scholarly journals Special Issue Editorial: Nanoparticles in the Atmosphere

Atmosphere ◽  
2020 ◽  
Vol 11 (1) ◽  
pp. 61
Author(s):  
Jorma Joutsensaari

The aim of this Special Issue was to gain insight into the current knowledge on nanoparticles in the atmosphere, from laboratory and field measurements to theoretical and modelling studies of nanoparticles from various atmospheric environments [...]

2006 ◽  
Vol 73 ◽  
pp. 109-119 ◽  
Author(s):  
Chris Stockdale ◽  
Michael Bruno ◽  
Helder Ferreira ◽  
Elisa Garcia-Wilson ◽  
Nicola Wiechens ◽  
...  

In the 30 years since the discovery of the nucleosome, our picture of it has come into sharp focus. The recent high-resolution structures have provided a wealth of insight into the function of the nucleosome, but they are inherently static. Our current knowledge of how nucleosomes can be reconfigured dynamically is at a much earlier stage. Here, recent advances in the understanding of chromatin structure and dynamics are highlighted. The ways in which different modes of nucleosome reconfiguration are likely to influence each other are discussed, and some of the factors likely to regulate the dynamic properties of nucleosomes are considered.


2021 ◽  
Vol 7 (4) ◽  
pp. 316
Author(s):  
Birgit Willinger

I would like to thank all the authors contributing to this Special Issue [...]


2021 ◽  
Vol 7 (7) ◽  
pp. 539
Author(s):  
Tamás Plaszkó ◽  
Zsolt Szűcs ◽  
Gábor Vasas ◽  
Sándor Gonda

Plants heavily rely on chemical defense systems against a variety of stressors. The glucosinolates in the Brassicaceae and some allies are the core molecules of one of the most researched such pathways. These natural products are enzymatically converted into isothiocyanates (ITCs) and occasionally other defensive volatile organic constituents (VOCs) upon fungal challenge or tissue disruption to protect the host against the stressor. The current review provides a comprehensive insight on the effects of the isothiocyanates on fungi, including, but not limited to mycorrhizal fungi and pathogens of Brassicaceae. In the review, our current knowledge on the following topics are summarized: direct antifungal activity and the proposed mechanisms of antifungal action, QSAR (quantitative structure-activity relationships), synergistic activity of ITCs with other agents, effects of ITCs on soil microbial composition and allelopathic activity. A detailed insight into the possible applications is also provided: the literature of biofumigation studies, inhibition of post-harvest pathogenesis and protection of various products including grains and fruits is also reviewed herein.


2021 ◽  
Vol 6 (1) ◽  
Author(s):  
Zi Wang ◽  
Pan Wang ◽  
Yanan Li ◽  
Hongling Peng ◽  
Yu Zhu ◽  
...  

AbstractHematopoiesis requires finely tuned regulation of gene expression at each stage of development. The regulation of gene transcription involves not only individual transcription factors (TFs) but also transcription complexes (TCs) composed of transcription factor(s) and multisubunit cofactors. In their normal compositions, TCs orchestrate lineage-specific patterns of gene expression and ensure the production of the correct proportions of individual cell lineages during hematopoiesis. The integration of posttranslational and conformational modifications in the chromatin landscape, nucleosomes, histones and interacting components via the cofactor–TF interplay is critical to optimal TF activity. Mutations or translocations of cofactor genes are expected to alter cofactor–TF interactions, which may be causative for the pathogenesis of various hematologic disorders. Blocking TF oncogenic activity in hematologic disorders through targeting cofactors in aberrant complexes has been an exciting therapeutic strategy. In this review, we summarize the current knowledge regarding the models and functions of cofactor–TF interplay in physiological hematopoiesis and highlight their implications in the etiology of hematological malignancies. This review presents a deep insight into the physiological and pathological implications of transcription machinery in the blood system.


2021 ◽  
Vol 12 (1) ◽  
Author(s):  
Evan Miles ◽  
Michael McCarthy ◽  
Amaury Dehecq ◽  
Marin Kneib ◽  
Stefan Fugger ◽  
...  

AbstractGlaciers in High Mountain Asia generate meltwater that supports the water needs of 250 million people, but current knowledge of annual accumulation and ablation is limited to sparse field measurements biased in location and glacier size. Here, we present altitudinally-resolved specific mass balances (surface, internal, and basal combined) for 5527 glaciers in High Mountain Asia for 2000–2016, derived by correcting observed glacier thinning patterns for mass redistribution due to ice flow. We find that 41% of glaciers accumulated mass over less than 20% of their area, and only 60% ± 10% of regional annual ablation was compensated by accumulation. Even without 21st century warming, 21% ± 1% of ice volume will be lost by 2100 due to current climatic-geometric imbalance, representing a reduction in glacier ablation into rivers of 28% ± 1%. The ablation of glaciers in the Himalayas and Tien Shan was mostly unsustainable and ice volume in these regions will reduce by at least 30% by 2100. The most important and vulnerable glacier-fed river basins (Amu Darya, Indus, Syr Darya, Tarim Interior) were supplied with >50% sustainable glacier ablation but will see long-term reductions in ice mass and glacier meltwater supply regardless of the Karakoram Anomaly.


2011 ◽  
Vol 1 (5) ◽  
pp. 1-2
Author(s):  
Lavkush Dwivedi

Infectious diseases and consequent immune imbalancesare major constraint in human health managementthroughout the world. However, in recentdecades enormous efforts have been made to elucidatethe immunomodulatory approaches againstinfectious diseases. Immunomodulation is a therapeuticapproach in which we try to intervene inauto regulating processes of the defense system toadjust the immune response at a desired level.The present special issue on cutting edge issues inImmunomodulation like Immune stimulation, Immunesuppression, Immune potentiating and immunereinforcement summarizes our current understandingof this complex mosaic. The accompanyingselection of recent articles from across theworld provides further insight into this topic. 


2014 ◽  
Vol 11 (4) ◽  
pp. 1199-1213 ◽  
Author(s):  
A. M. Ågren ◽  
I. Buffam ◽  
D. M. Cooper ◽  
T. Tiwari ◽  
C. D. Evans ◽  
...  

Abstract. The controls on stream dissolved organic carbon (DOC) concentrations were investigated in a 68 km2 catchment by applying a landscape-mixing model to test if downstream concentrations could be predicted from contributing landscape elements. The landscape-mixing model reproduced the DOC concentration well throughout the stream network during times of high and intermediate discharge. The landscape-mixing model approach is conceptually simple and easy to apply, requiring relatively few field measurements and minimal parameterisation. Our interpretation is that the higher degree of hydrological connectivity during high flows, combined with shorter stream residence times, increased the predictive power of this whole watershed-based mixing model. The model was also useful for providing a baseline for residual analysis, which highlighted areas for further conceptual model development. The residual analysis indicated areas of the stream network that were not well represented by simple mixing of headwaters, as well as flow conditions during which simple mixing based on headwater watershed characteristics did not apply. Specifically, we found that during periods of baseflow the larger valley streams had much lower DOC concentrations than would be predicted by simple mixing. Longer stream residence times during baseflow and changing hydrological flow paths were suggested as potential reasons for this pattern. This study highlights how a simple landscape-mixing model can be used for predictions as well as providing a baseline for residual analysis, which suggest potential mechanisms to be further explored using more focused field and process-based modelling studies.


2020 ◽  
Author(s):  
Kary Ocaña ◽  
Micaella Coelho ◽  
Guilherme Freire ◽  
Carla Osthoff

Bayesian phylogenetic algorithms are computationally intensive. BEAST 1.10 inferences made use of the BEAGLE 3 high-performance library for efficient likelihood computations. The strategy allows phylogenetic inference and dating in current knowledge for SARS-CoV-2 transmission. Follow-up simulations on hybrid resources of Santos Dumont supercomputer using four phylogenomic data sets, we characterize the scaling performance behavior of BEAST 1.10. Our results provide insight into the species tree and MCMC chain length estimation, identifying preferable requirements to improve the use of high-performance computing resources. Ongoing steps involve analyzes of SARS-CoV-2 using BEAST 1.8 in multi-GPUs.


2015 ◽  
Vol 2 ◽  
pp. e004 ◽  
Author(s):  
Andrea Ganthaler ◽  
S. Mayr

Dwarf shrubs exhibit different requirements for a safe and efficient water supply compared to trees due their basitonic branching and low growth height. Though, only few studies dealt with the hydraulics of this growth form. Here we report key hydraulic parameters (vulnerability to drought-induced embolism, xylem hydraulic conductivity, cell osmotic potential, potential at turgor loss point) and related wood anatomical traits for Vaccinium gaultherioides, a wide-spread species in the European Alps. The results affirm the current knowledge, by indicating a relatively risky hydraulic strategy with low hydraulic safety compared to alpine trees and osmotic properties connected to the species’ soil humidity requirements.


2021 ◽  

Explore a thorough and up to date overview of the current knowledge, developments and outstanding challenges in turbulent combustion and application. The balance among various renewable and combustion technologies are surveyed, and numerical and experimental tools are discussed along with recent advances. Covers combustion of gaseous, liquid and solid fuels and subsonic and supersonic flows. This detailed insight into the turbulence-combustion coupling with turbulence and other physical aspects, shared by a number of the world leading experts in the field, makes this an excellent reference for graduate students, researchers and practitioners in the field.


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