scholarly journals Effects of COVID-19 Lockdown on the Emotional and Behavioral Profiles of Preschool Italian Children with and without Familial Risk for Neurodevelopmental Disorders

2021 ◽  
Vol 11 (4) ◽  
pp. 477
Author(s):  
Chiara Cantiani ◽  
Chiara Dondena ◽  
Elena Capelli ◽  
Elena M. Riboldi ◽  
Massimo Molteni ◽  
...  
Keyword(s):  
Environmental Factors ◽  
Neurodevelopmental Disorders ◽  
Child Behavior Checklist ◽  
Ad Hoc ◽  
Negative Impact ◽  
Familial Risk ◽  
Parent Questionnaire ◽  
Behavioral Profiles ◽  
Containment Measures ◽  
Italian Children

The effects of COVID-19 containment measures on the emotional and behavioral development of preschoolers are not clear. We investigated them within an ongoing longitudinal project including typically developing children (TD) and children at high familial risk for neurodevelopmental disorders (HR-NDD) who were potentially more vulnerable. The study included ninety children aged 2–6 years (TD = 48; HR-NDD = 42). Before the emergency phase (T0), all children received a clinical assessment, including the parent questionnaire Child Behavior Checklist for Ages 1.5–5 (CBCL 1.5–5). The same questionnaire was filled out again during the emergency (T1), together with an ad-hoc questionnaire investigating environmental factors characterizing the specific period. Changes in the CBCL profiles between T0 and T1 were evaluated. Overall, irrespective of familial risk, the average T-scores on specific CBCL scales at T1 were higher than at T0. Associations emerged between delta scores reflecting worsening scores on specific CBCL scales and clinical and environmental factors. Our results confirmed the negative impact of the lockdown on preschool children’s emotional/behavioral profiles, and highlight the need for strategic approaches in the age range of 2–6 years, especially for more susceptible children owing to environmental factors and pre-existing emotional problems.

scholarly journals The Premises of the Appearance of the Education Concept for Sustainable Development

2019 ◽  
Vol 25 (1) ◽  
pp. 241-244
Author(s):  
Elisabeta-Emilia Halmaghi ◽  
Ruxandra Moşteanu
Keyword(s):  
Sustainable Development ◽  
Environmental Factors ◽  
Negative Impact ◽  
Development Education ◽  
Sustainable Development Education ◽  
Education Concept

Abstract Paradoxically, the more educated and wealthier the society is, the greater the negative impact on the environment, because the consumption needs are higher, which leads to an increase in the pollution of the environmental factors. This leads us to the conclusion that, in order to achieve sustainable development, education of the population is not sufficient. The link between sustainable development and education is very complex, and the challenge faced by mankind is to educate the population to become a factor of change.

scholarly journals Relationship between the Socioeconomicsocio-Educational Context and Thecognitive Performance from WISC-IV Indexes

2017 ◽  
Vol 11 (2) ◽  
pp. 359
Author(s):  
Agustina Labin ◽  
Alejandra Taborda
Keyword(s):  
Working Memory ◽  
Public Schools ◽  
Environmental Factors ◽  
Extracurricular Activities ◽  
Maternal Education ◽  
Ad Hoc ◽  
School Level ◽  
Shared Environment ◽  
International Studies ◽  
Verbal Comprehension

Background: national and international studies attach particular importance to the average socio shared environment as an explanatory variable intellectual performance in psychometric test. Objetive: To analyze the relationship between maternal education, the number of books in the home, the initial school level and extracurricular activities such as measures of socioeconomic, educational and environmentally with cognitive production WISC-IV level. Method: We worked with 154 children as 6 to 12 who attend public schools in the city of San Luis (Argentina). A sociodemographic survey designed ad hoc and the Argentinian adapting Intelligence Scale for Children Wechsler were implemented. We used ANOVA and Student test to analyze the differences between the proposed variables and the WISC-IV. Results: We found associations between the ducational level of the mother and the production in verbal comprehension, perceptual reasoning, working memory and total IQ of their children. In addition, significant differences were found between the number of books available at home and the age of entry admission to initial school level with verbal comprehension, and total IQ; as well as perceptive reasoning and working memory and extracurricular activities, sports and/or language study, among other. Conclusion: the need to recognize the socio-environmental factors to develop a proper interpretation of the test production is ratified. In this context we propose an extended and integrated diagnostic destined to capture the complex plot by the combination of capacities from the stimulation provided by the environment and the development of specific abilities less influenced by environmental factors.

scholarly journals Impact of exposures to persistent endocrine disrupting compounds on the sperm methylome in regions associated with neurodevelopmental disorders

2021 ◽  
Author(s):  
Angela G. Maggio ◽  
Henry T. Shu ◽  
Benjamin I. Laufer ◽  
Hyeyeon Hwang ◽  
Chongfeng Bi ◽  
...  
Keyword(s):  
Gene Ontology ◽  
Environmental Factors ◽  
Neurodevelopmental Disorders ◽  
Endocrine Disrupting Compounds ◽  
Autism Spectrum ◽  
Risk Genes ◽  
Genome Wide ◽  
Endocrine Disrupting ◽  
Pathway Analyses ◽  
Elevated Exposure

AbstractBackgroundAlthough autism spectrum disorder (ASD) is among the most heritable of neurodevelopmental disorders, the rapidly rising prevalence of ASD suggests that environmental factors may interact with genetic risk for ASD. Environmental factors may impact both gene expression and phenotypes in ASD through epigenetic modifications that, in turn, could lead to intergenerational effects influencing risk for ASDs. Endocrine disrupting compounds (EDCs), such as the long-lived organochlorines, are of particular interest with respect to risk for autism because of their ability to interfere with sex hormones that have been implicated in the regulation of RORA, a dysregulated gene in ASD that is a master regulator of many other ASD risk genes.ObjectivesThe specific aims of this study are to: 1) investigate whether high versus low exposures to the persistent organochlorine 1,1-dichloro-2,2-bis(p-chlorophenyl)ethylene (DDE) are associated with differentially methylated regions (DMRs) in sperm from a Faroese cohort whose natural diet of pilot whale meat and blubber exposes them to higher than average levels of organic pollutants; 2) determine if genes associated with DDE DMRs are enriched for ASD risk genes; 3) identify pathways and functions over-represented among genes associated with DMRs.MethodsWhole genome bisulfite sequencing (WGBS) was used to identify genome-wide DMRs in sperm from individuals divided by high and low exposure levels. Gene ontology and pathway analyses were used to determine enrichment in functional relationships to ASD.ResultsGenes in DMRs not only could discriminate between high and low exposures to DDE, but also were enriched in autism risk genes. Gene ontology and pathway analyses of these genes show significant enrichment for neurodevelopmental processes frequently impacted by ASD.ConclusionResults of this study show that elevated exposure to certain organochlorines is associated with genome-wide DNA methylation patterns in sperm affecting genes involved in neurological functions and developmental disorders, including ASD.

scholarly journals QTL analysis and management of plant productivity in the precision agriculture

2020 ◽  
pp. 12-19
Author(s):  
Yu. V. Chesnokov
Keyword(s):  
Environmental Factors ◽  
Qtl Analysis ◽  
Precision Agriculture ◽  
Crop Production ◽  
Negative Impact ◽  
Molecular Genetic ◽  
Self Regulation ◽  
Agricultural Practices ◽  
Plant Productivity ◽  
Steady Increase

Modern crop cultivation technologies have reached the limits of “saturation” both in the ecological (environmental pollution, suppression of the mechanisms of its self-regulation), energy (exponential growth of irreplaceable energy costs for each additional unit of production), and in production. In this regard, environmental factors (air drought, frosts, active temperatures, etc.), which cannot be optimized, are becoming increasingly important in ensuring a steady increase in the yield of cultivated plant forms. In recent decades, more and more attention has been paid to technogenic and biological systems of agriculture, based on the ecologization and biologization of the intensification processes of adaptive crop production. Such approaches are the precision agriculture system (PA) and QTL analysis. Using these approaches allows not only to ensure a steady increase in productivity due to the combined use of the advantages of precision farming and molecular genetic assessment, including the creation of new forms and varieties that are responsive to РА agricultural practices, but also to level the negative impact of abiotic and biotic environmental factors that limit the size and quality of the crop as well as plant productivity. It is shown that the strategy of adaptive intensification of crop production through the use of the TK system and QTL analysis approaches is not alternative to existing farming systems, however, it focuses modern agriculture on the growth of knowledge-intensive agricultural production as a whole. An analysis of the causes under consideration, the current unfavorable trends in modern crop production and agriculture, clearly shows their scale and long-term nature, and therefore the inevitability of the search for new priorities for intensification of crop production and agriculture, providing a qualitatively new stage of their development in the interests of man.

scholarly journals Impact of COVID-19 on the trade of goods and services in Spain

2021 ◽  
Vol ahead-of-print (ahead-of-print) ◽  
Author(s):  
Asier Minondo
Keyword(s):  
Negative Impact ◽  
The European Union ◽  
Firm Level ◽  
Health Crisis ◽  
Content Type ◽  
Goods And Services ◽  
Containment Measures ◽  
Trade Of Services ◽  
The Impact

Purpose This paper aims to analyze the impact of COVID-19 on the trade of goods and services in Spain. Design/methodology/approach This paper uses monthly trade data at the product, region and firm level. Findings The COVID-19 crisis has led to the sharpest collapse in the Spanish trade of goods and services in recent decades. The containment measures adopted to arrest the spread of the virus have caused an especially intense fall of trade in services. The large share of transport equipment, capital goods, products that are consumed outdoors (i.e., outdoor goods) and tourism in Spanish exports has made the COVID-19 trade crisis more intense in Spain than in the rest of the European Union. Practical implications The nature of the collapse suggests that trade in goods can recover swiftly when the health crisis ends. However, COVID-19 may have a long-term negative impact on the trade of services that rely on the movement of people. Originality/value It contributes to understand how COVID-19 has affected the trade in goods and services in Spain.

scholarly journals KAJIAN KRIMINOLOGI PEREDARAN NARKOTIKA (SEBUAH STUDI DI KABUPATEN ACEH TIMUR)

2019 ◽  
Vol 5 (1) ◽  
Author(s):  
Muammar
Keyword(s):  
Environmental Factors ◽  
Development Process ◽  
Negative Impact ◽  
National Development ◽  
Deterrent Effect ◽  
Youth Organizations ◽  
The People ◽  
The Republic ◽  
Work Family ◽  
The Impact

The impact of globalization has penetrated throughout the civilization of the nations of the world, running so fast. Especially very influential on changes in various lines of life. Related to this is the issue of increasing narcotics abuse and narcotics illicit trafficking which has created conditions that have hindered the development process and weakened civilization. Eradication of narcotics distribution is a national problem, because it has a negative impact that can damage and threaten the lives of the people, nation and state and can hamper the national development process. The rise of narcotics abuse does not only occur in big cities, but has reached small cities in all ten regions of the Republic of Indonesia, including East Aceh Regency. The increasingly diverse lifestyle of the people due to the influence of globalization also contributes to the increasing circulation of narcotics in East Aceh District. This certainly must receive serious attention, because if we look at what is happening in East Aceh District and several other regions in Indonesia, the crime of narcotics distribution from time to time always increases which in the end is increasingly unsettling the community, so before these things increase In East Aceh District, an effective solution must be found to eradicate it. Factors that cause a person to commit a narcotics crime in East Aceh Regency are due to economic factors where a person needs money to live and the difficulty of getting work, family environmental factors, social environmental factors and availability / lack of supervision factors. Efforts in tackling narcotics circulation in East Aceh district involve many parties, including: firstly, pre-emptive efforts by providing counseling in the community and schools about narcotics carried out by the police in tackling narcotics crime in East Aceh District. Second, preventive measures (prevention) by conducting raids and patrols routinely, providing oversight of the association and positive activities carried out by the police, prosecutors, religious leaders, community leaders and youth organizations. The third repressive effort (action) which aims to provide a deterrent effect on the perpetrators of drug trafficking crimes involving all law enforcement officials ranging from the Police, Attorney and District Courts and Detention Houses.Keywords: Crimonology, Narcotics Circulation. 

THE ECOLOGICAL FACTORS AND HUMAH HEALTH

2019 ◽  
Vol 49 ◽  
pp. 148-149
Author(s):  
Javakhadze R. ჯავახაძე რ. ◽  
Turmanauli M. თურმანაული მ. ◽  
Kverenchkhiladze R. კვერენჩხილაძე რ. ◽  
Chikovani A. ჩიქოვანი ა. ◽  
Arabidze M. არაბიძე მ. ◽  
...  
Keyword(s):  
Environmental Factors ◽  
Disease Prevention ◽  
Negative Impact ◽  
Ecological Factors ◽  
Well Being ◽  
Significant Rise ◽  
Factors Affecting ◽  
The Public ◽  
Safe Environment ◽  
Global Problems

One of the actual global problems of mankind is an environmental pollution and its negative impact on a population’s health, that is the basis of existence of each human being and the entire state. The purpose of this article is to inform the public about the environmental factors affecting human health and its causes.As there is significant rise of ecological diseases, in many countries worldwide during the last years a great attention is paid to the legal side of environmental protection. Public well being is determined by ensuring its sanitaryepidemiological conditions,safe environment and disease prevention.

scholarly journals Autism spectrum disorder at the crossroad between genes and environment: contributions, convergences, and interactions in ASD developmental pathophysiology

2020 ◽  
Vol 11 (1) ◽  
Author(s):  
Cristina Cheroni ◽  
Nicolò Caporale ◽  
Giuseppe Testa
Keyword(s):  
Autism Spectrum Disorder ◽  
Environmental Factors ◽  
Neurodevelopmental Disorders ◽  
Chemical Exposure ◽  
Autism Spectrum ◽  
Synaptic Function ◽  
Spectrum Disorder ◽  
Regulatory Pathways ◽  
Genes And Environment ◽  
Analytical Approaches

Abstract The complex pathophysiology of autism spectrum disorder encompasses interactions between genetic and environmental factors. On the one hand, hundreds of genes, converging at the functional level on selective biological domains such as epigenetic regulation and synaptic function, have been identified to be either causative or risk factors of autism. On the other hand, exposure to chemicals that are widespread in the environment, such as endocrine disruptors, has been associated with adverse effects on human health, including neurodevelopmental disorders. Interestingly, experimental results suggest an overlap in the regulatory pathways perturbed by genetic mutations and environmental factors, depicting convergences and complex interplays between genetic susceptibility and toxic insults. The pervasive nature of chemical exposure poses pivotal challenges for neurotoxicological studies, regulatory agencies, and policy makers. This highlights an emerging need of developing new integrative models, including biomonitoring, epidemiology, experimental, and computational tools, able to capture real-life scenarios encompassing the interaction between chronic exposure to mixture of substances and individuals’ genetic backgrounds. In this review, we address the intertwined roles of genetic lesions and environmental insults. Specifically, we outline the transformative potential of stem cell models, coupled with omics analytical approaches at increasingly single cell resolution, as converging tools to experimentally dissect the pathogenic mechanisms underlying neurodevelopmental disorders, as well as to improve developmental neurotoxicology risk assessment.

scholarly journals Evaluation Research of Green Innovation Efficiency in China’s Heavy Polluting Industries

2019 ◽  
Vol 12 (1) ◽  
pp. 146 ◽  
Author(s):  
Zhong Fang ◽  
Hua Bai ◽  
Yuriy Bilan
Keyword(s):  
Environmental Factors ◽  
Negative Impact ◽  
Environmental Regulations ◽  
Empirical Test ◽  
Evaluation Model ◽  
Evaluation Research ◽  
Green Innovation ◽  
The Sustainable Development ◽  
Regulation Policy ◽  
The Impact

Recently, green innovation efficiency, which considers innovation and environmental factors, is gradually becoming important for the sustainable development of Chinese heavy polluting industries because of the increasing strictness in China’s environmental regulations. Previous studies ignore the impact of external environmental factors on the efficiency of green industry innovation and fail to explain the complex relationship between environmental and technical efficiency fully. Therefore, a non-radial directional distance function-data envelopment analysis (DDF-DEA) three-stage green innovation efficiency evaluation model was constructed to measure the green innovation efficiency of China’s heavy polluting industries objectively and explore the impact mechanism of external factors. Then, the aforementioned model was used to conduct an empirical test on China’s heavy polluting industries. Results indicate that the green innovation efficiency of heavy polluting industries is generally low in China, and the entire industry is in the transitional stage of “effective innovation but not green.” The uncertainty of the effect of the environmental regulation policy, the over-reliance on external technologies, and the scale diseconomies of industries, which are the key factors in improving the green innovation efficiency of China’s heavy polluting industries, have a significant negative impact on green innovation efficiency. The conclusions of this study can provide a useful reference for China and other emerging markets to formulate reasonable environmental regulations and green transition of heavy polluting industries.

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