scholarly journals Prevention and Control of Foodborne Diseases in Middle-East North African Countries: Review of National Control Systems

2019 ◽  
Vol 17 (1) ◽  
pp. 70 ◽  
Author(s):  
Dima Faour-Klingbeil ◽  
Ewen C. D. Todd
Keyword(s):  
Food Safety ◽  
Middle East ◽  
Control Systems ◽  
Public Health Problem ◽  
Building Blocks ◽  
International Standards ◽  
Foodborne Diseases ◽  
Management Approach ◽  
Global Public Health ◽  
Food Control

Foodborne diseases continue to be a global public health problem with an estimated 600 million people falling ill annually. In return, international standards are becoming stricter which poses challenges to food trade. In light of the increasing burden of foodborne diseases, many countries in the Middle East and North Africa (MENA) region have upgraded their food laws and undertaken changes to the organizational structure of their regulatory institutions to maintain or expand international export activities, tighten control on local and imported products, and protect consumers’ health. However, until this date, the published information on the regional health burdens of foodborne diseases is very limited and it is not clear whether the recent changes will serve towards science-based and effective preventive functions and the adoption of the risk management approach. In this review, we summarize the recent food safety issues and the national food control systems of selected countries in the region although we were challenged with the scarcity of information. To this end, we examined the national food safety systems in the context of the five essential elements of the FAO/WHO Guidelines for Strengthening National Food Control Systems. These five elements—food law and regulations; food control management; inspection services; laboratory services; food monitoring; and epidemiological data, information, education, communication, and training—constitute the building blocks of a national food control system, but could also serve as tools to assess the effectiveness of the systems.

scholarly journals The burden of foodborne diseases reducing ways

2019 ◽  
Vol 50 (1) ◽  
pp. 34-39
Author(s):  
T.L. Kolodnitska ◽  
V.O. Selezniova
Keyword(s):  
Food Safety ◽  
Addis Ababa ◽  
Private Investment ◽  
Foodborne Diseases ◽  
Global Public Health ◽  
Scientific Publications ◽  
Basic Principles ◽  
Accurate Picture ◽  
Food Safety And Quality

Introduction. The burden of foodborne diseases is increasingly attracting WHO attention and heightening the necessity of international global public health commitments. The Aim of the Study is to analyze and summarize the existing national and international experience in reducing the burden of foodborne diseases on the basis of studying legislative and regulatory documents, sources of statistical data, scientific publications and materials of the First FAO/WHO/AU International Food Safety Conference Addis Ababa, 12–13 February 2019. Materials and Methods. The bibliosemantic and analytical methods have been used. Results and discussion. It is established that today, the lack of data about the burden of foodborne diseases not only does not allow to get an accurate picture of the current situation, but also complicates the evaluation of the effectiveness and resulting quality of preventive measures and strategies. In recent years, Ukraine has witnessed a sharp deterioration in the food safety and quality situation due to the demonopolization of the food industry, increased volumes of supplies from abroad, weakening of the control over the production and sale of food products. Unresolved issues remain regarding the level of harmonization of Ukrainian legislation with European norms, which is currently insufficient. Conclusions. In order to reduce the burden of foodborne diseases, the basic principles recommended by the WHO should be taken into consideration: orientation of the measures being implemented to the future, their preventive character, capacity-building in foundational spheres, the integrating efforts and the stimulation of private investment.

Gold nanoparticle based colorimetric sensor for rapid detection of Yersinia enterocolitica serotype O:8 in food samples

2022 ◽  
Author(s):  
lu zeng ◽  
Xin-Xin Xu ◽  
Hongliu Ding ◽  
Shanshan Song ◽  
Liguang Xu ◽  
...  
Keyword(s):  
Public Health ◽  
Food Safety ◽  
Gold Nanoparticle ◽  
Yersinia Enterocolitica ◽  
Rapid Detection ◽  
Food Samples ◽  
Detection Methods ◽  
Foodborne Diseases ◽  
Global Public Health ◽  
Serotype O

Foodborne diseases from Yersinia enterocolitica serotype O:8 represent global public health problems. We need rapid Y. enterocolitica O:8 detection methods to ensure food safety. In this study, we developed a...

scholarly journals Unravelling the history of hepatitis B virus genotypes A and D infection using a full-genome phylogenetic and phylogeographic approach

eLife ◽  
2018 ◽  
Vol 7 ◽  
Author(s):  
Evangelia-Georgia Kostaki ◽  
Timokratis Karamitros ◽  
Garyfallia Stefanou ◽  
Ioannis Mamais ◽  
Konstantinos Angelis ◽  
...  
Keyword(s):  
Hepatitis B Virus ◽  
Middle East ◽  
Hepatitis B ◽  
Public Health Problem ◽  
Sub Saharan Africa ◽  
Global Public Health ◽  
B Virus ◽  
Putative Origin ◽  
Sub Saharan ◽  
Regional Clustering

Hepatitis B virus (HBV) infection constitutes a global public health problem. In order to establish how HBV was disseminated across different geographic regions, we estimated the levels of regional clustering for genotypes D and A. We used 916 HBV-D and 493 HBV-A full-length sequences to reconstruct their global phylogeny. Phylogeographic analysis was conducted by the reconstruction of ancestral states using the criterion of parsimony. The putative origin of genotype D was in North Africa/Middle East. HBV-D sequences form low levels of regional clustering for the Middle East and Southern Europe. In contrast, HBV-A sequences form two major clusters, the first including sequences mostly from sub-Saharan Africa, and the second including sequences mostly from Western and Central Europe. Conclusion: We observed considerable differences in the global dissemination patterns of HBV-D and HBV-A and different levels of monophyletic clustering in relation to the regions of prevalence of each genotype.

scholarly journals A Stress Management Approach: An Insight into Yoga

2021 ◽  
Vol 9 (VII) ◽  
pp. 2046-2048
Author(s):  
Dr. Reemani Verma
Keyword(s):  
Psychological Health ◽  
Age Groups ◽  
Public Health Problem ◽  
Modern Society ◽  
Management Approach ◽  
Global Public Health ◽  
Physical Problems ◽  
The People ◽  
Global Public Health Problem

Stress, a global public health problem, is a widely prevalent phenomenon in modern society and may account for deprived quality of life, lower mental health, reduced work efficiency, greater suffering and increased physical problems. In an age of a highly dynamic and competitive world, man is exposed to all kinds of stresses that can affect him in all realms of life. To manage or reduce stress, several popular approaches are there and Yoga is one such approach which now a days is considered to be the best and most effective method/technique to reduce stress levels in the people of all age groups. Yoga brings together physical and mental disciplines that may help one achieve peacefulness of body and mind. It can help one relax and manage stress and anxiety. This paper attempts to highlight the psychological health benefits of yoga and also intends to analyse the various poses, postures included in yoga exercises that are helpful in managing different levels of stress in the people of all age groups.

scholarly journals Developing and maintaining national food safety control systems: Experiences from the WHO African region

2012 ◽  
Vol 12 (52) ◽  
pp. 6291-6304
Author(s):  
L Mwamakamba ◽  
◽  
P Mensah ◽  
A Kwakye Takyiwa ◽  
J Darkwah-Odame ◽  
...  
Keyword(s):  
Food Safety ◽  
Control Systems ◽  
Food Control ◽  
African Region ◽  
African Countries ◽  
Safety Control ◽  
Laboratory Services ◽  
Safety Systems ◽  
National Information ◽  
Development Structure

The establishment of effective food safety systems is pivotal to ensuring the safety of the national food supply as well as food products for regional and international trade. The development, structure and implementation of modern food safety systems have been driven over the years by a number of developments. These developments include: a reorientation of quality assurance protocols; emphasis on the development of integrated and holistic food safety systems with a farm-to-table approach; increased recognition of the respective roles of the different stakeholders along the food chain; increased food trade coupled with obligations under trade agreements; and advances in the control of foodborne hazards. At its core, a modern food safety system includes enabling food laws, policies, regulations and standards; mechanisms for coordination; operational food inspection and laboratory services as well as national information, education and communication programmes. While progress has been made in some countries in the WHO African Region at modernizing their food safety systems, many others are still grappling with the basics for development of effective food control systems. The traditional food control systems in a number of African countries do not provide the concerned agencies with a clear mandate and authority to prevent food safety problems. Effective food control in a number of these countries is undermined by a number of challenges including limited awareness about food safety, inadequate enabling policy, outdated legislation and regulations; inadequate coordination; and inadequate capacity and resources for food safety. This paper reviews the components of a modern national food safety control system and examines efforts at strengthening national food safety control systems in the African Region. It includes experiences from countries that have made efforts at strengthening their national food safety control systems in view of current developments. The paper further discusses some of the challenges of food control systems in the Region and prospects for improvements. It concludes by suggesting the way forward for improving national food safety control systems in the Region.

Modulation of the drug resistance by Platonia insignis Mart. extract, ethyl acetate fraction and Morelloflavone/Volkensiflavone (biflavonoids) in Staphylococcus aureus strains overexpressing efflux pump genes

2020 ◽  
Vol 21 ◽  
Author(s):  
Andressa Kelly Ferreira e Silva ◽  
Antonielly Campinho dos Reis ◽  
Emanuelly Elanny Andrade Pinheiroc ◽  
Jonas Nascimento de Sousa ◽  
Felipe Araújo de Alcântara Oliveira ◽  
...  
Keyword(s):  
Natural Products ◽  
Ethyl Acetate ◽  
Native Species ◽  
Efflux Pump ◽  
Public Health Problem ◽  
Ethyl Acetate Fraction ◽  
Multidrug Resistant ◽  
Global Public Health ◽  
Minimal Inhibitory Concentrations ◽  
Subinhibitory Concentrations

Background: Microbial resistance to antibiotics is a global public health problem, which requires urgent attention. Platonia insignis is a native species from the eastern Brazilian Amazon, used in the treatment of burns and wounds. Objectives: To evaluate the antimicrobial activity of the hydroalcoholic extract of P. insignis (PIHA), the ethyl acetate fraction (PIAE), and its subfraction containing a mixture of biflavonoids (BF). Moreover, the effect of these natural products on the antibiotic activity against S. aureus strains overexpressing efflux pump genes was also evaluated. Methods: Minimal inhibitory concentrations were determined against different species of microorganisms. To evaluate the modulatory effect on the Norfloxacin-resistance, the MIC of this antibiotic was determined in the absence and presence of the natural products at subinhibitory concentrations. Inhibition of the EtBr efflux assays were conducted in the absence or presence of the natural products. Results: PIHA showed a microbicidal effect against S. aureus and C. albicans, while PIAE was bacteriosctatic for S. aureus. PIAE and BF at subinhibitory concentrations were able to reduce the MIC of Norfloxacin acting as modulating agents. BF was able to inhibit the efflux of EtBr efflux in S. aureus strains overexpressing specific efflux pump genes. Conclusion: P. inignisis a source of efflux pump inhibitors, including volkensiflavone and morelloflavone which were able to potentiate the Norfloxacin activity by NorA inhibition, being also able to inhibit QacA/B, TetK and MsrA. Volkensiflavone and morelloflavone could be used as adjuvant in the antibiotic therapy of multidrug resistant S. aureus strains overexpressing efflux pumps.

4H-1,3-Benzothiazin-4-one a Promising Class Against MDR/XDR-TB

2019 ◽  
Vol 19 (8) ◽  
pp. 567-578 ◽  
Author(s):  
Marcus Vinicius Nora de Souza ◽  
Thais Cristina Mendonça Nogueira
Keyword(s):  
Treatment Time ◽  
Public Health Problem ◽  
New Drugs ◽  
Global Public Health ◽  
Synthesis Mechanism ◽  
Highly Active ◽  
Latent Disease ◽  
Resistant Strains ◽  
Chemical Class ◽  
Global Public Health Problem

Nowadays, tuberculosis (TB) is an important global public health problem, being responsible for millions of TB-related deaths worldwide. Due to the increased number of cases and resistance of Mycobacterium tuberculosis to all drugs used for the treatment of this disease, we desperately need new drugs and strategies that could reduce treatment time with fewer side effects, reduced cost and highly active drugs against resistant strains and latent disease. Considering that, 4H-1,3-benzothiazin-4-one is a promising class of antimycobacterial agents in special against TB-resistant strains being the aim of this review the discussion of different aspects of this chemical class such as synthesis, mechanism of action, medicinal chemistry and combination with other drugs.

Application of Inherent Risk of Contagion (IRC) framework & modelling to aid local Covid-19 response & mitigation: Viewpoint (Preprint)

2020 ◽  
Author(s):  
Helmi Zakariah ◽  
Fadzilah bt Kamaluddin ◽  
Choo-Yee Ting ◽  
Hui-Jia Yee ◽  
Shereen Allaham ◽  
...  
Keyword(s):  
Public Health ◽  
Public Health Problem ◽  
Analytical Framework ◽  
Vulnerable Population ◽  
Contact Tracing ◽  
Global Public Health ◽  
Inherent Risk ◽  
Transmission Area ◽  
Current Outbreak ◽  
Novel Coronavirus

UNSTRUCTURED The current outbreak of coronavirus disease 2019 (COVID-19) caused by the novel coronavirus named SARS-CoV-2 has been a major global public health problem threatening many countries and territories. Mathematical modelling is one of the non-pharmaceutical public health measures that plays a crucial role for mitigating the risk and impact of the pandemic. A group of researchers and epidemiologists have developed a machine learning-powered inherent risk of contagion (IRC) analytical framework to georeference the COVID-19 with an operational platform to plan response & execute mitigation activities. This framework dataset provides a coherent picture to track and predict the COVID-19 epidemic post lockdown by piecing together preliminary data on publicly available health statistic metrics alongside the area of reported cases, drivers, vulnerable population, and number of premises that are suspected to become a transmission area between drivers and vulnerable population. The main aim of this new analytical framework is to measure the IRC and provide georeferenced data to protect the health system, aid contact tracing, and prioritise the vulnerable.

Perceived Experiences of Community Violence Among Adolescents: A School Survey From Rio de Janeiro, Brazil

2021 ◽  
pp. 088626052110051
Author(s):  
Claudia L. de Moraes ◽  
Érika B. dos Santos ◽  
Michael E. Reichenheim ◽  
Stella R. Taquette ◽  
Luciane Stochero ◽  
...  
Keyword(s):  
Public Schools ◽  
Community Violence ◽  
Rio De Janeiro ◽  
Public Health Problem ◽  
Cross Sectional Study ◽  
Global Public Health ◽  
Cross Sectional ◽  
Interpersonal Aggression ◽  
Adolescent Students ◽  
Management Actions

Community violence (CV) is a global public health problem due to its high frequency and severe consequences. Although CV is one of the leading causes of death among adolescents, little is known about the everyday CV situations that do not lead to death. This study aimed to estimate the frequency of exposure to and involvement in CV situations among adolescent students from public and private schools in the city of Rio de Janeiro, Brazil. This was a cross-sectional study of 693 individuals in their second year of high school selected through stratified multistage random sampling. Information about their exposure to and involvement in CV was collected through a self-completed multidimensional questionnaire in the classrooms. For approximately 30% of the adolescents, someone close to them had been murdered, and 40% had already seen the corpse of a victim of homicide. Seventeen percent reported having been directly involved in CV situations. Approximately 38%, 13%, and 25% had been victims of robberies, interpersonal aggression, and death threats to either themselves or their relatives, respectively. Many of these situations occurred more than once. In general, CV was more frequently reported by boys and by those who did not live with both parents. Adolescents from higher economic classes experienced more interpersonal aggression and felt a greater need to carry a gun. Those who belonged to the lower economic classes and studied in public schools were more exposed to lethal violence than other students. The results call attention to the very high percentage of adolescent students that are involved in CV situations as well as to the differences in violence rates among population subgroups. Such findings should be considered when planning CV prevention and management actions in schools and other socialization spaces for adolescents.

scholarly journals Associations between gestational diabetes mellitus and the neurodevelopment of offspring from 1 month to 72 months: study protocol for a cohort study

BMJ Open ◽  
2020 ◽  
Vol 10 (11) ◽  
pp. e040305
Author(s):  
Chao Li ◽  
Ping Zhou ◽  
Yixi Cai ◽  
Bin Peng ◽  
Yongfang Liu ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Cohort Study ◽  
Gestational Diabetes ◽  
Gestational Diabetes Mellitus ◽  
Public Health Problem ◽  
Multiple Linear Regression Model ◽  
Preschool Age ◽  
Control Group ◽  
Global Public Health ◽  
Open Access Journals

IntroductionGestational diabetes mellitus (GDM) is a common gestational disease and an important global public health problem. GDM may affect the short-term and long-term health of offspring, but the associations between GDM and the neurodevelopment of offspring of mothers with GDM (OGDM) are still unclear, and studies based on the Chinese population are lacking. We aim to determine the associations between GDM and the neurodevelopment of OGDM by studying a cohort of OGDM and offspring of non-GDM mothers.Methods and analysisThe single-centre prospective cohort study is being conducted in China over 7 years. A total of 490 OGDM (GDM group) and 490 fromof healthy mothers (control group) will be enrolled during the same period. Baseline characteristics, neuropsychological development scores and clinical data at specific time points (at 0, 1, 3, 6, 12, 24, 36, 48, 60 and 72 months old) will be collected from the children in both groups until the age of 6 years. The associations between GDM and the neurodevelopment of OGDM from infancy to preschool age will be analysed using a multiple linear regression model adjusted for confounders. In addition, we will compare longitudinal data to further assess the effects of GDM on neurodevelopmental trajectories.Ethics and disseminationThe study has been approved by the Ethics Committee of the Children’s Hospital of Chongqing Medical University (Approval Number: (2019) Institutional Review Board (IRB) (STUDY) No. 85). The findings of this study will be disseminated through open access journals, peer-reviewed journals and scientific meetings.Trial registration numberNCT03997396.

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