scholarly journals Analysis of Experiences in Preventing COVID-19 in Hemodialysis Centers of the North of Poland before the Era of Vaccination

2022 ◽  
Vol 19 (2) ◽  
pp. 684
Author(s):  
Bogdan Biedunkiewicz ◽  
Leszek Tylicki ◽  
Ewelina Puchalska-Reglińska ◽  
Alicja Dębska-Ślizień
Keyword(s):  
Preventive Measures ◽  
Inverse Correlation ◽  
Survey Study ◽  
Medium Size ◽  
Additional Method ◽  
Significant Inverse Correlation ◽  
The North ◽  
Study Population ◽  
And Control ◽  
Preventive Methods

Background: The appearance of very contagious SARS-CoV-2 variants and waning vaccine immunity may indicate the need to return to using universal methods of preventing the spread of COVID-19. Methods: We performed a multicenter retrospective cohort survey study to describe the methods used in dialysis units to prevent and control the spread of SARS-CoV-2 and also the association between these methods and the incidence of COVID-19 among hemodialyzed (HD) patients before the era of vaccination. The study population included all maintenance HD patients (n = 1569) in 14 dialysis units in the Pomeranian Voivodeship. Results: The group of 352 patients (199 men, 153 female) were confirmed for COVID-19. The absolute cumulative incidence in the studied period was 22.4%. It varied widely by dialysis units, ranging from 9.4% to 36.9%. Universal preventive methods were applied by all units. Different additional methods were implemented in some stations with varying frequency (36–86%). In order to quantify the scale of the applied additional preventive methods, we calculated a summary prevention index (PI), i.e., one point for one additional method. Lower incidence was found in centers applying dialysis in isolation of patients hospitalized due to diseases requiring hospitalization (17.42% ± 6.89 vs. 26.54 ± 6.34; p = 0.028) and higher incidence in medium-size dialysis centers (ANOVA F: p = 0.017). Significant inverse correlation between PI and incidence was demonstrated as well (r = −0.759; p = 0.002). Conclusions: The higher the number of implemented preventive measures, the lower the risk of COVID-19 infection in HD patients. Among applied procedures the isolation of hospitalized patients is of significant importance. The measures proved to be effective in prevention before the vaccination era should be continued, as the threat of SARS-CoV-2 still exists.

scholarly journals COVID-19 outbreak and dental health care provision in Nigeria: a national survey

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Timothy Olukunle Aladelusi ◽  
Foluso Ayobami Atiba ◽  
Shakeerah Olaide Gbadebo ◽  
Yewande Isabella Adeyemo ◽  
Adeola Adenike Olusanya ◽  
...  
Keyword(s):  
Preventive Measures ◽  
Dental Health ◽  
Healthcare Providers ◽  
Dental Service ◽  
Surface Cleaning ◽  
Study Population ◽  
The Common ◽  
The Impact ◽  
Preventive Methods ◽  
Self Administered Questionnaire

Abstract Background The impact of the COVID-19 pandemic on the world is unprecedented, posing greater threats to vulnerable healthcare systems, especially in developing countries. This study aimed to assess the knowledge of dental healthcare providers in Nigeria about the disease and evaluate their responses to the preventive measures necessitated by COVID-19. Methods This was an online self-administered questionnaire-based study conducted among dentists practicing in Nigeria. A message containing the link to the survey was sent widely via social medial platforms and electronic mails to dentists practicing in Nigeria. The data collection was done between the 2nd of June and 3rd of July 2020. Results A total of 314 responses was recorded. Fever was the most specified generalized symptom (97.5%), while the use of masks (100%), hand hygiene (99.7%), social distancing (97.7%) and surface cleaning (99.4%) were the most commonly employed general preventive methods. The main identified risk of transmission in the clinic was aerosol generating procedures (98.7%). Conclusion The general knowledge of dental personnel in our study population appears to be adequate on the common clinical features of COVID-19 but less adequate regarding the less common features. The COVID-19 pandemic has also modified some aspects of dental service delivery but more needs to be done in this regard. Preventive measures against the transmission of COVID-19 in dental practice settings include proper utilization of teledentistry, clinical triage, preprocedural 1% hydrogen peroxide oral rinses, and the use of appropriate Personal Protective Equipment (PPE) which should always be encouraged.

High Levels of Plasma Protein C in Nephrotic Syndrome

1985 ◽  
Vol 53 (01) ◽  
pp. 005-007 ◽  
Author(s):  
I Pabinger-Fasching ◽  
K Lechner ◽  
H Niessner ◽  
P Schmidt ◽  
E Balzar ◽  
...  
Keyword(s):  
Nephrotic Syndrome ◽  
Plasma Protein ◽  
Protein C ◽  
Inverse Correlation ◽  
Elevated Plasma ◽  
Significant Inverse Correlation ◽  
At Iii ◽  
Thrombotic Tendency ◽  
Protein C Activity

SummaryIn patients with severe nephrotic syndrome determinations of plasma protein C : Ag levels (8 patients: 5 adults, 3 children) and protein C activity (3 out of 8 patients) revealed significantly elevated plasma protein C concentrations. Furthermore we observed a significant inverse correlation of protein C : Ag to AT III : Ag levels. No protein C : Ag could be detected in the urine of two patients studied. We conclude from our data, that changes of plasma protein C do not contribute to the high thrombotic tendency in nephrotic syndrome.

Efficacy of anthelmintic Eprimek against gastrointestinal nematodes in sheep

2020 ◽  
Vol 14 (4) ◽  
pp. 99-103
Author(s):  
V. I. Kolesnikov
Keyword(s):  
Live Weight ◽  
Gastrointestinal Nematodes ◽  
Production Environment ◽  
Control Groups ◽  
The North ◽  
Helminth Eggs ◽  
Nematode Eggs ◽  
Flotation Technique ◽  
And Control ◽  
Experimental Group

The purpose of the research is studying the efficacy of Eprimek (Eprinomectin) against gastrointestinal nematodes in sheep.Materials and methods. A commercial experiment to study the antiparasitic efficacy of Eprimek was carried out in June 2020 on 300 lambs of the North Caucasian breed in a private flock of Filimonovskaya Village, Izobilnensky District, the Stavropol Territory, which were divided into two groups. The experimental group of lambs (290 animals) was injected Eprimek subcutaneously at the earset at a dose of 1 ml/50 kg of live weight (10 mg of Eprinomectin in 1 ml), and 10 lambs were not treated; they were used as control. We collected feces from the lambs of the experimental and control groups before administration of the drugs and after 15 and 30 days. Fecal samples were examined by the flotation technique with a saturated solution of ammonium nitrate with counting nematode eggs in 1 g of feces. The results were processed statistically.Results and discussion. Eprimek showed a decrease in the number of excreted helminth eggs from 225.1±28.2 to 4.1±2.3 in production environment at a dose of 1 ml/50 kg of live weight, according to coprological studies on the 15th day after treatment in the experimental group of lambs. The efficacy was 98.2%, and 70% of the animals were free from the infection. The intensity of infection of the control lambs by gastrointestinal nematodes was 131–151 eggs per 1 g of feces at 100% prevalence.

The possible regulatory mechanisms of aqueous, ethyl acetate and nhexane fractions of the Ribes khorassanicum extract on acute hypertension in rats

2020 ◽  
Vol 20 ◽  
Author(s):  
Reza Mohebbati ◽  
Yasamin Kamkar-De ◽  
Mohammad Naser Shafei
Keyword(s):  
Ethyl Acetate ◽  
Antihypertensive Effect ◽  
Cardiovascular Responses ◽  
Regulatory Mechanisms ◽  
Hypertensive Rats ◽  
Control Groups ◽  
Acute Hypertension ◽  
The North ◽  
Significant Difference ◽  
And Control

Objective: Our previous studies showed the antihypertensive effect of Ribes khorassanicum (R. khorassanicum), a medicinal herb growing in the North Khorasan Province of Iran. For further evaluation, the present study investigated the effect of n-hexane (HX), ethyl acetate (EA), and aqueous (AQ) fractions of hydroalcoholic R. khorassanicum extract on cardiovascular responses in angiotensin II (AngII) and NG-nitro-L-arginine methyl ester (L-NAME) hypertensive rats. Methods: Wistar rats were randomly divided into 11 groups (n=5): 1) control, 2) AngII (50 ng/kg, i.v), 3) AngII + losartan (10 mg/kg, i.p), 4) L-NAME (10 mg/kg, i.v), 5) L-NAME+ sodium nitroprusside (SNP) (50 mg/kg, i.p), 6,7,8) one dose of each fraction of R. khorassanicum (AQ/EA/HX (50 mg/kg, i.p)) +AngII, and 9,10,11) one dose of each fraction of R. khorassanicum (AQ/EA/HX (50 mg/kg, i.p)) + L-NAME. Treated rats received three fractions 30 min before the injection of L-NAME and AngII in separate groups. The cardiovascular parameters were recorded by the Power Lab instrument via an angiocath inserted into the femoral artery. The peak changes (∆) of mean arterial pressure (MAP), systolic blood pressure (SBP), and heart rate (HR) in treated groups were compared with those of the hypertensive and control groups. Result: AngII and L-NAME significantly increased ∆MAP and ∆SBP and attenuated by pretreatment of LOS and SNP, respectively. Pretreatment with polar (AQ) and semipolar (EA) fractions of R. khorassanicum reduced the peak changes of MAP and SBP in both AngII and L-NAME-treated groups. Only the fraction of the herb attenuated the HR increased in the L-NAME group. The HR in other groups did not demonstrate any significant difference. Conclusion: All fractions of R. khorassanicum have an antihypertensive effect. However, the effect of polar fractions is more salient. It is also conceivable that the antihypertensive effect of fractions is mostly mediated by the inhibition of AngII.

scholarly journals Poult Enteritis and Mortality Syndrome in Turkey Poults: Causes, Diagnosis and Preventive Measures

Animals ◽  
2021 ◽  
Vol 11 (7) ◽  
pp. 2063
Author(s):  
Awad A. Shehata ◽  
Shereen Basiouni ◽  
Reinhard Sting ◽  
Valerij Akimkin ◽  
Marc Hoferer ◽  
...  
Keyword(s):  
Preventive Measures ◽  
Clinical Signs ◽  
Accurate Diagnosis ◽  
Economic Losses ◽  
Turkey Poults ◽  
Causative Agents ◽  
Enteric Disorders ◽  
And Control ◽  
Enteropathogenic Viruses ◽  
Poult Enteritis

Poult enteritis and mortality syndrome (PEMS) is one of the most significant problem affecting turkeys and continues to cause severe economic losses worldwide. Although the specific causes of PEMS remains unknown, this syndrome might involve an interaction between several causative agents such as enteropathogenic viruses (coronaviruses, rotavirus, astroviruses and adenoviruses) and bacteria and protozoa. Non-infectious causes such as feed and management are also interconnected factors. However, it is difficult to determine the specific cause of enteric disorders under field conditions. Additionally, similarities of clinical signs and lesions hamper the accurate diagnosis. The purpose of the present review is to discuss in detail the main viral possible causative agents of PEMS and challenges in diagnosis and control.

scholarly journals The Dependence of Renal 68Ga[Ga]-DOTATOC Uptake on Kidney Function and Its Relevance for Peptide Receptor Radionuclide Therapy with 177Lu[Lu]-DOTATOC

Diagnostics ◽  
2021 ◽  
Vol 11 (7) ◽  
pp. 1216
Author(s):  
Falk Gühne ◽  
Alexander Heinzig ◽  
Philipp Seifert ◽  
Robert Drescher ◽  
Martin Freesmeyer
Keyword(s):  
Kidney Function ◽  
Specific Binding ◽  
Correlation Coefficients ◽  
Inverse Correlation ◽  
Peptide Receptor Radionuclide Therapy ◽  
Tracer Uptake ◽  
Significant Inverse Correlation ◽  
Peptide Receptor ◽  
Pet Ct ◽  
Induced Changes

Background: In addition to its SSTR-specific binding in tumors and healthy tissues, DOTATOC analogues accumulate in kidney parenchyma. Renal tracer uptake might be a surrogate of kidney function or dysfunction. This study aimed to evaluate if kidney function can be estimated from 68Ga[Ga]-DOTATOC uptake in PET/CT and its impact on the nephrotoxicity of 177Lu[Lu]-DOTATOC PRRT. Methods: Two cohorts of patients (A: 128 diagnostic patients; B: 32 PRRT patients) were evaluated retrospectively. SUV values of the kidneys, physiologically SSTR-expressing organs and in background compartments were assessed. Kidney function was calculated as eGFR by CKD-EPI creatinine equation. Pearson’s correlation coefficients and treatment-induced changes of uptake and kidney function were assessed and compared. Results: Kidney function and renal DOTATOC uptake showed a significant inverse correlation (R2 = 0.037; p = 0.029). Evaluated models of PET/CT measurements were not able to predict kidney function sufficiently. The uptake of other organs did not depend on eGFR. While the renal uptake increased after PRRT (p < 0.001), the kidney function did not change significantly (p = 0.382). Neither low pre-therapeutic eGFR nor high pre-therapeutic kidney uptake were risk factors of PRRT-induced deterioration in kidney function. Conclusion: The relevance of kidney function for renal 68Ga[Ga]-DOTATOC uptake is limited. The nephrotoxicity of 177Lu[Lu]-DOTATOC PRRT might be low and cannot be reliably predicted by pre-therapeutic measurements.

Construct Validity for Self-Acceptance and Fear of Negative Evaluation

2001 ◽  
Vol 89 (2) ◽  
pp. 386-386 ◽  
Author(s):  
Mark W. Durm ◽  
Patricia E. Glaze
Keyword(s):  
Construct Validity ◽  
Inverse Correlation ◽  
The Self ◽  
Negative Evaluation ◽  
Fear Of Negative Evaluation ◽  
Significant Inverse Correlation ◽  
Acceptance Scale ◽  
Self Acceptance

For 55 students (13 men, 42 women) there was a significant inverse correlation for scores on the Self-acceptance Scale and scores on the Fear of Negative Evaluation Scale, thereby giving credence to the construct validity of both scales, that is, the more one accepts oneself, the less negative evaluation there is of oneself.

ENDOTHELIAL FUNCTION IN CHILDREN WITH PERIODONTITIS

2021 ◽  
pp. 154-161
Author(s):  
Agapitov L.I. ◽  
Cherepnina I.V.
Keyword(s):  
Cardiovascular Diseases ◽  
Endothelial Dysfunction ◽  
Chronic Periodontitis ◽  
Preventive Measures ◽  
Inverse Correlation ◽  
Healthy Children ◽  
Flow Mediated Dilatation ◽  
Vascular Dilatation ◽  
Oral Inflammation

The presence of oral inflammation has recently been linked with the pathogenesis of cardiovascular diseases. Endothelial dysfunction is considered one of the pathogenetic mechanisms of a whole range of cardiovascular diseases. In the study describes links between periodontitis and endothelial dysfunction. 32 patients (16 boys and 16 girls) with periodontitis and 60 healthy children were examined. Flow-mediated vascular dilatation data were measured in all patients. Flow-mediated dilatation was 9,78±3,16% in children with periodontitis, and 12,85±3,48% in healthy children (p<0,05). Area under the dilation curve was larger in healthy children, then in children with periodontitis, 710±121%·с in comparison with 519±175%·с (p<0,05). An inverse correlation was found between flow-mediated dilatation, area under the dilation curve and periodontitis duration (r = -0,71, -0,77). A negative correlation was found between flow-mediated dilatation, area under the dilation curve and worsening of periodontitis (r = -0,70, -0,71). This study did not demonstrate association between periodontal disease in children and arterial hypertension, coronary heart disease, heart failure. However, the identified endothelial dysfunction requires protective therapeutic and preventive measures. Given the insignificant symptoms of chronic periodontitis in the examined children, it is important to activate efforts aimed at early detection and treatment of this disease. Further research is needed to clarify the prognostic role of endothelial dysfunction in chronic periodontitis.

Loon abundance and behaviour over four decades at a remote ecological reserve on Haida Gwaii, British Columbia, Canada

2021 ◽  
Vol 135 (1) ◽  
pp. 28-38
Author(s):  
Thomas Reimchen ◽  
Sheila Douglas
Keyword(s):  
British Columbia ◽  
Gasterosteus Aculeatus ◽  
Evolutionary Ecology ◽  
Inverse Correlation ◽  
Gavia Immer ◽  
Haida Gwaii ◽  
Average Wind Speed ◽  
The North ◽  
Common Loons ◽  
Ecological Reserve

Early studies (1976–1982) of the Drizzle Lake Ecological Reserve on Haida Gwaii, British Columbia focussed on the endemic Giant Threespine Stickleback (Gasterosteus aculeatus) and their predators. These surveys showed daily visits to the small lake (110 ha) by up to 59 adult non-breeding Common Loon (Gavia immer), an important stickleback predator and up to 19 breeding and non-breeding adult Red-throated Loon (Gavia stellata), which leave daily to forage in nearby marine waters. We continued loon surveys for 17 additional years (1983–1989, 2011–2020) and found that aggregations of non-breeding Common Loons occurred annually on the lake during July with maximum daily numbers of 78–83 individuals in 1987, 2018, and 2020 and a large increase from 2011 to 2020. We did not detect any relationship of these differences with the Pacific Decadal Oscillation but a significant inverse correlation with average wind speed. Average yearly numbers of Red-throated Loons declined by 50% from 1976 to 1989 and have remained low, with lowest numbers (<2) occurring in 2017. Two Red-throated Loon nesting territories on the lake were occupied from 1976 to 1995, with chicks occurring in 24 of 36 nests, but no successful nesting was observed on the lake over the last decade. The relative decline of Red-throated Loon in this reserve is similar to that reported in Arctic and Subarctic surveys of the species in the north Pacific and northern Europe. We discuss the implications for the evolutionary ecology of the sticklebacks and the conservation of the ecological reserve.

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