A COVID-19 Hotspot Area: Activities and Epidemiological Findings

By late March 2020, Villa Caldari, a small village of the municipality of Ortona (Abruzzo region), was registering an incidence rate of COVID-19 cases ten times greater than the overall municipality and was declared a hotspot area. Twenty-two days later, epidemiological investigation and sampling were performed, to evaluate SARS-CoV-2 circulation and the presence of SARS-CoV-2 antibodies. Overall, 681 nasopharyngeal swabs and 667 blood samples were collected. Only one resident of the village resulted in being positive for RNA viral shedding, while 73 were positive for SARS-CoV-2 antibodies. The overall seroprevalence was 10.9%. The difference between the seroprevalence of infection in asymptomatic and symptomatic individuals was significant (χ2 = 14.50 p-value = 0.0001). Amongst the residents positive for antibodies, fatigue and/or muscle pain, fever and anosmia were the most experienced symptoms, whose most frequent onset was observed during the first two weeks of March. Familial and habit-related clusters were highlighted. Nevertheless, the investigations showed a low SARS-CoV-2 circulation in the village at the time of the sampling, demonstrating virus transmission could be limited when strict emergency measures are followed. Given the favorable results, the emergency measures were then lifted.

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Pengaruh pendidikan mitigasi bencana tanah longsor terhadap kesiapsiagaan masyarakat didesa melung kecamatan kedungbanteng kabupaten banyumas

Jurnal Keperawatan Muhammadiyah ◽

10.30651/jkm.v5i2.4906 ◽

2020 ◽

Vol 5 (2) ◽

Author(s):

Rachmi Ariyani ◽

Endiyono - Endiyono

Keyword(s):

Quantitative Methods ◽

Knowledge Society ◽

Statistical Test ◽

Disaster Mitigation ◽

P Value ◽

The People ◽

The Difference ◽

The One ◽

The Village ◽

Landslide Disaster

Objective: Understand Effect of Education Mitigation of Disasters Land landslide against Preparedness Society in Rural Melung District of Kedungbanteng Regency of Banyumas. Methods: This study uses quantitative methods with quasy experimental designs through the one group pretest-posttest design approach. Test were used in research this is a test paired sample t test with a number of 50 respondents were taken by proposive sampling. Results: Result statistical test p-value = 0.0001 ( p-value < 0.05) which means that there are significant landslide disaster mitigation education to the knowledge society in the village of the District Melung Kedungbanteng Banyumas Regency. This influence is indicated by an increase of 5,640 points from the score before training of 6,140. The difference of 5,640 is statistically significant.Conclusion: The preparedness of the village community in melung is included in the category of being ready to face the possibility of a landslide disaster, before the training knowledge of the people of 6,15 but after the knowledge of the rise of 11,78.Keywords: Mitigation disasters soil landslides, Preparednes, Education.

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The difference of oral hygiene status between ethnic group Minang and Sundanese in Pangalengan aged 26-45 years old

Padjadjaran Journal of Dentistry ◽

10.24198/pjd.vol25no1.26780 ◽

2013 ◽

Vol 25 (1) ◽

Author(s):

Efru Rinaldy ◽

Sjazili Muhibat ◽

Anne Agustina Suwargiani

Keyword(s):

Ethnic Group ◽

Oral Hygiene ◽

Sampling Method ◽

P Value ◽

Research Use ◽

Ethnic Communities ◽

Descriptive Research ◽

The Status ◽

The Difference ◽

The Village

Introduction: Indonesia has a lot of different languages, customs, and food. Each ethnic has a distinctive food of each such Minang ethnic happy with spicy foods and coconut milk, while Sundanese pleased with foods that are sweet and dry. The purpose of this study was to determine the status of oral hygiene ethnic group Minang and Sundanese. Methods: This research use descriptive research. The method used in the study are the type of total sampling method. Samples will be selected according to the criteria of the indigenous people the Minang ethnic and Sundanese ethnic who live in the village Pangalengan district as many as 33 people Minang ethnic and 66 people Sundanese ethnic as a control. Results: Results showed a p-value of oral hygiene status in Minang ethnic communities and Sundanese ethnic communities in Pangalengan is 0.261. Oral hygiene status in Minang ethnic communities in the district Pangalengan are in the medium category with the numbers 2.7, while the Sundanese people are in the medium category with the numbers 2.4. Conclusion: The conclusions of this study is there is no difference of oral hygiene status between Minang ethnic and Sundanese ethnic in Pangalengan age of 26-45 years.

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Consequences of Succinylcholine Administration to Patients Using Statins

Anesthesiology ◽

10.1097/aln.0b013e31822079fa ◽

2011 ◽

Vol 115 (1) ◽

pp. 28-35 ◽

Cited By ~ 9

Author(s):

Alparslan Turan ◽

Maria L. Mendoza ◽

Shipra Gupta ◽

Jing You ◽

Alexandru Gottlieb ◽

...

Keyword(s):

Creatine Kinase ◽

Muscle Pain ◽

Muscle Injury ◽

Structural Changes ◽

Plasma Concentrations ◽

Plasma Potassium ◽

Clinical Consequence ◽

Blood Samples ◽

Study Results ◽

The Difference

Background Statins cause structural changes in myocytes and provoke myotoxicity, myopathy, and myalgias. Thus, patients taking statins may be especially susceptible to succinylcholine-induced muscle injury. The authors tested the hypothesis that succinylcholine increases plasma concentrations of myoglobin, potassium, and creatine kinase more in patients who take statins than in those who do not and that succinylcholine-induced postoperative muscle pain is aggravated in statin users. Methods Patients who took statins for at least 3 months and those who had never used statins were enrolled. General anesthesia was induced and included 1.5 mg/kg succinylcholine for intubation. The incidence and degree of fasciculation after succinylcholine administration were recorded. Blood samples were obtained before induction and 5 and 20 min and 24 h after succinylcholine administration. Patients were interviewed 2 and 24 h after surgery to determine the degree of myalgia. Results The authors enrolled 38 patients who used statins and 32 who did not. At 20 min, myoglobin was higher in statin users versus nonusers (ratio of medians 1.34 [95% CI: 1.1, 1.7], P = 0.018). Fasciculations in statin users were more intense than in nonusers (P = 0.047). However, plasma potassium and creatine kinase concentrations were similar in statin users and nonusers, as was muscle pain. Conclusions The plasma myoglobin concentration at 20 min was significantly greater in statin users than nonusers, although the difference seems unlikely to be clinically important. The study results suggest that the effect of succinylcholine given to patients taking statins is likely to be small and probably of limited clinical consequence.

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Motivasi dan kepuasan kerja pegawai puskesmas BLUD dan non-BLUD Kabupaten Semarang

Health Sciences and Pharmacy Journal ◽

10.32504/hspj.v2i3.45 ◽

2018 ◽

Vol 2 (3) ◽

pp. 111

Author(s):

Aswindar Adhi Gumilang ◽

Tri Pitara Mahanggoro ◽

Qurrotul Aini

Keyword(s):

Public Health ◽

Job Satisfaction ◽

Financial Management ◽

Work Motivation ◽

P Value ◽

The Public ◽

The Status ◽

The Difference ◽

Demand For Health ◽

Public Demand

The public demand for health service professionalism and transparent financial management made some Puskesmas in Semarang regency changed the status of public health center to BLUD. The implementation of Puskesmas BLUD and non-BLUD requires resources that it can work well in order to meet the expectations of the community. The aim of this study is to know the difference of work motivation and job satisfaction of employees in Puskesmas BLUD and non-BLUD. Method of this research is a comparative descriptive with a quantitative approach. The object of this research are work motivation and job satisfaction of employees in Puskesmas BLUD and non-BLUD Semarang regency. This Research showed that Sig value. (P-value) work motivation variable was 0.019 smaller than α value (0.05). It showed that there was a difference of work motivation of employees in Puskemas BLUD and non-BLUD. Sig value (P-value) variable of job satisfaction was 0.020 smaller than α value (0.05). It showed that there was a difference of job satisfaction of BLUD and non-BLUD. The average of non-BLUD employees motivation were 76.59 smaller than the average of BLUD employees were 78.25. The average of job satisfaction of BLUD employees were 129.20 bigger than the average of non-BLUD employee were 124.26. Job satisfaction of employees in Puskesmas BLUD was higher than non-BLUD employees.

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Perbedaan Penggunaan Antikoagulan K2EDTA DAN K3EDTA Terhadap Hasil Pemeriksaan Indeks Eritrosit

Jurnal Laboratorium Khatulistiwa ◽

10.30602/jlk.v1i2.147 ◽

2018 ◽

Vol 1 (2) ◽

pp. 114

Author(s):

Wahdaniah Wahdaniah ◽

Sri Tumpuk

Keyword(s):

Screening Test ◽

Venous Blood ◽

The Body ◽

Ethylene Diamine ◽

P Value ◽

Cross Sectional ◽

Significant Difference ◽

Ethylene Diamine Tetra Acetate ◽

The Difference ◽

Index Value

Abstract: Routine blood examination is the earliest blood test or screening test to determine the diagnosis of an abnormality. Blood easily froze if it is outside the body and can be prevented by the addition of anticoagulants, one of which Ethylene Diamine Tetra Acetate (EDTA). Currently available vacuum tubes containing EDTA anticoagulants in the form of K2EDTA and K3EDTA. K3EDTA is usually a salt that has better stability than other EDTA salts because it shows a pH approaching a blood pH of about 6.4. The purpose of this research is to know the difference of erythrocyte index results include MCH, MCV and MCHC using K3EDTA anticoagulant with K2EDTA. This research is a cross sectional design. This study used venous blood samples mixed with K2EDTA anticoagulant and venous blood mixed with K3EDTA anticoagulants, each of 30 samples. Data were collected and analyzed using paired different test. Based on data analysis that has been done on MCH examination, p value <0,05 then there is a significant difference between samples with K3EDTA anticoagulant with K2EDTA to erythrocyte index value. Then on the examination of MCV and MCHC obtained p value <0.05 then there is no significant difference between samples with K3EDTA anticoagulant with K2EDTA to erythrocyte index value.Abstrak: Pemeriksaan darah rutin merupakan pemeriksaan darah yang paling awal atau screening test untuk mengetahui diagnosis suatu kelainan. Darah mudah membeku jika berada diluar tubuh dan bisa dicegah dengan penambahan antikoagulan, salah satunya Ethylene Diamine Tetra Acetate (EDTA). Dewasa ini telah tersedia tabung vakum yang sudah berisi antikoagulan EDTA dalam bentuk K2EDTA dan K3EDTA. K3EDTA biasanya berupa garam yang mempunyai stabilitas yang lebih baik dari garam EDTA yang lain karena menunjukkan pH yang mendekati pH darah yaitu sekitar 6,4. Tujuan dari penelitian ini adalah untuk mengetahui perbedaan hasil indeks eritrosit meliputi MCH, MCV dan MCHC menggunakan antikoagulan K3EDTA dengan K2EDTA. Penelitian ini merupakan penelitian dengan desain cross sectional. Penelitian ini menggunakan sampel darah vena yang dicampur dengan antikoagulan K2EDTA dan darah vena yang dicampur dengan antikoagulan K3EDTA, masing-masing sebanyak 30 sampel. Data dikumpulkan dan dianalisis menggunakan uji beda berpasangan. Berdasarkan analisis data yang telah dilakukan pada pemeriksaan MCH didapatkan nilai p < 0,05 maka ada perbedaan yang signifikan antara sampel dengan antikoagulan K3EDTA dengan K2EDTA terhadap nilai indeks eritrosit. Kemudian pada pemeriksaan MCV dan MCHC didapatkan nilai p < 0,05 maka tidak ada perbedaan yang signifikan antara sampel dengan antikoagulan K3EDTA dengan K2EDTA terhadap nilai indeks eritrosit.

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PENGARUH PENDAPATAN RUMAH TANGGA TERHADAP KONSUMSI DAGING (SAPI, BABI DAN AYAM ) DI DESA SEA I KECAMATAN PINELENG

ZOOTEC ◽

10.35792/zot.34.2.2014.5522 ◽

2014 ◽

Vol 34 (2) ◽

pp. 10

Author(s):

Richie A.F. Osak ◽

V V.J Panelewen ◽

J. Pandey ◽

I. D.R Lumenta

Keyword(s):

Household Income ◽

Household Head ◽

Secondary Data ◽

Meat Consumption ◽

Research Problem ◽

Chicken Meat ◽

Primary Data ◽

Survey Method ◽

The Difference ◽

The Village

ABSTRACT THE EFFECT OF HOUSEHOLD INCOME ON MEAT CONSUMPTION (BEEF, PORK AND CHIKEN) AT THE VILLAGE OF SEA I, PINELENG DISTRICT.This study aims to determine the magnitude of meat consumption (beef, porl and chiken) of household based on income levels in the Village of Sea I, Pineleng district and to determine the effect of household income on meat consumption (beef, porl and chiken) in the Village of Sea I, Pineleng district. Formulation of research problem is how much they purchased meat (beef, porl and chiken) consumption household in the Village of Sea I, Pineleng district. This study was conducted in the Village of Sea I, Pineleng district. Study was conducted using a survey method, and data were obtained through primary data and secondary data. Determination of the location (rural sample) in the study was conducted by purposive sampling method. Number of samples used in this study were 30 people. Data of this study were analyzed by descriptive and mathematical analysis methods. Income indicated the amount of income earned in a month household, whether they were from the household head or sourced from other household members who work and earn income. From the money earned, the highest number of respondents had incomes between 1.000.000 to 3.000.000/month with the percentage of 70 %, while the number of respondents with the smallest income was less than 1.000.000/month with the percentage of 16.67 %. The difference of income held by the respondents in the Village of Sea I, would have an impact on the amount of meat purchases each month. This was in accordance with the opinion Sukirno (2002) stating that most of the disposable income is used to buy food and clothing. Most of the meat consumed by people in the Village of Sea I was pork and chicken meat compared to beef, it was because the price of beef was relatively expensive compared to the price of pork and chicken meat. Based on research results, pork was the most meat consumed by family respondents about 21 families with the percentage of 70 % of respondents, followed by chicken meat about 18 families with the percentage of 60 % of respondents, and beef by 8 families with the percentage of 26 respondents, 67 % of domestic poultry and meat about 6 families with the percentage of 20 % of respondents. Based on the results of research, it can be concluded that household income significantly affect the consumption of meat in the Village of Sea I, Pineleng district and the average consumption of meat in the Village of Sea I, Pineleng district was about 8,9 kg/capita/year, below the national target of 10,3 kg/capita/year. Key Words : Household income, meat consumption, Sea I Village.

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Assessment of Admission Time Cell Blood Count (CBC) Parameters in Predicting Post-primary Percutaneous Coronary Intervention TIMI Frame Count in Patients with ST-segment Elevation Myocardial Infarction

Cardiovascular & Haematological Disorders - Drug Targets ◽

10.2174/1871529x20666200206123118 ◽

2020 ◽

Vol 20 (3) ◽

pp. 191-197

Author(s):

Hossein Vakili ◽

Isa Khaheshi ◽

Amirsina Sharifi ◽

Negin Nickdoost ◽

Mohammad H. Namazi ◽

...

Keyword(s):

Myocardial Infarction ◽

Platelet Count ◽

P Value ◽

Primary Pci ◽

Blood Samples ◽

Timi Frame Count ◽

Admission Time ◽

No Reflow ◽

Corrected Timi Frame Count ◽

No Reflow Phenomenon

Objectives: In this study, we aimed to assess the value of admission time CBC parameters in predicting post-primary PCI corrected TIMI frame count. Background: Recent years have witnessed a large series of studies evaluating different laboratory variables to predict no-reflow phenomenon following primary PCI (PPCI) in patients with STEMI. However, a general agreement about the most reliable predictor of the no-reflow phenomenon is challenging and also intriguing. Methods: The current study concluded 208 consecutive patients who underwent primary PCI for ST-Elevation Myocardial Infarction (STEMI) from January 2014 to February 2016. Blood samples were obtained after taking ECG. Complete blood samples were collected and analyzed within 5 minutes from sampling. Post-PCI corrected Thrombolysis in Myocardial Infarction (TIMI) frame count was determined by one interventional cardiologist blinded to patients’ clinical data. The correlation between admission time blood parameters and post-primary PCI corrected TIMI frame count in patients with STEMI were assessed. Results: Corrected TIMI frame count was positively correlated with WBC count (R: 0.18, P-value: <0.01), neutrophil count (R: 0.34, P-value: <0.01), and platelet count (R: 0.23, P-value: <0.01) and negatively correlated with lymphocyte count (R: -0.2, P-value: <0.01). Multiple linear regression results demonstrated that corrected TIMI frame count was positively correlated with neutrophil count (P < 0·001) and platelet count (P < 0·001) and negatively correlated with lymphocyte count (p=0.004). Conclusion: High counts of WBC, neutrophil, and platelet and low count of lymphocyte may be predictors of no-reflow in STEMI patients undergoing PPCI. The clinical significance of such predictive parameters becomes clear as we consider the treatment approach in STEMI patients. Appropriate risk stratification leads to better treatment planning and allocation of resources.

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Planning for End of Life

American Journal of Hospice and Palliative Medicine® ◽

10.1177/10499091211014166 ◽

2021 ◽

pp. 104990912110141

Author(s):

Natasha Ansari ◽

Eric Johnson ◽

Jennifer A. Sinnott ◽

Sikandar Ansari

Keyword(s):

End Of Life ◽

Treatment Options ◽

Stage Iv ◽

P Value ◽

Life Planning ◽

Number Of Patients ◽

End Of Life Planning ◽

The Difference ◽

Alternative Medications ◽

Patient’S Perception

Background: Oncology provider discussions of treatment options, outcomes of treatment, and end of life planning are essential to care for patients with advanced malignancies. Studies have shown that despite this, many patients do not have adequate care planning, including end of life planning. It is thought that the accessibility of information outside of clinical encounters and individual factors and/or beliefs may influence the patient’s perception of disease. Aims: The objective of this study was to evaluate if patient understanding of treatment goals matched the provider and if there were areas of discrepancy. If a discrepancy was found, the survey inquired further into more specific aspects. Methods: A questionnaire-based survey was performed at a cancer hospital outpatient clinic. 100 consecutive and consenting patients who had stage IV non-curable lung, gastrointestinal (GI), or other cancer were included in the study. Patients must have had at least 2 visits with their oncologist. Results: 40 patients reported their disease might be curable and 60 reported their disease was not curable. Patients who reported their disease was not curable were more likely to be 65 years or older (P-value: 0.055). They were more likely to report that their doctor discussed the possibility of their cancer getting worse (78.3% VS 55%; P-value 0.024), that their doctor discussed end of life plans (58.3% VS 30%; P- value: 0.01), and that they had appointed a health care decision-maker (86.7% VS 62.5%; P-value: 0.01). 65% of patients who thought their disease might be curable reported that their doctor said it might be curable, compared with only 6.7% of patients who thought their disease was not curable (p < 0.001). Or, equivalently, 35% of patients who thought their disease might be curable reported that their doctor’s opinion was that it was not curable, compared with 93% of patients who thought their disease was not curable (p < 0.001). Patients who had lung cancer were more likely to believe their cancer was not curable than patients with gastrointestinal or other cancer, though the difference was not statistically significant (p = 0.165). Patients who said their disease might be curable selected as possible reasons that a miracle (50%) or alternative medicine (66.7%) would get rid of the cancer, or said their family wanted them to believe the cancer would go away (16.7%) or that another doctor said it would (4.2%). Patients who said their disease might be curable said they did so due to alternative medications, another doctor, or their family. Restricting to the 70 patients who reported their doctors telling them their disease was not curable, 20% of them still said that they personally felt their disease might be curable. Patients below 65 years of age were more likely to disagree with the doctor in this case (P-value: 0.047). Conclusion: This survey of patients diagnosed with stage IV cancer shows that a significant number of patients had misunderstandings of the treatment and curability of their disease. Findings suggest that a notable proportion kept these beliefs even after being told by treating physicians that their disease is not curable.

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A Comparison of the Clinical and Radiological Extent of Denosumab (Xgeva®) Related Osteonecrosis of the Jaw: A Retrospective Study

Journal of Clinical Medicine ◽

10.3390/jcm10112390 ◽

2021 ◽

Vol 10 (11) ◽

pp. 2390

Author(s):

Zineb Assili ◽

Gilles Dolivet ◽

Julia Salleron ◽

Claire Griffaton-Tallandier ◽

Claire Egloff-Juras ◽

...

Keyword(s):

Retrospective Study ◽

Cumulative Incidence ◽

Side Effect ◽

Osteonecrosis Of The Jaw ◽

Exposed Group ◽

Severe Side Effect ◽

Dental Arch ◽

P Value ◽

The Difference ◽

Bone Exposure

Medication-related osteonecrosis of the jaw (MRONJ) is a severe side effect of antiresorptive medication. The aim of this study was to evaluate the incidence of denosumab-related osteonecrosis of the jaw and to compare the clinical and radiological extent of osteonecrosis. A retrospective study of patients who received Xgeva® at the Institut de Cancérologie de Lorraine (ICL) was performed. Patients for whom clinical and radiological (CBCT) data were available were divided into two groups: “exposed” for patients with bone exposure and “fistula” when only a fistula through which the bone could be probed was observed. The difference between clinical and radiological extent was assessed. The p-value was set at 0.05, and a total of 246 patients were included. The cumulative incidence of osteonecrosis was 0.9% at 6 months, 7% at 12 months, and 15% from 24 months. The clinical extent of MRONJ was significantly less than their radiological extent: in the “exposed” group, 17 areas (45%) were less extensive clinically than radiologically (p < 0.001) and respectively 6 (67%) for the “fistula” group (p < 0.031). It would seem that a CBCT is essential to know the real extent of MRONJ. Thus, it would seem interesting to systematically perform a CBCT during the diagnosis of MRONJ, exploring the entire affected dental arch.

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Does Consumption of Nitrate Containing Beetroot Juice Affect Indoor Rowing Performance in Males and Females?

Current Developments in Nutrition ◽

10.1093/cdn/nzaa066_009 ◽

2020 ◽

Vol 4 (Supplement_2) ◽

pp. 1754-1754

Author(s):

Giselle Greisman ◽

June Kloubec ◽

Alexandra Kazaks ◽

Kelly Morrow ◽

Cristen Harris

Keyword(s):

P Value ◽

Beetroot Juice ◽

Double Blind ◽

Male Athletes ◽

Funding Sources ◽

Beverage Type ◽

Rowing Performance ◽

Males And Females ◽

The Difference ◽

Research Grant

Abstract Objectives The nitrates found in beetroot juice (BR) are known to be a precursor of nitric oxide (NO). NO is a known vasodilator which allows more oxygen to travel in the blood and may improve muscle efficiency. This study aims to measure the effect of BR supplementation on performance on 500-meter row time for trained CrossFit athletes. Many past studies have analyzed the effect of BR on male athletes, this study aimed to include both males and females. Methods This study used a randomized, cross-over, double-blind, placebo-controlled design to measure 500-meter row time. Thirty athletes age 18–60 consumed either a 2.7 oz shot of BR (6.5 mmol nitrate) or a placebo nitrate-free beetroot juice (PL). Two hours later, they rowed 500 meters. After at least a seven-day washout period, athletes repeated the 500-meter row with either BR or PL for comparison. This study was performed from July 2019 – January 2020 and was conducted in Mercer Island, Washington. Results Ten males age 18.0 to 60.3 (median 47.7) and twenty females age 26.7 to 58.3 (median 43.8), participated in this study. Row times for the 500-meter row ranged from 88.2 seconds to 150.7 seconds. Data indicate that although 60% of all participants rowed faster with BR (mean 112.83 seconds), compared to PL (mean 113.40 seconds), the difference in the means of row times (−0.563) was not significant overall (P = 0.29). However, for the 10 males, row times were significantly faster (1.02 second difference, P = 0.04) on average with BR compared to PL. For the 20 females, the difference in mean row time (−0.335 seconds) was not significant (P = 0.66). Competitive rowers were defined as those who rowed under 110 seconds (N = 15). For competitive rowers (10 males, 5 females), row times were significantly faster with BR compared to PL (difference in means −0.94, P = 0.009). However, for those rowers, the P-value of drink * group was 0.015. Conclusions Dietary nitrate improved indoor rowing performance in males but not in females. In addition, competitive rowers were also significantly faster with BR, however, there may be an order bias, since there was significant interaction between beverage type and testing order. Food based nitrate supplements may increase rowing performance with male rowers. Funding Sources Supported by Bastyr Faculty Student Research Grant.

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