Compilation and Analysis of Web-Based Orthopedic Personalized Predictive Tools: A Scoping Review

Web-based personalized predictive tools in orthopedic surgery are becoming more widely available. Despite rising numbers of these tools, many orthopedic surgeons may not know what tools are available, how these tools were developed, and how they can be utilized. The aim of this scoping review is to compile and synthesize the profile of existing web-based orthopedic tools. We conducted two separate PubMed searches—one a broad search and the second a more targeted one involving high impact journals—with the aim of comprehensively identifying all existing tools. These articles were then screened for functional tool URLs, methods regarding the tool’s creation, and general inputs and outputs required for the tool to function. We identified 57 articles, which yielded 31 unique web-based tools. These tools involved various orthopedic conditions (e.g., fractures, osteoarthritis, musculoskeletal neoplasias); interventions (e.g., fracture fixation, total joint arthroplasty); outcomes (e.g., mortality, clinical outcomes). This scoping review highlights the availability and utility of a vast array of web-based personalized predictive tools for orthopedic surgeons. Increased awareness and access to these tools may allow for better decision support, surgical planning, post-operative expectation management, and improved shared decision-making.

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Improving Management of Osteoarthritis: Patients’ Perceptions of a Surgical Readiness Interview Tool

Journal of Family Medicine ◽

10.26420/jfammed.2021.1268 ◽

2021 ◽

Vol 8 (7) ◽

Author(s):

Barton KI ◽

◽

Hewison CE ◽

Kania-Richmond A ◽

◽

...

Keyword(s):

Qualitative Interviews ◽

Comparison Method ◽

Joint Arthroplasty ◽

Modifiable Risk Factors ◽

Management Process ◽

Care Provision ◽

Patient Orientation ◽

Convenience Sample ◽

Orthopedic Surgeons ◽

Expectation Management

Almost half of patients referred to orthopedic surgeons for Total Joint Arthroplasty (TJA) do not require TJA at that time or are not appropriate surgical candidates. The objective was to explore patients’ perspectives of a Surgical Readiness Interview Tool and its potential utility in the Osteoarthritis (OA) management process. Semi-structured qualitative interviews were conducted with a convenience sample of patients from arthroplasty clinics in Alberta. All interviews were digitally recorded and transcribed verbatim. Analysis was conducted iteratively, applying a constant comparison method. Nine patients were interviewed. Participants found the interview tool to be relevant and comprehensible. Suggestions were made on how to improve tool clarity and administration processes. Patient orientation versus that of the doctor, and expectation management emerged as salient factors in the meaningful application of the tool. As a result of the interviews, a revised tool was developed which incorporated the participant suggestions. Patients were positive about the interview tool and felt that it would lead to better care provision, particularly with incorporation of participants’ suggestions. The data suggest that the interview tool could improve the conversation on surgical readiness, conservative management, and addressing modifiable risk factors prior to TJA.

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Survey of Similarity-Based Prediction of Drug-Protein Interactions

Current Medicinal Chemistry ◽

10.2174/0929867326666190808154841 ◽

2020 ◽

Vol 27 (35) ◽

pp. 5856-5886 ◽

Cited By ~ 4

Author(s):

Chen Wang ◽

Lukasz Kurgan

Keyword(s):

Computational Methods ◽

Protein Interactions ◽

Future Development ◽

High Impact ◽

Therapeutic Protein ◽

Knowledge Gap ◽

Therapeutic Activity ◽

Drug Molecule ◽

Protein Targets ◽

Predictive Tools

Therapeutic activity of a significant majority of drugs is determined by their interactions with proteins. Databases of drug-protein interactions (DPIs) primarily focus on the therapeutic protein targets while the knowledge of the off-targets is fragmented and partial. One way to bridge this knowledge gap is to employ computational methods to predict protein targets for a given drug molecule, or interacting drugs for given protein targets. We survey a comprehensive set of 35 methods that were published in high-impact venues and that predict DPIs based on similarity between drugs and similarity between protein targets. We analyze the internal databases of known PDIs that these methods utilize to compute similarities, and investigate how they are linked to the 12 publicly available source databases. We discuss contents, impact and relationships between these internal and source databases, and well as the timeline of their releases and publications. The 35 predictors exploit and often combine three types of similarities that consider drug structures, drug profiles, and target sequences. We review the predictive architectures of these methods, their impact, and we explain how their internal DPIs databases are linked to the source databases. We also include a detailed timeline of the development of these predictors and discuss the underlying limitations of the current resources and predictive tools. Finally, we provide several recommendations concerning the future development of the related databases and methods.

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Development of an electronic conversation aid to support shared decision making for children with acute otitis media

JAMIA Open ◽

10.1093/jamiaopen/ooab024 ◽

2021 ◽

Vol 4 (2) ◽

Author(s):

Jana L Anderson ◽

e Silva Lucas Oliveira J ◽

Juan P Brito ◽

Ian G Hargraves ◽

Erik P Hess

Keyword(s):

Decision Making ◽

Shared Decision Making ◽

Otitis Media ◽

Acute Otitis Media ◽

Medical Knowledge ◽

Complication Rates ◽

Shared Decision ◽

Web Based ◽

Quality Issue ◽

The Impact

Abstract Objective The overuse of antibiotics for acute otitis media (AOM) in children is a healthcare quality issue in part arising from conflicting parent and physician understanding of the risks and benefits of antibiotics for AOM. Our objective was to develop a conversation aid that supports shared decision making (SDM) with parents of children who are diagnosed with non-severe AOM in the acute care setting. Materials and Methods We developed a web-based encounter tool following a human-centered design approach that includes active collaboration with parents, clinicians, and designers using literature review, observations of clinical encounters, parental and clinician surveys, and interviews. Insights from these processes informed the iterative creation of prototypes that were reviewed and field-tested in patient encounters. Results The ear pain conversation aid includes five sections: (1) A home page that opens the discussion on the etiologies of AOM; (2) the various options available for AOM management; (3) a pictograph of the impact of antibiotic therapy on pain control; (4) a pictograph of complication rates with and without antibiotics; and (5) a summary page on management choices. This open-access, web-based tool is located at www.earpaindecisionaid.org. Conclusions We collaboratively developed an evidence-based conversation aid to facilitate SDM for AOM. This decision aid has the potential to improve parental medical knowledge of AOM, physician/parent communication, and possibly decrease the overuse of antibiotics for this condition.

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Current Status and Future Prospects for Shared Decision Making before and after Total Knee Replacement Surgery—A Scoping Review

International Journal of Environmental Research and Public Health ◽

10.3390/ijerph18020668 ◽

2021 ◽

Vol 18 (2) ◽

pp. 668

Author(s):

Geert van der Sluis ◽

Jelmer Jager ◽

Ilona Punt ◽

Alexandra Goldbohm ◽

Marjan J. Meinders ◽

...

Keyword(s):

Decision Making ◽

Decision Support ◽

Total Knee Replacement ◽

Shared Decision Making ◽

Knee Replacement ◽

Study Design ◽

Scoping Review ◽

Decision Aids ◽

Shared Decision ◽

Total Knee

Background. To gain insight into the current state-of-the-art of shared decision making (SDM) during decisions related to pre and postoperative care process regarding primary total knee replacement (TKR). Methods. A scoping review was performed to synthesize existing scientific research regarding (1) decisional needs and preferences of patients preparing for, undergoing and recovering from TKR surgery, (2) the relation between TKR decision-support interventions and SDM elements (i.e., team talk, option talk, and decision talk), (3) the extent to which TKR decision-support interventions address patients’ decisional needs and preferences. Results. 2526 articles were identified, of which 17 articles met the inclusion criteria. Of the 17 articles, ten had a qualitative study design and seven had a quantitative study design. All included articles focused on the decision whether to undergo TKR surgery or not. Ten articles (all qualitative) examined patients’ decisional needs and preferences. From these, we identified four domains that affected the patients’ decision to undergo TKR: (1) personal factors, (2) external factors, (3) information sources and (4) preferences towards outcome prediction. Seven studies (5) randomized controlled trials and 2 cohort studies) used quantitative analyses to probe the effect of decision aids on SDM and/or clinical outcomes. In general, existing decision aids did not appear to be tailored to patient needs and preferences, nor were the principles of SDM well-articulated in the design of decision aids. Conclusions. SDM in TKR care is understudied; existing research appears to be narrow in scope with limited relevance to established SDM principles and the decisional needs of patients undertaking TKR surgery.

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Ketogenic Dietary Therapies in Patients with Autism Spectrum Disorder: Facts or Fads? A Scoping Review and a Proposal for a Shared Protocol

Nutrients ◽

10.3390/nu13062057 ◽

2021 ◽

Vol 13 (6) ◽

pp. 2057

Author(s):

Costanza Varesio ◽

Serena Grumi ◽

Martina Paola Zanaboni ◽

Martina Maria Mensi ◽

Matteo Chiappedi ◽

...

Keyword(s):

Autism Spectrum Disorder ◽

Scoping Review ◽

Pediatric Patients ◽

Neurodevelopmental Disorder ◽

Autism Spectrum ◽

Spectrum Disorder ◽

Dietary Interventions ◽

Web Based ◽

Potential Efficacy ◽

Study Designs

Autism spectrum disorder (ASD) is a neurodevelopmental disorder with increasing incidence. An expanding body of literature is examining connections between ASD and dietary interventions. Existing reports suggest a beneficial effect of ketogenic dietary therapies (KDTs) in improving behavioral symptoms in ASD. In this context, the purpose of this scoping review was to identify and map available evidence in the literature about the feasibility and potential efficacy of KDTs in pediatric patients with ASD and to inform clinical practice in the field. Moreover, based on the resulting data from the literature review, we aimed to provide a shared protocol to develop a personalized KDT intervention in patients with ASD. A comprehensive and structured web-based literature search was performed using PubMed and Scopus and it yielded 203 records. Seven papers were finally selected and included in the review. Data were abstracted by independent coders. High variability was identified in study designs and dietary aspects emerged among selected studies. Results supported the effectiveness of KDTs in promoting behavioral improvements. Clinical recommendations on which patients may benefit most from KDTs implementation and difficulties in dietary adherence were discussed.

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MORE WORK NEEDED ON DECISION ANALYSIS FOR SHARED DECISION-MAKING: A SCOPING REVIEW

Journal of Clinical Epidemiology ◽

10.1016/j.jclinepi.2021.10.001 ◽

2021 ◽

Author(s):

Brittany Humphries ◽

Montserrat León-García ◽

Ena Niño de Guzman Quispe ◽

Carlos Canelo-Aybar ◽

Claudia Valli ◽

...

Keyword(s):

Decision Making ◽

Decision Analysis ◽

Shared Decision Making ◽

Scoping Review ◽

Shared Decision

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Military Orthopedic Surgeons Are Not Just Traumatologists

Military Medicine ◽

10.1093/milmed/usab400 ◽

2021 ◽

Author(s):

Camille Choufani ◽

Olivier Barbier ◽

Laurent Mathieu ◽

Nicolas de L’Escalopier

Keyword(s):

Orthopedic Surgery ◽

Descriptive Analysis ◽

Trauma Surgery ◽

Armed Forces ◽

Trauma Surgeon ◽

Reconstruction Surgery ◽

Orthopedic Surgeon ◽

Orthopedic Surgeons ◽

French Military ◽

Military Patients

ABSTRACT Introduction Each French military orthopedic surgeon is both an orthopedic surgeon and a trauma surgeon. Their mission is to support the armed forces in France and on deployment. The aim of this study was to describe the type of orthopedic surgery performed for the armed forces in France. Our hypothesis was that scheduled surgery was more common than trauma surgery. Methods We conducted a retrospective descriptive analysis of the surgical activity for military patients in the orthopedic surgery departments of the four French military platform hospitals. All surgical procedures performed during 2020 were collected. We divided the procedures into the following categories: heavy and light trauma, posttraumatic reconstruction surgery, sports surgery, degenerative surgery, and specialized surgery. Our primary endpoint was the number of procedures performed per category. Results A total of 827 individuals underwent surgery, 91 of whom (11%) were medical returnees from deployment. The surgeries performed for the remaining 736 soldiers present in metropolitan France (89%) consisted of 181 (24.6%) trauma procedures (of which 86.7% were light trauma) and 555 (75.4%) scheduled surgery procedures (of which 60.8% were sports surgery). Among the medical returnees, there were 71 traumatology procedures (78%, of which 87.3% were light traumatology) and 20 procedures corresponding to surgery usually carried out on a scheduled basis (22%, of which 95% were sports surgery). Conclusion Military orthopedic surgeons are not just traumatologists; their activity for the armed forces is varied and mainly consists of so-called programmed interventions.

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Patient engagement, treatment preferences and shared decision-making in the treatment of opioid use disorder in adults: a scoping review protocol

BMJ Open ◽

10.1136/bmjopen-2018-022267 ◽

2018 ◽

Vol 8 (10) ◽

pp. e022267 ◽

Cited By ~ 2

Author(s):

Tyler Marshall ◽

Elizabeth N Kinnard ◽

Myles Hancock ◽

Susanne King-Jones ◽

Karin Olson ◽

...

Keyword(s):

Decision Making ◽

Shared Decision Making ◽

Scoping Review ◽

Search Strategy ◽

Opioid Use Disorder ◽

Treatment Preferences ◽

Shared Decision ◽

Opioid Use ◽

Policy Makers ◽

Cochrane Database

IntroductionOpioid use disorder (OUD) is characterised by the fifth Edition of the Diagnostic and Statistics Manual as a problematic pattern of opioid use (eg, fentanyl, heroin, oxycodone) that leads to clinically significant impairment. OUD diagnoses have risen substantially over the last decade, and treatment services have struggled to meet the demand. Evidence suggests when patients with chronic illnesses are matched with their treatment preferences and engaged in shared decision-making (SDM), health outcomes may improve. However, it is not known whether SDM could impact outcomes in specific substance use disorders such as OUD.Methods and analysisA scoping review will be conducted according to Arksey and O’Malley’s framework and by recommendations from Levacet al. The search strategy was developed to retrieve relevant publications from database inception and June 2017. MEDLINE, EMBASE, PsycINFO, Cochrane Database for Controlled Trials, Cochrane Database for Systematic Reviews and reference lists of relevant articles and Google Scholar will be searched. Included studies must be composed of adults with a diagnosis of OUD, and investigate SDM or its constituent components. Experimental, quasi-experimental, qualitative, case–control, cohort studies and cross-sectional surveys will be included. Articles will be screened for final eligibility according to title and abstract, and then by full text. Two independent reviewers will screen excluded articles at each stage. A consultation phase with expert clinicians and policy-makers will be added to set the scope of the work, refine research questions, review the search strategy and identify additional relevant literature. Results will summarise whether SDM impacts health and patient-centred outcomes in OUD.Ethics and disseminationScoping review methodology is considered secondary analysis and does not require ethics approval. The final review will be submitted to a peer-reviewed journal, disseminated at relevant academic conferences and will be shared with policy-makers, patients and clinicians.

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Multidisciplinary teams caring for people with variations of sex characteristics: a scoping review

BMJ Paediatrics Open ◽

10.1136/bmjpo-2021-001257 ◽

2021 ◽

Vol 5 (1) ◽

pp. e001257

Author(s):

Martin Gramc ◽

Jürg Streuli ◽

Eva de Clercq

Keyword(s):

Decision Making ◽

Shared Decision Making ◽

Scoping Review ◽

Ethical Principles ◽

Care Process ◽

Future Research ◽

Medical Professionals ◽

Sex Characteristics ◽

Multidisciplinary Teams ◽

Shared Decision

BackgroundIn 2006 the Chicago consensus statement on the management of people with variations of sex characteristics (VSC) acknowledged the importance of a multidisciplinary team (MDT) approach. The consensus update from 2016 reinforced the call for multidisciplinary collaborations between medical professionals, parents and support groups, and proposed guidelines to improve shared decision making and patient-centred care embedded in ethical principles of self-determination and child participation. But there is little evidence that successfully MDTs have been implemented in clinical practice.Methods and aimsA scoping review was conducted to identify studies that address the collaboration and decision making process of MDTs providing care of people with VSC to identify ideal and actual (1) team composition; (2) models of collaboration and (3) ethical principles that MDTs follow. Six databases were systematically searched: CINAHIL, Medline, Psychinfo, Scopus, Socindex and Web of Science. No restriction was placed on the type of methodology used in the studies. To frame the research, the Preferred Reporting Items for Systematic Reviews and Meta-Analyses was used.ResultsThe MDTs in the literature include mainly medical professionals: endocrinologists, urologists and surgeons. The collaboration among medical professionals in MDTs lacks cooperation as one team member sets the tasks of the team while each professional works separately. Despite the importance of psycho-social support the involvement of psychologists remains secondary. The implementation of ethical principles tends to exclude people with VSC.ConclusionThe care of people with VSC described in the papers is medically oriented as the team members are mainly medical professionals working separately. MDT tend to exclude people with VSC despite references to shared decision making processes and informed consent. There was no mention of adult care and lack of inclusion of patient’s perspective in the care process. The future research should do more empirical research of MDTs.

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Penerapan Metode SCRUM dalam Pengembangan Sistem Informasi Layanan Kawasan

Jurnal Teknik Informatika dan Sistem Informasi ◽

10.28932/jutisi.v6i2.2711 ◽

2020 ◽

Vol 6 (2) ◽

Author(s):

Warkim Warkim ◽

Muhamad Hanif Muslim ◽

Farham Harvianto ◽

Setiawan Utama

Keyword(s):

Information System ◽

Business Processes ◽

High Impact ◽

Organizational Changes ◽

Web Based ◽

Research Institution ◽

Service Information ◽

Regional Service ◽

World Class ◽

Work Units

The development of technology is very influential in the business processes of an organization to be able to carry out its duties and functions. As a government agency engaged in research, the Indonesian Institute of Sciences (LIPI) needs to make organizational changes to support its vision as a world-class research institution. One of the first steps taken is reorganizing and redistributing employees that have a high impact on the business process of service to employees because the supporting resources are placed corporately and no longer in the work units. To deal with this problem, we developed a Regional Service Information System using the Scrum methodology. The output is a web-based software that facilitates service requests needed by employees, ranging from service submission, processing by the Area Manager and Central Manager, to being received again by the service requester. The Regional Service Information System is expected to be a solution to the problems that arise as a result of the redistribution of employees at LIPI and to improve the effectiveness of employees as the research supporting resources.

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