scholarly journals Metallic Nanoparticles Obtained via “Green” Synthesis as a Platform for Biosensor Construction

2019 ◽  
Vol 9 (4) ◽  
pp. 720 ◽  
Author(s):  
Galina Gayda ◽  
Olha Demkiv ◽  
Nataliya Stasyuk ◽  
Roman Serkiz ◽  
Maksym Lootsik ◽  
...  
Keyword(s):  
Green Synthesis ◽  
Metallic Nanoparticles ◽  
Alcohol Oxidase ◽  
Inorganic Ions ◽  
Special Role ◽  
Graphite Electrodes ◽  
Fluorescent Markers ◽  
Extracellular Metabolites ◽  
Very High

Novel nanomaterials, including metallic nanoparticles obtained via green synthesis (gNPs), have a great potential for application in biotechnology, industry and medicine. The special role of gNPs is related to antibacterial agents, fluorescent markers and carriers for drug delivery. However, application of gNPs for construction of amperometric biosensors (ABSs) is not well documented. The aim of the current research was to study potential advantages of using gNPs in biosensorics. The extracellular metabolites of the yeast Ogataea polymorpha were used as reducing agents for obtaining gNPs from the corresponding inorganic ions. Several gNPs were synthesized, characterized and tested as enzyme carriers on the surface of graphite electrodes (GEs). The most effective were Pd-based gNPs (gPdNPs), and these were studied further and applied for construction of laccase- and alcohol oxidase (AO)-based ABSs. AO/GE, AO-gPdNPs/GE, laccase/GE and laccase-gPdNPs/GE were obtained, and their analytical characteristics were studied. Both gPdNPs-modified ABSs were found to have broader linear ranges and higher storage stabilities than control electrodes, although they are less sensitive toward corresponding substrates. We thus conclude that gPdNPs may be promising for construction of ABSs for enzymes with very high affinities to their substrates.

scholarly journals “Green” Synthesis of Metallic Nanoparticles by Sonoelectrochemical and Sonogalvanic Replacement Methods

2021 ◽  
Vol 2021 ◽  
pp. 1-17
Author(s):  
Оrest Kuntyi ◽  
Galyna Zozulya ◽  
Andriy Kytsya
Keyword(s):  
Green Synthesis ◽  
Electrochemical Reduction ◽  
Metallic Nanoparticles ◽  
Bimetallic Nanoparticles ◽  
Galvanic Replacement ◽  
Pulsed Ultrasound ◽  
Environmental Friendliness ◽  
And Shock Waves ◽  
Sonoelectrochemical Synthesis

The main features of the “green” synthesis of metallic nanoparticles (MNPs) by the sonoelectrochemical methods are manufacturability, environmental friendliness, and the possibility of controlling the geometry of the forming particles. The electrochemical reduction technique allows efficiently designing the metal nanoparticles and provides the control of the content of components of bimetallic nanoparticles, as well as minimizing the number of precursors in working solutions. Due to the generation of turbulence, microjets, and shock waves, ultrasound increases mass transfer and formation of radicals in aqueous solutions and, accordingly, accelerates the processes of nucleation and growth of MNPs. Therefore, this hybrid method, which combines electrolysis and ultrasound, has attracted the interest of researchers in the last two decades as one of the most promising techniques. The present work presents a short analysis of the reference literature on sonoelectrochemical synthesis of metallic and bimetallic nanoparticles. The main factors influencing the geometry of nanoparticles and their size distribution are analyzed. The use of pulsed ultrasound and pulsed current supply during sonoelectrochemical synthesis is especially effective in designing MNPs. Emphasis is placed on the role of surfactants in the formation of MNPs and sacrificial anodes in providing the algorithm: “anodic dissolution-electrochemical reduction of metal-nucleation and formation of МNPs.” It is noted that ultrasound allows synthesizing the MNPs and M1M2NPs during the galvanic replacement, and an analogy of the formation of nanoparticles by sonogalvanic replacement and sonoelectrochemical method is shown.

scholarly journals Gastrointestinal Disorders in Peritoneal Dialysis Patients

2018 ◽  
Vol 48 (5) ◽  
pp. 319-325 ◽  
Author(s):  
George Kosmadakis ◽  
Julie Albaret ◽  
Enrique da Costa Correia ◽  
Frederic Somda ◽  
Didier Aguilera
Keyword(s):  
Peritoneal Dialysis ◽  
Gastroesophageal Reflux ◽  
Abdominal Hernia ◽  
Diagnostic Tools ◽  
Special Role ◽  
Peptic Ulcers ◽  
Instrumental Methods ◽  
Very High

Background: Gastrointestinal (GI) disorders in peritoneal dialysis (PD) patients are relatively understudied in the literature, even though they have a serious impact in the morbidity parameters and the quality of life for this group of patients. Various diagnostic tools have been used, including instrumental methods and questionnaires, invariably validated in comparative studies. Summary: The prevalence of GI disorders is very high in PD patients. Compared to the haemodialysis patients they present a higher prevalence of reflux, eating dysfunction, gastroesophageal reflux, intestinal obstruction or adhesions and abdominal hernia. They may be divided into Gastric disorders (Gastroesophageal reflux disease, pathological Gastric emptying, Dyspepsia, Helicobacter pylori infection, peptic ulcers) and Intestinal disorders (Peritonitis, Diverticulosis, Constipation). Key Messages: The current paper is a review of the literature involving GI disorders in PD patients. This special group of patients with a special role of the peritoneal cavity and the GI motility in the physiology of their dialysis merit a larger number of studies dealing with the interrelation of the GI tract and the PD physiological, functional and pathophysiological parameters.

Development of Social and Economic Forecasting and Ideas of A. Anchishkin

2013 ◽  
pp. 143-155
Author(s):  
A. Klepach ◽  
G. Kuranov
Keyword(s):  
Economic Planning ◽  
Special Role ◽  
Economic Management ◽  
Economic Forecasting ◽  
Russian Economy ◽  
World Economic ◽  
Long Term Forecasting ◽  
Working Out

The role of the prominent Soviet economist, academician A. Anchishkin (1933—1987), whose 80th birth anniversary we celebrate this year, in the development of ideas and formation of economic forecasting in the country at the time when the directive planning acted as a leading tool of economic management is explored in the article. Besides, Anchishkin’s special role is noted in developing a comprehensive program of scientific and technical progress, an information basis for working out long-term forecasts of the country’s development, moreover, his contribution to the creation of long-term forecasting methodology and improvement of the statistical basis for economic analysis and economic planning. The authors show that social and economic forecasting in the period after 1991, which has undertaken a number of functions of economic planning, has largely relied on further development of Anchishkin’s ideas, at the same time responding to new challenges for the Russian economy development during its entry into the world economic system.

THE ROLE OF GRASSLAND IN MANAGEMENT

1968 ◽  
pp. 44-49
Author(s):  
B.K. Cameron
Keyword(s):  
Soil Temperature ◽  
Annual Rainfall ◽  
Silt Loam ◽  
Average Annual Rainfall ◽  
Very High ◽  
Wilting Point

THE PROPERTY to be discussed is a mixed sheep and cropping unit, situated ei ht a miles east of Ashburton and midway between the Ra aia and the Ashburton rivers. Average annual rainfall is 27 in., evenly spread, but there is very high summer evaporation and therefore frequent droughts. On average, the soil is below wilting point for 40 to 50 days each summer. Winters are cold with the soil temperature being below 48°F for about four months each year. The soil is a Lismore stony silt loam averaging 9 in. in depth over gravel.

Role of Vasavaleha in the management of Covid19

2020 ◽  
Vol 11 (SPL1) ◽  
pp. 259-261
Author(s):  
Aamir Khan ◽  
Rajni K. Gurmule
Keyword(s):  
Immune System ◽  
Human Body ◽  
Respiratory Diseases ◽  
Spreading Rate ◽  
Host Immune System ◽  
Shortness Of Breath ◽  
Antitussive Effect ◽  
Corona Viruses ◽  
Very High

Vasavaleha is one of the best medicine given for respiratory diseases. Corona viruses typically affect the respiratory system, causing symptoms such as coughing, fever and shortness of breath. It also affects host immune system of human body. Spreading rate of this disease is very high. Whole world is seeking for the treatment which can uproots this diseases. There in no vaccine available till date against this pandemic disease. Ayurveda mainly focuses on prevention of diseases alongwith its total cure. Rajyakshma Vyadhi is MadhyamMarga Roga as per Ayurveda. It shows many symptoms such as Kasa, Shwasa etc. By overall view of Covid 19, shows its resemblance with Rajyakshma Vyadhi described in Ayurveda. Vasavaleha is a Kalpa which is described in Rogadhikara of Rajyakshma. It shows Kasahara, Shwashara properties. It consists of Vasa, Pipalli, Madhu and Goghrita. These components shows actions like bronchodilation, antitussive effect and many more other actions. Pipalli shows important Rasayana effect. So in present review, we have tried to focus on role of Vasavaleha in the management of Covid 19. This can be used as preventive as well as adjuvant medication in treating Covid 19. There is need of further clinical research to rule of exact action of Vasavaleha against Covid 19.

METHODOLOGY OF PLAYING ACTIVITY IN REHABILITATION PRACTICE

2018 ◽  
Vol 28 (7) ◽  
pp. 2543-2548
Author(s):  
Petya Kasnakova
Keyword(s):  
Positive Emotions ◽  
Healing Process ◽  
Disease Process ◽  
Special Role ◽  
Thought Processes ◽  
Active Involvement ◽  
Movement Skills ◽  
Movement Training ◽  
Motor Movement

The games play a special role in rehabilitation practice. The positive emotions they cause in patients cannot be achieved by other methods and means of modern rehabilitation. The role of game playing activity in practice is crucial to the achievement of one of the important tasks in implementing rehabilitation measures, namely to evacuate the patient from the depressed mental state, to distract him from the disease process and to focus on mobilizing his healing powers. The mood, the emotional charge and the dynamics that the games create are particularly suited to awakening the patient's interest in the healing process, their attraction and their active involvement in the rehabilitation activities. The connection between the actions in the game and the movements in the analytical exercises accelerates the formation of motor habits, physical qualities and skills not only in children but also in adult patients with various pathological injuries. Rehabilitation games are suitable for all ages by enhancing the health of the occupants, developing their mental qualities, improving the activity of the vestibular, visual and motor analyzers. The basis of the motor movement training game methodology and the improvement of motor movement skills is the activation of the thought processes and emotional experiences, the development of the functions of the musculoskeletal system, the cardiovascular system and the respiratory system.

РОЛЬ КНИГИ В ВОСПИТАНИИ ПОЛИКУЛЬТУРНОЙ ЛИЧНОСТИ

2020 ◽  
pp. 58-60
Author(s):  
Замира Сейткожоева
Keyword(s):  
Computer Games ◽  
Human Life ◽  
Interpersonal Relationship ◽  
Special Role ◽  
Multicultural Personality ◽  
Younger Age ◽  
Bibliographic Data ◽  
Life Education ◽  
Different Cultures

Аннотация: В статье обращено внимание на исключительную роль книги в жизни человека, воспитание молодежи. Книга сопровождает человека всю жизнь. Однако в последние годы замечается снижение интереса к чтению книг. Отдается предпочтение компьютеру, играм, телевизору, слушанию музыки через наушники. Во избежание деградации личности, в воспитании грамотной, гуманной, толерантной личности необходимо приучать подрастающее поколение к вдумчивому чтению книг. Значительное место в развитии личности занимает внеклассное чтение, к которому нужно прививать интерес еще во время учебы в младшем возрасте. В мире особая роль принадлежит межличностным отношениям, формированию такой личности, которая могла бы жить в согласии с носителями разных культур. Для формирования поликультурной личности важная роль принадлежит культурному наследию, основу которого составляют книги. Ключевые слова: роль книги, гуманная личность, толерантная личность, библиографические материалы, указатели библиографических данных, справочная литература, поликультурная личность, внеклассное чтение, информатизация, интерес к чтению. Аннотация: Макалада адамдын жашоосундагы жаштарды тарбиялоодогу китептин өзгөчө мааниси, ролуна өзгөчө көңүл бурулган. Бир эле мезгилде, соңку жылдарда китептерибизге болгон адамдардын кызыгууларды төмөндөп бараткандыгы байкалган.Учурда поли- же ар кандай оюндарга, телевизор көрүүгө, кулакчын аркылуу модалуу музыка угууга, артыкчылык берилип жатат. Билимдүү, гумандуу толеранттуу инсанды тарбиялап чыгууга да, анын деградацияга кабылышынан сактап калыш үчүн, өсүп келе жаткан муундарды өзүнүн айкалыштыра алуусу менен китептерди берилип жана ой жүгүртүп алууга үйрөтүү- өтө зарыл талап болуп эсептелет. Инсандын онүгүндө окуудан тышкаркы окуунун маанилүү орду бар. Мындай окууга буга кызыгуусун өркүндөтүүнун башталгыч каласстардан тарта үйрөтүү абзел. Инсандар аралык байланыштар дүйнөдө өзгөчө орун ээлейт, алар башка маданий өкүлдөрү менен макулдуктулукта жашоого даяр. Полимаданиятту инсандын калыптанышына ар маданияттын мурасы өтө чоң ролду ойнойт, анын негизин китептер түзөт. Түйүндүү сөздөр: китептин мааниси жана ролу, гумандуу инсан, толеранттуу инсан, библиографиялык материалдар, библиографиялык маалыматтарды көрсөтүү сурантыла билүү адабияты, полимаданиятуу инсан, окуудан тышкаркы окуу,маалымдуулук, окууга кызыгуу The article draws attention to the exceptional role of the book in human life, education of young people. The book accompanies a person all his life. However, in recent years, there has been a decline in interest in reading books. Preference is given to a computer, games, TV, listening to music through headphones. In order to avoid degradation of the personality, it is necessary to accustom the younger generation to thoughtful reading of books. a significant place in the development of personality takes extracurricular reading, to which you need to instill interest even while studying at a younger age. In the world a special role belongs to interpersonal relationship, the formation of such a personality, who could live in harmony with speakers of different cultures. To form a multicultural personality an important role belongs to cultural heritage, the basis of which are books Keywords: the role of the book, humane personality, tolerant personality, bibliographic materials, indexes of bibliographic data, reference literature, multicultural personality, extracurricular reading, informatization, interest in reading.

Metallic Nanoparticle Synthesis by Green Chemistry

2018 ◽  
Vol 11 (6) ◽  
pp. 4287-4294
Author(s):  
Anikate Sood ◽  
Shweta Agarwal
Keyword(s):  
Green Chemistry ◽  
Green Synthesis ◽  
Biomedical Research ◽  
Metallic Nanoparticles ◽  
Nanoparticle Synthesis ◽  
Synthesis Methods ◽  
Metallic Nanoparticle ◽  
Medical Field ◽  
Advantages And Disadvantages ◽  
Gold Silver

Nanotechnology is the most sought field in biomedical research. Metallic nanoparticles have wide applications in the medical field and have gained the attention of various researchers for advanced research for their application in pharmaceutical field. A variety of metallic nanoparticles like gold, silver, platinum, palladium, copper and zinc have been developed so far. There are different methods to synthesize metallic nanoparticles like chemical, physical, and green synthesis methods. Chemical and physical approaches suffer from certain drawbacks whereas green synthesis is emerging as a nontoxic and eco-friendly approach in production of metallic nanoparticles. Green synthesis is further divided into different approaches like synthesis via bacteria, fungi, algae, and plants. These approaches have their own advantages and disadvantages. In this article, we have described various metallic nanoparticles, different modes of green synthesis and brief description about different metabolites present in plant that act as reducing agents in green synthesis of metallic nanoparticles. 

Diet and Nutritional Interventions with the Special Role of Myo-Inositol in Gestational Diabetes Mellitus Management. An Evidence-Based Critical Appraisal

2019 ◽  
Vol 25 (22) ◽  
pp. 2467-2473 ◽  
Author(s):  
Enrique Reyes-Muñoz ◽  
Federica Di Guardo ◽  
Michal Ciebiera ◽  
Ilker Kahramanoglu ◽  
Thozhukat Sathyapalan ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Gestational Diabetes ◽  
Gestational Diabetes Mellitus ◽  
Metabolic Diseases ◽  
Nutritional Intervention ◽  
Attractive Alternative ◽  
Special Role ◽  
Dose Frequency ◽  
Nutritional Interventions

Background: Gestational Diabetes Mellitus (GDM), defined as glucose intolerance with onset or first recognition during pregnancy, represents one of the most common maternal-fetal complications during pregnancy and it is associated with poor perinatal outcomes. To date, GDM is a rising condition over the last decades coinciding with the ongoing epidemic of obesity and Type 2 Diabetes Mellitus (T2DM). Objective: The aim of this review is to discuss the role of diet and nutritional interventions in preventing GDM with the explanation of the special role of myo-inositol (MI) in this matter. Methods: We performed an overview of the most recent literature data on the subject with particular attention to the effectiveness of diet and nutritional interventions in the prevention of GDM with the special role of MI. Results: Nutritional intervention and physical activity before and during pregnancy are mandatory in women affected by GDM. Moreover, the availability of insulin-sensitizers such as different forms of inositol has dramatically changed the scenario, allowing the treatment of several metabolic diseases, such as those related to glucose dysbalance. Although the optimal dose, frequency, and form of MI administration need to be further investigated, diet supplementation with MI appears to be an attractive alternative for the GDM prevention as well as for the reduction of GDM-related complications. Conclusion: More studies should be conducted to prove the most effective nutritional intervention in GDM. Regarding the potential effectiveness of MI, further evidence in multicenter, randomized controlled trials is needed to draw firm conclusions.

The Role of Lipids and Membranes in the Pathogenesis of Alzheimer's Disease: A Comprehensive View

2018 ◽  
Vol 15 (13) ◽  
pp. 1191-1212 ◽  
Author(s):  
Botond Penke ◽  
Gábor Paragi ◽  
János Gera ◽  
Róbert Berkecz ◽  
Zsolt Kovács ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Signaling Pathways ◽  
Membrane Lipids ◽  
Specific Protein ◽  
Dietary Factors ◽  
Lipid Signaling ◽  
Special Role ◽  
Aβ Peptides

Lipids participate in Amyloid Precursor Protein (APP) trafficking and processing - important factors in the initiation of Alzheimer’s disease (AD) pathogenesis and influence the formation of neurotoxic β-amyloid (Aβ) peptides. An important risk factor, the presence of ApoE4 protein in AD brain cells binds the lipids to AD. In addition, lipid signaling pathways have a crucial role in the cellular homeostasis and depend on specific protein-lipid interactions. The current review focuses on pathological alterations of membrane lipids (cholesterol, glycerophospholipids, sphingolipids) and lipid metabolism in AD and provides insight in the current understanding of biological membranes, their lipid structures and functions, as well as their role as potential therapeutic targets. Novel methods for studying the membrane structure and lipid composition will be reviewed in a broad sense whereas the use of lipid biomarkers for early diagnosis of AD will be shortly summarized. Interactions of Aβ peptides with the cell membrane and different subcellular organelles are reviewed. Next, the details of the most important lipid signaling pathways, including the role of the plasma membrane as stress sensor and its therapeutic applications are given. 4-hydroxy-2-nonenal may play a special role in the initiation of the pathogenesis of AD and thus the “calpain-cathepsin hypothesis” of AD is highlighted. Finally, the most important lipid dietary factors and their possible use and efficacy in the prevention of AD are discussed.

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