scholarly journals Clinical, Ultrasonographic, Bacteriological, Cytological and Histopathological Findings of Uterine Involution in Ewes with Uterine Infection

Pathogens ◽  
2020 ◽  
Vol 9 (1) ◽  
pp. 54 ◽  
Author(s):  
Katerina S. Ioannidi ◽  
Natalia G. C. Vasileiou ◽  
Marianna S. Barbagianni ◽  
Denise C. Orfanou ◽  
George Mantziaras ◽  
...  

The objectives of the study were (a) to study the characteristics of uterine involution in ewes that had developed subclinical uterine infection in the immediately post-partum period and (b) to evaluate effects of the infection in the subsequent reproductive performance of ewes. Uterine infection was induced in ewes (I, n = 10) by intrauterine inoculation of Escherichia coli; uninoculated controls were included (C, n = 12). Animals were examined at regular intervals before and post-inoculation. Clinical and ultrasonographic examinations were performed. Vaginal swab samples and biopsy uterine tissue samples were collected for bacteriological, cytological and histological examination. Finally, ewes were put to rams and reproductive performance was monitored. After challenge, it was ultrasonographically found that caruncular dimensions, myometrial thickness and diameter of uterine lumen were greater in I ewes. In these ewes, particular reduction of dimensions occurred during the second week post-partum, whilst in C ewes during the first week. The uterine artery diameter and the blood flow into the uterus were also greater in I than in C ewes. E. coli infection was more frequent and of longer duration in I than in C ewes: in 68.1% and 50.0% of ewes and 19.5 and 14 days, respectively. There was lower proportion of neutrophils and higher of lymphocytes in group I than in C. In inoculated ewes, there was histological evidence of uterine epithelial destruction, increased cellular infiltration, hyperaemia and extracasation, which persisted up to 42 days post-partum. During the subsequent reproductive season, all ewes in group I lambed normally and produced healthy and viable lambs. No significant difference in reproductive performance parameters were seen in I comparison to C ewes. It is concluded that the innate immunity of the uterus sufficed to counteract the bacterial infection, although the process of involution took longer than in healthy animals; moreover, the ultrasonographic examination is a useful means for assessment of the genital tract of ewes post-partum; finally, no adverse effects were noted in the subsequent reproductive performance of ewes.


2019 ◽  
Vol 41 (4) ◽  
Author(s):  
Hoang Nghia Son

This study aimed to evaluate the effects of nano mineral-supplemented diet on sow productivity. The data were estimated by several parameters consisting of piglet live ratio at newborn stage and weaning stage, piglet weight at newborn stage and weaning stage, metal content in piglet livers. The results showed that live ratio of newborn piglets in group III was highest (93.44 ± 2.83%) comparing with other groups. However, there was no significant difference of live ratio in piglets at weaning stage between nano mineral-supplemented groups with control. The birth weight of piglets in nano mineral-supplemented groups was similar to control group. The birth weight of piglets in nano mineral-supplemented groups was ranged from 1,361.61 ± 47.37 grams (group II) to 1,410.48 ± 44.28 grams (group I). However, the average weight of weaned pigs in groups III and IV was higher than other groups (6,772.92 ± 105.47 grams and 6,818.87 ± 89.59 grams). Moreover, the amount of Fe, Cu, Zn, Mn in piglet liver from nano mineral-supplemented groups have been found to be lower than those in control group. These results revealed that the supplement of nano minerals for sows promoted the reproductive performance of sows and reduced mineral content in the liver of piglets. 



1966 ◽  
Vol 8 (1) ◽  
pp. 29-38 ◽  
Author(s):  
G. A. Lodge ◽  
F. W. H. Elsley ◽  
R. M. MacPherson

1. Twelve sets of 3 litter-sister Large White gilts were mated at first oestrus after reaching 250 lb. live-weight and given daily during 3 successive pregnancies either 6 lb. (A), 3 lb. (B) or 3 lb. for 76 days then 6 lb. until parturition (C) of the same meal mixture. During an 8-week lactation all were given 4 lb. meal plus 0·8 lb. per piglet suckled.2. There was a significant linear increase in numbers born with successive parities (P<0·05) but no significant differences between treatment or sister groups. There was a highly significant difference between treatment groups in mean piglet birth weight (P< 0·001) but no parity effect; mean birth weights were 2·76, 2·40 and 2·58 Ib. for Groups A, B and C respectively. Differences between sister groups in mean piglet birth weight were also significant (P<0·05).3. Post-natal litter performance was poor for all groups, probably because of the presence of E. coli, but there was no evidence of treatment effects other than on 3-week weight of third litters, which was significantly greater in Group C than in A or B (P<0·05). There were no significant effects on either number or weight of piglets at 8 weeks.



2020 ◽  
Vol 6 (2) ◽  
pp. 340-350
Author(s):  
Rashida Khaton ◽  
Md Abul Hasnat ◽  
Md Royhan Gofur ◽  
Md Zakir Hossain ◽  
Md Alauddin ◽  
...  

Performance evaluation of existing dairying is important to design relevant dairy development strategies and implement context specific interventions for future development of the dairy enterprise. The present study was carried out to evaluate the clinical trends (reproductive performance and disorders) of dairy cows of Rajshahi district, Bangladesh. A total of 500 cows randomly selected and data were collected directly from the dairy farms owners from 6 upazilas and 4 metro thanas of Rajshahi district by using questionnaires and diagnosis of reproductive disorders (RD) was made on the basis of history, clinical signs and response to treatment. The average reproductive performance (RP) were recorded as age at puberty 26.42±0.22 m, age at first calving 35.48±0.22 m, post-partum heat period 121.85±3.48 days, service per conception 1.93±0.04, days open 136.80±3.57 days and calving interval 401.04±3.94 days. The better RP was found at metro thanas compared to upazilas, though no significant difference was found except on service per conception (p<0.05). The overall prevalence of RD was 78.6% in Rajshahi district. Among the reproductive and productive disorders, anoestrus 24.6% was the highest prevalent disorders followed by abortion 13.4%, repeat breeding 11.4%, retained placenta 10.2%, dystocia 5.4%, mastitis 4.4%, vaginal prolapse 2.4%, pyometra 1.8%, metritis 1.6%, uterine prolapse 1.4%, milk fever 1.2% and still birth 0.8%. The highest occurrence of RD was recorded in Tanore upazila (92%) and the lowest in Poba upazila (62%). In comparison between the upazila and metro thanas the minimum occurrence of RD was recorded in metro thanas (31%) than upazilas (47.6%). Asian J. Med. Biol. Res. June 2020, 6(2): 340-350



Author(s):  
Rajneet Kaur ◽  
Vijay Kumar ◽  
Harjinder Singh ◽  
Geeta Walia ◽  
Arshiya Sehgal

Background: UTIs are one of the most common infectious diseases encountered in out-patient departments on day to day basis. Nitrofurantoin and Ciprofloxacin are most commonly used antibiotics in the treatment of UTI. The present study was done to compare the efficacy and tolerability of nitrofurantoin and ciprofloxacin in patients of urinary tract infection.Methods: This prospective, open, randomized, parallel group, comparative study was conducted on 60 patients presenting with acute/uncomplicated or recurrent urinary tract infection in the outpatient Department of Urology, Rajindra Hospital attached to Govt. Medical College, Patiala, Punjab. They were divided into two groups, Group I and Group II of 30 cases each. Group I patients were put on Nitrofurantoin and Group II patients were put on Ciprofloxacin. Initially 100 patients were enrolled but only those who showed growth of uropathogens on baseline urine culture or those who completed the treatment were included in the study. The primary outcome measure was microbiological eradication on post treatment urine culture.Results: The age range of the patients in Group I and Group II was 19 to 68 years (43.40±14.58 years) and 20-60 years (39.77±13.49 years) respectively. The total no. of males and females who participated in this study were 32 (53.33%) and 28 (46.66%) respectively. The most common uropathogen associated with uncomplicated UTI was E. coli (80%), other organisms detected were Klebsiella species (16.67%), Staphylococcus aureus (3.33%) and Providencia (3.33%). Post treatment urine culture results showed significant difference between two groups, 5 patients (16.67 %) in case of Group I and 14 patients (46.67%) in case of Group II showed growth of micro-organisms post treatment. P-value comes out to be 0.017 which is significant.Conclusions: In this era of super bugs, nitrofurantoin is more efficacious than ciprofloxacin in the treatment of UTI. E. coli was found to be major organism causing UTI. Ciprofloxacin is less effective due to increasing antibiotic resistance among uropathogens. Both the drugs were well tolerated, no major significant adverse effects were encountered.



1993 ◽  
Vol 33 (5) ◽  
pp. 511
Author(s):  
GJ Sawyer ◽  
J Milligan ◽  
DJ Barker

A 3-year study using 183 Angus and 173 Angus x Friesian first-calf heifers joined at about 15 months of age was conducted to determine the effects of time of calving and breed on liveweight and condition, heifer reproductive performance, oestrus activity after calving, and subsequent conception. Pasture on offer and supplements were also measured. Calving times used were April (conventional calving time), March (4 weeks earlier), and May (4 weeks later). There was no significant effect of time of calving on net reproductive rate in heifers of either breed, but the number of stillbirths and dystocias in later calved Angus were greater than in Angus x Friesian. Protracted and difficult calvings were more prevalent in heifers of both breeds calving early. Highest pregnancy rates of 93-94% corresponded with the highest average liveweights at conception in nulliparous heifers of both breeds that were mated to first-calve later. Angus x Friesian first-calvers consistently returned to oestrus before Angus after their first calving. In a year when grazing pressure on depleted dry pasture residues caused significant liveweight loss in both breeds, the crossbreds commenced cycling, on average, 20-32 days before the Angus. Regression of calving date and length of the post-partum anoestrous interval (PPAI) was -0.54 days/day for Angus and -0.3 1 days/day for Angus x Friesian. There was no significant difference between breeds for time to conception. The regression of second conception date on first calving date was 0.10 days/day in Angus and 0.17 days/day in Angus x Friesian. Heavier first-calvers of both breeds returned to oestrus earlier; each extra 10 kg in liveweight was associated with shorter PPAI by 3.9 days in Angus and 1.7 days in Angus x Friesian crossbreds. Heavier first-calvers of both breeds also conceived earlier; however, about twice as much weight was required to reduce the time to conception in the larger Angus x Friesian crossbreds than in the Angus. Times to first oestrus and to conception were negatively and linearly related to condition only in Angus first-calvers. Conception rates after first calving did not differ between time-of-calving groups or breeds in 2 years, but in a difficult year and if calved later, only 73% of Angus and 61 % of Angus x Friesians were pregnant after 90 days of joining. We conclude that there is little justification on the grounds of reproductive performance for varying the time of calving of heifers from that of the main breeding herd.



2020 ◽  
Vol 7 (2) ◽  
pp. 293-300
Author(s):  
Nevy Norma Renityas

Ibu post partum dengan Sectio secaria biasanya mengalami penurunan volume ASI sehingga tidak mencukupi kebutuhan nutrisi pada bayi. Oleh karena itu, untuk memenuhi kecukupan ASI pada bayi maka menggunakan terapi acupresure pada titik ST16, ST 17 dan ST 18 sehingga dapat menstimulasi hipofisis untuk mengeluarkan hormon prolaktin dan oksitosin. Metode penelitian yang digunakan menggunakan menggunakan pre eksperiment dengan pendekatan pre-post group design. . Sampel dalam penelitian ini berjumlah 20 ibu post partum SC, tehnik sampling yaitu tottaly sampling. Hasil penelitian membuktikan bahwa terjadi kenaikan rata-rata pada sebelum dan sesudah intervensi sebesar 310,00 poin. hasil uji Paired sample t-test didapatkan nilai  <  berarti terdapat perbedaan yang signifikan kecukupan ASI sebelum perlakuan dan sesudah perlakuan. Akupresur dapat merangsang acupoints dapat membantu mengatur proses involusi uteri dan pengeluaran ASI dan mengembalikan keseimbangan selama masa post partum. Post partum mothers with Sectio secaria usually experience a decrease in the volume of milk so that it is not sufficient for the baby's nutritional needs. Therefore, to meet the adequacy of breast milk in infants using acupressure therapy at points ST16, ST 17 and ST 18 so that it can stimulate the pituitary to secrete the hormones prolactin and oxytocin. The research method used uses pre-experiment with a pre-post group design approach. . The sample in this study amounted to 20 post partum SC mothers, the sampling technique is tottaly sampling. The results of the study prove that there was an average increase before and after the intervention of 310.00 points. Paired sample t-test results obtained value < means there is a significant difference in the adequacy of breast milk before treatment and after treatment. Acupressure can stimulate acupoints can help regulate uterine involution and milk removal and restore balance during the post partum period.



2008 ◽  
Vol 15 (03) ◽  
pp. 323-327
Author(s):  
ALIYA ISLAM ◽  
ASIFA SIRAJ ◽  
NADIA ARIF

Post partum hemorrhage (PPH) is defined as the loss of greater than 500ml of blood from the genitaltract in the first 24 hours following delivery. PPH occurs in 2-11% of all deliveries. Objective: To compare the efficacyof misoprostol and ergometrine for the prophylaxis of Post Partum Haemorrhage. Design: Prospective study. Setting:Gynaecology and Obstetrics Department Military Hospital Rawalpindi. Period: From 01 July 2006 to 31 Dec 2006.Patients & Methods: A total of 200 patients were recruited in the study, they were divided in two groups, group – I (n100) included those patients who were administered ergometrine intravenously at the time of delivery of head for theprophylaxis of post partum haemorrhage, Group – 2 (n-100) included those patients who were administered Misoprostol800 microgram per rectally just before the start of cesarean section for the same purpose. Blood loss was calculatedobjectively by squeezing the soaked pads and quantifying the amount of clots in a kidney tray of standard size to beequal to 500ml.Results: In group I (n-100) 15 patients had mild PPH blood loss >500ml, out of them 03 had severePPH requiring bimanual message and 02 patients required blood transfusion, in group II( n-100). 08 patients had PPH,blood loss >500 ml, out of them 01 patient required uterine message and none required blood transfusion. Chi-squaretest was applied to compare the efficacy of the two groups, P>0.05 showed no significant difference in the efficacy ofthe two groups but the side effects were obviously less in the Misoprostol group. No patient in group II had GI symptomswhile 36 patient in group I had retching and, vomiting and 03 patients had raised B.P after the administration ofergometrine. Conclusion: Misoprostol administered per rectally has equal efficacy to ergometrine given intravenouslyfor the prophylaxis of post partum haemorrhage but the side effect profile and patient tolerability is better withMisoprostol.



2020 ◽  
Vol 41 (4) ◽  
Author(s):  
Hoang Nghia Son

This study aimed to evaluate the effects of nano mineral-supplemented diet on sow productivity. The data were estimated by several parameters consisting of piglet live ratio at newborn stage and weaning stage, piglet weight at newborn stage and weaning stage, metal content in piglet livers. The results showed that live ratio of newborn piglets in group III was highest (93.44 ± 2.83%) comparing with other groups. However, there was no significant difference of live ratio in piglets at weaning stage between nano mineral-supplemented groups with control. The birth weight of piglets in nano mineral-supplemented groups was similar to control group. The birth weight of piglets in nano mineral-supplemented groups was ranged from 1,361.61 ± 47.37 grams (group II) to 1,410.48 ± 44.28 grams (group I). However, the average weight of weaned pigs in groups III and IV was higher than other groups (6,772.92 ± 105.47 grams and 6,818.87 ± 89.59 grams). Moreover, the amount of Fe, Cu, Zn, Mn in piglet liver from nano mineral-supplemented groups have been found to be lower than those in control group. These results revealed that the supplement of nano minerals for sows promoted the reproductive performance of sows and reduced mineral content in the liver of piglets. 



2006 ◽  
Vol 55 (7) ◽  
pp. 819-828 ◽  
Author(s):  
R. M. La Ragione ◽  
A. Best ◽  
D. Clifford ◽  
U. Weyer ◽  
L. Johnson ◽  
...  

Escherichia coli O157 : H7 and Cryptosporidium parvum infections of man have been associated with direct contact with small ruminants. Colostrum protects neonates against gastrointestinal pathogens, and orphan lambs, which are common on petting farms, may be deprived of this protection. In a recent study, it was demonstrated that high shedding of E. coli O157 : H7 by an 8-week-old goat kid was associated with coincidental C. parvum infection. Furthermore, both pathogens were co-located in the distal gastrointestinal tract. It was hypothesized that colostrum deprivation and pre-infection with C. parvum predisposed young ruminants to colonization and increased shedding of E. coli O157 : H7. To test this, 21 lambs 5 weeks of age were divided into four groups as follows: (A) colostrum-deprived and inoculated with E. coli O157 : H7, (B) colostrum-deprived and inoculated with C. parvum and then E. coli O157 : H7, (C) conventionally reared and inoculated with E. coli O157 : H7, (D) conventionally reared and inoculated with C. parvum and then E. coli O157 : H7. C. parvum was detected between 8 and 12 days post-inoculation in most of the infected lambs. At 24 h post-inoculation with E. coli O157 : H7, all lambs were shedding between 5×104 and 5×107 c.f.u. E. coli O157 : H7 per gram of faeces. E. coli O157 : H7 was shed in higher numbers in the groups pre-inoculated with C. parvum, whether conventionally reared or colostrum-deprived. Interestingly, for the colostrum-deprived lambs on day 3, a significant difference in shedding of E. coli O157 : H7 was observed (P=0.038), with the lambs inoculated with E. coli alone yielding higher counts than those pre-inoculated with C. parvum. From day 15 onwards, shedding of E. coli O157 : H7 was highest from the colostrum-deprived C. parvum-infected lambs, then (in descending order of shedding) the colostrum-deprived lambs, the conventionally reared lambs infected with C. parvum, and the conventionally reared animals. In total, four animals were euthanized, two at 24 h and two at 96 h post inoculation with E. coli O157 : H7 (two conventionally reared and two colostrum-deprived). All animals euthanized were from groups pre-inoculated with C. parvum prior to challenge with E. coli O157 : H7. On examination of tissues, in three of the four animals examined, multifocal attaching and effacing lesions were observed in the caecum, colon, rectum and at the recto-anal junction, and were confirmed by immunohistochemistry to be associated with E. coli O157 : H7.



2016 ◽  
Vol 44 (3) ◽  
pp. 166-170 ◽  
Author(s):  
MJA Mamun ◽  
MAS Khan ◽  
MAH Sarker ◽  
MN Islam

This study was done to investigate the productive and reproductive performances of Holstein Friesian crossbred (HF) and indigenous (IG) cows. A total 131 dairy cows of two genetic groups as IG (117 heads) and HF (14 heads) were selected randomly. The study found that the average milk yield per day of HF and IG cows were 7.64±1.74 and 1.75±0.07 liters/day, respectively. The milk yield was found significantly (p<0.01) higher in HF cows than of IG cows. The lactation period of HF was significantly (p<0.05) higher than of IG cows. Age at first calving of IG cows was significantly (p<0.01) 4 months higher than HF cows. The number of service per conception was almost similar for HF and IG cows. Higher significant difference was found in Post-partum oestrus (p<0.05), dry period (p<0.01), calving intervals (p<0.01) of IG than HF cows. The gestation length of HF and IG cows was significantly indifferent. Above biological studies mentioned better productive and reproductive performance of HF cows than IG cows.Bang. J. Anim. Sci. 2015. 44 (3):166-170



Sign in / Sign up

Export Citation Format

Share Document