scholarly journals Effects of Untreated Drinking Water at Three Indigenous Yaqui Towns in Mexico: Insights from a Murine Model

2021 ◽  
Vol 18 (2) ◽  
pp. 805
Author(s):  
Sofia Navarro-Espinoza ◽  
Aracely Angulo-Molina ◽  
Diana Meza-Figueroa ◽  
Guillermo López-Cervantes ◽  
Mercedes Meza-Montenegro ◽  
...  
Keyword(s):  
Drinking Water ◽  
Hematological Parameters ◽  
Indigenous Communities ◽  
Early Response ◽  
Statistical Correlation ◽  
Histological Changes ◽  
Untreated Water ◽  
Northwestern Mexico ◽  
The Brain ◽  
Insight Into

Background: Reports in a northwestern Mexico state linked arsenic (As) in drinking water to DNA damage in people from indigenous communities. However, this correlation remains under discussion due to unknown variables related to nutrition, customs, and the potential presence of other metal(oid)s. Methods: To determine this association, we sampled water from three Yaqui towns (Cócorit, Vícam, and Pótam), and analyzed the metals by ICP-OES. We exposed four separate groups, with five male CD-1 mice each, to provide further insight into the potential effects of untreated drinking water. Results: The maximum concentrations of each metal(oid) in µg·L−1 were Sr(819) > Zn(135) > As(75) > Ba(57) > Mo(56) > Cu(17) > Al(14) > Mn(12) > Se(19). Histological studies revealed brain cells with angulation, satellitosis, and reactive gliosis with significant statistical correlation with Mn and As. Furthermore, the liver cells presented hepatocellular degeneration. Despite the early response, there is no occurrence of both statistical and significative changes in hematological parameters. Conclusions: The obtained results provide experimental insights to understand the potential effects of untreated water with low As and Mn contents in murine models. This fact is noteworthy because of the development of histological changes on both the brain and liver at subchronic exposure.

scholarly journals INSIGHT INTO COMPLETE BLOOD COUNT IN MALIGNANCIES

2019 ◽  
pp. 1-2
Author(s):  
Gayathri M. N
Keyword(s):  
Immune System ◽  
Tumor Microenvironment ◽  
Blood Count ◽  
Complete Blood Count ◽  
Metastatic Cancer ◽  
Hematological Parameters ◽  
Statistical Correlation ◽  
Physiological Process ◽  
Host Interaction ◽  
Insight Into

It is very well known that the tumor-host interaction is not limited to the tumor microenvironment but to also alter the entire physiological process to help the development and progression of cancer. Our immune system does not escape from the clutches of the cancer, i.e altered hematological parameters can influence the progression of cancer and vice versa. With this in mind we conducted this study in the Department of Pathology MMC&RI with an attempt to reveal the pattern of complete blood count in malignancies and their difference in localized and metastatic cancer. All the cases included in this study were the ones referred to Cytopatholgy, and diagnosed with cancer. There was significant statistical correlation between the various hematological parameters and the metastatic cancers implying their use to predict the tumor behavior

scholarly journals Drinking Water Consumption Patterns: An Exploration of Risk Perception and Governance in Two First Nations Communities

2020 ◽  
Vol 12 (17) ◽  
pp. 6851
Author(s):  
Neal Spicer ◽  
Brenda Parlee ◽  
Molly Chisaakay ◽  
Doug Lamalice
Keyword(s):  
Drinking Water ◽  
Risk Perception ◽  
First Nations ◽  
Water Consumption ◽  
Local Community ◽  
Indigenous Communities ◽  
Bottled Water ◽  
Consumption Patterns ◽  
First Nation ◽  
Individual Risk

Many Indigenous communities across Canada suffer from the lack of access to clean drinking water; ensuring individuals and communities have safe water to drink either from their home or from their local environment requires the consideration of multiple factors including individual risk perception. In collaboration with local leaders, semi-structured interviews (n = 99) were conducted over a two-year period in the Dene Tha’ First Nation and Kátł’odeeche First Nation to unpack the issue of risk perception and its meaning to local community members. These local metrics of risk perception including smell, taste, safety, health fears and level of concern were then used to explore patterns in other data on drinking water consumption patterns and bottled water use. The results are consistent with previous research related to water insecurity and indicate that both communities consume more bottled water than the average Canadian. Results also varied by jurisdiction; those in Alberta indicated much higher levels of concern and a greater degree of bottled water consumption.

scholarly journals Effect of Acetic Acid and Sodium Bicarbonate Supplemented to Drinking Water on Water Quality, Growth Performance, Organ Weights, Cecal Traits and Hematological Parameters of Young Broilers

Animals ◽  
2021 ◽  
Vol 11 (7) ◽  
pp. 1865
Author(s):  
Yordan Martínez ◽  
Cristopher Isaac Almendares ◽  
Cristhian José Hernández ◽  
Mavir Carolina Avellaneda ◽  
Ana Melissa Urquía ◽  
...  
Keyword(s):  
Water Quality ◽  
Drinking Water ◽  
Acetic Acid ◽  
Sodium Bicarbonate ◽  
Growth Performance ◽  
Hematological Parameters ◽  
Relative Weight ◽  
Biological Response ◽  
Blood Parameters ◽  
Organ Weights

To evaluate the effect of acetic acid and sodium bicarbonate supplemented to drinking water on water quality, growth performance, relative organ weights, cecal traits and hematological parameters of broilers, a total of 456 one-day-old Cobb MV × Cobb 500 FF mixed broilers were randomly placed in three experimental treatments, with four replicates per treatment and 38 birds per replicate, for 10 days. The treatments consisted of the use of acetic acid (0.4%; T1) as acidifier, an apparently neutral pH (T2) and sodium bicarbonate (1%; T3) as alkalizer of the drinking water. T3 showed the highest values (p < 0.05) for total dissolved solids, electrical conductivity, salinity and pH. T1 and T2 showed the same productive response (p > 0.05); however, T3 decreased (p < 0.05) body weight, feed intake and the relative weight of the pancreas and immune organs and increased (p < 0.05) water intake, mortality and relative weight of the heart and liver. Likewise, T3 increased (p < 0.05) the cecal pH, although without changes for the cecal lactic cecal bacteria count and blood parameters (p > 0.05). The acid pH of the drinking water had no effect on the biological response of broilers compared to T2; however, the T3 provoked high mortality, ascites, low productivity and abnormal growth of some organs.

scholarly journals Sodium Hypochlorite Treatment: The Impact on Bacteria and Endotoxin Concentrations in Drinking Water Pipes of A Pig Nursery

Agriculture ◽  
2020 ◽  
Vol 10 (3) ◽  
pp. 86
Author(s):  
Regina Böger ◽  
Karl Rohn ◽  
Nicole Kemper ◽  
Jochen Schulz
Keyword(s):  
Water Quality ◽  
Drinking Water ◽  
Sodium Hypochlorite ◽  
Coliform Bacteria ◽  
Treated Water ◽  
Water Pipes ◽  
Pseudomonas Spp ◽  
Untreated Water ◽  
The Impact ◽  
Total Bacteria

Poor drinking water quality can affect pigs’ health and performance. The disinfection of water may enhance microbial water quality. In this study, bacteria and endotoxins in sodium hypochlorite-treated and -untreated water from one pig nursery were analyzed. Water samples were taken from incoming water and from compartments with treated and untreated water at the beginning and end of pipes and from nipples. The farm was visited 14 times to measure total bacteria counts and concentrations of Pseudomonas spp. and endotoxins. Additionally, the occurrence of coliform bacteria was analyzed. A mixed model analysis revealed significant reductions in total bacteria counts and Pseudomonas spp. in treated water at the beginning of pipes and at nipple drinkers. The differences between bacteria concentrations at the end of pipes had no clear trend. Endotoxin concentrations were approximately equal at the beginning of pipes and at nipple drinkers but were found to have differences at the end of pipes. The occurrence of coliform bacteria was significantly reduced in treated water. The application of sodium hypochlorite can significantly reduce bacteria in water pipes. Endotoxin concentrations were mostly unaffected by water treatment. Disinfection of the dead-end pipe sections failed, and thus these parts should be regarded as potential contamination sources.

Effects of the SNAP25 on Integration Ability of Brain Functions in Children With ADHD

2020 ◽  
pp. 108705472096456
Author(s):  
Yue Yang ◽  
Gang Peng ◽  
Hongwu Zeng ◽  
Diangang Fang ◽  
Linlin Zhang ◽  
...  
Keyword(s):  
Time Window ◽  
Precentral Gyrus ◽  
Children With Adhd ◽  
Brain Functions ◽  
Lingual Gyrus ◽  
Window Method ◽  
Central Gyrus ◽  
The Right ◽  
The Brain ◽  
Insight Into

Objective: The present study aimed to examine the effects of SNAP25 on the integration ability of intrinsic brain functions in children with ADHD, and whether the integration ability was associated with working memory (WM). Methods: A sliding time window method was used to calculate the spatial and temporal concordance among five rs-fMRI regional indices in 55 children with ADHD and 20 healthy controls. Results: The SNAP25 exhibited significant interaction effects with ADHD diagnosis on the voxel-wise concordance in the right posterior central gyrus, fusiform gyrus and lingual gyrus. Specifically, for children with ADHD, G-carriers showed increased voxel-wise concordance in comparison to TT homozygotes in the right precentral gyrus, superior frontal gyrus, postcentral gyrus, and middle frontal gyrus. The voxel-wise concordance was also found to be related to WM. Conclusion: Our findings provided a new insight into the neural mechanisms of the brain function of ADHD children.

scholarly journals How Does the Arctic Council Support Conservation of Arctic Biodiversity?

2020 ◽  
Vol 12 (12) ◽  
pp. 5042
Author(s):  
Tom Barry ◽  
Brynhildur Daviðsdóttir ◽  
Níels Einarsson ◽  
Oran R. Young
Keyword(s):  
Climate Change ◽  
Sustainable Development ◽  
Environmental Protection ◽  
Indigenous Communities ◽  
The Arctic ◽  
Arctic Council ◽  
National Interests ◽  
Conflicting Demands ◽  
Agent Of Change ◽  
Insight Into

The Arctic Council is an intergovernmental forum promoting cooperation, coordination and interaction among Arctic states, indigenous communities, and peoples on issues of common importance. The rising geo-political importance of the Arctic and the onset of climate change has resulted in the Council becoming a focus of increasing interest from both inside and beyond the Arctic. This has resulted in new demands placed on the Council, attracting an increasing number of participants, and instigating a period of transformation as Arctic states work to find a way to balance conflicting demands to improve the Council’s effectiveness and take care of national interests. This paper considers whether, during this time of change, the Council is having an impact on the issues it was formed to address, i.e., environmental protection and sustainable development. To provide answers, it looks at how the Council reports on and evaluates progress towards the implementation of recommendations it makes regarding biodiversity, how it identifies where activities have had impacts and uncovers the mechanisms through which they were successful, to provide an insight into how the Arctic Council can be an agent of change.

scholarly journals THE PATHOLOGIC EFFECTS OF STREPTOCOCCI FROM CASES OF POLIOMYELITIS AND OTHER SOURCES

1917 ◽  
Vol 25 (4) ◽  
pp. 557-580 ◽  
Author(s):  
Carroll G. Bull
Keyword(s):  
Spinal Cord ◽  
Guinea Pigs ◽  
The Other ◽  
Laboratory Animals ◽  
Histological Changes ◽  
Other Hand ◽  
Brain And Spinal Cord ◽  
The Brain

Streptococci cultivated from the tonsils of thirty-two cases of poliomyelitis were used to inoculate various laboratory animals. In no case was a condition induced resembling poliomyelitis clinically or pathologically in guinea pigs, dogs, cats, rabbits, or monkeys. On the other hand, a considerable percentage of the rabbits and a smaller percentage of some of the other animals developed lesions due to streptococci. These lesions consisted of meningitis, meningo-encephalitis, abscess of the brain, arthritis, tenosynovitis, myositis, abscess of the kidney, endocarditis, pericarditis, and neuritis. No distinction in the character or frequency of the lesions could be determined between the streptococci derived from poliomyelitic patients and from other sources. Streptococci isolated from the poliomyelitic brain and spinal cord of monkeys which succumbed to inoculation with the filtered virus failed to induce in monkeys any paralysis or the characteristic histological changes of poliomyelitis. These streptococci are regarded as secondary bacterial invaders of the nervous organs. Monkeys which have recovered from infection with streptococci derived from cases of poliomyelitis are not protected from infection with the filtered virus, and their blood does not neutralize the filtered virus in vitro. We have failed to detect any etiologic or pathologic relationship between streptococci and epidemic poliomyelitis in man or true experimental poliomyelitis in the monkey.

scholarly journals Us Mob Online: The Perils of Identifying as Indigenous on Social Media

Genealogy ◽  
2021 ◽  
Vol 5 (2) ◽  
pp. 52
Author(s):  
Bronwyn Carlson ◽  
Tristan Kennedy
Keyword(s):  
Social Media ◽  
Indigenous People ◽  
Indigenous Peoples ◽  
Mixed Methods Research ◽  
Indigenous Communities ◽  
Digital Environment ◽  
Collective Identities ◽  
Social Media Platforms ◽  
Insight Into

Social media is a highly valuable site for Indigenous people to express their identities and to engage with other Indigenous people, events, conversations, and debates. While the role of social media for Indigenous peoples is highly valued for public articulations of identity, it is not without peril. Drawing on the authors’ recent mixed-methods research in Australian Indigenous communities, this paper presents an insight into Indigenous peoples’ experiences of cultivating individual and collective identities on social media platforms. The findings suggest that Indigenous peoples are well aware of the intricacies of navigating a digital environment that exhibits persistent colonial attempts at the subjugation of Indigenous identities. We conclude that, while social media remains perilous, Indigenous people are harnessing online platforms for their own ends, for the reinforcement of selfhood, for identifying and being identified and, as a vehicle for humour and subversion.

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