scholarly journals The Relationship of 25(OH)D3 with Diabetes Mellitus and the Mediation Effect of Lipid Profile in Chinese Rural Population of Henan Province

Medicina ◽  
2022 ◽  
Vol 58 (1) ◽  
pp. 85
Author(s):  
Mimi Zhang ◽  
Fei Yu ◽  
Yuan Xue ◽  
Lulu Song ◽  
Mengsi Du ◽  
...  

Background and Objectives: Studies suggest that vitamin D is involved in the development of type 2 diabetes mellitus (T2DM) and influences serum lipids levels, while lipid disorders are also closely related to T2DM. This study attempts to explore the complex relationship of serum 25(OH)D3, serum lipids, and T2DM among Chinese population. Materials and Methods: A cross-sectional study was carried out among 2326 subjects. The chi-square (χ2) test was applied to compare the prevalence of T2DM or dyslipidemia between two serum 25(OH)D3 levels. Linear regression was applied to analyze the correlation between serum lipids and 25(OH)D3 contents. Univariate and logistic analysis were used to explore the relationship between two lipid levels and T2DM. Mediation analysis was used to explore whether serum lipids mediate the relationship between two serum 25(OH)D3 levels and T2DM. Results: Compared to subjects with 25(OH)D3 ≥ 30 ng/mL, subjects with 25(OH)D3 < 30 ng/mL were higher in the prevalence of T2DM. The occurrences of high TG and low HDL-C were significantly higher in vitamin D deficiency and insufficiency than those in vitamin D sufficiency. Serum 25(OH)D3 content showed a reverse correlation with TC, TG, and LDL-C, but positive correlation with HDL-C. The odds ratios (ORs) (95% confidence intervals, 95%CI) of T2DM by comparing TG ≥ 2.26 mmol/L vs. TG < 2.26 mmol/L and HDL-C < 1.04 mmol/L vs. HDL-C ≥ 1.04 mmol/L in all participants were 2.48 (1.94–3.18) and 1.37 (1.07–1.75), respectively. Serum TG or HDL-C level partially mediated the relationship between two 25(OH)D3 level and T2DM. Conclusions: Serum 25(OH)D3 < 30 ng/mL seems to be associated with T2DM or dyslipidemia (high TG and low HDL-C) in our study, but there is still no proof of a cause–effect relationship. Moreover, serum TG or HDL-C level partially mediated the relationship between 25(OH)D3 levels and T2DM.

2018 ◽  
Vol 3 (1) ◽  
pp. 24 ◽  
Author(s):  
Eri H. Jubhari ◽  
Wahipa Wiro ◽  
Sinaryanti Sinaryanti

Objective: This study aim to determine the relationship between teeth color value and skin color value of the Makassar tribe.Material and Methods: This observational analytic research employs cross-sectional study and purposive sampling methods, with 73 samples; held in May 2012 in Bontoramba, Jeneponto district, South Sulawesi, Indonesia. It uses the Vita-Lumina shade guide for teeth color tests and Garnier FD344110.122.007 for skin color tests.Results: The results show that the distribution of teeth colour value in respondents is mostly in the highest values (A1, B1, A2, B2 color) which were 71.2%, while the skin value is mostly in a dark skin color (78.1%). Data was analyzed by the chi-square test. It was found that teeth color value was not related to skin color value in the Makassar tribe (p>0.05).Conclusion: Skin color value was not an indicator in determining the teeth color in the Makassar tribe.


2020 ◽  
Vol 5 (2) ◽  
pp. 162-173
Author(s):  
Rahmi Sibagariang ◽  
Muhammad Edy Syahputra Nasution ◽  
Siti Masliana Siregar ◽  
Isra Thristy

Obesity is an increase in total body fat, that is if found to be overweight > 20% in men and 25% in women due to fat. Increased obesity cannot beseparated from lifestyle, such as decreased physical activity.    One complication   that   can   be   caused   by   obesity   is   hearing   loss, especiallysensorineural hearing loss caused by microangiopathic abnormalities, especially in the inner ear. But the relationship of events between obesity withhearing loss is still often a debate, because there is no definite consensus. The purpose of this research determine the relationship of obesity with sensorineural hearing loss. This research is an analytic study by obtaining cross-sectional study, with data obtained from the assessment of bodyweight and height to see the status of the mass index, physical examination of the ear, and audiometric examination. Data analysis techniques using the chi square test statistics. Research result obtained relationship between obesity with sensorineural hearing loss as much as 49.09% and the highest degree of hearing loss is mild degrees as much as 27.07%. Research conclusions there is a significant relationship between obesity with sensorineural hearing loss. Keyword:  Hearing Loss, Obesity, Obesity with Hearing Loss, Pure Tone Audiometry, Sensorineural Hearing Loss,


2019 ◽  
Vol 7 (1) ◽  
Author(s):  
Jesica S. Lonto ◽  
Adrian Umboh ◽  
Abram Babakal

Abstract : Parenting is a pattern of interaction between parents and children. Children and snack foods are two things that are difficult to resolve because children have a penchant for more food, especially children of primary school age. The Purpose of this study is to find out the relationship between parenting and school children's snacking behavior aged 9-12 years at SD GMIM Sendangan. The Method of this study uses cross-sectional study design, using the chi-square test, with total sampel taken amounted to 64 people. The Conclusions based on the results of the analysis using the Chi-Square test show that there is the relationship of Parenting with Snacking behavior in Children’s schools aged 9-12 years at SD GMIM Sendangan Sonder with a significant value = 0.007 less than α 0.05.Keywords : Parenting , Snacking BehaviorAbstrak : Pola asuh orang tua merupakan pola interakasi antara orang tua dan anak. Anak-anak dan makanan jajanan merupakan dua hal yang sulit untuk dipisahkan karena anak-anak memiliki kegemaran untuk mengkonsumsi jenis makanan secara berlebihan, khususnya anak-anak usia sekolah dasar. Tujuan Penelitian : Untuk mengetahui Hubungan pola asuh orang tua dengan perilaku jajan anak sekolah Usia 9-12 Tahun di SD GMIM Sendangan. Desain Penelitian ini menggunakan penelitian cross sectional, dengan menggunakan uji chi-square dan teknik total sampling dengan jumlah sampel sebanyak 64 orang. Kesimpulan berdasarkan hasil analisis dengan menggunakan uji statistik chi-Square menunjukan terdapat hubungan Pola Asuh Orang Tua dengan Perilaku Jajan di sekolah Usia 9-12 Tahun di SD Gmim Sendangan Sonder dengan nilai signifikan = 0.007 atau kurang dari α 0.05.Kata Kunci : pola asuh orang tua, perilaku jajan


2017 ◽  
Vol 13 (2) ◽  
pp. 65-70
Author(s):  
Hariani Hariani ◽  
Deris Atma Subrin

Early menstruation in adolescents can be influenced by nutritional status and nutrients consumed by teenagers. This studyaims to determine the relationship of nutrient intake and nutritional status on the incidence of early menstruation at SMPN 1East Kabaena. This research is descriptive analytic with Cross Sectional Study. The population in this study were allstudents of SMPN 1 East Kabaena as many as 94 people. Sampling technique was purposive sampling. Data were obtainedusing a questionnaire and anthropometric measurements. Data were analyzed by using Chi-square test. Results show thatfrom 42 adolescents who consumed enough energy, there were 25 people (59.5%) experienced early menstruation, andfrom 38 adolescents who consumed less protein, there were 29 people (76.3%) experienced early menstruation. While the33 adolescents who consumed less fat, there were 25 people (75.8%) experienced early menstruation, and of 37 teenagerswho consumed more carbohydrates, there were 24 people (64.9%) had normal menstruation, while from 37 teenagers whohad over-nutrition status, there were 24 people (60.0%) had normal menstruation. The results show that there is arelationship between nutritional intake and nutritional status with the incidence of early menstruation in female students atSMPN 1 East Kabaena.


2019 ◽  
Vol 8 (1) ◽  
pp. 78
Author(s):  
Mariza Elvira ◽  
Novi Anggraini

Hypertension is a condition when blood pressure increases chronically. Ministry of Health (2007) states, mortality due to hypertension ranks second of total deaths from non-communicable diseases (12.3%). The purpose of this study was to determine the factors associated with the incidence of hypertension in polyclinic disease in RSUD Dr. Achmad Mochtar Bukittinggi. This study used descriptive analytic method with cross sectional study approach with 100 respondents and using correlation dynamics technique, research instrument is questionnaire by using chi-square statistic test. The result of the study (46%) had age 35-55 years old (51%) had bad diet, (51%) had high stress and 51% respondents consumed cigarettes. The result of statistic test was found on the association of age factor with the incidence of hypertension p-value 0.031, on the association of dietary factors with the incidence of hypertension obtained p-value 0.083, on the relationship of stress factor with hypertension occurrence obtained p-value 0.050 and on the relationship of smoking factor to the incidence Hypertension was obtained p-value 0.204, so it can be concluded from the four factors, only the age factor and stress factors that are related to the incidence of hypertension. It is expected that the health service can conduct an extension activity about hypertension which will be used as routine hospital program in improving health degree


2019 ◽  
Vol 4 (8) ◽  
pp. 474
Author(s):  
Litae Litae ◽  
Maria Magdalena Purba ◽  
Irene Febriani Febriani

Diabetes Mellitus (DM) is a medical disorder is a collection of symptoms caused by elevated levels of sugar or due to insulin resistance. DM is a non-communicable diseases. Riskesdas 2007 in Central Kalimantan diabetes prevalence of 0.9%, but were diagnosed by health personnel by 0.6%. While in the city of Palangkaraya. Prevalence of diabetes of 1.4%, but were diagnosed DM client just as much as 1.1%. This study aims to determine the relationship of the level of anxiety with increased blood sugar levels in diabetes mellitus clients in the region of Bukit Pukesmas Hindu city of Palangkaraya. Methods descriptive analytic cross sectional study design. The research sample as many as 65 people. The results showed that the DM Client Anxiety in Puskesmas Bukit Hindu city of Palangkaraya that her blood sugar levels <200 mg / dl was 23.1% mild anxiety and 24.6% were worried. Anxiety DM client that blood glucose levels> 200 mg / dl was 21.5% mild anxiety, and 30.8% were worried. Obtained a significant relationship between the level of anxiety with increased levels of sugar in clients with diabetes mellitus, where respondents blood sugar> 200 mg / dl with a moderate level of anxiety has peluag 5.787 times greater risk than the volunteers were mild anxiety level.


2019 ◽  
Vol 7 (1) ◽  
Author(s):  
Vianthy Kundiman ◽  
Lucky Kumaat ◽  
Maykel Kiling

Abstract: Triage is a patient sorting activity based on the severity of trauma or illness that iscarried out immediately in a short time. Overcrowded conditions by patients in the ED due tothe incompatibility of patients with the number of overcrowded nurses have an impact on theaccuracy implementation of triage in patients aimed at reducing morbidity and mortality.Thepurpose was to identify the relationship of overcrowded conditions and the accuracyimplementation of triage at ED of Pancaran Kasih GMIM Hospital Manado. The design studyis analytic survey with cross sectional.Samples 105 respondents with a Non Probabilitysampling technique namely Consecutive sampling. Results used the Chi square test with asignificance level of 95% so that the value of p value is 0,000 smaller than the significant valueof 0.05.Conclusion there is a relationship of overcrowded conditions and the accuracyimplementation of the truage at Emergency Department of Pancaran Kasih GMIM HospitalManado..Keywords: Triage, Overcrowded, AccuracyAbstrak: Triase merupakan kegiatan pemilahan pasien berdasarkan berat dan ringannya traumaatau penyakit yang diderita yang dilakukan segera dalam waktu yang singkat. Kondisiovercrowded oleh pasien di IGD disebabkan karena tidak sesuainya jumlah pasien denganjumlah perawat Overcrowded berdampak pada ketepatan pelaksanaan triase pada pasien yangbertujuan menurunkan angka morbiditas dan mortalitas. Tujuan untuk mengetahui hubunganantara kondisi overcrowded dengan ketepatan pelaksanaan triase di IGD RSU GMIM PancaranKasih Manado. Metode menggunakan desain penelitian cross sectional study. Sampel terdiridari 105 responden dengan tehnik pengambilan sampel Non Probability sampling yaituConsecutive sampling. Hasil menggunakan uji Chi square dengan tingkat kemaknaan 95%sehingga didapatkan nilai p value yaitu 0,000 lebih kecil dari nilai signifikan 0,05. Kesimpulanterdapat hubungan antara kondisi overcrowded dengan ketepatan pelaksanaan triase di IGDRSU GMIM Pancaran Kasih Manado.Kata Kunci: Triase, Overcrowded, Ketepatan


2019 ◽  
Vol 1 (1) ◽  
pp. 49-57
Author(s):  
Susi Susi ◽  
Didin Kustantiningtyastuti ◽  
Yona Ladyventini

Dental caries and gum disease (gingivitis) is a disease which are often found in elementary school’s student in Indonesia. One of the cause of the oral and dental problems  is behavior factor or neglect of oral hygiene. This study aims to determine the relationship of children's behaviors to health and dental hygiene with caries incidence in permanent first molars in SDN 15 Eastern District of  Padang. The design of this study is the Cross Sectional Study. The research was conducted at the Elementary School District 15 East Padang Padang Padang in January 2012. This study sample was a student of class IV, V, VI amounted to 80 people. The data was collected through questionnaires and dental examinations by chi-square analysis.


2017 ◽  
Vol 33 (4) ◽  
pp. 167
Author(s):  
Nine Luthansa ◽  
Dibyo Pramono

Body mass index and incidence of diabetes mellitus in adult population in Indonesia: analysis of IFLS data 5PurposeThis study aimed to determine the relationship between BMI with DM incidence in the adult population in Indonesia.MethodsThis cross sectional study was conducted using the 5th Indonesian Family Life Survey (IFLS5) data which is a collaboration of the RAND corporation and Survey Meter. Chi square and logistic regression tests were used to analyze the relationship between BMI and DM incidence. BMI was obtained through measurement of body weight and height in respondents aged > 18 years. Information on the incidence of DM was obtained from interviews with respondents.ResultsThere were 22,647 subjects who met the study criteria. The proportion of DM in this study was 2.89%. People with obese BMI had a higher risk of developing DM than people with underweight BMI (OR = 3.15; 95% CI = 2.05- 4.82). After adjusting for gender, age, and education variables, the risk remained significant (OR = 3.29; 95% CI = 2.14-5.065).ConclusionBody mass index is associated with the incidence of diabetes mellitus, in which people with excessive BMI or obese have a greater risk of developing DM than people with underweight BMI.


2021 ◽  
Vol 12 ◽  
Author(s):  
João Soares Felício ◽  
Hana Andrade de Rider Britto ◽  
Pedro Celeira Cortez ◽  
Fabrício de Souza Resende ◽  
Manuela Nascimento de Lemos ◽  
...  

BackgroundThe effect of glycemic control on diabetic kidney disease (DKD) is well known. Recent evidence has suggested that Vitamin D (VD) may have a nephroprotective effect in diabetes, but the relationship between VD, glycemic control, and albuminuria has yet to be clarified.ObjectiveEvaluate the relationship between 25-hydroxy-vitamin D [25(OH)D], HbA1c, and albuminuria in Diabetes Mellitus (DM).Patients and MethodsCross-sectional study with 1576 individuals with DM who had 25(OH)D, HbA1c, and albuminuria levels measured. Patients with abnormal creatinine levels were excluded, in order to avoid interference on VD levels by impaired kidney function.ResultsPatients with HbA1c ≥7% had lower 25(OH)D when compared to patients with HbA1c &lt;7% (29.7 ± 10.2 vs 28.1 ± 9.9 ng/ml, p = 0.003) and 25(OH)D levels seems to predict 1.5% of HbA1c behavior. The 25(OH)D concentrations in patients with normoalbuminuria were higher than the levels observed in those with micro or macroalbuminuria (29.8 ± 9.0 vs 26.8 ± 8.6 and 25.1 ± 7.6, respectively, p = 0.001), patients who had 25(OH)D &lt;20 ng/ml and 25(OH)D &lt;30 ng/ml were at a higher risk of presenting albuminuria [OR = 2.8 (95% CI = 1.6 – 4.9), p&lt;0.001, and OR = 2.1 (95% CI = 1.3 - 4.6), p&lt;0.001, respectively]. In our regression model, albuminuria was influenced by HbA1c (r² = 0.076, p&lt;0.00001) and 25(OH)D (r² = 0.018, p = 0.002) independently.ConclusionOur study found an association between vitamin D levels, HbA1c and DKD. Additionally, our data suggest that the association between urinary albumin excretion and vitamin D levels is independent of glycemic control in patients with diabetes. Even though our patients presented normal creatinine levels, it is necessary further prospective studies to confirm if this association precedes or not the loss of renal function.


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