in circumstances where manual procedures limit the quality of the final reconstruction.

Manageable Self in the Early Hellenistic Era

2010 ◽  
Vol 39 (2) ◽  
pp. 34-36
Author(s):  
Vaia Touna
Keyword(s):  
Social Economic ◽  
Ancient Greece ◽  
The Self ◽  
Hellenistic Period ◽  
Political Conditions ◽  
The Individual

This paper argues that the rise of what is commonly termed "personal religion" during the Classic-Hellenistic period is not the result of an inner need or even quality of the self, as often argued by those who see in ancient Greece foreshadowing of Christianity, but rather was the result of social, economic, and political conditions that made it possible for Hellenistic Greeks to redefine the perception of the individual and its relationship to others.

Reflecting the Sky in Water

2017 ◽  
Vol 3 (1) ◽  
pp. 112-126 ◽  
Author(s):  
Ilaria Cristofaro
Keyword(s):  
The Unconscious ◽  
Related Case ◽  
Quality Of Water ◽  
Fluid Properties ◽  
Phenomenological Perspective ◽  
Auto Ethnography ◽  
The Individual ◽  
Artificial Water ◽  
Land Water

From a phenomenological perspective, the reflective quality of water has a visually dramatic impact, especially when combined with the light of celestial phenomena. However, the possible presence of water as a means for reflecting the sky is often undervalued when interpreting archaeoastronomical sites. From artificial water spaces, such as ditches, huacas and wells to natural ones such as rivers, lakes and puddles, water spaces add a layer of interacting reflections to landscapes. In the cosmological understanding of skyscapes and waterscapes, a cross-cultural metaphorical association between water spaces and the underworld is often revealed. In this research, water-skyscapes are explored through the practice of auto-ethnography and reflexive phenomenology. The mirroring of the sky in water opens up themes such as the continuity, delimitation and manipulation of sky phenomena on land: water spaces act as a continuation of the sky on earth; depending on water spaces’ spatial extension, selected celestial phenomena can be periodically reflected within architectures, so as to make the heavenly dimension easily accessible and a possible object of manipulation. Water-skyscapes appear as specular worlds, where water spaces are assumed to be doorways to the inner reality of the unconscious. The fluid properties of water have the visual effect of dissipating borders, of merging shapes, and, therefore, of dissolving identities; in the inner landscape, this process may represent symbolic death experiences and rituals of initiation, where the annihilation of the individual allows the creative process of a new life cycle. These contextually generalisable results aim to inspire new perspectives on sky-and-water related case studies and give value to the practice of reflexive phenomenology as crucial method of research.

QUALITY OF INDIVIDUAL AND GROUP LEVEL INTERVENTIONS FOR FIRST EPISODE PSYCHOSIS AT THE TERTIARY PSYCHIATRIC HOSPITAL IN UGANDA.

2020 ◽  
Author(s):  
Emmanuel Kiiza Mwesiga ◽  
Noeline Nakasujja ◽  
Lawrence Nankaba ◽  
Juliet Nakku ◽  
Seggane Musisi
Keyword(s):  
Psychiatric Hospital ◽  
Psychotic Disorders ◽  
First Episode Psychosis ◽  
First Episode ◽  
Group Level ◽  
Group Interventions ◽  
Episode Psychosis ◽  
Essential Components ◽  
The Individual

Introduction: Individual and group level interventions have the largest effect on outcomes in patients with the first episode of psychosis. The quality of these individual and group level interventions provided to first-episode psychosis patients in Uganda is unclear.Methods: The study was performed at Butabika National Psychiatric Teaching and referral hospital in Uganda. A retrospective chart review of recently discharged adult in-patients with the first episode of psychosis was first performed to determine the proportion of participants who received the different essential components for individual and group level interventions. From the different proportions, the quality of the services across the individual and group interventions was determined using the first-Episode Psychosis Services Fidelity Scale (FEPS-FS). The FEPS-FS assigns a grade of 1-5 on a Likert scale depending on the proportion of patients received the different components of the intervention. Results: The final sample included 156 first-episode psychosis patients. The median age was 27 years [IOR (24-36)] with 55% of participants of the female gender. 13 essential components across the individual and group interventions were assessed and their quality quantified. All 13 essential components had poor quality with the range of scores on the FEPS-FS of 1-3. Only one essential component assessed (use of single antipsychotics) had moderate quality.Discussion: Among current services at the National psychiatric hospital of Uganda, the essential for individual and group level interventions for psychotic disorders are of low quality. Further studies are required on how the quality of these interventions can be improved.

THE VALUE OF LOVE IN THE SYSTEM OF FORMATION OF THE PROFESSIONAL MATURITY OF THE EDUCATOR

2020 ◽  
Vol 1 (10(79)) ◽  
pp. 12-18
Author(s):  
G. Bubyreva
Keyword(s):  
Russian Federation ◽  
The State ◽  
Educational Process ◽  
Wide Range ◽  
The Family ◽  
The Russian Federation ◽  
The Government ◽  
The Individual ◽  
The Right

The existing legislation determines the education as "an integral and focused process of teaching and upbringing, which represents a socially important value and shall be implemented so as to meet the interests of the individual, the family, the society and the state". However, even in this part, the meaning of the notion ‘socially significant benefit is not specified and allows for a wide range of interpretation [2]. Yet the more inconcrete is the answer to the question – "who and how should determine the interests of the individual, the family and even the state?" The national doctrine of education in the Russian Federation, which determined the goals of teaching and upbringing, the ways to attain them by means of the state policy regulating the field of education, the target achievements of the development of the educational system for the period up to 2025, approved by the Decree of the Government of the Russian Federation of October 4, 2000 #751, was abrogated by the Decree of the Government of the Russian Federation of March 29, 2014 #245 [7]. The new doctrine has not been developed so far. The RAE Academician A.B. Khutorsky believes that the absence of the national doctrine of education presents a threat to national security and a violation of the right of citizens to quality education. Accordingly, the teacher has to solve the problem of achieving the harmony of interests of the individual, the family, the society and the government on their own, which, however, judging by the officially published results, is the task that exceeds the abilities of the participants of the educational process.  The particular concern about the results of the patriotic upbringing served as a basis for the legislative initiative of the RF President V. V. Putin, who introduced the project of an amendment to the Law of RF "About Education of the Russian Federation" to the State Duma in 2020, regarding the quality of patriotic upbringing [3]. Patriotism, considered by the President of RF V. V. Putin as the only possible idea to unite the nation is "THE FEELING OF LOVE OF THE MOTHERLAND" and the readiness for every sacrifice and heroic deed for the sake of the interests of your Motherland. However, the practicing educators experience shortfalls in efficient methodologies of patriotic upbringing, which should let them bring up citizens, loving their Motherland more than themselves. The article is dedicated to solution to this problem based on the Value-sense paradigm of upbringing educational dynasty of the Kurbatovs [15].

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