scholarly journals Higher Iron Intake Is Independently Associated with Obesity in Younger Japanese Type-2 Diabetes Mellitus Patients

Nutrients ◽  
2022 ◽  
Vol 14 (1) ◽  
pp. 211
Author(s):  
Efrem d’Ávila Ferreira ◽  
Mariko Hatta ◽  
Yasunaga Takeda ◽  
Chika Horikawa ◽  
Mizuki Takeuchi ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Vegetable Intake ◽  
Positive Trend ◽  
Inverse Association ◽  
Age Group ◽  
Food Groups ◽  
Iron Intake ◽  
Cross Sectional ◽  
Younger Age

We aimed to analyze the association between dietary iron intake and obesity assessed by BMI after adjustment for nutrient intake (macronutrients and fiber) and food groups. The study design was cross-sectional. Patients with type-2 diabetes (n = 1567; 63.1% males; mean age 62.3 ± 11.6 years) were included in the study. To assess diet, consumption of typical food groups was determined by a food frequency questionnaire. Obesity was defined as BMI ≥ 25 kg/m2. We performed a binary regression analysis between quartiles of iron intake and obesity by quartiles of age group. A direct linear association was found for the highest quartile of iron intake and obesity in the younger age group of 30 to 54 years (OR = 3.641, 95% CI = 1.020–12.990; p trend = 0.011). Multivariate analysis using food groups as opposed to nutrients revealed a positive trend for obesity in the younger age group after adjusting for lifestyle factors, energy intake and bean and vegetable intake (p trend = 0.023). In all participants, an inverse association was observed before adjustment by vegetable intake (OR = 0.453, 95% CI = 0.300–0.684; p trend = 0.001). Higher iron intake was associated with obesity independent of macronutrient and fiber intake but only in the youngest quartile of age group examined.

scholarly journals Sodium Intake and Incidence of Diabetes Complications in Elderly Patients with Type 2 Diabetes—Analysis of Data from the Japanese Elderly Diabetes Intervention Study (J-EDIT)

Nutrients ◽  
2021 ◽  
Vol 13 (2) ◽  
pp. 689
Author(s):  
Chika Horikawa ◽  
Rei Aida ◽  
Shiro Tanaka ◽  
Chiemi Kamada ◽  
Sachiko Tanaka ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Diabetic Retinopathy ◽  
Elderly Patients ◽  
Diabetes Complications ◽  
Vegetable Intake ◽  
Sodium Intake ◽  
Food Groups ◽  
High Sodium ◽  
Increased Risk

This study investigates the associations between sodium intake and diabetes complications in a nationwide cohort of elderly Japanese patients with type 2 diabetes aged 65–85. Data from 912 individuals regarding their dietary intake at baseline is analyzed and assessed by the Food Frequency Questionnaire based on food groups. Primary outcomes are times to diabetic retinopathy, overt nephropathy, cardiovascular disease (CVD), and all-cause mortality during six years. We find that mean sodium intake in quartiles ranges from 2.5 g to 5.9 g/day. After adjustment for confounders, no significant associations are observed between sodium intake quartiles and incidence of diabetes complications and mortality, except for a significant trend for an increased risk of diabetic retinopathy (p = 0.039). Among patients whose vegetable intake was less than the average of 268.7 g, hazard ratios (HRs) for diabetic retinopathy in patients in the second, third, and fourth quartiles of sodium intake compared with the first quartile were 0.87 (95% CI, 0.31–2.41), 2.61 (1.00–6.83), and 3.70 (1.37–10.02), respectively. Findings indicate that high sodium intake under conditions of low vegetable intake is associated with an elevated incidence of diabetic retinopathy in elderly patients with type 2 diabetes.

scholarly journals Prevalence of depression among patients with type 2 diabetes mellitus: a cross-sectional study

2019 ◽  
Vol 6 (5) ◽  
pp. 1372
Author(s):  
Sanjay Parihar ◽  
Rajesh Singh
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Family History ◽  
Age Group ◽  
Duration Of Treatment ◽  
Cross Sectional ◽  
Prevalence Of Depression ◽  
History Of

Background: Depression can be viewed as a modifiable independent risk factor for the development of T2DM and for progression of complications from either type 1 or type 2 diabetes. The recognition and addressal of this association can have profound implications for prevention and treatment of these disorders. Objectives of this study the prevalence of depression among patients with diabetes mellitus type 2.Methods: A semi-structured questionnaire was used to collect the sociodemographic profile and the details of the diabetes and its treatment and history of other chronic diseases. Beck depression inventory (BDS-II) was used for evaluation of depression and 8 item Morisky medication adherence scale (MMAS-8) was used for measurement of patient’s adherence to medication.Results: Majority of the potential cases of depression (33%) were in the age group of 51-60 years. 62% of the patients were male. Majority of the patients (40%) were in the age group of 51-60 years. 73.4% of the married patients were potential cases of depression. 78% of the patients were having family history of type 2 diabetes mellitus. Majority of the patients (72%) were overweight or obese (BMI> 25kg/m2).Conclusion: Duration of diabetes and duration of treatment was 5-10 years in majority of the patients and were significantly associated with prevalence of depression. Prevalence of depression was associated with sex, religion, and family history but was not statistically significant.

scholarly journals Calcium Phosphate Product Is Associated with Subclinical Carotid Atherosclerosis in Type 2 Diabetes

2017 ◽  
Vol 2017 ◽  
pp. 1-8 ◽  
Author(s):  
Anna Ramírez-Morros ◽  
Minerva Granado-Casas ◽  
Nuria Alcubierre ◽  
Montserrat Martinez-Alonso ◽  
Jordi Real ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Calcium Phosphate ◽  
Carotid Atherosclerosis ◽  
Mineral Metabolism ◽  
Intima Media Thickness ◽  
Carotid Intima Media Thickness ◽  
Inverse Association ◽  
Related Factors ◽  
Cross Sectional

Aims. To assess whether circulating 25-hydroxyvitamin D3(25OHD) and mineral metabolism-related factors (serum phosphate, calcium, and parathormone) are associated with subclinical carotid atherosclerosis (SCA), defined as the presence of carotid atherosclerotic plaques (main study outcome), in patients with type 2 diabetes mellitus (T2DM) without kidney disease or previous cardiovascular disease.Methods.We undertook a post hoc analysis of a cross-sectional study in adults with T2DM in whom we evaluated SCA. A total of 303 subjects with T2DM were included. Clinical variables and carotid ultrasound imaging were obtained.Results. We found no association of 25OHD with the presence of SCA. However, calcium phosphate (CaP; mg2/dL2) product was positively associated with the presence of carotid plaques (ORadj = 1.078; 95% CI: 1.017–1.142). An inverse association was observed between higher levels of 25OHD (≥30 ng/mL versus <20 ng/mL concentrations) and common carotid intima-media thickness (cIMT; mm) (βadj ± SE = −0.055 ± 0.024). We conclude that the CaP product is independently associated with the presence of established subclinical carotid atherosclerosis in patients with T2DM.

scholarly journals The role of Dietary Approaches to Stop Hypertension (DASH) diet food groups in blood pressure in type 2 diabetes

2011 ◽  
Vol 108 (1) ◽  
pp. 155-162 ◽  
Author(s):  
Tatiana Pedroso de Paula ◽  
Thais Steemburgo ◽  
Jussara Carnevale de Almeida ◽  
Valesca Dall'Alba ◽  
Jorge Luiz Gross ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Type 2 Diabetes ◽  
Daily Intake ◽  
Cross Sectional Study ◽  
Protective Role ◽  
Food Groups ◽  
Cross Sectional ◽  
Dash Diet

The role of each Dietary Approaches to Stop Hypertension (DASH) diet component in blood pressure (BP) of patients with diabetes is still uncertain. The aim of the present study was to evaluate possible associations of the recommended food groups of the DASH diet eating plan with BP values in patients with type 2 diabetes. In the present cross-sectional study, 225 patients with type 2 diabetes (age 61·1 (sd10·4) years; diabetes duration 13·1 (sd9·1) years; males 48·4 %; BMI 28·5 (sd4·3) kg/m2; HbA1c 7·1 (sd1·3) %; systolic BP 136·7 (sd20·0) mmHg; diastolic BP 78·4 (sd11·8) mmHg) without dietary counselling during the previous 6 months had their dietary intake assessed by 3 d weighed-diet records. Patients were divided into two groups according to BP tertiles: LOW BP (first tertile) and HIGH BP (second plus third tertiles). Multivariate logistic regression models demonstrated that the daily intake of 80 g of fruits per 4184 kJ (1000 kcal) (OR 0·781; 95 % CI 0·617, 0·987;P = 0·039) or 50 g of vegetables per 4184 kJ (1000 kcal) (OR 0·781; 95 % CI 0·618, 0·988;P = 0·040) reduced the chance of the presence of HIGH mean BP (MBP ≥ 92 mmHg) by 22 % each, adjusted for possible confounders. In conclusion, fruit and vegetables were the food groups of the DASH diet associated with reduced BP values in patients with type 2 diabetes, and their consumption might play a protective role against increased BP values.

scholarly journals Sex differences in the prevalence of obesity in 800,000 Chinese adults with type 2 diabetes

2021 ◽  
Vol 10 (2) ◽  
pp. 139-145
Author(s):  
Fang Lv ◽  
Xiaoling Cai ◽  
Chu Lin ◽  
Tianpei Hong ◽  
Xiaomei Zhang ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Sex Differences ◽  
General Population ◽  
Overweight And Obesity ◽  
Chinese Patients ◽  
Cross Sectional ◽  
Younger Age ◽  
Prevalence Of Obesity ◽  
Males And Females

Aims To estimate the sex differences in the prevalence of overweight and obesity aged 20–89 in Chinese patients with type 2 diabetes (T2D). Methods 811,264 patients with T2D from six hospital-based, cross-sectional studies, and 46,053 subjects from the general population were included in our analysis. Prevalence of underweight, overweight, obesity were calculated in each sex. Results In patients with T2D, the standardized prevalence of underweight (BMI <18.5 kg/m2), overweight (24 kg/m2 ≤ BMI < 28 kg/m2), and general obesity (BMI ≥28 kg/m2) were 2.2%, 43.2%, and 11.6%, respectively. Similar trend patterns of the prevalence of underweight and overweight were observed in general and T2D population, in males and females with T2D (all P for trend <0.01). In patients with T2D, patients at a younger age and older age were more likely to be underweight. The prevalence of overweight increased first, then stabilized or decreased with age. However, different trend patterns of the prevalence of obesity in males and females were found. In males, the prevalence of obesity decreased first, and then stabilized after 60 years of age. In females, the prevalence of obesity decreased first, then increased after 50 years of age. In the general population, the prevalence of obesity increased with age in females, while, the trend of prevalence of obesity with age in males was not obvious. Conclusion Different trends in the prevalence of obesity with age in different sex were found in Chinese patients with T2D.

scholarly journals NT-pro brain natriuretic peptide in patients with type 2 diabetes mellitus without overt heart failure: a hospital based cross sectional study

2021 ◽  
Vol 8 (4) ◽  
pp. 563
Author(s):  
Sanjay Varma ◽  
Archana Toppo ◽  
Khagdev Ram ◽  
Rajeev Lochan Khare ◽  
Yogendra Malhotra ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Heart Failure ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Brain Natriuretic Peptide ◽  
Diastolic Dysfunction ◽  
Natriuretic Peptide ◽  
Age Group ◽  
Cross Sectional

Background: Increased secretion of brain natriuretic peptide (BNP) and N-terminal proBNP (NT-proBNP) occurs mainly with increased tension in the ventricular walls, decreased oxygen supply, acute myocardial infarction, chronic cardiac heart failure, and in hypertrophy of the heart. Objective was to find out the prevalence and profile of NT-pro BNP levels in patients with type 2 diabetes mellitus (DM) without overt heart failure.Methods: Hospital based cross sectional observational study was conducted in the Department of Medicine, Pt. JNM Medical College and associated Dr. BRAM Hospital Raipur, Chhattisgarh involving 106 patients of type 2 DM during the period of April 2019 to April 2020, after ethical approval from institutional ethical committee.Results: The levels of NT pro BNP was found to be elevated in 87.7% patients of DM type 2. Majority of them were from 51-60 years age group (35.5%). Elevated NT proBNP levels was seen in 23.58% of patients having grade I diastolic dysfunction, 3.7% patients with grade II diastolic dysfunction and 1.88% patients having grade III diastolic dysfunction on echocardiography out of the 106 patients. Regardless of presence of diastolic dysfunction on echo, 93 (87.73%) patients out of the total study group of 106 patients had elevated BNP suggesting cardiac dysfunction. In the present study, 30.19% patients with diabetes were found to have varying degrees of diastolic dysfunction on echocardiography.Conclusions: The prevalence of elevated NT pro BNP was 87.7%. Commonly observed age group with elevated NT pro BNP was 51-60 years. NT pro BNP was elevated in 88.7% of males and in 88.36% of females. Prevalence of elevated NT pro BNP was higher in grade 1 diastolic dysfunction with DM duration of more than 5 years (33.3%). Higher prevalence of elevated NT pro BNP was seen in grade I diastolic dysfunction (23.58%). 

scholarly journals A Global Diet Quality Index and Risk of Type 2 Diabetes in U.S. Women

2020 ◽  
Vol 4 (Supplement_2) ◽  
pp. 1401-1401 ◽  
Author(s):  
Teresa Fung ◽  
Sabri Bromage ◽  
Yanping Li ◽  
Shilpa Bhupathiraju ◽  
Carolina Batis ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Diet Quality ◽  
Interaction Analysis ◽  
Healthy Eating Index ◽  
Quality Score ◽  
Health Study ◽  
Inverse Association ◽  
Food Groups ◽  
Health Lifestyle

Abstract Objectives No tool to measure diet quality on the global scale currently exist. At the same time, type 2 diabetes is a global issue for women, including those under age 50. As part of an effort to develop an instrument to assess diet quality, this analysis the ability of a global diet quality score to predict type 2 diabetes in women in a high-income country. Therefore, the objective of this analysis is to examine prospectively the association between the Global Diet Quality Score (GDQS) and risk of type 2 diabetes, and potential differences in association by age, among U.S. women. Methods Health, lifestyle, and diet information was collected from women (n = 88,520) in the Nurses’ Health Study II through repeated questionnaires between 1991 and 2017. The GDQS consisted of 25 food groups and points were awarded for higher intake of healthy groups and lower intake of unhealthy groups (maximum of 49 points). Multivariable hazard ratios (HR) were computed for confirmed type 2 diabetes using Cox proportional hazards models. Results We ascertained 6319 incident type 2 diabetes during follow-up. The multivariable HR comparing top to bottom quintile of GDQS was 0.83 (95% CI = 0.76–0.91, p trend &lt; 0.001). The association for women under age 50 was 0.77 (0.68–0.88, p trend &lt; 0.001) and for age 50+ was 0.69 (0.52–0.93, p trend &lt; 0.001) with no significant interaction. Analysis of the healthy and unhealthy subscores of the GDQS showed an inverse association with lower intake of unhealthy components (HR comparing top to bottom quintile of the unhealthy subscore = 0.69, 95% CI = 0.62–0.77, p trend &lt; 0.001) but not higher intake of healthy components. The inverse association for each 1-SD increase in the GDQS (HR = 0.93, CI = 0.91–0.96) was stronger (P &lt; 0.001) than the Minimum Diet Diversity score for Women (MDDW) (HR = 1.00, CI = 0.94–1.04) but slightly weaker (P = 0.03) than the Alternate Healthy Eating Index-2010 (AHEI-2010) (HR = 0.91, CI = 0.88–0.94). Conclusions A higher GDQS was inversely associated with type 2 diabetes risk in U.S. women, mainly due to lower intake of unhealthy foods. The association did not appear to differ by age. The GDQS performed nearly as well as the AHEI-2010. Funding Sources Funding for this work was provided by Intake - Center for Dietary Assessment at FHI Solutions.

scholarly journals Dietary Habits of Type 2 Diabetes Patients: Variety and Frequency of Food Intake

2016 ◽  
Vol 2016 ◽  
pp. 1-6 ◽  
Author(s):  
Senadheera Pathirannehelage Anuruddhika Subhashinie Senadheera ◽  
Sagarika Ekanayake ◽  
Chandanie Wanigatunge
Keyword(s):  
Type 2 Diabetes ◽  
Dietary Habits ◽  
Vegetable Intake ◽  
Cross Sectional Study ◽  
National Guidelines ◽  
Cross Sectional ◽  
Beneficial Effects ◽  
The University ◽  
Diabetes Patients

The objective of the present study was to observe the dietary patterns and food frequencies of type 2 diabetes patients attending the clinics of the Family Practice Center of the University of Sri Jayewardenepura, located in a highly urbanized area in Sri Lanka. An interviewer administered questionnaire based cross-sectional study was conducted among randomly selected 100 type 2 diabetes patients [age 35–70 years; mean age55±9(males = 44; females = 56)]. The data were analyzed by SPSS version 18.0 software. Vegetables, fatty foods, and poultry consumption were in accordance with the national guidelines. A significant percentage (45.5%) consumed rice mixed meals for all three meals and only 67% consumed fruits at least once a day. Majority (71%) consumed full-cream milk and sugar intake (77%) was in accordance with the guidelines. Noncaloric sweetener usage was nonexistent. Daily green leafy vegetable intake and the quantity consumed were inadequate to obtain beneficial effects. From the study population, 44% [females 50%; males 36%] of the patients were either overweight or obese. However, only 60% of those patients accepted that they were either overweight or obese. Only 14% exercised daily while 69% never exercised. Study revealed the importance of educating patients with type 2 diabetes on dietary changes and more importantly the involvement in regular physical exercises.

scholarly journals Association of apolipoproteins A1 and B with type 2 diabetes and fasting blood glucose: a cross-sectional study

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Liang Gao ◽  
Yaju Zhang ◽  
Xingmin Wang ◽  
Hongli Dong
Keyword(s):  
Type 2 Diabetes ◽  
Blood Glucose ◽  
Fasting Blood Glucose ◽  
Cross Sectional Study ◽  
Inverse Association ◽  
Sectional Study ◽  
Chinese Adults ◽  
Cross Sectional ◽  
Auc Value

Abstract Background Apolipoprotein (Apo) may be associated with type 2 diabetes (T2D), however, little is known whether or not serum apolipoproteins are correlated with fasting blood glucose (FBG) and the prevalence of T2D in Chinese populations. In this study, we examined the association of serum ApoA1, ApoB, and the ratio of ApoB/ApoA1 (ApoB/A1 ratio) with T2D and FBG level, and compared apolipoprotein indicators in predicting T2D in Chinese adults. Methods A total of 1027 subjects were enrolled in this cross-sectional study. The association of ApoA1, ApoB, and ApoB/A1 ratio with T2D prevalence was determined using logistic regression models. Multivariate-analysis of covariance (ANCOVA) was performed for comparisons of the mean difference in FBG level. Results We found that ApoB and ApoB/A1 ratio were positively associated with T2D prevalence and FBG, while inverse association was noted between ApoA1 and T2D prevalence as well as FBG. Stratified analyses for sex, age, body mass index (BMI), smoking, and alcohol consumption showed no significant difference for the association of ApoA1, ApoB, and ApoB/A1 ratio with the prevalence of T2D among subgroups (all p-interactions> 0.05). Nonetheless, ApoA1 poorly performed in predicting T2D as it provided an AUC value of 0.310 that was significantly lower than those observed for ApoB (AUC value: 0.631) and ApoB/A1 ratio (AUC value: 0.685). Finally, path analyses indicated that the association between ApoB and T2D was mediated by BMI. Conclusions This study reveals the association of serum ApoA1, ApoB, and ApoB/A1 ratio with T2D and FBG in Chinese adults, suggesting that ApoB and ApoB/A1 ratio may be early indicators for predicting T2D. Prospective investigation in large cohort is needed.

Abstract P065: The Amount and Type of Dairy Product Intake and the Risk of Incident Type 2 Diabetes: Results from the EPIC-InterAct Study

Circulation ◽  
2012 ◽  
Vol 125 (suppl_10) ◽  
Author(s):  
Ivonne Sluijs ◽  
Nita G Forouhi ◽  
Joline W Beulens ◽  
Yvonne T van der Schouw ◽  
Keyword(s):  
Type 2 Diabetes ◽  
Dairy Products ◽  
Cox Regression ◽  
Dairy Product ◽  
Diabetes Risk ◽  
Dietary Factors ◽  
Inverse Association ◽  
Food Groups ◽  
Fermented Dairy

Background: Dairy product intake may be inversely associated with risk of type 2 diabetes, but the evidence is inconclusive for total dairy products and sparse for types of dairy products. Objective: To investigate the prospective association with incidence of type 2 diabetes of total dairy products, and different dairy sub-types in populations with marked variation of intake of these food groups. Design: A nested case-cohort within 8 European countries of the EPIC Study (n=340,234; 3.99 million person-years of follow-up) included a random subcohort (n=16,835) and incident diabetes cases (n=12,403). Baseline dairy product intake was assessed using dietary questionnaires. Country-specific Prentice-weighted Cox regression hazard ratios (HR) were calculated and pooled using random effects meta-analysis. Results: Intake of total dairy products was not related to diabetes risk; HR comparing highest versus lowest quintile of total dairy products was 1.05 (95%CI: 0.91, 1.21; P-trend 0.76) in age, sex, BMI, diabetes risk factors, education and dietary factors adjusted analysis. Among dairy subtypes, an inverse association with cheese intake was present [HR 0.85 (95%CI: 0.72, 1.00); P-trend 0.01], but not with other dairy subtypes. A higher combined intake of fermented dairy products (cheese, yogurt, thick fermented milk) was inversely related to diabetes risk [HR 0.85 (0.75, 0.96), P-trend 0.01]. Conclusion: This large prospective study found no association between total dairy products and diabetes risk. The inverse association of cheese intake and combined fermented dairy product intake with diabetes risk is potentially important and merits further study.

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