How Exercise and Dietary Intervention Affect the Outcome of Osteosarcopenic Obesity Syndrome?

Osteosarcopenic obesity (OSO) is described by the simultaneous presence of osteopenia/osteoporosis, sarcopenia, and increased adiposity. Over time, older adults with OSO syndrome might be at greater risk for loss of physical function and bone fractures. Furthermore, a sedentary lifestyle, inadequate nutrition, pharmaceutical drugs and chronic conditions encompass the multifactorial nature of OSO syndrome. Physical activity and a healthy diet play a crucial role in management and treatment of OSO syndrome. Research has shown that even low-intensity physical activity or daily habitual activity can maintain bone mineral density, muscle strength and improve muscle quality, and reduce adiposity. However, older adults with high risk of fall and injuries require tailored exercise intensity. Also, balanced daily intake of vitamin D, calcium and protein is important in prevention and treatment of OSO syndrome in postmenopausal women. Effective measurement of bone mass, muscle mass and strength is required when detecting OSO syndrome and to evaluate the balance, strength and endurance of elder individuals and severity of the condition.

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Another Impairment in Older Age: What Does Osteosarcopenic Obesity Syndrome Mean for Middle-Aged and Older Women?

Journal of the American Medical Directors Association ◽

10.1016/j.jamda.2017.05.001 ◽

2017 ◽

Vol 18 (8) ◽

pp. 648-650 ◽

Cited By ~ 7

Author(s):

Jasminka Z. Ilich

Keyword(s):

Older Women ◽

Older Age ◽

Middle Aged ◽

Osteosarcopenic Obesity ◽

Obesity Syndrome

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How common is osteosarcopenic obesity syndrome (OSO) in an adult population?

http://isrctn.com/ ◽

10.1186/isrctn13557768 ◽

2021 ◽

Author(s):

Atle Saeterbakken

Keyword(s):

Adult Population ◽

Osteosarcopenic Obesity ◽

Obesity Syndrome

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288: The Men's Eating and Living (Meal) Study: A Multi-Center Pilot Trial of Dietary Intervention for the Treatment of Prostate Cancer

The Journal of Urology ◽

10.1016/s0022-5347(18)30553-6 ◽

2007 ◽

Vol 177 (4S) ◽

pp. 96-97

Author(s):

J. Kellogg Parsons ◽

Vicky Newman ◽

James L. Mohler ◽

John P. Pierce ◽

Electra Paskett ◽

...

Keyword(s):

Prostate Cancer ◽

Dietary Intervention ◽

Pilot Trial ◽

Meal Study

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Responses to Two Weight-loss Programs Based on Approximating the Diet to the Ideal: Differences Associated with Increased Cereal or Vegetable Consumption

International Journal for Vitamin and Nutrition Research ◽

10.1024/0300-9831.76.6.367 ◽

2006 ◽

Vol 76 (6) ◽

pp. 367-376 ◽

Cited By ~ 9

Author(s):

Ortega ◽

Rodríguez-Rodríguez ◽

Aparicio ◽

Marín-Arias ◽

López-Sobaler

Keyword(s):

Weight Loss ◽

Weight Control ◽

Dietary Intervention ◽

Vegetable Consumption ◽

Healthy Eating Index ◽

Anthropometric Data ◽

Control Programs ◽

Weight Loss Programs ◽

Spanish Women ◽

The Ideal

The fight against excess weight and obesity is a health priority. The aim of this study was to analyze the anthropometric changes induced by two weight control programs based on approximating the diet to the theoretical ideal (increasing the consumption of foods with the largest differences between the recommended and observed intakes: cereals and vegetables – for which a minimum of 6 and 3 servings/day are recommended, respectively). The study subjects were 57 Spanish women with a body-mass index (BMI) of 24–35 kg/m², all of whom were randomly assigned to one of two slightly hypocaloric diets for a six-week period: diet V, in which the consumption of greens and vegetables was increased, or diet C, in which the consumption of cereals was increased. Dietetic and anthropometric data were collected at the start of the study and again at two and six weeks. The dietary intervention approximated the subjects’ energy provision from proteins, fats, and carbohydrates to those recommended. The Healthy Eating Index (HEI) improved with both diets. Reductions in body weight, BMI, and the amount of body fat (kg) were also achieved with both diets. Weight loss was 1.56 ± 0.93 kg and 1.02 ± 0.55 kg at two weeks with diet C and V respectively, and 2.8 ± 1.4 kg and 2.0 ± 1.3 kg at six weeks (p < 0.05). Approximating the diet to the theoretical ideal by increasing the consumption of vegetables or cereals may therefore be of use in weight control. In terms of weight loss and the improvement of the diet quality (energy profile and HEI), diet C was significantly more effective than diet V.

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The Role of Polyphenols in the Modulation of Plasma Non-Enzymatic Antioxidant Capacity (NEAC)

International Journal for Vitamin and Nutrition Research ◽

10.1024/0300-9831/a000116 ◽

2012 ◽

Vol 82 (3) ◽

pp. 228-232 ◽

Cited By ~ 7

Author(s):

Mauro Serafini ◽

Giuseppa Morabito

Keyword(s):

Antioxidant Capacity ◽

Dietary Intervention ◽

Ex Vivo ◽

The Body ◽

Dietary Polyphenols ◽

Enzymatic Antioxidant ◽

Endogenous Antioxidant

Dietary polyphenols have been shown to scavenge free radicals, modulating cellular redox transcription factors in different in vitro and ex vivo models. Dietary intervention studies have shown that consumption of plant foods modulates plasma Non-Enzymatic Antioxidant Capacity (NEAC), a biomarker of the endogenous antioxidant network, in human subjects. However, the identification of the molecules responsible for this effect are yet to be obtained and evidences of an antioxidant in vivo action of polyphenols are conflicting. There is a clear discrepancy between polyphenols (PP) concentration in body fluids and the extent of increase of plasma NEAC. The low degree of absorption and the extensive metabolism of PP within the body have raised questions about their contribution to the endogenous antioxidant network. This work will discuss the role of polyphenols from galenic preparation, food extracts, and selected dietary sources as modulators of plasma NEAC in humans.

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Protective effects of soy-isoflavones in cardiovascular disease

Hämostaseologie ◽

10.1055/s-0037-1616927 ◽

2008 ◽

Vol 28 (01/02) ◽

pp. 85-88 ◽

Cited By ~ 16

Author(s):

D. Fuchs ◽

H. Daniel ◽

U. Wenzel

Keyword(s):

Cardiovascular Disease ◽

Endothelial Cells ◽

Molecular Mechanisms ◽

Dietary Intervention ◽

Mononuclear Cells ◽

Oxidized Ldl ◽

Proteome Analysis ◽

Soy Isoflavones ◽

Protective Effects ◽

Estrogen Production

SummaryEpidemiological studies indicate that the consumption of soy-containing food may prevent or slow-down the development of cardiovascular disease. In endothelial cells application of a soy extract or a combination of the most abundant soy isoflavones genistein and daidzein both inhibited apoptosis, a driving force in atherosclerosis development, when applied in combination with oxidized LDL or homocysteine. Proteome analysis revealed that the stressorinduced alteration of protein expression profile was reversed by the soy extract or the genistein/daidzein mixture. Only few protein entities that could be functionally linked to mitochondrial dysfunction were regulated in common by both application forms of isoflavones. A dietary intervention with isoflavone-enriched soy extract in postmenopausal women, who generally show strongly increased cardiovascular risk due to diminished estrogen production, led to significant alterations in the steady state levels of proteins from mononuclear blood cells. The proteins identified by proteome analysis revealed that soy isoflavones may increase the anti-inflammatory response in blood mononuclear cells thereby contributing to the atherosclerosispreventive activities of a soy-rich diet. Conclusion: By proteome analysis protein targets were identified in vitro in endothelial cells that respond to soy isoflavones and that may decipher molecular mechanisms through which soy products exert their protective effects in the vasculature.

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