scholarly journals Applying Seaweed Compounds in Cosmetics, Cosmeceuticals and Nutricosmetics

Marine Drugs ◽  
2021 ◽  
Vol 19 (10) ◽  
pp. 552
Author(s):  
Lucía López-Hortas ◽  
Noelia Flórez-Fernández ◽  
Maria D. Torres ◽  
Tania Ferreira-Anta ◽  
María P. Casas ◽  
...  
Keyword(s):  
Bioactive Compounds ◽  
Algal Blooms ◽  
Low Cost ◽  
Wide Distribution ◽  
Biological Properties ◽  
Waste Streams ◽  
Patent Literature ◽  
Renewable Material ◽  
Technical Features ◽  
Skin Care Products

The interest in seaweeds for cosmetic, cosmeceutics, and nutricosmetics is increasing based on the demand for natural ingredients. Seaweeds offer advantages in relation to their renewable character, wide distribution, and the richness and versatility of their valuable bioactive compounds, which can be used as ingredients, as additives, and as active agents in the formulation of skin care products. Bioactive compounds, such as polyphenols, polysaccharides, proteins, peptides, amino acids, lipids, vitamins, and minerals, are responsible for the biological properties associated with seaweeds. Seaweed fractions can also offer technical features, such as thickening, gelling, emulsifying, texturizing, or moistening to develop cohesive matrices. Furthermore, the possibility of valorizing industrial waste streams and algal blooms makes them an attractive, low cost, raw and renewable material. This review presents an updated summary of the activities of different seaweed compounds and fractions based on scientific and patent literature.

Natural Bioactive Compounds As Adjuvant Therapy For Hepatitis C Infection

2020 ◽  
Vol 16 ◽  
Author(s):  
Moema S. Santana ◽  
Rute Lopes ◽  
Isabela H. Peron ◽  
Carla R. Cruz ◽  
Ana M. M. Gaspar ◽  
...  
Keyword(s):  
Hepatitis C ◽  
Bioactive Compounds ◽  
Low Cost ◽  
Chemical Diversity ◽  
Acute Hepatitis C ◽  
Hepatitis C Infection ◽  
Middle Income ◽  
Broad Perspective ◽  
Cost Of Production

Background: Hepatitis C virus infection is a significant global health burden, which causes acute or chronic hepatitis. The acute hepatitis C is generally asymptomatic and progresses to cure, while persistent infection can progress to chronic liver disease and extrahepatic manifestations. Standard treatment is expensive, poorly tolerated, and has variable sustained virologic responses amongst the different viral genotypes. New therapies involve direct acting antivirals; however, it is also very expensive and may not be accessible for all patients worldwide. In order to provide a complementary approach to the already existing therapies, natural bioactive compounds are investigated as to their several biologic activities, such as direct antiviral properties against hepatitis C, and effects on mitigating chronic progression of the disease, which includes hepatoprotective, antioxidant, anticarcinogenic and anti-inflammatory activities; additionally, these compounds present advantages, as chemical diversity, low cost of production and milder or inexistent side effects. Objective: To present a broad perspective on hepatitis C infection, the chronic disease, and natural compounds with promising anti-HCV activity. Methods: This review consists of a systematic review study about the natural bioactive compounds as a potential therapy for hepatitis C infection. Results: The quest for natural products have yielded compounds with biologic activity, including viral replication inhibition in vitro, demonstrating antiviral activity against hepatitis C. Conclusion: One of the greatest advantages of using natural molecules from plant extracts is the low cost of production, not requiring chemical synthesis, which can lead to less expensive therapies available to low and middle-income countries.

scholarly journals Bioactive Compounds Obtained from Polish “Marynka” Hop Variety Using Efficient Two-Step Supercritical Fluid Extraction and Comparison of Their Antibacterial, Cytotoxic, and Anti-Proliferative Activities In Vitro

Molecules ◽  
2021 ◽  
Vol 26 (8) ◽  
pp. 2366
Author(s):  
Katarzyna Klimek ◽  
Katarzyna Tyśkiewicz ◽  
Malgorzata Miazga-Karska ◽  
Agnieszka Dębczak ◽  
Edward Rój ◽  
...  
Keyword(s):  
Supercritical Fluid Extraction ◽  
Supercritical Fluid ◽  
Bioactive Compounds ◽  
Crude Extract ◽  
Normal Skin ◽  
Extraction Methods ◽  
Biological Properties ◽  
Added Value ◽  
Fluid Extraction

Given the health-beneficial properties of compounds from hop, there is still a growing trend towards developing successful extraction methods with the highest yield and also receiving the products with high added value. The aim of this study was to develop efficient extraction method for isolation of bioactive compounds from the Polish “Marynka” hop variety. The modified two-step supercritical fluid extraction allowed to obtain two hop samples, namely crude extract (E1), composed of α-acids, β-acids, and terpene derivatives, as well as pure xanthohumol with higher yield than that of other available methods. The post-extraction residues (R1) were re-extracted in order to obtain extract E2 enriched in xanthohumol. Then, both samples were subjected to investigation of their antibacterial (anti-acne, anti-caries), cytotoxic, and anti-proliferative activities in vitro. It was demonstrated that extract (E1) possessed more beneficial biological properties than xanthohumol. It exhibited not only better antibacterial activity against Gram-positive bacteria strains (MIC, MBC) but also possessed a higher synergistic effect with commercial antibiotics when compared to xanthohumol. Moreover, cell culture experiments revealed that crude extract neither inhibited viability nor divisions of normal skin fibroblasts as strongly as xanthohumol. In turn, calculated selectivity indexes showed that the crude extract had from slightly to significantly better selective anti-proliferative activity towards cancer cells in comparison with xanthohumol.

scholarly journals Formation of Amphiphilic Molecules from the Most Common Marine Polysaccharides, toward a Sustainable Alternative?

Molecules ◽  
2021 ◽  
Vol 26 (15) ◽  
pp. 4445
Author(s):  
Tiphaine Wong ◽  
Lorette Brault ◽  
Eric Gasparotto ◽  
Romuald Vallée ◽  
Pierre-Yves Morvan ◽  
...  
Keyword(s):  
Fatty Acid ◽  
Carboxylic Acid ◽  
Bioactive Compounds ◽  
Biological Properties ◽  
Cross Linking ◽  
Structural Modifications ◽  
Chemical Structures ◽  
Amphiphilic Molecules

Marine polysaccharides are part of the huge seaweeds resources and present many applications for several industries. In order to widen their potential as additives or bioactive compounds, some structural modifications have been studied. Among them, simple hydrophobization reactions have been developed in order to yield to grafted polysaccharides bearing acyl-, aryl-, alkyl-, and alkenyl-groups or fatty acid chains. The resulting polymers are able to present modified physicochemical and/or biological properties of interest in the current pharmaceutical, cosmetics, or food fields. This review covers the chemical structures of the main marine polysaccharides, and then focuses on their structural modifications, and especially on hydrophobization reactions mainly esterification, acylation, alkylation, amidation, or even cross-linking reaction on native hydroxyl-, amine, or carboxylic acid functions. Finally, the question of the necessary requirement for more sustainable processes around these structural modulations of marine polysaccharides is addressed, considering the development of greener technologies applied to traditional polysaccharides.

scholarly journals Bioactive Compounds in Salicornia patula Duval-Jouve: A Mediterranean Edible Euhalophyte

Foods ◽  
2021 ◽  
Vol 10 (2) ◽  
pp. 410
Author(s):  
Irene Sánchez-Gavilán ◽  
Esteban Ramírez ◽  
Vicenta de la Fuente
Keyword(s):  
Fatty Acids ◽  
Bioactive Compounds ◽  
Mediterranean Area ◽  
Biological Properties ◽  
Total Phenolic ◽  
Tinto River ◽  
New Findings ◽  
High Concentrations ◽  
Salicornia Patula ◽  
First Time

Many halophytes have great nutritional and functional potential, providing chemical compounds with biological properties. Salicornia patula Duval-Jouve is a common euhalophyte from saline Mediterranean territories (Spain, Portugal, France, and Italy). In the present work we quantified for the first time the bioactive compounds in S. patula (total phenolic compounds and fatty acids), from Iberian Peninsula localities: littoral-coastal Tinto River basin areas (southwest Spain, the Huelva province), and mainland continental territories (northwest and central Spain, the Valladolid and Madrid provinces). Five phenolic acids including caffeic, coumaric, veratric, salicylic, and transcinnamic have been found with differences between mainland and coastal saltmarshes. S. patula contain four flavonoids: quercetin-3-O-rutinoside, kaempferol/luteolin, apigenin 7-glucoside, and pelargonidin-3-O-rutinoside. These last two glycosylated compounds are described for the first time in this genus of Chenopodiaceae. The fatty acid profile described in S. patula stems contains palmitic, oleic, and linoleic acids in high concentrations, while stearic and long-chain fatty acids were detected in low amounts. These new findings confirm that S. patula is a valuable source of bioactive compounds from Mediterranean area.

scholarly journals The synthesis and characterization of some new diazoamino derivatives

2010 ◽  
Vol 16 (1) ◽  
pp. 89-95
Author(s):  
Mihaela Mocanu
Keyword(s):  
1H Nmr ◽  
Bioactive Compounds ◽  
Elemental Analysis ◽  
Analysis Data ◽  
Biological Properties ◽  
Synthesis And Characterization ◽  
Elemental Analysis Data ◽  
Spectral Measurements ◽  
Inflammatory Processes

The sulfonamidic moiety is much encountered in structures of bioactive compounds. In the present paper the studies on the sulfonamidated aryloxyalkylcarboxylic acids are extended by their attaching on certain substrata able to confer some special biological properties to the final products, such as anti-tumor and antioxidant actions useful in treating inflammatory processes, ulcer, convulsions and diabetes, as well as a herbicidal action. The stepwise syntheses of the sulfonamidated aryloxyalkylcarboxylic acid derivatives and their characterization by elemental analysis data and IR, 1H-NMR and UV-Vis spectral measurements are described. The newly obtained compounds could show potential pharmaceutical and herbicide properties.

scholarly journals Isolation, Culture and Comprehensive Characterization of Biological Properties of Human Urine-Derived Stem cells

2021 ◽  
Vol 22 (22) ◽  
pp. 12503
Author(s):  
Martina Culenova ◽  
Andreas Nicodemou ◽  
Zuzana Varchulova Novakova ◽  
Michaela Debreova ◽  
Veronika Smolinská ◽  
...  
Keyword(s):  
Stem Cells ◽  
Low Cost ◽  
Biological Properties ◽  
Cytokine Profile ◽  
Rice Grain ◽  
Differentiation Potential ◽  
Secretory Rate ◽  
Gm Csf ◽  
Non Invasive ◽  
Cell Doubling Time

Mesenchymal stem cells (MSCs) represent an attractive source within the field of tissue engineering. However, their harvesting often requires invasive medical procedures. Urine-derived stem cells (UDSCs) display similar properties to MSCs, and their obtention and further processing is non-invasive for the donors as well as low cost. Here, we offer a comprehensive analysis of their biological properties. The goal of this study was to analyze their morphology, stemness, differentiation potential and cytokine profile. We have successfully isolated UDSCs from 25 urine samples. First colonies emerged up to 9 days after the initial seeding. Cell doubling time was 45 ± 0.24 SD, and when seeded at the density of 100 cells/cm2, they formed 42 ± 6.5 SD colonies within 10 days. Morphological analyzes revealed that two different types of the cell populations have been present. The first type had a rice-grain shape and the second one was characterized by a polyhedral shape. In several cell cultures, dome-shaped cells were observed as well. All examined UDSCs expressed typical MSC-like surface markers, CD73, CD90 and CD105. Moreover, conditioned media from UDSCs were harvested, and cytokine profile has been evaluated showing a significantly higher secretory rate of IL-8, IL-6 and chemokines MCP-1 and GM-CSF. We have also successfully induced human UDSCs into chondrogenic, osteogenic and myogenic cell lineages. Our findings indicate that UDSCs might have immense potential in the regeneration of the damaged tissues.

scholarly journals A Fast, Straightforward and Inexpensive Method for the Authentication of Baijiu Spirit Samples by Fluorescence Spectroscopy

Beverages ◽  
2021 ◽  
Vol 7 (3) ◽  
pp. 65
Author(s):  
Rachel L. Burns ◽  
Raegan Alexander ◽  
Liliya Snaychuk ◽  
John C. Edwards ◽  
Neil Fitzgerald ◽  
...  
Keyword(s):  
Analytical Chemistry ◽  
North America ◽  
Fluorescence Spectroscopy ◽  
Emission Spectroscopy ◽  
Low Cost ◽  
Fluorescence Emission ◽  
Wide Distribution ◽  
Inexpensive Method ◽  
Scientific Methods ◽  
Price Differences

The Chinese spirit baijiu is currently the world’s bestselling spirit, with more than ten billion liters sold in 2018. This is a figure that puts its sales higher than whiskey, vodka, gin, and tequila combined. The multitude of baijiu varieties available in the market differ in several ways ranging from aging to the traditional artisanship involved in producing the final spirit to several other features, including the rarity of the bottle. A result of these differences is a wide distribution of prices for the various baijiu products. Consequently, a single bottle of baijiu can cost anywhere from a few dollars, up to thousands of US dollars. The price differences among the various baijiu spirits necessitate the existence of reliable scientific methods that can efficiently differentiate and authenticate the qualities of baijiu spirits. In addition, the existence of such methods facilitates the prevention of counterfeit sales of the final product. Considering this, we introduce an analytical chemistry method that distinguishes amongst different baijiu spirits based on fluorescence spectroscopy. Its attributes include the low cost and convenience that allows analysis either before or while the spirit is in the market. Our work herein focuses on the analysis of thirty different varieties of baijiu spirits from six different distilleries from East Asia and North America by fluorescence emission spectroscopy, which is associated to the price of the product. For the analysis, we employed a HORIBA FLUOROLOG 3 (HORIBA—Jobin Yvon) spectrometer. Major advantages of this method include the low cost, as no consumables except a quartz reusable cuvette are required, the minimal waste, and finally the quick processing of data.

Making and Trading Dress and Décor in Seventeenth-century Scotland

2021 ◽  
Vol 100 (3) ◽  
pp. 419-436
Author(s):  
T. C. Smout
Keyword(s):  
Seventeenth Century ◽  
Comparative Advantage ◽  
Low Cost ◽  
Wide Distribution ◽  
Economic Stress ◽  
Textile Production ◽  
Limited Impact ◽  
The Social ◽  
Rural Wages ◽  
Made In

In seventeenth-century Scotland textiles were made in most districts and marketed widely at home and overseas. Woollens and linens, yarn, cloth, bonnets and stockings, with clear regional specialisations, were manufactured, but they were all of low cost and quality. Comparative advantage came from low rural wages. The wide distribution and character of textile production in the seventeenth century proved of great importance for post-Union success. Among imports the variety and social spread of luxury widened and deepened, though demand was restricted to the upper classes and the middling orders in Edinburgh and other large burghs. The seventeenth century, especially the second half, was a time of widening consumption of exotic articles such as tobacco, sugar and coffee among consumables, Asian silks and cottons (and their imitations) as articles of dress, and wall-hangings and pictures as décor. The social anxiety and economic stress this engendered gave rise to sumptuary laws like that of 1681. These had limited impact, though imports remained sensitive to tariffs. The letters of Andrew Russell, a merchant resident in Rotterdam between 1668 and 1697, demonstrate how this trade was carried out in both directions, and how the market responded to governmental attempts at control.

A low-cost optical sensor to quantify bioactive compounds in fruit

2020 ◽  
Vol 14 (6) ◽  
pp. 3580-3589 ◽  
Author(s):  
João Isaac Silva Miranda ◽  
Mônica Maria de Almeida Lopes ◽  
Kellina Oliveira de Souza ◽  
Hilton Andrade Pinho ◽  
Marcela Cristina Rabelo ◽  
...  
Keyword(s):  
Bioactive Compounds ◽  
Optical Sensor ◽  
Low Cost

scholarly journals Alternative methods for Salt free / Less salt short term preservation of hides and skins in leather making for sustainable development – A review

2019 ◽  
Vol 2 (1) ◽  
pp. 46-52 ◽  
Author(s):  
Venkatasubramanian Sivakumar ◽  
Resmi Mohan ◽  
Chellappa Muralidharan
Keyword(s):  
Sodium Chloride ◽  
Environmental Concern ◽  
Treatment Method ◽  
Alternative Methods ◽  
Waste Streams ◽  
Short Term ◽  
Leather Processing ◽  
Disposal Option ◽  
Patent Literature ◽  
Ultra Filtration

During the leather processing, large quantities of the salt as sodium chloride, about 30-50 % (% w/w on raw weight) is applied for short term preservation of hides and skins, which subsequently leaches out from the skins/hides and end up in waste streams. This raises a serious environmental concern as well as total dissolved solids (TDS) problem in the wastewater, for which there is no viable treatment method available. Remediation measures such as Reverse Osmosis (RO) or Ultra Filtration (UF) could only separate salt from these waste streams and end up as salt sludge, which necessitates Secured Land Fill (SLF) for disposal option. There are some concerns for SLF as it requires Land area as well as possible leaching due to highly soluble nature of Sodium chloride. Therefore, there is a pressing need for developing an alternative methods for Salt free / Less salt short term preservation of hides and skins. In this regard, Research and Development work is being carried out worldwide and several reports are available. Therefore, it would be beneficial to review and analyze the salt free alternative preservation methods. Even though, some reviews on this topic has been reported earlier, they have not taken into account the patent literature available on this subject. The present paper reviews various alternative methods for Salt free / Less salt short term preservation of hides and skins, taking into account both patent and other publications on this subject.

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